Abstract: Embodiments of the present invention are directed to devices, systems and methods adapted for implementing intermittent displacement of blood to mitigate peripheral nerve neuropathy such as that induced by chemotherapeutic agents (i.e., chemotherapy-induced neuropathy (CIN)) that are administered to a patient. Such devices, systems and methods advantageously provide for precise, uniform and controlled blood flow occluding (and optionally blood displacing) compression along irregular surfaces of an appendage of a patient. Such precise, uniform and controlled blood occluding compression is imparted upon the epidermal and dermis skin layers within the aforementioned areas of a patient's extremities to decrease the time that free nerve endings located in the epidermal and encapsulated nerve endings located in the dermis skin layers are exposed to nerve damaging chemotherapy chemicals, thereby substantially decreasing CIN caused by prolonged exposure to such chemicals.

Abstract: A fluid extraction implantable system shaped and sized to be implanted in a patient, including: a fluid extraction chamber having a flat and thin shape connected to a draining tube and including at least one external flat surface, wherein the at least one external flat surface is configured to be attached to a tissue surface when a negative pressure is applied on the draining tube, wherein the chamber extracts fluids from the tissue by applying the negative pressure through the flat surface on the attached tissue surface.

Abstract: A modular glaucoma implant for the treatment of glaucoma is described. Embodiments disclosed describe a glaucoma treatment device including an elongated fixation stent that allows aqueous humor to flow from the anterior chamber of the eye to the Schlemm's Canal when implanted. One or more drainage tubes can be inserted into the fixation stent such that the drainage tubes allow aqueous humor to flow from the anterior chamber of the eye to the suprachoroidal space. Surgeons can opt to add as many drainage tubes as desired based on the needed aqueous humor outflow rate.

Abstract: An oxygenator with a housing wall, which delimits a housing space with a blood inlet and a blood outlet, a gas inlet and a gas outlet, has a heating element which is arranged in the oxygenator between blood inlet and blood outlet in order to control the temperature of blood flowing through the housing space. For this purpose, the oxygenator has a radiation source and a receiver. The radiation source can be an infrared emitter and the receiver a matte-black surface, or the radiation source is an induction coil and the receiver has a material capable of induction. In a method for regulating the heat output on a heating element of an oxygenator, the through-flow of the blood through the oxygenator and the power of a pump acting on the through-flow are measured, and the heating power is adjusted in accordance therewith.

Abstract: Devices are provided with a bridge made of a biocompatible material that surrounds a neck region of an encapsulated shunt. In one embodiment, the bridge is configured to maintain an outer diameter while the diameter of the neck region is reduced or increased in vivo to adjust the fluid flow rate through the device. The bridge may have an outer diameter that is configured to be placed within an enlarged septal hole. Methods for adjusting the flow of fluid and methods for the manufacture of such devices are also provided.

Abstract: The present invention provides a cerebrospinal fluid shunt system that monitors the intracranial pressures over a portion of a monitoring cycle to calculate short intervals of drainage for every monitoring cycle necessary to produce the desired pressure correction. The system operates to significantly reduce the time during which draining occurs allowing tissue surrounding the catheter to rebound from the catheter holes returning to its normal position for a sufficient amount of time to recover its normal shape.

Abstract: The invention relates to a vacuum treatment array having at least one open-pored contact element, by way of which a negative pressure and/or suction can be generated in a body cavity, wherein the open-pored contact element is configured, at least in sections, in the manner of a tube, having an outer and/or inner boundary surface rotating around a tube axis, at least in part.

Abstract: A system for increasing blood flow through a user's limb during a blood collection procedure includes an inflatable cuff that is worm around the user's limb. A pump and a deflation valve are in fluid communication with the inflatable cuff. A heating element and a temperature sensor are attached to the inflatable cuff. The system also includes a motion sensor. A controller is in communication with the pump, the deflation valve, the heating element and the temperature and motion sensors and detects a blood pressure or blood flow of the user, controls inflation and deflation of the inflatable cuff and controls energization of the heating element based on data from the motion sensor and the temperature sensor.

Abstract: An oxygenator includes a housing having a blood inlet and a blood outlet, the blood inlet extending into an interior of the housing. A heat exchanger is disposed within the housing, and is coupled, at an inlet end, to a heat-exchange fluid inlet. A gas exchanger also is disposed within the housing, and includes a bundle of gas-exchange fibers coupled, at a gas outlet end, to a gas-exchange fluid outlet. The oxygenator includes at least one insulator configured to thermally insulate at least the gas outlet end of the bundle of gas-exchange fibers.

Abstract: In one example embodiment, an apparatus may include a panel with integrated fluid channels, wherein the panel and the fluid channel consist only of surfaces that can be manufactured with a straight-pull mold. A port may also be integrated into the panel to facilitate coupling the fluid channel to pneumatic components in an assembly. A seal may be secured to the panel over the fluid channel to form an integrated fluid conductor. The seal is preferably an adhesive label that can also be used for product labeling. Such an apparatus may be used in a control unit of a therapy system, employing several integrated fluid conductors. A method of manufacturing may include molding a panel, wherein the mold forms a channel integral to the panel. The panel and the channel preferably consist of surfaces that can be molded with a straight-pull mold.

Abstract: In certain embodiments, a vial access device for removing liquid contents from a vial includes a piercing member extending from a base of an insertion member and a reservoir. The reservoir can be contained within the piercing member and the insertion member, such that the reservoir is introduced to the vial when piercing member is inserted into the vial. The piercing member is adapted to be opened inside the vial to expose the reservoir to the contents inside the vial. A locking mechanism can prevent the piercing member from being inserted into the vial unless the vial access device is fully coupled to the vial and/or prevent the piercing member from being withdrawn from the vial without uncoupling the vial access device from the vial.

Abstract: A hemodialysis system includes: a hemodialysis machine configured to provide hemodialysis treatment to a patient, wherein the hemodialysis treatment includes circulating extracorporeal blood of the patient through an extracorporeal blood circuit; a first oxygen saturation sensor device configured to measure oxygen saturation corresponding to the extracorporeal blood of the patient in the extracorporeal blood circuit; a second oxygen saturation sensor device configured to measure oxygen saturation corresponding to blood flowing within the patient; and at least one controller configured to determine one or more oxygen saturation phase shift (OSPS) values or one or more transcutaneous travel time values corresponding to the patient based on oxygen saturation measurements from the first oxygen saturation sensor device and the second oxygen saturation sensor device.

Abstract: The present disclosure discloses an integrated membrane oxygenator including an oxygenator and a filter attached to the oxygenator. The oxygenator may include an upper cover, a lower cover, a shell, and an oxygenation structure. Two ends of the filter may be respectively connected with the upper cover and the lower cover. The oxygenation structure may include a mandrel, an oxygen pressure membrane, and a temperature-changing membrane arranged inside the shell. The filter may include a filter shell, a diversion structure, and a filter screen arranged inside the filter shell. An inlet of the filter shell may be connected with a blood outlet on the lower cover of the oxygenator, and blood oxygenated by the oxygenator may directly enter the filter for filtration.

Abstract: A catheter comprising an elongated member having a distal end and a proximal end. The proximal end defines a drainage inlet extending from an external wall of the elongated member into the elongated member. The elongated member defines a first lumen that connects the drainage inlet with a drainage outlet defined by the distal end. The catheter also includes an inflatable retention balloon defined by the external wall of the elongated member and located between the drainage inlet and the drainage outlet. The catheter further includes a fluid inlet valve that protrudes from the elongated member and defines a second lumen that extends from the fluid inlet valve through the elongated member and to the inflatable retention balloon. The catheter additionally includes a secondary balloon that protrudes from the elongated member, the elongated member defining a third lumen that extends from the inflatable retention balloon to the secondary balloon.

Abstract: A flexible, polymer sleeve is provided that is everted into a body passageway in such a manner as to exert minimal rubbing friction on the internal walls of such passageway. The sleeve is housed within a tube assembly comprising a posterior tube that telescopingly slides into an insertion tube. The sleeve everts over the insertion tube, upon forward pressure applied thereon, as it extends forward into a body passageway, and consequently, causes the posterior tube to retract into the insertion tube. Multiple tubes can be telescoped to support the polymer sleeve and to keep a passageway open for the expelling of urine or body fluids, the insertion of tools, sanitation/antibacterial substances, or for the flow of liquids through the sleeve. The insertion tube can be locked in reference to the sleeve to prevent unintended removal of catheter assembly. Sleeve and tubing are removed by reversing the insertion and eversion movements.

Abstract: The embodiments of the present disclosure may provide a membrane oxygenator with a built-in filter, including an upper cover, a lower cover, a shell and an oxygenation structure, wherein two ends of the shell may be respectively connected to the upper cover and the lower cover, and the oxygenation structure may be disposed in the shell, including a mandrel, a filter screen, an oxygen pressure membrane, and a temperature-changing membrane in turn from a center to an outside. The blood may flow in from an upper blood inlet of the membrane oxygenator, traverse the temperature-changing membrane, oxygen pressure membrane and filter screen in turn, and then flow out from a blood outlet under the mandrel. During a process of traversing, a flow rate of the blood may gradually slow down, and the blood may fully contact the oxygen pressure membrane and the filter screen.

Abstract: A finger sleeve for cleaning or drying the outer human ear.

Abstract: A hand-held aspiration device is provided which has a relatively small suction volume along a suction path to improve responsiveness of the aspiration device when the device is activated. The device may be manually powered and may be provided without electronic controls. The device has a suction path which may be purged into a disposal enclosure to reduce the volume of material under the influence of the suction pressure during the procedure. The suction source may also be part of the hand-held unit to further reduce the suction path and suction volume.

Abstract: A manifold for a medical/surgical waste collection system. An outlet opening and a fitting are in fluid communication with a manifold volume within a housing. The fitting receives a suction line. A filter element with porous features is disposed within the housing such that a fluid communication path is established across the filter element. The porous features trap material entrained within the fluid. A material collection volume is at least partially distal to and below a bottom of the filter element. As the fluid and the material is drawn through the fluid communication path, the material collects within the material collection volume. A flow diverter may be positioned within the housing for directing the material towards the material collection volume. The material collection volume may be at least partially defined by a tissue trap removably coupled to the housing.

Abstract: A wound therapy apparatus is disclosed herein. In various aspects, the wound therapy apparatus may include a distal layer to contact a wound bed, the distal layer comprised of silicone, and fenestrations disposed about the distal layer pass between a distal side of the distal layer and a proximal side of the distal layer to communicate between the distal side and the proximal side. A pad may cooperate with the proximal side of the distal layer to receive exudate communicated through the distal layer from the wound bed via the fenestrations, in various aspects. Various materials including medicament(s) may be communicated to the wound bed through the distal layer via the fenestrations, in various aspects. A structural member may be included in various aspects to secure the distal layer and pad to a skin surface, in various aspects. Methods of use of the wound therapy apparatus are disclosed herein. This Abstract is presented to meet requirements of 37 C.F.R. § 1.