Abstract: A test container including: at least two accommodation portions each accommodating a liquid and internally provided; a flow path connecting the two accommodation portions to each other at respective upper end positions thereof internally provided; and a flexible film deformable inwards of at least one accommodation portion at a portion forming an upper wall surface of the one accommodation portion, in which the liquid accommodated in the one accommodation portion is fed to the other accommodation portion via the flow path due to deformation of the flexible film towards the one accommodation portion, and a breaking elongation of the flexible film is 100% or more and 600% or less.

Abstract: Disclosed herein is a device detecting volatile organic compounds, such as acetone, using nanostructured K2W7O22 crystals. Methods for detecting a subject in a state of ketosis, such as diabetes, using a volatile organic sensing device are disclosed. A method for synthesizing K2W7O22 nanostructured sensing crystals is further disclosed.

Abstract: A thermal history detection label for detecting a thermal history over a temperature range to be monitored while suppressing an increase in label size is provided. The thermal history detection label is configured to detect a thermal history by the permeation of a molten permeating material into a permeation body, and the thermal history detection label includes a permeating material that integrally includes a first permeating material having a first melting point and a second permeating material having a second melting point higher than the first melting point, and a permeation body into which the permeating material permeates.

Abstract: A sample extraction chip and a biological reaction device are disclosed according to the present disclosure. The sample extraction chip includes a chip body and a sample extraction module provided on the chip body, the sample extraction module includes a sample-loading lysis unit, a liquid release-control unit, an extraction unit, a liquid switch-control unit, a liquid collection unit and a sample collection unit, which are connected through flow channels in a sequence of extraction. The liquid release-control unit is configured to store and release liquid reagents, and the liquid switch-control unit is configured to switch between communication of the liquid collection unit and the extraction unit and communication of the sample collection unit and the extraction unit. The sample collection unit includes a front collection portion and a rear collection portion which are both in communication with the liquid switch-control unit.

Abstract: Disclosed herein are microfluidic devices and methods to deliver concentration gradients to biological material such as oocytes and embryos for the purpose of cryopreparation, cryopreservation, or thawing. Cryopreservation methods, such as vitrification, involve the use of cryoprotectants to reduce formation of damaging ice crystals in cells during freezing. Microfluidic devices and methods described herein improve cell viability and efficiency during handling and cryopreservation of biological materials.

Abstract: A microfluidic device for polymerase chain reaction (PCR) processing includes a platform with a microstructure with at least one reaction chamber, and a heating element. The heating element heats at least a part of the at least one reaction chamber. The heating element includes at least one spin torque oscillator (STO) configured to heat the at least a part of the at least one reaction chamber to one or more temperatures for PCR processing.

Abstract: Method, apparatus, and computer program product are provided for anonymized diagnosis using lateral flow assays. In some embodiments, a test card includes one or more lateral flow assay (LFA) with one or more test patterns (e.g., full line, partial line, dot), one or more dummy patterns, and one or more control patterns. To visually encode LFA results, at manufacture, one or more lines/dots containing true results of the LFA(s) each has a position mixed with other “dummy” lines/dots, in randomized position patterns selected from among a plurality of possible position patterns. An optical machine-readable representation of data (e.g., QR code) is attached to the test card and encodes test card identification information (e.g., lot number, serial number, test type) associated with the test card. In some embodiments, a passcode card having a scrapeable coating that conceals a passcode associated with the test card is removably attached to the test card.

Abstract: A method of making an article bonding a layer of deformable material to a surface of a cartridge body having at least one valve body thereon to seal the at least one valve body, the valve body comprising a valve floor and valve walls comprising upper parts, wherein the valve floor is recessed from the surface and the valve walls extend from the surface to the valve floor, and wherein the valve body comprises walls that are curved or sloped in a direction that is non-normal to the plane defined by the surface; and deforming the layer such that upon release of a force causing the deformation, the layer is in contact with the upper parts of the valve walls and is in spaced from the valve floor so as to bias the valve to an open state.

Abstract: A method for manufacturing modified metal nanoparticles includes steps as follows. Metal nanoparticles are provided, wherein each of the metal nanoparticles is a gold nanoparticle or a silver nanoparticle. An ascorbic acid solution is provided, wherein the ascorbic acid solution includes ascorbic acid molecules and/or ascorbic acid ions. A surface modification step is conducted, wherein the metal nanoparticles and the ascorbic acid solution are mixed, such that surfaces of the metal nanoparticles are modified by the ascorbic acid molecules and/or ascorbic acid ions to obtain the modified metal nanoparticles.

Abstract: A biosensor component is provided that provides enhanced characteristics for use in biosensors, such as blood glucose sensors. The biosensor component comprises a substrate, a conductive layer deposited on the substrate, and a resistive material layer deposited on the conductive layer. The conductive layer includes nickel, chromium, and iron, such that a combined weight percent of the nickel and chromium in the conductive layer is in the range of 25 to less than 95 weight percent, the weight percent of nickel in the conductive layer is at least 4 weight percent, the weight percent of chromium in the conductive layer is at least 10 weight percent, the weight percent of iron in the conductive layer at least 2 weight percent, and such that the conductive layer comprises 0 to 20 weight percent molybdenum.

Abstract: A multiplexed testing strip testing device includes a hydrophobic paper-based strip housing element configured for placement of one or more testing strips. One or more alignment markers on the hydrophobic paper-based housing element are marked to facilitate placement of the one or more testing strips. A cover element is arranged above the strip housing element and includes a machine-readable test identifier on an upper surface. A removably attached filtering element is arranged on the hydrophobic paper-based strip housing element.

Abstract: Devices, systems, and methods are provided for monitoring or analyzing excreta of a subject using a toilet. In one embodiment, the device includes a housing mounted adjacent a toilet bowl, a urinalysis module for deploying urinalysis strips into the toilet bowl to collect a urine sample from a subject's urine stream delivered into the toilet bowl and a urinalysis sensor to acquire data from the urinalysis strip related to the urine sample, and a stool analysis module including a camera oriented into the toilet bowl to provide images of contents of the toilet bowl. In addition, the device may include a uroflowmetry module and/or a biometric identification module. One or more sensors are provided for identifying when a subject uses the toilet, and a processor activates one or more of the modules when the sensors indicate a subject is using the toilet.

Abstract: Fluidic systems and reagent carriers suitable for storing reagents in a desirable manner are generally provided. In some embodiments, a reagent carrier stores a liquid film comprising a solid reagent and/or stores different reagents in different locations. In some embodiments, a fluidic system comprises a reagent carrier constrained such that it comprises an elongated axis positioned within 30° of a vertical axis of the fluidic reservoir.

Abstract: A lab-on-a-cartridge (LOAC) handheld assay device including an integrated test cartridge, a carbon nanotube electrode sensor, and a reagent dispenser for dispensing a liquid reagent into the test cartridge. The test cartridge includes a syringe plunger for drawing a test fluid into a test cavity, a bottom wall with a reagent inlet port, and a vibration adaptor for mixing. The reagent input port is attached with a slit valve for engaging with a slit spout of the reagent dispenser as a needleless dispensing system. Carbon nanotube sensors of different three-electrode configurations are provided for testing a volume of test fluid to increase the electrochemical reaction sensitivity. The assay device can be used with a CNT three-electrode sensor for saliva testing for determining glucose concentration.

Abstract: The present disclosure discloses a microfluidic structure, a microfluidic chip and a detection method. The microfluidic structure includes: a first base substrate and a second base substrate opposite to each other, an antibody area located between the first base substrate and the second base substrate and storing an enzyme-labeled first antibody, a cleaning area storing cleaning liquid, a signal substrate area storing a signal substrate solution and a detection area with a second antibody and an ion sensitive film fixed thereon, wherein all channel areas from the antibody area, the cleaning area and the signal substrate area to the detection area each have a driving electrode structure driving liquid drops to move; and the detection area has a thin film transistor connected with the ion sensitive film.

Abstract: An indicator and method of use thereof, and indicator system and method of use thereof are provided to determine the degree of an oxidative treatment. An indicator is incorporated into the oxidative treatment. The object and the indicator are subjected to the oxidative treatment. A discoloration of the indicator occurs based on an oxidation of the polymer by a process condition of the oxidative treatment oxidizing the polymer. The discoloration of the indicator is measured against a threshold color value to determine the degree of the oxidative treatment.

Abstract: An automatic human urine detection system comprises a control module, a urine collection module, a detection module, an output module and a cleaning module. The control module controls operation of the system and comprises an instruction input unit. The urine collecting module is used for collecting urine to be detected; the detection module comprises a detection probe holder which is used for detecting the urine to be collected and obtains a corresponding detection report according to a detection result; the output module is used for outputting the detection report; and the cleaning module is used for cleaning system components through which the urine flows or is stored in the system. The automatic human urine detection system integrates automatic collection and subsequent automatic detection of human urine, the whole urinalysis process is effectively simplified, the operation process is humanized, and the user experience is good.

Abstract: A method and device for detecting pyrethroid pesticide residues in crops. Reaction membrane is arranged on a bottom plate and provided with a check-up line and a quality control line; a first mounting block and a second mounting block are arranged on the bottom plate; a first slide is arranged in the first mounting block, a second slide is arranged in the second mounting block; a sample pad and a bonding pad are arranged in the first slide; a water absorption pad is arranged in the second slide; a liquid inlet provided with a pipe is formed in the first mounting block, a pressing hole provided with a press block is formed in the second mounting block; protrusions are respectively formed on the pipe and the press block; sliding grooves are formed in the liquid inlet and the pressing hole; and first springs are arranged between the protrusions and the sliding grooves.

Abstract: A kit for performing an assay for determining an analyte in a sample with an extended shelf-life, wherein the kit comprises a chemiluminescent cyclic dihydrazide, an enhancer, a co-enhancer, and a peroxide oxidizer. The kit is useful in blot assays and immunoassays for the detection of proteins and nucleic acid molecules.

Abstract: A sample of blood is placed on a bilirubin test strip and plasma separated from the red blood cells. The bilirubin test strip is located on a test card along with a set of calibration images, the colors of the calibration images being associated with known plasma bilirubin levels. A photograph is taken of the test card. The bilirubin level of the blood sample is determined by, within the photograph, interpolating the color of the plasma and the colors of the closest colored calibration images.