Patents Examined by Abigail Vanhorn
  • Nanoparticles for immune stimulation
    Patent number: 10881720
    Abstract: The invention relates, in part, to nanoparticles, methods for preparing nanoparticles and methods of administering nanoparticles for immune stimulation. An immune-stimulating nanoparticle of the invention may include, at least in part, a polymer substrate comprising a biodegradable polymer and may include at least one antigen and/or at least one adjuvant.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: January 5, 2021
    Assignees: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, RENSSELAER POLYTECHNIC INSTITUTE
    Inventors: Elizabeth Leadbetter, Eyal Amiel, Emilie Vomhof-Dekrey, Robert Lindhardt, Amanda MacDonald, Jianjun Maio
  • Controlled release oral pharmaceutical dosage forms comprising MGBG
    Patent number: 10881626
    Abstract: Disclosed herein are controlled-release oral pharmaceutical dosage forms comprising MGBG, and their application for the improved treatment of diseases with reduced side effects and/or longer time at maximum concentration.
    Type: Grant
    Filed: May 1, 2017
    Date of Patent: January 5, 2021
    Assignee: Pathologica LLC
    Inventors: John McKearn, Jeremy Blitzer
  • Sunscreen compositions containing a UV-absorbing polyglycerol and a non-UV-absorbing polyglycerol
    Patent number: 10874603
    Abstract: A sunscreen composition including a polymer composition that contains a UV-absorbing polyglycerol having a UV-absorbing chromophore chemically bound thereto, and a cosmetically-acceptable topical carrier that contains at least one percent by weight of the sunscreen composition of a non-UV-absorbing polyglycerol, based on total weight of the sunscreen composition.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: December 29, 2020
    Assignee: Johnson & Johnson Consumer Inc.
    Inventors: Susan Daly, Prithwiraj Maitra, Barry Setiawan
  • Production method for organopolysiloxane emulsion composition
    Patent number: 10870734
    Abstract: A production method for an organopolysiloxane emulsion composition, wherein (I) an emulsion composition is prepared from an organopolysiloxane (A) that is represented by formula (1) and that has an octamethylcyclotetrasiloxane content of 1,000 ppm or less HO(R12SiO)nH??(1), (wherein R1 is H or a monovalent hydrocarbon group and n is a number that makes the viscosity, at 25° C., of the organopolysiloxane 200 mm2/s or more but less than 2,000 mm2/s), a surfactant (B) that is represented by formula (2) and that has an alkyl naphthalene skeleton R2a—C10H(7-a)—SO3M??(2), (wherein R2 is an alkyl group, M is H+, an alkali metal ion, an alkali earth metal ion, NH4+, or a tertiary NH4+, and m is 1-3), and water (C-1), and wherein (II) water (C-2) is added as necessary and then emulsion polymerization is performed in the presence of an acid catalyst (D).
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: December 22, 2020
    Assignee: SHIN-ETSU CHEMICAL CO., LTD.
    Inventors: Akihiro Kobayashi, Yuko Takada, Takuya Abe
  • Sustained release nanocomposite, a process for producing the same and use thereof
    Patent number: 10857236
    Abstract: The present invention relates to nanocomposites for the controlled delivery of active ingredients into the central nervous system. The nanocomposite according to the present invention comprises a biocompatible core part comprising biodegradable material, and polyelectrolytes able to form a electrostatic van der Waals interactions with the material of the core part. The core part of the nanocomposite is able to bind various pharmaceutical agents. The present invention also relates to a process for the preparation of the nanocomposite according to the present invention and to the use of the nanocomposite according to the present invention.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: December 8, 2020
    Assignee: Szegedi Tudományegyetem
    Inventors: Imre Dékány, István Krizbai, Zsófia Majláth, József Toldi, Noémi Varga, László Vécsei
  • Emulsified fatty acids
    Patent number: 10835491
    Abstract: Provided herein are methods and processes for emulsifying non-polar compounds, such as omega fatty acids. Also provided are compositions that can be prepared according to the methods and processes described herein. The compositions, for example, have a high amount of the non-polar compound, such as a large amount of omega fatty acids. The non-polar compounds are also present in very small droplets within composition. For example, the mean or median particle size of the droplets is less than about 5 ?m. Further, the composition includes a low amount of surfactant, such as less than about 10-15% of the surfactant.
    Type: Grant
    Filed: October 3, 2018
    Date of Patent: November 17, 2020
    Assignee: BARLEAN'S ORGANIC OILS, LLC
    Inventor: Peter Nguyen
  • Click-crosslinked hydrogels and methods of use
    Patent number: 10821208
    Abstract: The present disclosure provides click-crosslinked hydrogels and methods of use.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: November 3, 2020
    Assignee: President and Fellows of Harvard College
    Inventors: Rajiv Desai, Neel Satish Joshi, David J. Mooney, Sandeep T. Koshy, Alexander G. Stafford
  • Edible animal medicine container
    Patent number: 10821073
    Abstract: An edible animal medicine container for delivering medicine or other ingestible material, contained therein, to an animal, includes first and second edible housing shells. The first shell include a first opening defined by a first peripheral ledge having a periphery that is surrounded by a second peripheral ledge that is stepped down from, and connected via a first wall to, the first peripheral ledge. A peripheral lip is disposed around the first wall. The second shell includes a second opening defined by a third peripheral ledge surrounding, and connected via a second wall to, a fourth peripheral ledge which is recessed into the second opening. The first and second shells are positionable into a closed state wherein the first peripheral ledge, the first wall, and the peripheral lip are inserted into the second opening so as to retain the ingestible material within the interior until ingested by an animal.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: November 3, 2020
    Assignee: Make Ideas, LLC
    Inventor: Keith Alan Mullin
  • Antibacterial medical implant surface
    Patent number: 10814046
    Abstract: Aspects include methods of fabricating antibacterial surfaces for medical implant devices including patterning a photoresist layer on a silicon substrate and etching the silicon to generate a plurality of nanopillars. Aspects also include removing the photoresist layer from the structure and coating the plurality of nanopillars with a biocompatible film. Aspects also include a system for preventing bacterial infection associated with medical implants including a thin silicon film including a plurality of nanopillars.
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: October 27, 2020
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Stacey M. Gifford, Huan Hu, Emily R. Kinser, Roy R. Yu, Sufi Zafar
  • Emulsified fatty acids
    Patent number: 10813883
    Abstract: Provided herein are methods and processes for emulsifying non-polar compounds, such as omega fatty acids. Also provided are compositions that can be prepared according to the methods and processes described herein. The compositions, for example, have a high amount of the non-polar compound, such as a large amount of omega fatty acids. The non-polar compounds are also present in very small droplets within composition. For example, the mean or median particle size of the droplets is less than about 5 ?m. Further, the composition includes a low amount of surfactant, such as less than about 10-15% of the surfactant.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: October 27, 2020
    Assignee: BARLEAN'S ORGANIC OILS, LLC
    Inventor: Peter Nguyen
  • Compositions and methods for the treatment and prevention of chronic hypoxemia and dyspnea
    Patent number: 10813893
    Abstract: The present invention has shown that not all salts of pyruvic acid enhance lung functions or enhance the synthesis of lung surfactants and that certain salts of pyruvic acid with the correct concentrations of calcium, phosphate and magnesium, are synergistic in their ability to enhance the synthesis of lung surfactants that will enhance lung alveoli functions, while decreasing coughing and lung tightness, and increasing oxygen saturation values to prevent hypoxemia. This patent demonstrates that the sodium pyruvate formula with calcium, phosphate and magnesium was superior over standard sodium pyruvate formula in saline alone in the removal of mucus, reduction of lung or sinus infections, and in reducing drug side effects and congestion.
    Type: Grant
    Filed: February 24, 2017
    Date of Patent: October 27, 2020
    Assignee: CELLULAR SCIENCES, INC.
    Inventor: Alain Martin
  • Methods and formulations for curling hair
    Patent number: 10792233
    Abstract: Methods, formulations, and kits for curling and/or preventing damage in the curling of hair are disclosed herein. Hair can be curled by treatment with hydroxide-containing agents, in combination with one or more active agents, without the need for thiol-based or peroxide-based agents. The active agent can be applied simultaneously with the hydroxide-containing agent, to impart curl to the hair. They may be applied as a combined formulation or as separate formulations applied simultaneously. Use of the active agent along with a hydroxide-containing agent can be used to control the level of curl imparted to hair, as compared to the natural amount of curl, if any, in the untreated hair.
    Type: Grant
    Filed: December 27, 2017
    Date of Patent: October 6, 2020
    Assignee: OLAPLEX, INC.
    Inventors: Eric D. Pressly, Craig J. Hawker
  • Labile esters of agrochemicals for controlled release and reduction of off-site movement
    Patent number: 10793503
    Abstract: The present invention relates to esters of carboxylic acid agrochemicals comprising a labile protecting group and having formula (I). Certain of the esters of carboxylic acid agrochemicals do not undergo hydrolysis to a significant degree in the dark, but are cleaved to regenerate the parent carboxylic acid agrochemical when exposed to light. Others of the esters of carboxylic acid agrochemicals undergo hydrolysis under both light and dark conditions. The present invention further relates to methods for the controlled release of a carboxylic acid agrochemicals, and to methods of controlling unwanted plants comprising applying to the unwanted plants an ester of a carboxylic acid agrochemical.
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: October 6, 2020
    Assignee: Monsanto Technology LLC
    Inventor: David A. Morgenstern
  • White keratin compositions
    Patent number: 10792239
    Abstract: The invention provides white keratin protein compositions and methods of making and using white keratin protein compositions.
    Type: Grant
    Filed: May 5, 2015
    Date of Patent: October 6, 2020
    Assignee: Kernnetics, Inc.
    Inventors: Luke Burnett, Elizabeth Kneller, Erin Falco
  • Stabilized formulations of 4-amino-3-substituted butanoic acid derivatives
    Patent number: 10792262
    Abstract: Pharmaceutical compositions including an active ingredient and a stabilizer, as well as methods of manufacture of the compositions, and methods of their use.
    Type: Grant
    Filed: July 29, 2019
    Date of Patent: October 6, 2020
    Assignee: SAOL INTERNATIONAL LIMITED
    Inventors: David Penake, Sharon Hamm, Leonard O'Mahony, John Devane, Wolfgang Mohr, Manuel Weinheimer
  • Liquid polymer delivery system for extended administration of drugs
    Patent number: 10786515
    Abstract: Liquid polymer pharmaceutical compositions with a biodegradable liquid polyester that has a carboxylic acid end group, a biocompatible solvent, and an active pharmaceutical agent are useful for administration into the body to provide extended long term release of the drug.
    Type: Grant
    Filed: August 3, 2016
    Date of Patent: September 29, 2020
    Assignee: Tolmar International Limited
    Inventors: John Milton Downing, Vipin Saxena, John Middleton
  • Aqueous pesticide microemulsion
    Patent number: 10785973
    Abstract: The present invention relates to an aqueous pesticide microemulsion formulation including (a) at least one organic pesticide compound P, which is sparingly soluble in water and which is present in the formulation in dissolved form; (b) at least one organic solvent LM1 selected from C1-C4-alkyl lactates; (c) at least one organic solvent LM2 selected from C5-C12-alkyl lactates; (d) at least one organic solvent LM3 selected from N—(C4-C12 alkyl)pyrrolidones; (e) at least one surfactant S selected from anionic surfactants and non-ionic surfactants and mixtures thereof; and (f) water.
    Type: Grant
    Filed: September 2, 2015
    Date of Patent: September 29, 2020
    Assignee: BASF SE
    Inventors: Claude Taranta, Steffen Schlehuber, Sarah Thompson, Wolfgang Meier, Jochen Schreieck, Helmut Mueller, Paulo Cesar Queiroz
  • Benzoic acid herbicide composition
    Patent number: 10772323
    Abstract: An emulsifiable concentrate comprising a benzoic acid herbicide in acid form dissolved in an amide solvent and an amide solvent and an amine emulsion stabiliser.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: September 15, 2020
    Assignee: NUFARM AUSTRALIA LIMITED
    Inventors: Sumit Sharma, Aristos Panayi, Chad Richard Ord Sayer
  • Pesticidal microcapsules with a shell made of tetramethylxylylene diisocyanate, cycloaliphatic diisocyanate, and aliphatic diamine
    Patent number: 10765112
    Abstract: The present invention relates to a composition comprising microcapsules, which comprise a polyurea shell and a core, wherein the core comprises a water-insoluble pesticide and the shell comprises a polymerization product of a tetramethylxylylene diisocyanate, an cycloaliphatic diisocyanate, and an aliphatic diamine; to a method for preparing the composition comprising the steps of contacting water, the pesticide, the tetramethylxylylene diisocyanate, the cycloaliphatic diisocyanate, and the aliphatic diamine; and to a method of controlling phytopathogenic fungi and/or undesired plant growth and/or undesired insect or mite attack and/or for regulating the growth of plants, wherein the composition is allowed to act on the respective pests, or the crop plants to be protected from the respective pest, on the soil and/or on undesired plants and/or on the crop plants and/or on their environment.
    Type: Grant
    Filed: May 10, 2016
    Date of Patent: September 8, 2020
    Assignee: BASF SE
    Inventors: Klaus Kolb, Wolfgang Gregori, Ulrich Steinbrenner, Liliana Parra Rapado
  • Methods for improving plant growth-monitoring
    Patent number: 10765118
    Abstract: Methods of improving the growth of a plant by applying a plant growth effective amount of a plant growth composition that includes a hydrated aluminum-magnesium silicate and at least one dispersant selected from the group consisting of a sucrose ester, a lignosulfonate, an alkylpolyglycoside, a naphthalenesulfonic acid formaldehyde condensate and a phosphate ester to plant propagation material in the absence of insect pest pressure.
    Type: Grant
    Filed: October 10, 2016
    Date of Patent: September 8, 2020
    Assignee: FMC Corporation
    Inventors: Timothy M. Martin, Frank Zawacki