Patents Examined by Alea N. Martin
  • Patent number: 11536665
    Abstract: The present disclosure relates to a novel absorbance-based colorimetric device system, and to methods of using the novel absorbance-based colorimetric device system.
    Type: Grant
    Filed: August 11, 2020
    Date of Patent: December 27, 2022
    Assignee: Purdue Research Foundation
    Inventors: Justin A Weibel, Suresh V Garimella, Aditya Chandramohan
  • Patent number: 11534752
    Abstract: An embodiment includes a sample receiving region, a first diagnostic element that includes one or more colorimetric analysis regions, and a second diagnostic element that includes one or more lateral flow assay analysis regions. The embodiment also includes a first flow path that allows a portion of a liquid deposited at the sample receiving region to flow to the first diagnostic element. The embodiment also includes a second flow path that allows a portion of the liquid deposited at the sample receiving region to flow to the second diagnostic element.
    Type: Grant
    Filed: December 30, 2020
    Date of Patent: December 27, 2022
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Ademir Ferreira da Silva, Jaione Tirapu Azpiroz, Matheus Esteves Ferreira, Mathias B Steiner, Daniel Vitor Lopes Marcondes Marçal
  • Patent number: 11519904
    Abstract: The invention provides device and method for detecting infection in a body fluid, in particular in wound exudates and urine, based on protease activity. The device is founded on a detector consisting of one layer, which is an absorbent layer impregnated with a solution formed by dissolving a pH sensitive dye, such as bromothymol blue, in a gelatin solution. The method uses the device in form of a test strip for quick detection of an infection by observing a change in the color of the detector.
    Type: Grant
    Filed: July 4, 2020
    Date of Patent: December 6, 2022
    Inventor: Soheila Salahshoor Kordestani
  • Patent number: 11517896
    Abstract: A test strip device including a housing, at least one retention arm, an ejection tab, and a viewing window. The housing includes a channel extending through the housing, with an opening at a first end of the housing, the channel being configured to receive a test strip therein. The at least one retention arm is arranged within the channel and configured to retain the test strip within the channel. The ejection tab is slideably arranged within the housing and configured to slide the test strip through the channel and out of the opening. The viewing window is arranged within the housing and configured to allow a results region of the test strip disposed within the channel to be viewed through the viewing window.
    Type: Grant
    Filed: August 14, 2020
    Date of Patent: December 6, 2022
    Assignee: Luna Pharmaceuticals, Inc.
    Inventor: Dan Aziz
  • Patent number: 11506657
    Abstract: The present invention provides a detection device comprises a testing element and a transparent area, wherein the testing element comprises a detection area which is configured to detect a presence of an analyte in a liquid sample; the transparent area is configured to read the test result on the detection area through the transparent area; a part of the transparent area contacts a part of the detection area, or the detection area and the transparent area are arranged in one sealed space, thus to make the air in the sealed space not exchange with the air outside the sealed space; the scheme can reduce the mist to ensure the test result is displayed clearly.
    Type: Grant
    Filed: July 29, 2020
    Date of Patent: November 22, 2022
    Assignee: HANGZHOU BIOTEST BIOTECH CO., LTD.
    Inventors: Shujiang Wu, John Wu, Liang Hong, Yangyu Zhu
  • Patent number: 11499969
    Abstract: A multi-layered band and a method for manufacturing a multi-layered band are disclosed. The multi-layered band comprises a support (1) to hold at least one battery structure (10) formed by overlapped layers including a porous material (11) and two electroactive electrodes (12, 13), one oxidizing (12) and one reducing (13), separated at a certain distance between them and in touch with said porous material (11). The battery structure (10) is configured to be activated upon the addition of a fluid into a given region of the porous material (11) and to provide electrical energy while said fluid impregnates by capillarity the porous material (11). The overlapped layers are constituted by parallel strips extending longitudinally along the length of the support (1), such that said multi-layered band can be cut transversally providing individual batteries of a same or different width each including the porous material (11) and the electroactive electrodes (12, 13).
    Type: Grant
    Filed: May 13, 2019
    Date of Patent: November 15, 2022
    Inventors: Juan Pablo Esquivel Bojorquez, Maria de les Neus Sabate Vizcarra, Marc Castellarnau Aymar, Sergi Gasso Pons
  • Patent number: 11498069
    Abstract: A rapid test device includes a micropad chip configured for a multi-parameter chemical testing of an input sample. A plurality of paper layers of the micropad chip are in fluid communication, including a sample absorption element, a filtering element configured to filter the input sample, and a sample distribution element configured to distribute the input sample received from the filtering element to a remainder of the plurality of paper layers. One or more reacting elements associated with the multi-parameter chemical testing of the input sample have one or more colorimetric reagents in fluid communication with the sample distribution element. A colorimetric result displaying element in fluid communication with the one or more reacting elements is configured to display a colorimetric result of the testing of the input sample with the at least one reacting element for a respective chemical test of the multi-parameter chemical testing.
    Type: Grant
    Filed: August 31, 2020
    Date of Patent: November 15, 2022
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Ademir Ferreira da Silva, Daniel Vitor Lopes Marcondes Marçal, Jaione Tirapu Azpiroz, Matheus Esteves Ferreira, Mathias B. Steiner, Ricardo Luis Ohta
  • Patent number: 11484881
    Abstract: Diagnostic systems for sensing biological molecules are disclosed. The diagnostic systems include a fluid control delivery and control system that can be coupled to a diagnostic cartridge that includes a microfluidic device and integrated sensing electronics. The diagnostic systems can be used to sequence biological molecules.
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: November 1, 2022
    Assignee: AXBIO INC.
    Inventors: Albert Chueh, Stephen F. Dreyer, Priyanka Agrawal, Igor Ivanov, Hui Tian
  • Patent number: 11486832
    Abstract: A lateral flow diagnostic testing apparatus including a measurement assembly in which a cartridge is loaded and which is inclined with respect to a main body housing in a lateral flow direction of the cartridge is disclosed. The main body housing and the measurement assembly is rotatably hinge-coupled to adjust an inclination angle. The inclination of the measurement assembly is adjustable by an inclination driving unit. A vibration actuator can be further included on a cartridge loading surface. In addition, a heating unit fixed to face the cartridge can be further included.
    Type: Grant
    Filed: May 5, 2021
    Date of Patent: November 1, 2022
    Assignee: Pebble-i Inc.
    Inventor: Soohong Kim
  • Patent number: 11480539
    Abstract: The purpose of the present invention is to provide a method for accurately measuring and controlling intracellular potential by a simple method that is less invasive to the cell and does not require a skilled technique. The present invention makes it possible to provide an intracellular recording electrode inside the cytoplasm by introducing conductive nanoparticles into a cell cultured on a conductive plate electrode, attracting the conductive nanoparticles inside the cell to the side of the cell adhered to the conductive plate electrode, and causing the conductive nanoparticles to pass through the cell membrane. Measuring the current or voltage between the intracellular recording electrode and an extracellular electrode in extracellular solution makes it possible to measure the intracellular potential.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: October 25, 2022
    Assignee: Ion Chat Research Corporate
    Inventor: Mitsuyoshi Saito
  • Patent number: 11441173
    Abstract: Described herein are instruments for excitation and detection of fluorophores in a plurality of functional regions in a biochip, using an excitation source and a steering element that directs a beam from the excitation source to a plurality of functional regions in the biochip, wherein the excitation source excites the fluorophores in the plurality of functional regions generating a signal that is detected such that said signal from at least one of the plurality of functional regions allows for nucleic acid quantification. Also described are systems for quantification and separation and detection using optical devices adapted for preliminary, simultaneous or sequential quantitation of nucleic acid in separate detection positions, and for the excitation and detection of multiple samples to steer both the excitation and detection beam paths to separately image each lane of a biochip.
    Type: Grant
    Filed: December 27, 2019
    Date of Patent: September 13, 2022
    Assignee: ANDE CORPORATION
    Inventors: Eugene Tan, Richard F. Selden, Rosemary S. Turingan
  • Patent number: 11428640
    Abstract: A urine test device includes a case in which a guide is formed, a strip tray including a strip moving body formed to be slidably movable through the guide, a plurality of strip seating parts formed on the strip moving body, and a strip fixing part configured to fix the strip seated on each of the plurality of strip seating parts, a tray movement driving part configured to slidably move the strip tray, a sensing module supported by the case and including a plurality of light-emitting diodes (LEDs) configured to emit white light for testing toward the plurality of moving strips from above the plurality of strips and a plurality of image sensors configured to detect colors of the plurality of strips, and a control part configured to control the tray movement driving part to move the strip tray.
    Type: Grant
    Filed: November 25, 2020
    Date of Patent: August 30, 2022
    Assignee: CHUNGDO PHARM Co., Ltd
    Inventors: Sung Jin Kim, Seung Jin Lee
  • Patent number: 11422106
    Abstract: Biosensors utilizing 4-acetoxyphenol are described. The biosensors typically include 4-acetoxyphenol in a substrate and utilize one or more enzymes to detect the presence of pollutant agents. Also described are related methods using the biosensors to detect the presence of pollutant agents in water such as As(III).
    Type: Grant
    Filed: February 18, 2020
    Date of Patent: August 23, 2022
    Assignee: United States Government, as represented by the Administrator of the U.S. EPA
    Inventors: Tao Li, Endalkachew Sahle-Demessie
  • Patent number: 11406299
    Abstract: A sensor comprises a microfabricated chip having a surface with one or more cavities formed thereon, the cavities including sensing components, one or more lids, each covering said surface so as to close at least one of said cavities, the lids contacting rims that delimit said cavities on said surface. Electric circuit portions join, each, a respective one of the lids, to allow the lids to be partly dissolved, electrochemically, responsive to being exposed to an electrochemical solution. In addition, masking material portions cover peripheral regions of the lids at the level of the rims, so as to seal the lids and shield such peripheral regions from said electrochemical solution, in operation. Related apparatuses and sensing methods may be provided.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: August 9, 2022
    Assignee: International Business Machines Corporation
    Inventors: Patrick Ruch, Jonas Weiss