Abstract: The present invention relates to a detection mechanism for polymerase chain reaction and a polymerase chain reaction device, wherein the detection mechanism comprises at least one excitation module group, each of the excitation module groups comprising two excitation modules for providing excitation light with two wavelengths; an excitation optical fiber, connected to the excitation modules, the excitation optical fiber transmitting the excitation light to at least one reaction tube, each of the reaction tubes receiving excitation light with two wavelengths; a receiving optical fiber, for collecting and transmitting a fluorescent signal from the reaction tube; at least one receiving module group, connected to the receiving optical fiber, each of the receiving module groups comprising two receiving modules, to respectively receive the fluorescent signal of two wavelengths from the same said reaction tube, and convert the fluorescent signal into an electrical signal for output; the detection mechanism is config

Abstract: A background offset drift calibration circuit and method for comparator are proposed. The background calibration circuit and method are designed based on the approximate linear characteristic of the offset drift of a comparator caused by the variation of temperature and power supply. The calibration circuit for the comparators obtains the offset drift characteristic of each comparator by performing twice foreground calibration and selects the comparator with the largest drift as the reference comparator and other comparators as working comparators. The reference comparator is configured to track the offset drift and trigger the background calibration circuit of other working comparators. The working comparators compensate for the offset drift caused by the temperature or the power supply in the background by linear interpolation based on the offset drift characteristic of each comparator.

Abstract: Disclosed are a preparation method of a phosphorus-nitrogen-silicon-containing polymeric flame retardant and application thereof. The chemical structure of the polymeric flame retardant is wherein m=10˜100, n=10˜100. The synergistic flame-retardant effect between the phosphorus, nitrogen, and silicon in the phosphorus-nitrogen-silicon-containing polymeric flame retardant increases the flame retardancy of epoxy resin.

Abstract: Provided are a 2-mercaptobenzothiazole modified graphene oxide anti-corrosion coating and a preparation method thereof, the raw materials of which comprising, by mass ratio: 2-mercaptobenzothiazole modified graphene oxide 5-20; a matrix resin 30-70; a leveling agent 0.5-1.0; a defoamant 0.5-1.0; a dispersant 0.5-1.0; a film-forming additive 0.5-1.0; a diluent 20-35. The method for the 2-mercaptobenzothiazole modified graphene oxide comprises first reacting graphene oxide with cyanuric chloride, then reacting with 2-mercaptobenzothiazole.

Abstract: The present invention provides a type of cost-effective sulfur-based transition metal composite as the negative electrode active material for lithium ion batteries with high capacity. Moreover, a non-aqueous secondary battery using this negative electrode with long cycle life and high capacity is provided. The battery contains a positive electrode, negative electrode, separator, and non-aqueous electrolytes. The negative electrode contains at least one kind of sulfur-based transition metal composites provided in the present invention.

Abstract: A background offset drift calibration circuit and method for comparator are proposed. The background calibration circuit and method are designed based on the approximate linear characteristic of the offset drift of a comparator caused by the variation of temperature and power supply. The calibration circuit for the comparators obtains the offset drift characteristic of each comparator by performing twice foreground calibration and selects the comparator with the largest drift as the reference comparator and other comparators as working comparators. The reference comparator is configured to track the offset drift and trigger the background calibration circuit of other working comparators. The working comparators compensate for the offset drift caused by the temperature or the power supply in the background by linear interpolation based on the offset drift characteristic of each comparator.

Abstract: Provided are use of an Echovirus 25 (ECHO25) or a modified form thereof, or a nucleic acid molecule comprising a genomic sequence or cDNA sequence of the ECHO25 or a modified form thereof, or a complementary sequence of the genomic sequence or cDNA sequence, in treatment of a tumor in a subject, and in the manufacture of a medicament for treatment a tumor in a subject.

Abstract: The present invention relates to heteroaryl amide compounds, a preparation method therefor, pharmaceutical compositions thereof and applications thereof, and specifically, relates to a type of compounds having broad-spectrum tumor resistant activity, a preparation method therefor, pharmaceutical compositions containing the compounds, and uses of the compounds in the preparation of drugs for treating tumors.

Abstract: A protocol to determine chemical shift-specific T1 constants in inhomogeneous fields. Based on intermolecular double-quantum coherences and spatial encoding techniques, the method can resolve overlapped peaks in inhomogeneous fields using the conventional method. With inversion recovery involved, the amplitude of peaks will be modulated by the time of inversion recovery. After fitting the amplitude curves, the corresponding longitudinal relaxation time can be achieved. With the measured T1 values in inhomogeneous fields, we can have insights into the chemical exchange rates, signal optimization and data quantitation.

Abstract: This invention provides a NMR multi-dimensional method for measuring coupling constants within several coupling networks. At first, a 90° hard pulse was performed to flip the magnetization from the Z axis to the XY plane. After t1/2, a selective 180° pulse is implemented with a simultaneous Z-direction gradient, thus reversing different protons at different slices. Then the PSYCHE element is implemented. After another t1/2, the gradient G1 and Gp are implemented. At last, the EPSI readout is used to simultaneously record both the chemical-shift and the spatial information. As a result, from different specific slices, we can extract the scalar couplings between the proton reversed at this slice and other protons. These couplings lead to splittings in the indirect dimension, from which relevant coupling constants can be measured.

Abstract: A method for underwater acoustic communication includes steps of S1: capturing a synchronization signal using a replica correlation operation; S2: performing time reversal forward shift processing and time reversal backward shift processing, respectively, on the synchronization signal to obtain a forward shift time reversal coefficient and a backward shift time reversal coefficient; S3: performing a convolution operation of the forward shift time reversal coefficient and the backward shift time reversal coefficient, respectively, with a subsequently captured information sequence to obtain a forward shift time reversal output and a backward shift time reversal output; S4: processing the forward shift time reversal output and the backward shift time reversal output, respectively, with a forward shift equalizer and a backward shift equalizer to obtain two sets of equalizer outputs; and S5: selecting one of the two sets of equalizer outputs with a smaller error for data decoding to obtain a desired signal.

Abstract: A method and the device of the working bucket number identification technology during the shoveling-and-loading process of the loader uses multi-sensor fusion technology for the three kinds of pressure sensors during the shoveling-and-loading process of the loader to realize the automatic identification of the bucket number during the shoveling-and-loading process. It can effectively improve and ensure the accuracy of the test data, while effectively preventing drivers from overworking. The method and device is also beneficial to the recognition of the loader working stage, and provides a good foundation for accurately identifying the working stage and realizing the dynamic prediction and control of the working process.

Abstract: Provided are an ORF7 deficient varicella virus, an vaccine comprising the virus and use thereof, as well as a method for the production the virus.

Abstract: Provided are an enterovirus D68 (EV-D68) or a modified form thereof, or a nucleic acid molecule comprising a genomic sequence or cDNA sequence of the EV-D68 or a modified form thereof, or a complementary sequence of the genomic sequence or cDNA sequence, or a pharmaceutical composition comprising the EV-D68 or a modified form thereof, or the nucleic acid molecule, and use of the EV-D68 or a modified form thereof, or the nucleic acid molecule in the manufacture of a pharmaceutical composition for treating a tumor.

Abstract: A combined cycle propulsion system (CCPS) module combines a low-speed propulsion system (LSPS) such as a turbojet and a high-speed propulsion system (HSPS) such as dual mode ramjet engines with a mid-speed propulsion system (MSPS) such as a ejector ramjet engine to close a thrust gap between the upper operation limit of the LSPS and the lower operation limit of the HSPS in a flight vehicle. A cooling system ensures thermal protection of the non-operating LSPS during MSPS or HSPS operation by cooling tapped air from the MSPS or HSPS using a heat exchanger and expansion in a turbine/generator and directing cooled tapped air into the LSPS.

Abstract: The invention relates to a method for embedding a load based on gel high hydrostatic pressure liquefaction. Using the phenomenon that the physical gel is liquefied under high pressure, the vacuum-packaged high-methoxyl pectin gel is treated under a pressure of 400-600 MPa for 5-30 min, mixed with the load, and then subjected to a pressure of 400-600 MPa for homogenization treatment for 5 to 30 min After pressure relief, the liquefied gel is poured into a mold for reshaping, followed by removal of free water and coating treatment. This method combines the advantages of high hydrostatic pressure technology in modification and sterilization. It has mild embedding conditions and wide sources of raw materials to prepare the carrier, which has excellent biocompatibility and biodegradability. It can be widely used for embedding microorganisms, enzymes, proteins and small molecular substances. The loaded gel prepared by the method has high microbial safety, can effectively maintain the activity of the load.

Abstract: The invention relates to a truncated rotavirus VP4 protein, a sequence encoding the same, a method for preparing the same, and a pharmaceutical composition and a vaccine comprising the protein, wherein the protein, the pharmaceutical composition and the vaccine are useful for preventing, alleviating or treating rotavirus infection and a disease caused by rotavirus infection, such as rotavirus gastroenteritis and diarrhea. The invention further relates to use of the protein in the manufacture of a pharmaceutical composition or a vaccine for preventing, alleviating or treating rotavirus infection and a disease caused by rotavirus infection, such as rotavirus gastroenteritis and diarrhea.

Abstract: An anticorrosion treatment method for a copper-containing material comprises: carrying out a sealed and pressurized reaction on a copper-containing material and a stabilizer in presence of a polar solvent and any assistant, the stabilizer being a compound capable of providing formates, so that the formates are adsorbed on the surface of the copper-containing material. In the method, formates are modified on the surface of the copper-containing material, accordingly, the oxidation resistance capability and the stability of the copper-containing material can be significantly improved while the electrical conductivity of the copper-containing material is not reduced, and the corrosion resistance of the copper-containing material and especially, the salt and alkali corrosion resistance of the copper-containing material are significantly improved.

Abstract: Provided are a broad-spectrum monoclonal anti-Flu B antibody, cell strains generating the antibody, and a composition comprising the antibody; also provided are uses of the antibody for diagnosing, preventing and/or treating an infection of the Flu B and/or diseases caused by the infection.

Abstract: A continuous combustion production equipment for synthesizing ton-grade fullerenes and a synthetic process therefor. The continuous combustion production equipment is equipped with a gas supply and flow control system, a liquid supply and flow control system, a vaporization and preheating system, a combustion furnace, a combustor, a spray nozzle, an ignition system, a filter tank, a product collection system, a vacuum control system, a vacuum measuring and displaying unit and a circulation water cooling system. Opening the supply line of gas fuels, arranging the tip of a metal electrode of the ignition system near the gas fuel outlet of the combustor, opening the ignition system, igniting the gas with an electric spark to generate a flame; initiating the vacuum pump set; opening the supply line of liquid raw materials, adjusting to a suitable flux with a constant flow pump; adjusting the pressure of the system to keep it below 5000 Pa.