Patents Assigned to Zoetis Services LLC
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Patent number: 11524068Abstract: This invention relates to a method of treating a dog for canine diseases comprising administering to the dog therapeutically effective amounts of a vaccine, wherein the vaccine comprises viral antigens, a bacterin, or both, and wherein the vaccine is administered subcutaneously or orally according to the schedules provided herein.Type: GrantFiled: June 24, 2020Date of Patent: December 13, 2022Assignee: Zoetis Services LLCInventors: Cassius McAllister Tucker, John David Haworth
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Publication number: 20220356231Abstract: Provided herein are immunogenic compositions that may be used, in some aspects, to induce an immune response against an Ehrlichia such as Ehrlichia cams. In some embodiments, the immunogenic composition comprises an E. canis bacterin and/or adjuvant, such as for example an emulsion or liposomal adjuvant. Related methods such as for diagnosis of or vaccination against ehrlichiosis are also provided.Type: ApplicationFiled: July 13, 2020Publication date: November 10, 2022Applicants: Research Development Foundation, Zoetis Services LLCInventors: Jere W. McBRIDE, Paul J. DOMINOWSKI, Suman MAHAN, Jason J. MILLERSHIP, Duncan M. MWANGI, Sharath RAI, Sharon M. WAPPEL
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Patent number: 11474034Abstract: A lateral flow test system having an optical reader, a lateral flow cartridge and a computer system is provided. The lateral flow cartridge includes a porous test strip with a reading window into the porous test strip exposing an exposed zone of the porous strip. The optical reader has a reader housing and a slot for inserting the cartridge into the reader housing. The optical reader has an illumination arrangement adapted for illuminating the exposed zone of the porous strip when the cartridge is inserted into the slot. The optical reader further has a video camera configured for acquiring a series of digital images comprising the exposed zone of the porous strip. The computer system receives sets of pixel data representing the plurality of consecutive digital images and calculates wetting progress along the length of the exposed zone of the porous strip based on the sets of pixels data.Type: GrantFiled: March 9, 2018Date of Patent: October 18, 2022Assignee: Zoetis Services LLCInventors: Carl Esben Poulsen, Johan Eriksen, Martin Heller, Niels Kristian Bau-Madsen
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Patent number: 11464849Abstract: The invention relates to recombinant viral vectors for the insertion and expression of foreign genes for use in safe immunizations to protect against a variety of pathogens. The invention also relates to multivalent compositions or vaccine comprising one or more recombinant viral vectors for protection against a variety of pathogens. The present invention relates to methods of making an using said recombinant viral vectors.Type: GrantFiled: September 10, 2020Date of Patent: October 11, 2022Assignee: Zoetis Services LLCInventors: Sing Rong, Yugang Luo, Tyler Brown
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Patent number: 11453854Abstract: An improved stabilization buffer for use in the lyophilization of Neospora and other protozoans is disclosed. Also disclosed is an improved lyophilization method, which includes controlling ice nucleation during the freezing step.Type: GrantFiled: October 4, 2017Date of Patent: September 27, 2022Assignee: Zoetis Services LLCInventors: Rim Daoussi, Frederick H. Weber
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Patent number: 11446324Abstract: The present disclosure relates generally to sol-gel polymer composites that comprise chitosan, a hydrophilic polymer, a polysiloxane, and a gelation agent in a suitable medium. Advantageously, the sol-gel polymer composite can form a durable seal or strong solid in response to one or more physiological stimulus. The disclosure further relates to medical and veterinary uses of the composite, particularly, methods and delivery systems for reducing or preventing the incidence of a mammary disorder in a dairy animal. More particularly, the disclosure includes methods and sol-gel polymer composite compositions for creating a physical barrier on the teat surface or in the teat canal or cistern of a non-human animal for prophylactic treatment of mammary disorders such as mastitis wherein the sol-gel polymer creates a seal in response to one or more physiological stimulus.Type: GrantFiled: April 19, 2018Date of Patent: September 20, 2022Assignee: Zoetis Services LLCInventors: Christina Lee Brown, Derek James Sheehan, John Mark Heimlich, Todd Foster, Jeffrey Ellis Price, Sumitra Rajagopalan, Alexandre Therrien, Oscar Suarez, Nicholas Finn Cunningham
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Patent number: 11433139Abstract: A vaccine composition for immunizing and/or protecting a mammal against an IL-31 mediated disorder is provided, wherein the composition includes: the combination of a carrier polypeptide and at least one mimotope selected from a feline IL-31 mimotope, a canine IL-31 mimotope, a horse IL-31 mimotope, and a human IL-31 mimotope; and an adjuvant. Such vaccines can be in the form of pharmaceutical compositions useful for treating or protecting mammals such as cats, dogs, horses, or humans against IL-31-mediated disorders.Type: GrantFiled: March 18, 2019Date of Patent: September 6, 2022Assignee: Zoetis Services LLCInventors: Gary Francis Bammert, Steven Alan Dunham
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Patent number: 11389518Abstract: Disclosed herein are Mycoplasma bovis immunogenic compositions useful in raising an immune response in animals against M. bovis. Also disclosed herein are methods for generating a protective response against infections in mammals caused by M. bovis.Type: GrantFiled: August 11, 2016Date of Patent: July 19, 2022Assignees: Zoetis Services LLCInventors: Glenn Francis Browning, Philip Francis Markham, Marc Serge Marenda, Fred H. Weber, Suman Mahan
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Patent number: 11370177Abstract: Described herein are various embodiments directed to rotor devices, methods, and systems. Embodiments of rotors disclosed herein may be used to characterize one or more analytes of a fluid. A method may include bonding a first layer and a second layer using two-shot injection molding. The first layer coupled to the second layer may collectively define a set of wells. The first layer may be substantially transparent. The second layer may define a channel. The second layer may be substantially absorbent to infrared radiation. A third layer may be bonded to the second layer using infrared radiation. The third layer may define an opening configured to receive a fluid. The third layer may be substantially transparent. The channel may establish a fluid communication path between the opening and the set of wells.Type: GrantFiled: August 22, 2019Date of Patent: June 28, 2022Assignee: Zoetis Services LLCInventors: Robert Justice Shartle, Gregory Trigub
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Patent number: 11369958Abstract: Described herein are various embodiments directed to rotor devices, systems, and kits. Embodiments of rotors disclosed herein may be used to characterize one or more analytes of a fluid. An apparatus may include a first layer being substantially transparent. A second layer may be coupled to the first layer to collectively define a set of wells. The second layer may define a channel, and the second layer may be substantially absorbent to infrared radiation. A third layer may be coupled to the second layer. The third layer may define an opening configured to receive a fluid. The third layer may be substantially transparent. The channel may establish a fluid communication path between the opening and the set of wells.Type: GrantFiled: August 22, 2019Date of Patent: June 28, 2022Assignee: Zoetis Services LLCInventors: Robert Justice Shartle, Gregory Trigub
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Patent number: 11351243Abstract: The invention provides isolated polynucleotide molecules that comprise a DNA sequence encoding an infectious RNA sequence encoding a genetically-modified North American PRRS virus, methods to make it and related polypeptides, polynucleotides, and various components. Vaccines comprising the genetically modified virus and polynucleotides and a diagnostic kit to distinguish between naturally infected and vaccinated animals are also provided.Type: GrantFiled: March 4, 2020Date of Patent: June 7, 2022Assignee: Zoetis Services LLCInventors: Jay Gregory Calvert, David Ewell Slade, Siao-Kun W. Welch
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Patent number: 11352396Abstract: Antimicrobial peptides of general formula X0X1X2C X3X4X5CX6X7X8X9CYX10X11CX12X13 are provided. Also provided are certain formulations containing these peptides and methods of using these peptides for treating skin infections in an animal in need thereof.Type: GrantFiled: December 5, 2018Date of Patent: June 7, 2022Assignee: Zoetis Services LLCInventors: Michael Kuhn, Christopher A. Zook, Derek James Sheehan, Eric Baima, Richard Andrew Ewin, Hilary Phelps
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Patent number: 11351244Abstract: The invention provides isolated polynucleotide molecules that comprise a DNA sequence encoding an infectious RNA sequence encoding a genetically-modified North American PRRS virus, methods to make it and related polypeptides, polynucleotides, and various components. Vaccines comprising the genetically modified virus and polynucleotides and a diagnostic kit to distinguish between naturally infected and vaccinated animals are also provided.Type: GrantFiled: March 18, 2020Date of Patent: June 7, 2022Assignee: Zoetis Services LLCInventors: Jay Gregory Calvert, Robert G. Ankenbauer, Jacqueline Gayle Marx, Douglas S. Pearce, Marcia L. Keith
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Patent number: 11351239Abstract: The invention provides isolated polynucleotide molecules that comprise a DNA sequence encoding an infectious RNA sequence encoding a genetically-modified North American PRRS virus, methods to make it and related polypeptides, polynucleotides, and various components. Vaccines comprising the genetically modified virus and polynucleotides and a diagnostic kit to distinguish between naturally infected and vaccinated animals are also provided.Type: GrantFiled: August 2, 2019Date of Patent: June 7, 2022Assignee: Zoetis Services LLCInventors: Jay Gregory Calvert, Robert G. Ankenbauer, Jacqueline Gayle Marx, Douglas S. Pearce, Marcia L. Keith
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Patent number: 11337787Abstract: A vaccination system for delivering a vaccine substance to avian pullets is provided. Such a system includes a vaccine delivery assembly configured to perform a vaccine delivery procedure for delivering a vaccine substance to the avian pullets. A plurality of positioning devices is provided, with each positioning device receiving an avian pullet for presentation to the vaccine delivery assembly. Each positioning device is transported to individually mate with the vaccine delivery assembly to deliver the vaccine substance during the vaccine delivery procedure. Associated methods, devices, and assemblies are also provided.Type: GrantFiled: May 7, 2019Date of Patent: May 24, 2022Assignee: Zoetis Services LLCInventor: William Douglas Samson
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Patent number: 11331369Abstract: The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R1, R2, R3, R4, L1, and L2, are as defined herein. The present invention also contemplates compositions and methods of treatment as an endoparasiticide with a Formula (1) compound.Type: GrantFiled: November 28, 2018Date of Patent: May 17, 2022Assignee: Zoetis Services LLCInventors: Michael P. Curtis, Susan M. Sheehan, Graham M. Kyne, Matthew W. Bedore, Richard A. Ewin, Paul D. Johnson, Tom L. McTier, Christoper S. Knauer, Rajendran Vairagoundar
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Patent number: 11318200Abstract: The invention provides a substantially antigen-free composition for induction of innate immune response in a bird or a mammal, the composition comprising a saponin, a sterol, a quaternary amine, and a polyacrylic polymer to the mammal or bird. Methods of using the composition are also provided.Type: GrantFiled: November 21, 2014Date of Patent: May 3, 2022Assignee: Zoetis Services LLCInventors: Paul Joseph Dominowski, Duncan Mwangi, Joseph M. Bricker, Dennis L. Foss, Sharath K. Rai, Suman Mahan
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Patent number: 11255854Abstract: The present invention provides methods, devices, compositions (e.g., capture complexes), and kits useful for enhancing the detection of antibodies in a test sample. The methods, devices, and compositions utilize detectable Fc-binding molecules such as Protein A, Protein G, and/or an Fc-specific antibody to amplify the signal of a detected antibody in immunoassays, such as lateral flow assays.Type: GrantFiled: March 20, 2019Date of Patent: February 22, 2022Assignee: Zoetis Services LLCInventors: Rajesh K. Mehra, Kenneth P. Aron, Dennis M. Bleile, Jeremy Walker, Cristina Cuesico
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Patent number: 11248257Abstract: A nucleic acid probe, a method of immobilizing the nucleic acid probe to a solid support and the solid support including the immobilized probes using UV light. The nucleic acid probe includes a terminus anchor chain portion, and a capture portion wherein the terminus anchor chain portion includes a sequence of at least 18 nucleotides composed of stretches of up to 5 nucleotides of base type X with intermediate nucleotide(s) of base type Cytosine (C) and optionally one nucleotide of base type Guanine (G) or a sequence with at least 90% similarity thereto, wherein each base type X independently of each other designate base type Thymine (T) or base type Uracil (U).Type: GrantFiled: August 24, 2018Date of Patent: February 15, 2022Assignee: ZOETIS SERVICES LLCInventors: Johan Eriksen, Wai Hoe Chin, Martin Jensen Søe, Martin Heller
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Patent number: 11226324Abstract: An egg identification system for determining viability of an avian egg is provided. Such a system includes an emitter assembly configured to emit electromagnetic radiation having a predetermined wavelength toward an egg. A detector assembly is spaced-apart from the emitter assembly and configured to detect electromagnetic radiation transmitted through the egg. A light controlling assembly is positioned proximate to the emitter assembly. The light controlling assembly includes an absorbing layer configured to absorb electromagnetic radiation at the predetermined wavelength. The absorbing layer defines an opening through which electromagnetic radiation emitted from the emitter assembly is capable of passing therethrough toward the egg. A processor is configured to process an output signal of the detector assembly to determine viability of the egg. An associated method is also provided.Type: GrantFiled: March 6, 2020Date of Patent: January 18, 2022Assignee: Zoetis Services LLCInventors: William Dongwook Suh, Joel James Walukas