Patents Assigned to Xiamen University
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Patent number: 11174624Abstract: A method and the device of the working bucket number identification technology during the shoveling-and-loading process of the loader uses multi-sensor fusion technology for the three kinds of pressure sensors during the shoveling-and-loading process of the loader to realize the automatic identification of the bucket number during the shoveling-and-loading process. It can effectively improve and ensure the accuracy of the test data, while effectively preventing drivers from overworking. The method and device is also beneficial to the recognition of the loader working stage, and provides a good foundation for accurately identifying the working stage and realizing the dynamic prediction and control of the working process.Type: GrantFiled: July 3, 2017Date of Patent: November 16, 2021Assignee: XIAMEN UNIVERSITYInventors: Liang Hou, Shaojie Wang, Xiangjian Bu
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Blue fluorescent powder for three primary color warm white light LED and preparation method therefor
Patent number: 11142690Abstract: The present disclosure discloses a blue fluorescent powder for a three primary color warm white LED and a preparation method thereof. SrCO3, NH4Cl, H3BO3, Eu2O3, and NH4H2PO4 function as raw materials to obtain a chemical formula of a blue fluorescent powder Sr(2-x)Eux(BO3)y(PO4)(1-y)Cl in a reducing atmosphere by a solid-state sintering method, wherein 0.001?x?0.1 and 0.001?y?0.5. The blue fluorescent powder is mixed with CaAlSiN3:Eu2+ red fluorescent powder and (SrBa)2SiO4:Eu2+ green fluorescent powder at a certain proportion to emit warm white light with a light efficiency and a color rendering index under a violet light excitation. An application prospect is wide.Type: GrantFiled: December 21, 2018Date of Patent: October 12, 2021Assignee: Xiamen UniversityInventors: Chao Chen, Xing Yang, Jiachao Chen, Yang Li -
Patent number: 11111522Abstract: The present application relates to multiplex detection of nucleic acid molecules. In particular, the present application provides a method for detecting target nucleic acid sequences, said method can simultaneously detect the presence of multiple target nucleic acid sequences in a sample. In addition, the present application further provides a probe set, and a kit comprising one or more said probe sets, said probe set and said kit can be used to carry out the method of the invention.Type: GrantFiled: April 27, 2018Date of Patent: September 7, 2021Assignee: XIAMEN UNIVERSITYInventors: Qingge Li, Dongmei Chen, Qiuying Huang, Ye Xu, Yiqun Liao
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Patent number: 11104752Abstract: Disclosed is a method for inducing orderly arrangement by means of polymer crystallization, and the use thereof in preparing a composite film. Firstly, monodisperse PS-DVB nano-microspheres of different sizes are prepared by means of soap-free emulsion polymerization; the PS-DVB nano-microspheres prepared above are used as raw material, and PEG aqueous solutions with different concentrations are added to induce an orderly arrangement of the nano-microspheres by means of solution-state PEG crystallization; and characterized by using scanning electron microscopy and polarizing microscopy. The method is simple in terms of operation and is widely applicable. By further modifying the orderly arrangement of the nano-microspheres, the composite material can be applied to different fields.Type: GrantFiled: July 5, 2019Date of Patent: August 31, 2021Assignee: Xiamen UniversityInventors: Lizong Dai, Jihong Zhu, Shangyue Chen, Yuntong Li, Conghui Yuan, Guorong Chen, Birong Zeng, Yiting Xu, Wei'ang Luo
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Publication number: 20210233511Abstract: The application discloses a multi-type acoustic feature integration method and system based on deep neural networks. The method and system include using labeled speech data set to train and build a multi-type acoustic feature integration model based on deep neural networks, to determine or update the network parameters of the multi-type acoustic feature integration model; the method and system includes inputting the multiple types of acoustic features extracted from the testing speech into the trained multi-type acoustic feature integration model, and extracting the deep integrated feature vectors in frame level or segment level. The solution supports the integrated feature extraction for multiple types of acoustic features in different kinds of speech tasks, such as speech recognition, speech wake-up, spoken language recognition, speaker recognition, and anti-spoofing etc.Type: ApplicationFiled: January 21, 2021Publication date: July 29, 2021Applicant: XIAMEN UNIVERSITYInventors: Lin LI, Zheng LI, Qingyang HONG
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Publication number: 20210228552Abstract: Provided is use of E3 ubiquitin ligase Nedd4-1 in preparation of a drug for inhibiting the Ras protein level. Also provided is use in preparation of a drug for preventing and/or treating tumors or a drug for prolonging the life span of organisms.Type: ApplicationFiled: April 25, 2019Publication date: July 29, 2021Applicant: Xiamen UniversityInventors: Hongrui WANG, Xianming DENG, Taoling ZENG, Tingting JIANG
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Patent number: 11061010Abstract: A coaxial capacitive sensor includes a sensor lubricating oil inlet and a sensor lubricating oil outlet. The sensor lubricating oil inlet and the sensor lubricating oil outlet separately communicate with the interior of the coaxial capacitive sensor. The interior of the coaxial capacitive sensor is provided with a center bearing, electrode support insulating substrates, and electrode plates. The plurality of electrode support insulating substrates and the center bearing divide the interior of the coaxial capacitive sensor into a plurality of detection sub-spaces, and the electrode plates are attached onto the electrode support insulating substrates, respectively. The coaxial capacitive sensor provided by the present invention can be arranged in a lubricating oil pipeline to avoid the influences of environmental factors on the testing results, and can on-line detect the characteristics of the lubricating oil abrasive particles efficiently.Type: GrantFiled: March 17, 2020Date of Patent: July 13, 2021Assignee: XIAMEN UNIVERSITYInventors: Yishou Wang, Yancheng You, Diheng Wu, Tingwei Lin, Xinlin Qing, Hu Sun
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Patent number: 11053122Abstract: A continuous combustion production equipment for synthesizing ton-grade fullerenes and a synthetic process therefor. The continuous combustion production equipment is equipped with a gas supply and flow control system, a liquid supply and flow control system, a vaporization and preheating system, a combustion furnace, a combustor, a spray nozzle, an ignition system, a filter tank, a product collection system, a vacuum control system, a vacuum measuring and displaying unit and a circulation water cooling system. Opening the supply line of gas fuels, arranging the tip of a metal electrode of the ignition system near the gas fuel outlet of the combustor, opening the ignition system, igniting the gas with an electric spark to generate a flame; initiating the vacuum pump set; opening the supply line of liquid raw materials, adjusting to a suitable flux with a constant flow pump; adjusting the pressure of the system to keep it below 5000 Pa.Type: GrantFiled: December 20, 2019Date of Patent: July 6, 2021Assignees: XIAMEN UNIVERSITY, JIANGXI JINSHI HIGH-TECH DEVELOPMENT CO., LTD.Inventors: Suyuan Xie, Chaoyong Fu, Miaomiao Chen, Guoyuan Wang, Xiaoming Tong, Jun Xiao, Shunliu Deng, Qianyan Zhang
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Patent number: 11046832Abstract: The present disclosure discloses a method of manufacturing silicon dioxide nanoparticles modified by a polymer containing phosphorus and nitrogen, which relates to organic/inorganic hybrid nanoparticles, dispersing SiO2 in an organic solvent, then adding THPS, stirring, and finally adding p-phenylenediamine, reacting, centrifuging, washing, and drying to obtain silicon dioxide nanoparticles modified by a polymer containing phosphorus and nitrogen. The silicon dioxide nanoparticles modified by the polymer containing phosphorus and nitrogen have effects in flame retardancy, strengthening effect of polymer matrixes, and are expected to be widely used in the halogen-free synergistic flame retardancy of polymer materials.Type: GrantFiled: September 11, 2019Date of Patent: June 29, 2021Assignee: Xiamen UniversityInventors: Lizong Dai, Chao Liu, Guorong Chen, Jiamei Huang, Zhongyu Li, Conghui Yuan, Yiting Xu, Birong Zeng, Wei′ang Luo
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Patent number: 11047943Abstract: A protocol to determine chemical shift-specific Ti constants in inhomogeneous magnetic fields is provided. Based on intermolecular double-quantum coherences and spatial encoding techniques, the method can resolve overlapped NMR spectral peaks in inhomogeneous magnetic fields acquired using conventional methods. With inversion recovery involved, the amplitude of spectral peak will be modulated by inversion recovery time. After fitting the spectral peak amplitude variation curve, the corresponding longitudinal relaxation time can be achieved. With the measured T1 values in inhomogeneous magnetic fields, insights into chemical exchange rates, signal optimization, and data quantitation can be obtained.Type: GrantFiled: December 27, 2017Date of Patent: June 29, 2021Assignee: XIAMEN UNIVERSITYInventors: Shuhui Cai, Hao Chen, Zhong Chen
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Method for preparing fluorine-silicon-containing polyphosphate ester and flame retardant epoxy resin
Patent number: 11046816Abstract: Disclosed are a fluorine-silicon-containing polyphosphate ester and method for preparation thereof, having a chemical structural formula of: wherein R1 is R2 is n=10˜100. The fluorine-silicon-containing polyphosphate ester of the present invention uses silicon phosphorus and fluorine for improving flame retardancy. Phosphorus catalyzes the system to form a phosphorus-rich carbon layer, performing a protective-layer function and thereby preventing further breakdown of the epoxy resin. The silicon-containing epoxy resin forms a silica-containing carbon layer during the process of combustion, strengthening the carbon-layer structure and further improving the protective function of the carbon-layer. The introduction of elemental fluorine improves the thermal stability of the epoxy resin, thereby improving the flame retardancy performance of the system.Type: GrantFiled: November 23, 2017Date of Patent: June 29, 2021Assignee: Xiamen UniversityInventors: Lizong Dai, Ting Chen, Cheng Liu, Shicheng Wang, Guorong Cehn, Conghui Yuan, Yiting Xu, Birong Zeng, Wei'ang Luo, Kaibin He -
Publication number: 20210134028Abstract: A method and system for simultaneous quantitative multiparametric MRI are provided in the disclosure. The method includes: designing a magnetic resonance imaging (MRI) sequence which includes a signal excitation part, a shift gradient part, and a data acquisition part; generating training samples for a deep neural network according to the MRI sequence; training the deep neural network by using the training samples, to obtain a trained deep neural network; and reconstructing multiple magnetic-resonance parametric maps by using the trained deep neural network and k-space data acquired by the MRI sequence. The disclosure can implement quantitative multiparametric MRI, and can correct image distortions caused by magnetic field inhomogeneity.Type: ApplicationFiled: November 5, 2020Publication date: May 6, 2021Applicant: Xiamen UniversityInventors: Shuhui Cai, Jian Wu, Congbo Cai
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Publication number: 20210132030Abstract: A coaxial capacitive sensor includes a sensor lubricating oil inlet and a sensor lubricating oil outlet. The sensor lubricating oil inlet and the sensor lubricating oil outlet separately communicate with the interior of the coaxial capacitive sensor. The interior of the coaxial capacitive sensor is provided with a center bearing, electrode support insulating substrates, and electrode plates. The plurality of electrode support insulating substrates and the center bearing divide the interior of the coaxial capacitive sensor into a plurality of detection sub-spaces, and the electrode plates are attached onto the electrode support insulating substrates, respectively. The coaxial capacitive sensor provided by the present invention can be arranged in a lubricating oil pipeline to avoid the influences of environmental factors on the testing results, and can on-line detect the characteristics of the lubricating oil abrasive particles efficiently.Type: ApplicationFiled: March 17, 2020Publication date: May 6, 2021Applicant: XIAMEN UNIVERSITYInventors: Yishou WANG, Yancheng YOU, Diheng WU, Tingwei LIN, Xinlin QING, Hu SUN
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Patent number: 10995061Abstract: The present disclosure is concerned with N-(5-chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)benzamide compounds that are capable of inhibiting SPAK kinase function, methods of treating hypoxic brain injuries due to, for example, ischemic stroke. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: GrantFiled: September 30, 2019Date of Patent: May 4, 2021Assignees: United States Government as Represented by the Department of Veterans Affairs, The University of Pittsburgh—of the Commonwealth of Higher Education, Xiamen University, University of ExeterInventors: Dandan Sun, Xianming Deng, Jinwei Zhang, Mohammad Iqbal Hossain Bhuiyan, Bradley J. Molyneaux
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Patent number: 10987418Abstract: The invention relates to a polypeptide carrier for presenting a target polypeptide, and use thereof. In particular, the invention relates to a nucleic acid molecule, comprising a nucleotide sequence encoding a polypeptide carrier, and being used for insertion of a nucleotide sequence encoding a target polypeptide. In addition, the invention further relates to a recombinant protein comprising the polypeptide carrier and a target polypeptide. Furthermore, the invention further relates to use of the nucleic acid molecule and the recombinant protein. In addition, the invention further relates to a vaccine or a pharmaceutical composition useful for preventing, alleviating or treating HBV infection or a disease associated with HBV infection (e.g., hepatitis B), comprising a recombinant protein comprising the polypeptide carrier of the invention and an epitope from HBV.Type: GrantFiled: February 5, 2018Date of Patent: April 27, 2021Assignees: XIAMEN UNIVERSITY, YANG SHENG TANG COMPANY, LTD.Inventors: Tianying Zhang, Quan Yuan, Xueran Guo, Minxi Wei, Xiaozhen Kang, Jun Zhang, Ningshao Xia
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Publication number: 20210095703Abstract: The present invention discloses a deflector disc of a disc tube membrane module, including a deflector disc body, radial water distribution ribs, an inner support ring and an outer support ring. a first end and a second end of the radial water distribution rib are respectively fixedly connected with an inner edge of the deflector disc body and an outer edge of the inner support ring, an annular boss is arranged on the front side of the inner support ring, a seal ring groove is respectively arranged at corresponding positions of the front side and back side of the inner support ring multiple yielding water collecting grooves are annularly and uniformly distributed on the inner surface of the inner support ring and an inner edge of the outer support ring is fixedly connected with an outer edge of the deflector disc body.Type: ApplicationFiled: January 17, 2020Publication date: April 1, 2021Applicants: CMT Membrane Technology (Xiamen) Co., Ltd., Xiamen Jiarong Technology Corp., Ltd., Xiamen University of TechnologyInventors: Rushun Wang, Zhiqun Yuan, Jing Zhou, Bin Yan, Zhipeng Ma, Tingliang Zhong
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Patent number: 10940194Abstract: Provided are a mutated HPV58 L1 protein or a variant thereof, a sequence encoding the same, a method for preparing the same, and a virus-like particle comprising the same, wherein the protein or a variant thereof and the virus-like particle can induce the generation of neutralizing antibodies against at least two HPV types, and therefore can be used to prevent infection by said at least two HPV types, and a disease caused by said infection, such as cervical cancer and condyloma acuminatum. The invention further relates to the use of the protein and the virus-like particle in the manufacture of a pharmaceutical composition or a vaccine for preventing infection by said at least two HPV types, and a disease caused by said infection, such as cervical cancer and condyloma acuminatum.Type: GrantFiled: December 2, 2016Date of Patent: March 9, 2021Assignees: Xiamen University, Xiamen Innovax Biotech Co., Ltd.Inventors: Shaowei Li, Zhihai Li, Shuo Song, Maozhou He, Ying Gu, Ningshao Xia
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Patent number: 10913040Abstract: A pressurized carbonation reaction apparatus and method thereof are provided. The apparatus comprises: an atomizing gas tank, a plurality of compressors, a plurality of buffer tanks, a plurality of pre-heaters, a pressurized liquid tank, a nozzle, a raw material tank, a carbon dioxide tank, a high-pressure reactor, a raw product tank, a feed pump, a plurality of pressure display gauges, a plurality of temperature controllers with display gauges and a plurality of back pressure valves.Type: GrantFiled: November 29, 2017Date of Patent: February 9, 2021Assignee: XIAMEN UNIVERSITYInventors: Jun Li, Qunhong Liu, Wenxin Wei, Bao Zhu, Xiaohui Hu, Hongtao Wang, Yuzhong Su, Yanzhen Hong
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Publication number: 20210023198Abstract: The disclosure relates to a mutant of hemagglutinin protein of H3N2 subtype influenza virus and use thereof. In addition, the disclosure also relates to a pharmaceutical composition (e.g., a vaccine) comprising the mutant, a method for preparing the mutant, and a method of using the mutant for prevention and/or treatment of an infection of influenza virus and/or a disease (e.g., an influenza) caused by the infection.Type: ApplicationFiled: October 10, 2018Publication date: January 28, 2021Applicant: Xiamen UniversityInventors: Yixin Chen, Chenguang Shen, Junyu Chen, Mengya Zhang, Limin Zhang, Ningshao Xia
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Publication number: 20210000938Abstract: Provided are a mutated HPV16 L1 protein (or a variant thereof), a sequence encoding the same and a method for preparing the same, as well as a virus-like particle comprising the same. The protein (or variant thereof) and the virus-like particle are capable of inducing neutralizing antibodies against at least two types of HPV (e.g., HPV16 and HPV35, or HPV16, HPV35, and HPV31), and therefore can be used to prevent infection by said at least two HPV types, and a disease caused by said infection, such as cervical cancer and condyloma acuminatum. Also provided are a use of the above protein and virus-like particle in the manufacture of a pharmaceutical composition or vaccine for preventing infection by said at least two HPV types, and a disease caused by said infection, such as cervical cancer and condyloma acuminatum.Type: ApplicationFiled: July 13, 2018Publication date: January 7, 2021Applicants: XIAMEN UNIVERSITY, XIAMEN INNOVAX BIOTECH CO., LTD.Inventors: Ying GU, Shaowei LI, Shuo SONG, Maozhou HE, Zhihai LI, Ningshao XIA