Patents Examined by Abigail Vanhorn
  • Osteogenic biomaterial
    Patent number: 11028140
    Abstract: A composition for enhancing bone tissue repair or regeneration is described. The composition includes osteoactivin or an active peptide fragment thereof and a biocompatible material. Osteogenic orthopedic devices including the osteoactivin-containing composition are also described. The devices and compositions can be used in methods for enhancing bone tissue repair or regeneration by contacting a site in need of bone repair or regeneration in a subject with the osteoactivin-containing composition.
    Type: Grant
    Filed: September 22, 2015
    Date of Patent: June 8, 2021
    Assignee: Northeast Ohio Medical University
    Inventor: Fayez Safadi
  • Pharmaceutical compounding methods and systems
    Patent number: 10993876
    Abstract: The present disclosure relates to a system and process for manufacturing patient personalized pharmaceutical compositions using superimposed revolution and rotation movements for dispersing, milling, melting, and/or de-aerating, where these superimposed revolution and rotation movements can be carried out in a single device in a pharmacy setting.
    Type: Grant
    Filed: April 1, 2019
    Date of Patent: May 4, 2021
    Assignee: MEDISCA PHARMACEUTIQUE INC.
    Inventors: Panagiota Danopoulos, Marc Joiner, Sarah Nyat Peng Wong, Vargha Talebi
  • Drug releasing coatings for medical devices
    Patent number: 10994055
    Abstract: Medical device are provided for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent and an additive. In certain embodiments, the additive has a hydrophilic part and a drug affinity part, wherein the drug affinity part is at least one of a hydrophobic part, a part that has an affinity to the therapeutic agent by hydrogen bonding, and a part that has an affinity to the therapeutic agent by van der Waals interactions. In embodiments, the additive is water-soluble. In further embodiments, the additive is at least one of a surfactant and a chemical compound, and the chemical compound has a molecular weight of from 80 to 750 or has more than four hydroxyl groups.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: May 4, 2021
    Assignee: Lutonix, Inc.
    Inventor: Lixiao Wang
  • Polylactic acid-containing aqueous dispersion
    Patent number: 10987299
    Abstract: Provided is a polylactic-acid-containing aqueous dispersion capable of forming a transparent film at room temperature. A polylactic-acid-containing aqueous dispersion contains (1) polylactic acid; (2) at least one plasticizer selected from the group consisting of dimethyl adipate, diethyl adipate, dipropyl adipate, diisopropyl adipate, dibutyl adipate, diallyl adipate, bis(2-butoxyethyl) adipate, bis(2-methoxyethyl) adipate, dimethyl succinate, dimethyl glutarate, diethyl sebacate, diisopropyl sebacate, and mixtures thereof; (3) at least one dispersion stabilizer selected from the group consisting of cationic polymers, anionic polymers, polyvinyl alcohols, and non-ionic surfactants; and (4) water.
    Type: Grant
    Filed: January 25, 2016
    Date of Patent: April 27, 2021
    Assignees: TOYOBO CO., LTD., DAITO KASEI KOGYO CO., LTD.
    Inventors: Shuhei Yamamoto, Yoshihisa Kasukabe, Chikako Yamashita, Takumi Tanaka, Noboru Nagatani
  • Compositions containing identical polyamine salts of mixed anionic pesticides
    Patent number: 10980237
    Abstract: The present invention relates to a composition comprising a first salt, which contains a first anionic pesticide (A1) and a cationic polyamine (B), and a second salt, which contains a second anionic pesticide (A2) and a cationic polyamine (B), wherein both salts contain the same cationic polyamine (B), and wherein the cationic polyamine comprises at least two amino groups. The disclosure further relates to methods for preparing the composition, methods for combatting harmful insects and/or phytopathogenic fungi using the composition, methods for controlling undesired vegetation using the composition, and seeds including the composition.
    Type: Grant
    Filed: November 2, 2011
    Date of Patent: April 20, 2021
    Assignee: BASF SE
    Inventors: Adam Hixson, Steven Bowe, Wen Xu
  • Decontamination solution and its use for denaturation, modification, degradation, solubilisation and removal of proteins, nucleic acid molecules and microorganisms
    Patent number: 10980239
    Abstract: The invention concerns a three component system comprising surface-active substances, vitamins and metal ions for efficient destruction and removal of contaminating proteins, nucleic acids and microorganisms from surfaces like for example laboratory benches, floors, equipment and instruments. These non-corrosive and non-toxic solutions for removal of proteins, nucleic acids and microorganisms are applied by spraying, rubbing or immersion of contaminated surfaces thereby destroying, solubilizing inactivating and removing proteins and nucleic acids. In that way also microorganisms are killed with high efficiency and at the same time all genetic information is inactivated.
    Type: Grant
    Filed: October 2, 2017
    Date of Patent: April 20, 2021
    Inventors: Thomas Lisowsky, Karlheinz Esser, Richard Lisowsky
  • Anti-allergenic ocular compositions and eyelid cleansing wipes
    Patent number: 10959940
    Abstract: An anti-allergenic composition comprising from about 0.01% to about 50% by weight of a polyphenol, from about 0.01% to about 50% by weight of a terpene compound, and from about 0.001% to about 10% by weight of a glycolipid. The polyphenol has a flavanol derivative. The terpene compound can be selected from the group consisting of a terpene, terpinene, a terpene derivative and combinations thereof. In an embodiment, the sphingolipid comprises about 0.2% phytosphingosine.
    Type: Grant
    Filed: July 11, 2019
    Date of Patent: March 30, 2021
    Assignee: OCuSOFT INC.
    Inventors: Nat Adkins, Jr., Troy Smith, Paramita Sarkar
  • Fumarate ester dosage forms
    Patent number: 10945985
    Abstract: Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In particular, oral controlled release pharmaceutical compositions comprising fumarate esters suspended in liquid matrices are described. One embodiment described herein is a pharmaceutical composition comprising fumarate esters suspended in a lipid or lipophilic liquid with enhanced bioavailability.
    Type: Grant
    Filed: September 13, 2018
    Date of Patent: March 16, 2021
    Assignee: BANNER LIFE SCIENCES LLC
    Inventors: Jason M. Vaughn, Justin R. Hughey, Tanesha Roberts, Tatyana Dyakonov, Sunil Agnihotri, Aqeel A. Fatmi
  • Methods and compositions for wound healing
    Patent number: 10940120
    Abstract: The present invention relates to methods and compositions for wound healing. In particular, the present invention relates to promoting and enhancing wound healing by utilizing cross-linker covalent modification molecules to attach and deliver wound active agents to a wound. In addition, the present invention provides methods and compositions utilizing oppositely charged polymers to form a polyelectrolyte layer on a wound surface. The invention further relates to incorporating wound active agents into a polyelectrolyte layer for delivery to a wound.
    Type: Grant
    Filed: April 28, 2014
    Date of Patent: March 9, 2021
    Assignee: IMBED BIOSCIENCES, INC.
    Inventors: Jonathan F. McAnulty, Christopher Murphy, Nicholas Abbott
  • Gel patch
    Patent number: 10940121
    Abstract: A method for producing a gel patch comprising an adhesive mass layer on a backing fabric, comprising a step of applying a composition comprising a physiologically active substance, a water-soluble polymer, glycerin, and water to the backing fabric to form the adhesive mass layer, wherein a loss tangent of the composition in dynamic viscoelasticity measurement at 1 Hz at a time of application to the backing fabric is 0.75 to 1.
    Type: Grant
    Filed: February 17, 2016
    Date of Patent: March 9, 2021
    Assignee: HISAMITSU PHARMACEUTICAL CO., INC.
    Inventors: Seiichiro Tsuru, Masayoshi Maki
  • Tetrazolinone compound and use thereof
    Patent number: 10939681
    Abstract: The present invention provides a compound having excellent control efficacy against pests, especially Lepidoptera pests. A compound represented by formula (1) has excellent control efficacy against pests, especially Lepidoptera pests.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: March 9, 2021
    Assignee: SUMITOMO CHEMICAL COMPANY, LIMITED
    Inventors: Takashi Ikehara, Norio Kimura
  • Fumarate ester pharmaceutical compositions
    Patent number: 10918617
    Abstract: Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In particular, oral pharmaceutical compositions comprising fumarate esters are described.
    Type: Grant
    Filed: September 13, 2018
    Date of Patent: February 16, 2021
    Assignee: BANNER LIFE SCIENCES LLC
    Inventors: Tatyana Dyakonov, Sunil Agnihotri, Aqeel A. Fatmi
  • Fumarate esters
    Patent number: 10918615
    Abstract: Described herein are pharmaceutical compositions comprising one or more fumarate esters, processes for making the same, and compositions and methods for treating multiple sclerosis subjects with the compositions. In particular, oral pharmaceutical compositions comprising fumarate esters in liquid vehicles are described. One embodiment is an oral delayed release pharmaceutical dosage form comprising a soft capsule encapsulating an immediate releasing liquid comprising one or more fumarate esters.
    Type: Grant
    Filed: September 13, 2018
    Date of Patent: February 16, 2021
    Assignee: BANNER LIFE SCIENCES LLC
    Inventors: Jason M. Vaughn, Justin R. Hughey, Tanesha Roberts, Tatyana Dyakonov, Sunil Agnihotri, Aqeel A. Fatmi
  • Skin compositions and methods of use thereof
    Patent number: 10918661
    Abstract: The present invention provides durable, natural looking, non-invasive compositions that exhibit desired aesthetic qualities for therapeutic treatments. Specifically, the compositions can be used for the treatment of wounds and headaches. In addition, the compositions of the invention can be used to deliver agents to the subject in need thereof. In one embodiment, the invention pertains, at least in part, to methods for treating wounds, comprising applying to a subject's skin a formulation comprising a) a first reactive reinforcing component; and b) a second cross-linking component; in which the cross-linking component catalyzes an in situ cross-linking of the reactive reinforcing component, such that a film is formed on the wound, thereby treating the wound.
    Type: Grant
    Filed: April 6, 2018
    Date of Patent: February 16, 2021
    Assignee: Shiseido Company, Limited
    Inventors: Betty Yu, Joseph Lomakin, Soo-Young Kang, Benjamin W. Adams
  • Fumarate ester pharmaceutical compositions
    Patent number: 10918616
    Abstract: Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In particular, oral pharmaceutical compositions comprising fumarate esters are described.
    Type: Grant
    Filed: September 13, 2018
    Date of Patent: February 16, 2021
    Assignee: BANNER LIFE SCIENCES LLC
    Inventors: Tatyana Dyakonov, Sunil Agnihotri, Aqeel A. Fatmi
  • Combination formulation of three antiviral compounds
    Patent number: 10912814
    Abstract: Disclosed are pharmaceutical compositions comprising three antiviral compounds. In particular, the pharmaceutical compositions comprise an effective amount of velpatasvir, an effective amount of sofosbuvir, and an effective amount of voxilaprevir. Also disclosed are methods of use for the pharmaceutical composition.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: February 9, 2021
    Assignee: Gilead Pharmasset LLC
    Inventors: Ben Chal, Elham Nejati, Rowchanak Pakdaman, Dimitrios Stefanidis
  • Liquid sulfonylurea herbicide formulations
    Patent number: 10912298
    Abstract: Disclosed are single liquid-phase herbicide compositions comprising by weight, from 0.1 to 20% of one or more sulfonylurea herbicides, from 0 to 40% of one or more biologically active agents other than sulfonylurea herbicides, from 0.1 to 20% of one or more lignosulfonates, from 0 to 99.8% of one or more fatty acid esters of C1-C4 alkanols, and from 0 to 50% of one or more additional formulating ingredients.
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: February 9, 2021
    Assignee: E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: George B. Beestman, James J. Reap
  • Glyphosate salt herbicidal composition
    Patent number: 10912302
    Abstract: A process is provided for preparing a glyphosate salt solution that comprises potassium and IPA cations in a desired mole ratio, and that has a glyphosate a.e. concentration not less than about 400 g/l. The process includes adding glyphosate acid to a glyphosate potassium salt solution having a glyphosate assay of at least about 40% a.e. by weight, to form a slurry. The process also includes introducing isopropylamine, in an amount sufficient to neutralize the added glyphosate acid, to the slurry with mixing until all glyphosate is dissolved, to form a mixed glyphosate salt solution comprising potassium and IPA cations in the desired mole ratio.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: February 9, 2021
    Assignee: Monsanto Technology LLC
    Inventors: Henry Agbaje, David R. Eaton, Jeffrey A. Graham
  • Microparticles
    Patent number: 10905660
    Abstract: The present invention provides microparticles comprising a sulphur-containing compound, such as cysteamine, or a pharmaceutically acceptable salt, hydrate or ester thereof. Also provided is a composition comprising the microparticles and a stabilizing agent.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: February 2, 2021
    Assignee: NOVABIOTICS LIMITED
    Inventor: Deborah O'Neil
  • Pharmaceutical composition comprising dabigatran etexilate, and preparation method, solid preparation and use thereof
    Patent number: 10881615
    Abstract: A pharmaceutical composition comprising dabigatran etexilate, and preparation method and use thereof, and solid preparation comprising the pharmaceutical composition; the pharmaceutical composition comprises a vitamin C layer and a dabigatran etexilate layer separated by a semipermeable film layer, and the semipermeable film layer comprises a water-soluble compound, a water-insoluble compound and an optional anti-sticking agent and/or plasticizer.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: January 5, 2021
    Assignee: Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
    Inventors: Xiongxiong He, Ping Dong, Jiahui Cai, Xin Huang, Xiquan Zhang