Abstract: Feedback of position is provided for high intensity focused ultrasound. The location of a beam from a HIFU transducer is determined using ultrasound imaging. The ultrasound imaging detects tissue displacement caused by a beam transmitted from the HIFU transducer. The displacement or information derived from the displacement may be used to detect and image the location of the beam. Separate transducers may be used for HIFU and imaging. The user aims the HIFU transmissions with feedback from ultrasound imaging of displacement of tissue.

Abstract: A method for determining an item of positioning information for ECG electrodes during an examination with a magnetic resonance facility is provided. An image data record of a region surrounding the heart of a patient and the electrodes arranged on the surface of the patient is recorded. A position of the longitudinal heart axis and a position of the electrodes in the image data record are determined. A target position suited to determining evaluable ECG signals is automatically calculated for each of the electrodes by considering the position of the longitudinal heart axis and a displacement from the position of the electrodes to the target position. An item of positioning information for the electrodes is displayed by taking the displacements into consideration.

Abstract: A plurality of concepts related to HIFU therapy are disclosed, including a technique to spatially track and display the relative positions of a HIFU focal point and an imaging plane from an ultrasound imager, so that a clinician can ensure that the HIFU focus remains in the image plane during HIFU therapy, thereby facilitating image guided HIFU therapy. Also disclosed are a plurality of transvaginal probes that include a HIFU transducer optimized for the treatment of uterine fibroids. In one embodiment, the probe includes a piezoceramic crystal bonded to an aluminum lens, to achieve a HIFU transducer having a focal length of about 4 cm. In another embodiment, the probe includes a generally spoon-shaped transducer including a plurality of individual emitter elements. Still another concept disclosed herein is a method for evaluating a quality of a coupling between a liquid-filled volume encompassing a HIFU transducer and a tissue interface.

Abstract: Adaptive persistence processing on elastic images in an ultrasound system is disclosed. An ultrasound data acquisition unit sequentially acquires a plurality of ultrasound data frames based on ultrasound echo signals reflected from a target object by repeatedly applying and releasing stress to/from the target object. A processing unit calculates inter-frame displacements of the frames between the ultrasound data frames to form elastic images. The processing unit adaptively performs persistence processing on the elastic images in consideration of application or release of the stress to/from the target object.

Abstract: An ultrasonic diagnostic apparatus is disclosed for transmitting ultrasonic waves and receiving echo signals. The apparatus includes an ultrasonic probe having transducers whose sensitivity can be controlled in accordance with bias voltage. Echo signals output from the ultrasonic probe are amplified so that an image can be constructed according to the amplified echo signals and displayed. A probe gain control device is used for controlling the bias voltage in accordance with the elapsed time from receiving the echo and matching the intensity of the echo signal output from the ultrasonic probe with the input range of a preamplifier. During a reception period while a strong echo signal is received from a superficial portion of body surface of an examinee, the reception sensitivity of the ultrasonic probe is controlled so that the echo signal level input to the preamplifier will not exceed the input range of the preamplifier.

Abstract: There is described a system for carrying out and monitoring minimally-invasive interventions with an x-ray device, in which at least one x-ray emitter and a x-ray detector are attached to one or more robot arms of one or more multi-axis articulated-arm robots, with which they are able to be moved for recording images from different projection directions on a predeterminable path around a patient support facility. The system includes a control and evaluation unit with interfaces for catheters and devices for carrying out the minimally-invasive intervention. The control and evaluation unit is embodied for the processing of measurement and/or image data which it receives from the catheters and devices and for control of the catheters and devices for recording the measurement and/or image data. With the proposed system the workflow is covered completely and seamlessly from the examination to the therapy, especially in the treatment of tachycardial arrythmias.

Abstract: An apparatus for diagnosing a patient includes a catheter having a tip. The apparatus includes a bioptome disposed in proximity to the tip to obtain a tissue sample of the patient. The apparatus includes a radiodetector disposed in proximity to the tip to detect radiation in the patient. A method for diagnosing a patient includes the steps of moving a tip of a catheter to a desired location in a blood vessel of the patient determined by radiation detected by a radiodetector disposed in proximity to the tip. There is the step of obtaining a tissue sample of the patient with a bioptome disposed in proximity to the tip.

Abstract: A handheld ultrasound probe includes force detection and feedback to permit control and/or characterization of applied forces. The probe may, for example, be operated to maintain a substantially constant applied force over a period of use independent of a user's hand position, or to measure applied forces that might contribute to deformation of an imaging subject.

Abstract: When delivering a therapy to a patient, such as a drug to a brain of a patient, an optimized delivery point can be selected. The optimized point can be based on physics, physiology, and pharmacology. The optimized point can be used for planning a surgical navigation procedure.

Abstract: A wave-based tomographic imaging method and apparatus based upon one or more rotating radially outward oriented transmitting and receiving elements have been developed for non-destructive evaluation. At successive angular locations at a fixed radius, a predetermined transmitting element can launch a primary field and one or more predetermined receiving elements can collect the backscattered field in a “pitch/catch” operation. A Hilbert space inverse wave (HSIW) algorithm can construct images of the received scattered energy waves using operating modes chosen for a particular application. Applications include, improved intravascular imaging, bore hole tomography, and non-destructive evaluation (NDE) of parts having existing access holes.

Abstract: This invention relates to a device for retrieving information about one or more states of a mammalian body comprising: (a) a magnetic resonance imaging device comprising a first set of one or more radio-frequency coils for measuring the body temperature Ti at a selected location of a mammalian body, (b) a local heating means including a second set of one or more radio-frequency coils, said second set comprising at least two channels for delivering focused radio frequency energy to said selected location of said mammalian body and raising the temperature Ti thereof, and (c) means for modulating said radio-frequency energy delivered by said second set of coils as a function of said temperature Ti in order to reach and maintain a predefined temperature Tp above the normal mammalian body temperature Tb.

Abstract: The invention relates to a method for detecting properties or alterations in at least one semitransparent layer of a body of a tooth by applying light escaping from at least one light guide via the front thereof to the body, as well as for recording at least one area of the body by means of a camera and subsequently assessing the image determined by the sensor. In order to be able to detect alterations or properties with high accuracy and a high image quality, it is proposed to place the front of the light guide on the body in order to subject the body to the light of the light guide.

Abstract: A handheld ultrasound probe includes force detection and feedback to permit control and/or characterization of applied forces. The probe may, for example, be operated to maintain a substantially constant applied force over a period of use independent of a user's hand position, or to measure applied forces that might contribute to deformation of an imaging subject.

Abstract: A patient treatment unit for analyzing and treating abnormality of human or animal tissues, includes a display; a pulse generator circuit that outputs a sequence of electrical pulses at a pulse frequency, the electrical pulses having a pulse width, the pulse generator controlling the pulse frequency and the pulse width of the electrical pulses; a pair of probes for contacting a body of a patient and electrically coupled to the pulse generator; and a voltage and current sensing circuit that senses a voltage or a current via the probes when contacting the body of the patient.

Abstract: The invention provides, in a method of perfusion magnetic resonance imaging of a region of interest in a vascularized animal subject, said method comprising administering a contrast agent bolus into the vascular system of said subject; determining the magnetic resonance signal strength si(t) for voxels (i) of said region of interest at a series of time values (t) over a period from before contrast agent arrival in said region of interest to at least the end of the first pass of said contrast agent through said region of interest; from the determined values si(t) for said signal strength and an arterial input function v(t), determining values for the tissue residue function ri(t) for each said voxel; and optionally generating an image of said region of interest from the determined values of ri(t); the improvement comprising generating from si(t) a voxel specific arterial function vi(t) and using said voxel specific arterial function to determine the values of the tissue residue function ri(t).

Abstract: Macular pigments are measured by spectrally selective lipofuscin detection. Light from a light source that emits light at a selected range of wavelengths that overlap the absorption band of macular carotenoids is directed onto macular tissue of an eye for which macular pigment levels are to be measured. Emitted light is then collected from the macular tissue. The collected light is filtered so that the collected light includes lipofuscin emission from the macular tissue at an excitation wavelength that lies outside the macular pigment absorption range and outside the excitation range of interfering fluorophores. The collected light is quantified at each of a plurality of locations in the macular tissue and the macular pigment levels in the macular tissue are determined from the differing lipofuscin emission intensities in the macula and peripheral retina.

Abstract: Minimally invasive systems and methods are described for measuring pulmonary circulation information from the pulmonary arteries. A transbronchial Doppler ultrasound catheter is advanced through the airways and in the vicinity of the pulmonary artery. Doppler ultrasound energy is sent through the airway wall and across the pulmonary artery to obtain velocity information of blood flowing through the artery. The velocity information is used to compute pulmonary circulation information including but not limited to flowrate.

Abstract: A system for video based registration between images during a skeletal medical procedure includes a stereoscopic camera, a two dimensional image detector and a registration processor. The camera is associated with a stereoscopic coordinate system, the camera acquires a stereoscopic image pair of fiducial marks fixed onto a skeletal structure. Fiducial representations of the fiducial marks appear on the stereoscopic image pair, and a skeletal representation of the skeletal structure appears on two different 2D images. The registration processor registers a stereoscopic coordinate system with a 3D coordinate system associated with a volumetric image detector, and superimposes 3D information on at least one volumetric image. The registration processor registers the stereoscopic coordinate system with the 3D coordinate system by registering the stereoscopic coordinate system with the 2D coordinate system and by registering the 2D coordinate system with the 3D coordinate system.

Abstract: A portable system can be provided that works with a surgical navigation system. The portable system can control a localizer to assist in the tracking of a tracking device. The portable system can be provided to be substantially carried by a single user form one location to another. Further, various digital control components can be provided to assist in miniaturization, robustness, and the like.

Abstract: A thermal treatment system including a heat applying element for generating thermal doses for ablating a target mass in a patient, a controller for controlling thermal dose properties of the heat applying element, an imager for providing preliminary images of the target mass and thermal images during the treatment, and a planner for automatically constructing a treatment plan, comprising a series of treatment sites that are each represented by a set of thermal dose properties. The planner automatically constructs the treatment plan based on input information including one or more of a volume of the target mass, a distance from a skin surface of the patient to the target mass, a set of default thermal dose prediction properties, a set of user specified thermal dose prediction properties, physical properties of the heat applying elements, and images provided by the imager.