Abstract: A collapsible sample collection device with a novel, collapsible 3D capture open affinity net dispersed throughout the volume of the container, said net with tethered affinity moieties, is designed to address the need for low-cost, simple harvesting and concentration of diagnostic analytes that generally does not require any ancillary equipment. The collection device generally permits analytes of interest to be efficiently harvested from body fluid samples, in one step, concentrated, collapsed into a flat mailing size, and protected from degradation without the need for traditional cold chain technologies. The concentration factor will increase sensitivity by several orders of magnitude when coupled with any type of downstream analyte measurement, including point of care testing. The collection device, in various embodiments, obviates the need for handling transport or storage of the fluid portion of the body fluid sample (e.g. blood, urine, saliva, etc.

Abstract: Method and system for monitoring an internal electrical impedance of a biological object including Internal Thoracic Impedance (ITI) comprising placing two arrays of electrodes on opposite sides of the biological object, wherein each of said two arrays comprise three equally spaced electrodes; imposing an alternating electrical current between pairs of the electrodes and obtaining voltage signals representative of a voltage drop thereon, calculating two values of internal electrical impedance of the biological object corresponding to the uttermost electrodes of said two arrays of electrodes placed on the opposite sides of the biological object.

Abstract: This disclosure relates to a sensor-based monitor for movements of workers. Multiple inertial sensors are attached to different body parts of the workers. A mobile device application receives the inertial movement data from the sensors and identify movement patterns by applying a trained machine learning model to the inertial movement data. The application then determine for each movement pattern an amount of time that movement pattern occurred and accessing a database to retrieve stored data on an association between the identified movement patterns and injuries. The application calculates a risk value indicative of a risk of injury of the worker as a result of performing the identified movement pattern for the determined amount of time and produces a report detailing the risk value for each of multiple risk categories.

Abstract: A scratching detection system includes a sensor and processor. The sensor is configured to detect acceleration corresponding to movement of a person's hand and is configured to output a first signal including a detected value corresponding to the acceleration in a first cycle. The processor is configured to acquire the first signal and to detect a scratching behavior of the person in a second cycle based on a plurality of parameters. The second cycle includes a plurality of the first cycles. The plurality of parameters includes a first occurrence count and a first consecutive count. The first occurrence count is a number of times an absolute value of the detected value exceeds a threshold value in the second cycle. The first consecutive count is a maximum value of a number of times that the absolute value of the detected value consecutively exceeds the threshold value in the second cycle.

Abstract: A cognitive function evaluation device includes: an instruction unit that instructs quick pronunciation of pseudoword in which a predetermined syllable is repeated; an obtainment unit that obtains voice data indicating a voice of an evaluatee who has received an instruction; a calculation unit that calculates a feature from the voice data obtained by the obtainment unit; an evaluation unit that evaluates a cognitive function of the evaluatee from the feature calculated by the calculation unit; and an output unit that outputs a result of the evaluation by the evaluation unit.

Abstract: Devices, systems, and methods for monitoring musculoskeletal (MSK) health conditions of an individual, including joint flexibility, strength, and endurance as part of their overall care plan are described here. The overall system includes: a sensor that can be worn anywhere on the human body, an engaging app on a mobile-computing device, and software-based analytics and care management engine running on a cloud-computing infrastructure. The sensor is tuned to measure any human joint movement in any direction or axis as well as elevation and temperature. Methods performed by the various devices and systems and how it improves MSK health are provided.

Abstract: Continuous temperature monitors can be used to collect frequent temperature data over large periods of time. A machine learning system trained with collected temperature data can be used to predict future temperature data for patients. Such predictions can be clinically beneficial for disease states in which fever can be fatal, particularly for those fevers having fast onset. For example, patients undergoing chimeric antigen receptor T-cell (CAR-T) therapy may suffer fevers caused by cytokine release syndrome (CRS). Accordingly, a continuous temperature monitor is used to collect temperature data from CAR-T patients with high risk of CRS (or like patients with high fever risk), and the collected temperature data processed by a machine learning system to predict the patient's future temperature profiles. Results of analysis of the predicted temperature profiles may then be provided to the patient and/or clinician.

Abstract: An exit prediction system receives movement data, divides the movement data into segments of time, extracts features from each segment of time, and determines a pattern of movement from the extracted features. A patient exit from a patient support apparatus is predicted based on the determined pattern of movement.

Abstract: A cognitive function evaluation method in a cognitive function evaluation device that evaluates a cognitive function based on a walking motion of a subject includes: acquiring walking data related to walking of the subject; detecting, from the walking data, at least one of an angle of an ankle joint of one foot and an angle of a knee joint of one leg of the subject; and determining a cognitive function level of the subject using at least one of the angle of the ankle joint and the angle of the knee joint.

Abstract: In one embodiment, a temperature sensor system includes a sensor assembly with a temperature sensing portion configured to generate a first signal based upon a temperature of body proximate a surface portion of the temperature sensing portion, and a thermoelectric generator portion configured to receive heat flow from the body through the temperature sensing portion and to generate a second signal based upon the heat flow. A control unit is operably connected to the sensor assembly and a memory and configured to execute program instructions stored in the memory to calculate and output a corrected temperature based upon the first signal, the second signal, and at least one correction factor stored in the memory. The at least one correcting factor is determined based upon at least one of a thermal conductivity of the sensor assembly, a size of the sensor assembly, and an aspect ratio of the sensor assembly.

Abstract: A system for accessing a patient's uterine cavity and detecting perforations in the uterus includes an elongated probe having a flow channel extending to a terminal outlet in a distal region of the probe. A fluid source is coupled to the flow channel, and a seal on the probe is positionable in an endocervical canal. The probe may be trans-cervical inserted into the uterine cavity, and a fluid may be introduced through the channel to flow outwardly from the terminal outlet into the uterine cavity. A parameter of said fluid flow is monitored to detect a perforation in the uterus.

Abstract: A cognitive function evaluation device includes: an obtainment unit configured to obtain speech data indicating speech uttered by a subject; a calculation unit configured to extract a plurality of vowels from the speech data obtained by the obtainment unit, and calculate, for each of the plurality of vowels, a feature value based on a frequency and an amplitude of at least one formant obtained from a spectrum of the vowel; an evaluation unit configured to evaluate a cognitive function of the subject from the feature value calculated by the calculation unit; and an output unit configured to output an evaluation result of the evaluation unit.

Abstract: Automated modular physical health testing systems and associated devices and methods are disclosed herein. A modular system configured in accordance with embodiments of the present technology can include, for example, a housing, a communications hub, and a plurality of physical health testing devices. The housing integrates the communications hub and stores the plurality of physical health testing devices. The physical health testing devices are in wired and/or wireless communication with the communications hub. Each physical health testing device is configured to generate physical health data of a user and to transmit generated physical health data to the communication hub and/or a user's mobile device. The modular physical health testing system provides an automated physical exam that can be performed at user's homes or other convenient locations.

Abstract: Methods and systems are provided for measuring anatomical dimensions from a single two-dimensional (2D) digital image. The digital image is taken from the front/anterior view using a mobile, handheld communication device. The linear measurements are used to estimate the body volume of the individual. Total body density is calculated from estimated body volume and body weight. Body composition (fat mass and fat-free mass) of the individual is derived from density using known mathematical conversion formulas. A method for estimating body composition analysis is provided.

Abstract: Apparatus for performing impedance measurements on a subject. The apparatus includes a first processing system for determining an impedance measurement procedure and determining instructions corresponding to the measurement procedure. A second processing system is provided for receiving the instructions, using the instructions to generate control signals, with the control signals being used to apply one or more signals to the subject. The second processing system then receives first data indicative of the one or more signals applied to the subject, second data indicative of one or more signals measured across the subject and performs at least preliminary processing of the first and second data to thereby allow impedance values to be determined.

Abstract: A method for monitoring the progress of post-operative ambulation is disclosed. A patient after a surgical procedure such as an operation is provided with an ambulatory routine. The ambulatory routine is monitored using a wearable biosensor device operable to track steps of the patient. The steps of the patient in following the ambulatory routine are recorded. The ambulation data is displayed on a periodic basis to provide feedback to both the patient and health care professionals.

Abstract: A telescoping assembly such as an endobronchial ultrasound needle (EBUS) assembly includes a motor coupled to a biopsy needle within a telescoping housing to rotate (such as to oscillate) the needle during tissue harvest to improve harvesting.

Abstract: An apparatus includes a pre-sample reservoir, a diversion mechanism, and a flow metering mechanism. The diversion mechanism has an inlet port couplable to a lumen-defining device to receive bodily-fluids from a patient, a first outlet port fluidically couplable to the pre-sample reservoir, and a second outlet port fluidically couplable to a sample reservoir. The diversion mechanism defines a first fluid flow path and a second flow path that are configured to place the first outlet port and the second outlet port, respectively, in fluid communication with the inlet port. The flow metering mechanism is configured to meter a flow of a predetermined volume of bodily-fluid through the first fluid flow path into the pre-sample reservoir, to meter a flow of a second volume of bodily-fluid through the second fluid flow path into the sample reservoir, and to display a volumetric indicator associated with the predetermined volume and the second volume.

Abstract: The present disclosure provides computer-implemented methods, systems, and devices for improved skin temperature monitoring. Accurate estimates of skin and ambient temperature are generated based on determinations and comparisons of skin and internal device temperature sensor measurements contained on or within example devices. The estimates of skin and ambient temperature measurements facilitate monitoring skin and core temperature changes, detecting physiological events of a wearer of example devices, and determining when skin temperature changes are environmentally or physiologically induced.

Abstract: A cable for use with a pressure monitoring catheter, the catheter including an inflatable balloon forming a fluid chamber for pressure measurement. The cable has a first end operably connectable to the catheter, a second end operably connectable to a monitor providing pressure displays, and a printed circuit. The cable includes one or both of the filter system to enable collection and analysis of data and an adjustment feature to adjust pressure values in response to patient movement.