Patents Examined by Bernard Dentz
  • Patent number: 8492565
    Abstract: To provide a process for producing BPDA whereby high productivity is attained while high purity is maintained. A process for producing biphenyltetracarboxylic acid dianhydride, which comprises heating biphenyltetracarboxylic acid to produce biphenyltetracarboxylic acid dianhydride, characterized in that the heating is carried out at a pressure of from 1×102 Pa to 1.1×105 Pa to a maximum temperature in a range of from 210° C. to 250° C. in such a manner that the temperature rising rate is higher than 50° C./hr for a period of at least ¼ of the time for the temperature rise from 60° C. to 210° C., and the temperature is maintained to be from 150° C. to 250° C. for from 0.5 to 10 hours.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: July 23, 2013
    Assignee: Mitsubishi Chemical Corporation
    Inventors: Hiroshi Mikami, Makoto Nitta, Naoki Noguchi
  • Patent number: 8480764
    Abstract: Process for converting cellulose and hemicellulose into dimethyl furan, hydrolysing first cellulose in a mixture of N alkyl imidazolium chloride, hydrochloric acid 37% and an alcohol, to produce an acetal of glucose, making the dehydration to an acetal of hydroxymethyl furfural, extracting and making the hydrogenation of this acetal and distilling to produce dimethyl furan.
    Type: Grant
    Filed: February 11, 2012
    Date of Patent: July 9, 2013
    Inventor: Pedro Manuel Brito da Silva Correia
  • Patent number: 8481766
    Abstract: Methods for the epoxidation of alkenes are provided. The methods include the steps of exposing the alkene to a two-component catalyst system in an aqueous solution in the presence of carbon monoxide and molecular oxygen under conditions in which the alkene is epoxidized. The two-component catalyst system comprises a first catalyst that generates peroxides or peroxy intermediates during oxidation of CO with molecular oxygen and a second catalyst that catalyzes the epoxidation of the alkene using the peroxides or peroxy intermediates. A catalyst system composed of particles of suspended gold and titanium silicalite is one example of a suitable two-component catalyst system.
    Type: Grant
    Filed: November 10, 2010
    Date of Patent: July 9, 2013
    Assignee: Northwestern University
    Inventors: Mayfair C. Kung, Harold H. Kung, Jian Jiang
  • Patent number: 8476464
    Abstract: Embodiments of the present disclosure provide processes, columns, and systems for removing acetaldehyde from alkylene oxide in a feed stream and for providing an alkylene oxide-water stream that can be directly transferred to a glycol reaction process. The alkylene oxide purification column includes a first section to convert a feed stream into a gas phase portion and a liquid phase portion and a second section located in the column above the first section to separate alkylene oxide from the acetaldehyde, water, and other impurities that enter the second section from the first section.
    Type: Grant
    Filed: August 6, 2012
    Date of Patent: July 2, 2013
    Assignee: Dow Technology Investments LLC
    Inventors: John F. Szul, James H. McCain, Floyd L. Pfeffer, Harvey E. Andresen, Phillip R. Fairchild, Kent E. Newman
  • Patent number: 8471044
    Abstract: Crystalline epigallocatechin-3-gallate compositions and methods of use.
    Type: Grant
    Filed: June 6, 2008
    Date of Patent: June 25, 2013
    Assignee: University of South Florida
    Inventors: Michael Zaworotko, Sheshanka Kesani
  • Patent number: 8471043
    Abstract: The present invention relates to novel platensimycin derivatives, their intermediates and preparing methods of the same. Platensimycin is known as an effective antibiotic material having a broad antimicrobial spectrum and its derivatives are also expected to be effective antibiotic candidates. The present invention also relates to a novel preparing method of platensimycin. The intermediates used for the production of platensimycin and its derivatives of the present invention are tricyclo ketone derivatives and tetracyclo derivatives. Tetracyclo derivatives are prepared from tricyclo ketone derivatives prepared by carbonyl ylide [3+2] cycloaddition of dia-zoketone derivative.
    Type: Grant
    Filed: March 31, 2009
    Date of Patent: June 25, 2013
    Assignee: SNU R&DB Foundation
    Inventors: Eun Lee, Ki Po Jang, Chan Hyuk Kim, Seong Wook Na, Dong Seok Jang
  • Patent number: 8461364
    Abstract: This invention provides, among other things, polymorphs of the hydrochloride salt of (S)-3-aminomethyl-7-(3-hydroxy-propoxy)-3H-benzo[c][1,2]oxaborol-1-ol.
    Type: Grant
    Filed: December 17, 2009
    Date of Patent: June 11, 2013
    Assignees: GlaxoSmithKline LLC, Anacor Pharmaceuticals, Inc.
    Inventors: Conrad Wheeler, Dan Todd, Pingyun Chen, Beth A. Norton
  • Patent number: 8461360
    Abstract: A process for the production of ?-mangostin comprising the steps of preparing O-methyl ?-mangostin preferably from plants, subjecting the pure or partially pure O-methylated ?-mangostin to demethylation reaction procedure followed by purification of the said demethylated product to obtain pure ?-mangostin.
    Type: Grant
    Filed: July 17, 2008
    Date of Patent: June 11, 2013
    Assignee: Laila Nutraceuticals
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Trimurtulu Golakoti, Venkateswarlu Somepalli, Kiran Bhupathiraju
  • Patent number: 8461359
    Abstract: The invention relates to a method for preparing 1,6:2,3-dianhydro-?-D-mannopyranose and is characterized in that it includes a step of cyclizing the compound B, where R is an activating agent, in the presence of a base selected from among ammonium hydroxides and mineral bases.
    Type: Grant
    Filed: September 15, 2009
    Date of Patent: June 11, 2013
    Assignee: Sanofi
    Inventors: Laurent Bouvenot, Paul Cruciani, Denis Largeau, Jean-Claude Rovera
  • Patent number: 8461362
    Abstract: Tocopheryl succinate derivatives according to formula I: are described. These compounds increase the activity of protein phosphatase 2A, can be included in pharmaceutical compositions, and can be used for the treatment of androgen receptor-dependent cancers such as prostate cancer.
    Type: Grant
    Filed: April 13, 2010
    Date of Patent: June 11, 2013
    Assignee: The Ohio State University Research Foundation
    Inventors: Ching-Shih Chen, Dasheng Wang, Samuel K. Kulp
  • Patent number: 8445704
    Abstract: A process is disclosed for converting polysaccharides to platform chemicals. The process comprises dissolving the polysaccharides in a inorganic molten salt hydrate, converting the polysaccharides to monosaccharides, and converting the monosaccharides to platform chemicals that are easily separable from the inorganic molten salt hydrate. Preferably the polysaccharides are provided in the form of a biomass, more preferably a ligno-cellulosic biomass.
    Type: Grant
    Filed: September 13, 2010
    Date of Patent: May 21, 2013
    Assignee: BIOeCON International Holding N.V.
    Inventors: Paul O'Connor, Rafael Menegassi De Almeida, Jacob A. Moulijn, Michiel Makkee, Sjoerd Daamen
  • Patent number: 8440845
    Abstract: A process is disclosed for converting a polysaccharide-containing biomass material to platform chemicals. The process comprises dissolving the polysaccharides in an inorganic molten salt hydrate, converting the polysaccharides to monosaccharides, and converting the monosaccharides to derivatized (di)anhydro sugars that are easily separable from the inorganic molten salt hydrate. The derivatized (di)anhydro sugars are useful as fuel additives and fuel substitutes.
    Type: Grant
    Filed: September 19, 2011
    Date of Patent: May 14, 2013
    Assignee: BIOeCON International Holding N.V.
    Inventors: Michiel Makkee, Jacob Adriaan Moulijn, Rafael Menegassi De Almeida, Paul O'Connor
  • Patent number: 8440862
    Abstract: The present invention is directed to a process for preparing ?-amino-?-hydroxycarboxamides. The process works with epoxycarboxamides of the formula 2 which are reacted with ammonia or other amines.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: May 14, 2013
    Assignee: Evonik Degussa GmbH
    Inventor: Günter Knaup
  • Patent number: 8425960
    Abstract: The present invention relates to a coloring food composition containing modified colorings of the anthocyanin family and to a process for the bathochromic modification of these colorings. This coloring composition can be used as additive or ingredient in food preparations.
    Type: Grant
    Filed: March 17, 2008
    Date of Patent: April 23, 2013
    Assignee: Diana Naturals
    Inventors: Claude Inisan, Matthieu Besnard, Cecile Bahu, Denis Megard
  • Patent number: 8420440
    Abstract: A compound of Formula (I): wherein X, A, Y, Z, R1, R2, Ar, n and m are as described herein. The compound of Formula (I) is useful as part of a semiconducting composition to be deposited upon a surface. When heated, the compound of Formula (I) is converted to a crystalline semiconductor with high mobility.
    Type: Grant
    Filed: February 10, 2011
    Date of Patent: April 16, 2013
    Assignee: Xerox Corporation
    Inventors: Yiliang Wu, Anthony James Wigglesworth, Ping Liu, Nan-Xing Hu
  • Patent number: 8415489
    Abstract: The invention provides compounds that are A-type procyanidins. The compounds can be prepared by reacting flavylium salts with catechins or analogs thereof, for example, under anhydrous conditions in alcohol.
    Type: Grant
    Filed: November 9, 2011
    Date of Patent: April 9, 2013
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: George A. Kraus, Yi Yuan
  • Patent number: 8410292
    Abstract: Disclosed are englerins and derivatives (I) thereof useful in the treatment of a number of cancers, particularly renal cancer, as well as pharmaceutical compositions and method of treating a patient with the use of these derivatives. The englerins, for example Englerin A and Englerin B, can be isolated from the plant Phyllanthus engleri or produced by synthetic methods. An example of the englerin derivative is 2?-chloroenglerin A, which has the structure (II), wherein double bond ‘a’ is E, Z, or a mixture of E and Z.
    Type: Grant
    Filed: December 30, 2008
    Date of Patent: April 2, 2013
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: John A. Beutler, Ranjala Ratnayake, David Covell, Tanya R. Johnson
  • Patent number: 8410293
    Abstract: The present invention relates to a process for the preparation of cyclic enol ethers.
    Type: Grant
    Filed: June 28, 2012
    Date of Patent: April 2, 2013
    Assignee: BASF SE
    Inventors: Klaus Ebel, Bernhard Brunner, Christoph Stock, Ralf Pelzer
  • Patent number: 8404190
    Abstract: A hydrocarbon-containing gas is mixed with an oxygen-containing gas in a gas mixer in the presence of a water mist. The water mist surrounds and contacts entrained particles in either the oxygen-containing gas stream or the hydrocarbon-containing gas stream. The water acts to suppress and prevent ignition of the hydrocarbon gas in the mixer by serving as a sink for heat created by energetic collisions between such particles and structures within the gas mixer. The water mist also acts to quench ignition caused by such collisions. The water mist can be introduced into the gas mixer in a number of different configurations, including via nozzles injecting a mist into a hydrocarbon gas manifold or an oxygen gas manifold, nozzles placed within the gas mixer adjacent to ends of the oxygen supply pipes, and nozzles placed coaxially within the oxygen supply pipes in the gas mixer.
    Type: Grant
    Filed: November 7, 2008
    Date of Patent: March 26, 2013
    Assignee: Dow Technology Investments LLC
    Inventors: Harvey E. Andresen, Christopher P. Christenson, Charles W. Lipp, John R. Mayer, Thomas J. Kling, Victor R. Fey, Laurence G. Britton, Michael J. Rangitsch, Michael L. Hutchison
  • Patent number: 8404088
    Abstract: The present invention provides a new strategies for the synthesis of compounds of the rocaglamide family and related natural products. The synthetic approach generally involves photochemical generation of an oxidopyrylium species from a 3-hydroxychromone derivative followed by an enantioselective 1,3-dipolar cycloaddition of the oxidopyrylium species to a dipolarophile in the presence of a TADDOL derivative. This approach can be used for the formation of adducts containing an aglain core structure. Methods of the conversion of aglain core structures to aglain, rocaglamide and forbaglin ring systems are also provided. The present invention also relates to the use of rocaglamide/aglain/forbaglin derivatives for the manufacture of medicaments for use in the treatment of cancer or cancerous conditions, disorders associated with cellular hyperproliferation, or NF-?B-dependent conditions.
    Type: Grant
    Filed: March 19, 2012
    Date of Patent: March 26, 2013
    Assignee: Trustees of Boston University
    Inventors: John A. Porco, Jr., Baudouin Gerard