Abstract: A system and method for non-invasive and continuous measurement of cardiac chamber volume and derivative parameters including stroke volume, cardiac output and ejection fraction comprising an ultrawideband radar system having a transmitting and receiving antenna for applying ultrawideband radio signals to a target area of a subject's anatomy wherein the receiving antenna collects and transmits signal returns from the target area which are then delivered to a data processing unit, such as an integrated processor or PDA, having software and hardware used to process the signal returns to produce a value for cardiac stroke volume and changes in cardiac stroke volume supporting multiple diagnostic requirements for emergency response and medical personnel whether located in the battlefield, at a disaster site or at a hospital or other treatment facility.

Abstract: The invention is an interface device and system for establishing an operating interface between an injector device and diagnostic imaging equipment. In one embodiment, the interface device may permit an operator to concurrently operate and control the injector device and the imaging equipment. The interface device may permit the injector system and the imaging system to communicate information regarding their current and future operational status with each other. The interface device may be used to synchronize the operation of the imaging equipment and the injector device. In one embodiment, the injector device and the imaging equipment may be able to communicate with each other directly or through the interface device via a communications protocol comprising binary logic signals. The binary logic signals may comprise one or more of a low strength signal, a high strength signal, an oscillating signal that oscillates between low and high signal strength, and combinations thereof.

Abstract: A system and method are provided for delivering a medical device on a catheter to a selected position within a lumen of the body. A medical positioning system (MPS) acquires MPS data for points within the lumen using an MPS sensor on the catheter. Each of the points is associated with a three-dimensional coordinate system and an activity state of an organ of the patient. A user interface receives position data for the selected position. The position date is associated with an MPS representation associated with one of the points. A processor determines a plurality of temporal three-dimensional trajectory representations based on the MPS data and corresponding to the respective activity states of the organ. The processor superimposes the temporal three-dimensional trajectory representations on a two-dimensional image according to the activity states of the organ thereby enabling an operator to visually navigate the medical device toward the selected position.

Abstract: Systems and methods are described for acquiring, processing, and presenting boundaries of a cavity-tissue interface within a region-of-interest in an ultrasound image based upon the strength of signals of ultrasound echoes returning from structures within the region-of-interest. The segmentation of boundaries of cavity shapes occupying the region-of-interest utilizes cost function analysis of pixel sets occupying the cavity-tissue interface. The segmented shapes are further image processed to determine areas and volumes of the organ or structure containing the cavity within the region-of-interest.

Abstract: A method is disclosed for operating a hybrid medical imaging unit including a first imaging device of relatively high spatial resolution and a second nuclear medicine imaging device of relatively high sensitivity that respectively acquire imaging measurement signals from a common examination volume. In at least one embodiment, the method includes determining the duration of the measurement signal acquisition of one imaging device as a function of the duration of the measurement signal acquisition of the other imaging device, which is defined by the occurrence of a specific truncation criterion.

Abstract: The present invention provides procedures and systems that use a closed-loop approach for directing ultrasound energy at a clot while monitoring blood flow and/or liquification of the clot tissue so as to allow automated and/or manual adjustments to various treatment parameters.

Abstract: Radioimaging methods, devices and radiopharmaceuticals therefor.

Abstract: A focused ultrasound system includes an ultrasound transducer device forming an opening, and having a plurality of transducer elements positioned at least partially around the opening. A focused ultrasound system includes a structure having a first end for allowing an object to be inserted and a second end for allowing the object to exit, and a plurality of transducer elements coupled to the structure, the transducer elements located relative to each other in a formation that at least partially define an opening, wherein the transducer elements are configured to emit acoustic energy that converges at a focal zone.

Abstract: A multi-focus probe that includes a motor communicatively coupled with a lead screw and configured to turn the lead screw about a lengthwise axis of the lead screw, wherein the lead screw includes a length having threads. The probe also includes a lead-screw nut positioned about the lead screw such that the lead-screw nut engages the threads and such that the lead-screw nut and the lead screw can move relative to one another via the threads, a transducer configured to move vertically with the lead screw, and an enclosure surrounding the transducer, wherein the enclosure includes a probe face configured to hold fluid and engage a wave emission target such that waves from the transducer can enter the target.

Abstract: A system (10) includes electromagnetic indicator coils (30) included in surgical devices, examples of surgical devices (20) including guidewires; surgical instruments including dilators, stents, catheters, jejunostomy tubes, and endoscopes; and indicator clips (used for marking a location within patient). An innovative device indicator is attachable to any surgical instrument to convert it to an electromagnetically monitorable instrument. A monitoring unit (50) detects electromagnetic fields from the electromagnetic indicator coils and displays the location and configuration of the electromagnetic indicator coils on a display unit (80). The relative positions and overall configuration of multiple devices—such as guidewires, instruments, and location marker indicator clips—can all be simultaneously electromagnetically monitored with the use of radiology.

Abstract: A locking syringe with an integrated bias member, for delivering medical fluids at high pressure, can include a housing, a shaft, a piston, a cap assembly, a bias member, and a locking member. A distal end of the housing can interface with a patient delivery apparatus. A piston can be connected to the distal end of the shaft and can include a peripheral sealing surface that can slidably engage the inside surface of the housing to form a movable seal. The cap assembly at the proximal end of the housing can engage the shaft. A base cap can secure the piston within the housing. The bias member can have a distal end coupled to the piston and a proximal end restrained, such as to help pressurize the internal cavity. The user-actuatable locking member can user-selectively engage and inhibit unwanted movement of the shaft.

Abstract: A medical device includes a control interface for operating the medical device in a hands-free mode. To control the medical device in a hands-free mode, the control interface includes multiple proximity sensors, each sensor associated with a level of adjustment. For example, a sensor located on a top portion of the medical device is used to increase the level of adjustment. And similarly, a sensor located on a bottom portion of the medical device is used to decrease the level of adjustment. The magnitude of the level of adjustment applied to a parameter of the medical device is controlled based at least in part on the length of time an object remains in proximity to a respective sensor. In one embodiment, the longer the object is held over a respective sensor the more adjustment the control interface will make to the parameter.

Abstract: A system and method of tracking a medical device and generating an image of a target area. The medical device includes a tracking device to create an imaging field-of-view that extends beyond the tip of the medical device while allowing the tip of the medical device to be visualized. The medical device further includes an imaging/visualization device to create an imaging field from the point of view of the medical device. A voltage standing wave suppression device is formed on the exterior surface of the medical device to prevent the formation of voltage standing waves and localized tissue heating. The voltage standing wave suppression device includes two cable traps spaced apart from one another with each cable trap being formed of a closely packed coiled region of a conductor extending the length of the medical device.

Abstract: Image tracking systems, and corresponding methods, are described. In some embodiments, conventional imaging components are placed on a platform having wheels, thereby providing a mechanism for imaging a moving subject. In other embodiments, conventional imaging components are situated on non-parallel rails, and moved along those rails, thereby providing a mechanism for imaging an anatomical region of a subject as that region moves in two dimensions. For yet other embodiments, image recognition and tracking approaches are provided to track the movement of a non-stationary anatomical region. The tracking of the non-stationary anatomical region permits imaging of a moving anatomy. For some embodiments, the anatomy moves within its normal range of motion.

Abstract: An elastographic imaging system providing for axial, lateral and elevational strain measurements employs a series of one-dimensional axial measurements to deduce a coarse axial, lateral and/or elevational displacement that is used to guide one or more, two- or three-dimensional cross-correlations of smaller kernels providing improved image resolution.

Abstract: RF signals in predetermined time regions are extracted respectively from a plurality of RF signals which are produced when an examinee is scanned by an ultrasonic wave, and respective IB values are calculated in the time regions. A variance value of the calculated IB values is calculated, and information based on the calculated variance value is output.

Abstract: Methods and systems for in vivo classification of tissue are disclosed. The tissue is irradiated with light from multiple light sources and light scattered and fluoresced from the tissue is received. Distinct emissions of the sample are identified from the received light. An excitation emission matrix is generated (1002). On-diagonal and off diagonal components of the excitation emission matrix are identified (1004, 1006, 1008). Spectroscopic measures are derived from the excitation emission matrix (1014), and are compared to a database of known spectra (1016) permitting the tissue to be classified as benign or malignant (1018). An optical biopsy needle or an optical probe may be used to contemporaneously classify and sample tissue for pathological confirmation of diagnosis.

Abstract: A hyperspectral imaging system having an optical path. The system including an illumination source adapted to output a light beam, the light beam illuminating a target, a dispersing element arranged in the optical path and adapted to separate the light beam into a plurality of wavelengths, a digital micromirror array adapted to tune the plurality of wavelengths into a spectrum, an optical device having a detector and adapted to collect the spectrum reflected from the target and arranged in the optical path and a processor operatively connected to and adapted to control at least one of: the illumination source; the dispersing element; the digital micromirror array; the optical device; and, the detector, the processor further adapted to output a hyperspectral image of the target.

Abstract: A device for measuring light scattering and absorption properties of a tissue, the device comprising: a probe comprising first and second optical fibers for irradiation and detection. The optical fibers are substantially parallel to each other at the distal end, and are separated by a distance of less than 2 mm, wherein said first and second optical fibers are arranged in said probe at an angle, 6=10 deg. to 45 deg., to the plane perpendicular to the distal end of said probe and wherein the tips of the optical fibers at the distal end are polished parallel to the plane perpendicular to the distal end of said probe.

Abstract: The present invention provides an ultrasound system, which comprises: a signal acquiring unit to transmit an ultrasound signal to an object and acquire an echo signal reflected from the object; a signal processing unit to control TGC (Time Gain Compensation) and LGC (Lateral Gain Compensation) of the echo signal; a TGC/LGC setup unit adapted to set TGC and LGC values based on TGC and LGC curves inputted by a user; and an image producing unit adapted to produce an ultrasound image of the object based on the echo signal. The signal processing unit is further adapted to control the TGC and the LGC of the echo signal based on the TGC and LGC values set by the TGC/LGC setup unit.