Abstract: A method and system are provided for detection of localized hydrogen peroxide within tissue by introducing a catalase-containing material into at location of interest, positioning an ultrasound transducer over the location, and generating an ultrasound image to detect microbubbles, where the presence of microbubbles indicate the presence of localized hydrogen peroxide. The catalase-coated surface may be the inner surface of a microtube, on the surface of or incorporated within a nanosphere or microsphere, or an implantable device.

Abstract: The present invention relates to an ultrasound probe head (1), especially for HIFU treatment, comprising a treatment ultrasound transducer (2) and an imaging ultrasound transducer (3). The imaging transducer (3) comprises a shield element (4) configured such that most of the energy of ultrasound waves (10) reflected in the direction of the imaging transducer (3) are held back by said shield element (4). The shield element (4) is configured in such a way as not to interfere with the emission of the imaging ultrasound waves (7).

Abstract: An ultrasound diagnostic apparatus includes: a probe that transmits and receives ultrasound; a signal analysis unit that, when the probe scans a cross section of elevation direction of a blood vessel using ultrasound, detects a center scan line echo signal having passed through a center of the blood vessel among a plurality of scan line echo signals in the cross section of elevation direction of the blood vessel received by the probe, based on a part of each of the plurality of scan line echo signals that has a relatively small amplitude that corresponds to a reflected wave from a part of the blood vessel where blood flows; and an IMT measurement unit that computes an IMT from the center scan line echo signal. With this configuration, it is possible to provide an ultrasound diagnostic apparatus capable of performing wide-range IMT measurements with few errors even when a blood vessel seen from a body surface is not linear.

Abstract: A device is presented for use in an EEG measurement performed in the presence of a magnetic field. The device includes a wiring array for connecting an electrodes arrangement to an electroencephalogram (EEG) monitoring device. The wiring array includes sampling lines arranged to form first and second groups of sampling lines, arranged in a spaced-apart substantially parallel relationship extending along first and second axes respectively, at least some of the sampling lines being wire bundles including a plurality of wires for connecting to a corresponding plurality of electrodes of the EEG electrodes arrangement; the first and second groups of sampling lines intersect with each other to form a net structure when placed on area of measurement. The wiring array thereby enable generation of EEG data characterized by reduced motion artifact and/or reduced gradient artifact associated with the presence of the magnetic field during the EEG measurement.

Abstract: A monitoring device (1) is provided for monitoring the presence of a skin piercing vascular access device, for example a needle (4), the monitoring device comprising: a mount having an ultrasonic transmitter and an ultrasonic receiver therein; attachment means (3) for attaching the mount to a patient adjacent a vascular access point such that, in use, a vascular access device (4) entering the patient at the vascular access point, passes underneath a sensing section of the base; control electronics to monitor the signal received at the receiver, and wherein when the vascular access device is underneath said sensing section, ultrasound produced by said transmitter passes through the patient skin and is reflected by the patients body tissues and by the vascular access device (4), and when the vascular access device (4) is not underneath said sensing section, ultrasound produced by said transmitter passes through the patients skin and is reflected by the patients body tissue only, and wherein the control electron

Abstract: A method of compensating for breathing and other motions of a patient during treatment includes periodically generating internal positional data about an internal target region. The method further includes generating external positional data about external motion of the patient's body using an external sensor and generating a correlation between one or more positions of the internal target region and one or more positions of an external region using the external positional data of the external sensor and the internal positional data of the internal target region. The method further includes predicting the position of the internal target region at some later time based on the correlation model.

Abstract: A method for remotely sensing cardiac-related data of an animal subject includes transmitting a RF signal to impinge on tissue of the subject, receiving a reflected portion of the RF signal, generating baseband data, filtering baseband data (e.g., including high pass filtering), performing waveform phase position determination, performing at least one auto-correlation of the waveform phase position determined data, determining periodicity of the auto-correlated data, and (i) computing heart rate using a maximum periodicity of the periodicity, or (ii) identifying abnormalities in cardiac function, such as may be indicated by temporal variations in heart rate and/or signal amplitude corresponding to cardiac activity. Multiple bandpass filtering schemes may be employed.

Abstract: A photoacoustic imaging apparatus includes holding members configured to hold a subject, an acoustic wave conversion unit configured to receive an acoustic wave generated by irradiating the subject, which is held by the holding members, with light from a light source and convert the acoustic wave into an electric signal, a processing unit configured to generate image data from the electric signal, and an imaging unit configured to capture an optical pattern generated on a light diffusion member by emitting the light to the light diffusion member arranged on a surface of a side where the subject is irradiated with the light in the holding members where the holding members contact the subject in holding the subject, wherein the processing unit calculates light absorption coefficient distribution in the subject based on the optical pattern captured by the imaging unit and the electric signal acquired by the acoustic wave conversion unit.

Abstract: A method is disclosed for generating a time resolved series of time and energy subtracted 3D volume reconstructions, e.g., using a switched dual energy C-Arm type X-ray imaging system or a bi-plane type X-ray imaging system.

Abstract: A method and apparatus for determining the volume of a bodily structure including the steps of acquiring at least two ultrasound images, estimating the location of the perimeter of a structure of interest as viewed in cross section in each said ultrasound image, calculating the cross sectional area of such structure as so viewed, and combining the perimeter and area information from the at least two images to calculate the volume of the structure.

Abstract: A method and system for detecting and tracking multiple catheters in a fluoroscopic image sequence in an integrated central processing unit and graphics processing unit framework is disclosed. A catheter electrode model is initialized in a first frame of the fluoroscopic image sequence. The catheter landmark candidates are detected, by a graphics processing unit, in the first frame of the fluoroscopic image sequence. The catheter electrode model is tracked, by a central processing unit, and is detected by the graphics processing unit, in subsequent frames of the fluoroscopic image sequence by detecting catheter landmark candidates in the subsequent frames of the fluoroscopic image sequence using at least one trained catheter landmark detector, and outputting the catheter model tracking and landmark detection results of for each frame of the fluoroscopic image sequence.

Abstract: Embodiments for enhancing an image quality of an ultrasound image based on entropy information in an ultrasound system are disclosed. In one embodiment, an ultrasound data acquisition unit acquires multiple ultrasound data, and a processing unit forms entropy information based on the multiple ultrasound data and adaptively perform data processing for image enhancement upon the multiple ultrasound data based on the entropy information. The processing unit forms multiple ultrasound images based on the multiple ultrasound data with the data processing performed.

Abstract: A method for providing patient registration without fiducials comprises the steps of: spatially placing an ultrasound image of a patient randomly at different starting positions relative to a preoperative image; creating an independent registration corresponding to each different starting positions, by optimizing a spatial transformation between the preoperative image and the ultrasound image to provide a first batch of registrations; executing a second registration to fine-tune the alignment between the preoperative image and the ultrasound image; and concatenating the spatial transformation to obtain spatial transformation between the patient in an operating room and a corresponding preoperative image.

Abstract: Embodiments for providing an ultrasound spatial compound image are disclosed. In one embodiment, by way of non-limiting example, an ultrasound system comprises: an ultrasound data acquisition unit configured to acquire ultrasound data by transmitting and receiving ultrasound signals; and a processing unit in communication with the ultrasound data acquisition unit, the processing unit being configured to set a plurality of center lines based on a virtual common point corresponding to predetermined scan-lines, move the virtual common point along each of the center lines to set a plurality of scan-lines, form a plurality of ultrasound images corresponding to the center lines based on the ultrasound data, and perform spatial compounding upon the ultrasound images to form an ultrasound spatial compound image, wherein the ultrasound data acquisition unit is configured to acquire the ultrasound data based on the plurality of scan-lines.

Abstract: A method and system for automatic magnetic resonance (MR) volume composition and normalization is disclosed. In one embodiment, a plurality of MR volumes is received. A composite MR volume is generated from the plurality of MR volumes. Volume normalization of the composite MR volume is then performed to correct intensity inhomogeneity in the composite MR volume. The volume normalization of the composite MR volume may be performed using template MR volume or without a template MR volume.

Abstract: An ultrasonic diagnostic apparatus which can measure a time difference of motion between a plurality of sites of a cardiac muscle for the heart of a fetus is provided. On a tomographic image of the heart, a user sets a plurality of observation points. Each observation point is tracked, and a plurality of displacement waveforms representing a temporal displacement of the plurality of observation points are generated. A time difference between a plurality of representative points is calculated between the plurality of displacement waveforms. Such a time difference is displayed as a numerical value or as a graph. The representative point is a peak point, a zero-cross point, an inflection point, or the like. The plurality of observation points are set along conduction pathways in the heart for the electric signal.

Abstract: A method for quantifying the development of pathologies involving changes in volume of a body represented via an imaging technique, including normalizing gray levels by a midway technique for two images I1 and I2 representing the same scene, resulting in two normalized images I?1 and I?2; calculating a map of signed differences between the two normalized images I?1 and I?2; and performing one or more statistical tests based on the assumption of a Gaussian distribution of the gray levels for healthy tissues in the normalized images I?1 and I?2 and/or in the calculated difference map. Advantageously, results of two or more of the tests can be combined for a more specific characterization of the development.

Abstract: Systems and methods for x-ray imaging a patient's breast in combinations of dual-energy, single-energy, mammography and tomosynthesis modes that facilitate screening for and diagnosis of breast abnormalities, particularly breast abnormalities characterized by abnormal vascularity.

Abstract: A method and system for tracking an ablation catheter and a circumferential mapping catheter in a fluoroscopic image sequence is disclosed. Catheter electrode models for the ablation catheter and the circumferential mapping catheter are initialized in a first frame of a fluoroscopic image sequence based on user inputs. The catheter electrode models for the ablation catheter and the circumferential mapping catheter are then tracked in each remaining frame of the fluoroscopic image sequence. In each remaining frame, candidates of catheter landmarks such as the catheter tip, electrodes and body points are detected for the ablation catheter and the circumferential mapping catheter, tracking hypotheses for the catheter electrode models are generated, and for each of the ablation catheter and the circumferential mapping catheter, the catheter electrode model having the highest probability score is selected from the generated tracking hypotheses.

Abstract: A method and system for detecting and tracking coronary sinus (CS) catheter electrodes in a fluoroscopic image sequence is disclosed. An electrode model is initialized in a first frame of the fluoroscopic image sequence based on input locations of CS sinus catheter electrodes in the first frame. The electrode model is tracked in subsequent frames of the fluoroscopic image sequence by detecting electrode position candidates in the subsequent frames of the fluoroscopic image sequence using at least one trained electrode detector, generating electrode model candidates in the subsequent frames based on the detected electrode position candidates, calculating a probability score for each of the electrode model candidates, and selecting an electrode model candidate based on the probability score.