Abstract: Systems and methods are disclosed to determine one or more sensing zones on a body surface for electrocardiographic mapping of a region of interest associated with the heart. The sensing zone can be utilized to facilitate acquisition, processing and mapping of electrical activity for the corresponding region of interest. In other examples, an application-specific arrangement of electrodes can also be provided based on the sensing zone that is determined for the region of interest.
Type:
Grant
Filed:
December 6, 2021
Date of Patent:
November 28, 2023
Assignee:
CARDIOINSIGHT TECHNOLOGIES INC.
Inventors:
Ping Jia, Charulatha Ramanathan, Maria Strom, Brian P. George, Lalita Bhetwal, Harold Wodlinger, Jonathan D. Small
Abstract: Presented herein are techniques for adapting/transitioning operation of a medical prosthesis, such as an auditory prosthesis, from a first or initial group of settings to a second or target group of settings. The adaptation in the operation of the medical prosthesis from the first group of settings to the second group of settings occurs over a period of time and in a series of individualized (recipient-specific) incremental steps. That is, the adaptation process occurs in incremental steps that are set based on attributes/characteristics of the recipient of the specific medical prosthesis so that the adaptation is made as unobtrusive to the recipient as possible.
Abstract: The disclosure relates to an implant comprising a housing, in which there are arranged an energy store and an electronics module, wherein a feedthrough to an electrode connection device is formed on the housing, wherein a first contact forms an electrical connection between the energy store and the electronics module, wherein a second contact forms an electrical connection between the electronics module and the feedthrough, and wherein the first contact and the second contact are oriented in the same contact direction. A method for assembling an implant is also disclosed.
Type:
Grant
Filed:
July 22, 2019
Date of Patent:
November 14, 2023
Assignee:
BIOTRONIK SE & Co. KG
Inventors:
Thomas Doerr, Ulrich Feese, Rolf Klenner, Torsten Oertmann
Abstract: A method for treating pain or discomfort in a patient is disclosed. The method comprises stimulating a cranial nerve with an electrical signal. The pain or discomfort may be a withdrawal symptom. The cranial nerve may be in an auricular area of the patient. The cranial nerve may be cranial nerve V, cranial nerve VII, cranial nerve IX, cranial nerve X, or branches of greater and lesser occipital nerves thereof and their associated neurovascular bundles. The withdrawal symptom may result from cessation of an opioid. The method may further comprise administering a secondary drug treats one or more of the withdrawal symptoms and addiction. The secondary drug may be administered about one day to about one week after initiating the stimulating step.
Abstract: A system and method for treating sleep apnea includes inserting an implantable pulse generator subcutaneously within a body of a patient and connecting a lead to the pulse generator. The lead is inserted within the vasculature and advanced transvenously through the vasculature until a stimulation portion of the lead becomes positioned in close proximity to the hypoglossal nerve. A nerve-stimulation signal is applied to the hypoglossal nerve via the stimulation portion of the lead.
Type:
Grant
Filed:
August 6, 2021
Date of Patent:
November 7, 2023
Assignee:
INSPIRE MEDICAL SYSTEMS, INC.
Inventors:
Quan Ni, Mark A. Christopherson, Timothy P. Herbert, John Rondoni
Abstract: An electronic device is disclosed that includes: communication circuitry, a memory operatively coupled to a processor and storing instructions which, when executed, cause the processor to: receive first physiological data and second physiological data obtained by measuring a physiological state of a user's body, obtain measurement environment data for an environment where each of the first physiological data and the second physiological data is measured, determine validity of each of the first physiological data and the second physiological data based on at least a portion of the measurement environment data, generate integrated data of the first physiological data and the second physiological data based on at least one of comparing the first physiological data with the second physiological data and the measurement environment data, based on the first physiological data and the second physiological data being valid, and control a display to display the integrated data on the display.
Abstract: Computer implemented methods and systems for monitoring cardiac activity (CA) signals, for a series of beats, over first and second sensing channels having different first and second detection thresholds, respectively. The methods and systems also include analyzing the CA signals over the first and second sensing channels utilizing the first and second detection thresholds, respectively, during an event prediction window to detect a presence of sensed events. The methods and systems also include determining amplitudes of the sensed events detected. The methods and systems also include calculating at least one of an amplitude distribution or amplitude trend for the sensed events detected over the first and second channels and adjusting at least one of the first or second detection thresholds based on the at least one of the amplitude distribution or amplitude trend.
Abstract: A wearable garment includes a compression fabric with at least one electrode coupled to the compression fabric or sewn into seams of the wearable garment. The electrode includes a first layer comprising a metal integral conductive silicone rubber material configured to lay proximate to a wearer of the garment. The electrode may also include a second layer including a conducting metal sheet and a conductive lead coupled to the second layer. A non-conducting layer is configured to lay proximate to the compression fabric.
Abstract: A medical device processor is configured to receive a first cardiac electrical signal sensed from a first sensing electrode vector, receive a second cardiac electrical signal sensed from a second sensing electrode vector different than the first sensing electrode vector, and construct a third cardiac electrical signal from the first cardiac electrical signal and the second cardiac electrical signal. In some examples, the system determines sensed cardiac events according to at least one setting of a cardiac event sensing threshold control parameter from at least the third cardiac electrical signal and may determine at least one acceptable setting of a sensing control parameter based on the determined sensed cardiac events. The processor may generate an output representative of the determined sensed cardiac events.
Abstract: A bone stimulating method and device for treating injured or diseased bone tissue, includes exposing the injured or diseased bone tissue to a first electric field over a predetermined treatment period, the first electric field ranging from 10 mV/cm to 40 mV/cm and having a first predetermined time period within the predetermined treatment period and exposing the injured or diseased bone tissue to a second electric field over the predetermined treatment period, the second electric field ranging from 10 mV/cm to 60 mV/cm and having a second predetermined time period within the predetermined treatment period that is greater than the first predetermined time period.
Abstract: A method of monitoring depth of muscle relaxation of a patient includes determining a sedative drug effect of one or more sedative drugs on a patient based on at least one of drug delivery information and measured nervous system information. The sedative drug effect is then compared to a sedation criterion and, if the sedative drug effect fulfills the sedation criterion, then a neuromuscular transmission (NMT) monitor is controlled to apply a series of stimulation to a nerve of a patient and muscle responses of the patient are measured to obtain an NMT baseline. A neuromuscular blocking agent (NMBA) notice is then generated on a user interface after obtaining the NMT baseline.
Abstract: This disclosure relates to methods for measuring one or more physiological signals while the user is engaged in a predetermined activity. Exemplary predetermined activities can include activities such as walking, climbing stairs, biking, and the like. The physiological measurements can include, but are not limited to, heart rate signals. The physiological measurements may be affected by the predetermined activity, so the system may be configured to employ one or more criteria prior to measuring physiological information to minimize the effects. The one or more criteria can include, but are not limited to, an inter-sampling waiting time, continuous motion criteria, predetermined activity criteria, a post-physiological measurement amount of time, and a confidence value. The continuous motion criteria can be based on the type of predetermined activity. For example, walking may have walking state criteria and a step count criteria.
Type:
Grant
Filed:
November 8, 2021
Date of Patent:
October 17, 2023
Assignee:
Apple Inc.
Inventors:
Siyi Deng, Stephen J. Waydo, Jay Blahnik, Lun Dong, Ian R. Shapiro
Abstract: A system and method for identifying and treating a disease in a patient collects one or more data streams from sensors configured to detect biological signals generated within a patient's tissue over time. Patient data elements including one or more of demographic, clinical, laboratory, pathology, chemical, image, historical, genetic, and activity data for the patient is collected and processed with the data streams to generate a personalized digital phenotype (PDP). The PDP is compared to a digital taxonomy comprising prior data to classify the patient into one or more quantitative disease classifications to guide personalized intervention for treating the patient.
Type:
Grant
Filed:
April 24, 2019
Date of Patent:
October 17, 2023
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Abstract: A peripheral nerve conduction diagnosis system that utilizes an electrostimulation device having dry elastomer electrodes and a distance measuring device that allow a user to move the electrostimulation device along the skin of a patient while in constant contact with the skin and measure the distance moved.
Abstract: Devices, systems and methods are disclosed for electrical stimulation of the vagus nerve to treat or prevent disorders in a patient. The methods comprise transmitting impulses of energy to the vagus nerve according to a treatment paradigm. The treatment paradigm may include generating and transmitting the electrical impulse as a single dose from about 30 seconds to about 5 minutes. The treatment paradigm may comprise a treatment session of 2 to 4 times within an hour time period and/or as a single dose from 2 to 5 times during a day.
Abstract: An implantable medical device (IMD) includes an adjustable capacitive voltage multiplier (CVM) that is responsive to diagnostic circuitry configured to provide control signals within a single stimulation current pulse for adjusting the voltage output applied to an electrode of the IMD's lead system. A control counter is coupled to the diagnostic circuitry for incrementing or decrementing an N-bit counter output signal operative to reconfigure a charge pump arrangement of the CVM so as to facilitate an adjusted voltage output.
Type:
Grant
Filed:
October 12, 2021
Date of Patent:
October 10, 2023
Assignee:
Advanced Neuromodulation Systems, Inc.
Inventors:
Daran DeShazo, Steven Boor, Gavin L. Rade
Abstract: A medical device is configured to receive sensed cardiac event data including a value of a feature determined from each one of a plurality of cardiac events sensed from a cardiac signal according to a first setting of a sensing control parameter. The medical device is configured to classify each value of the feature of each one of the sensed cardiac events as either a predicted sensed event or a predicted undersensed event according to a second setting of the sensing control parameter that is less sensitive to sensing cardiac events than the first setting. The medical device is configured to determine a predicted sensed event interval between each consecutive pair of the predicted sensed events and predict that an arrhythmia is detected or not detected based on the predicted sensed event intervals.
Abstract: An implantable medical device stimulates a human or animal heart. The medical device contains a processor, a memory unit, a His electrode having a first electrode pole configured to detect an electrical signal at a His bundle of a heart, and a further electrode having a further electrode pole configured to detect an electrical signal at a cardiac region of the same heart different from the His bundle. During operation of the device, performing the steps of: measuring electric signals at a His bundle of a heart with the first electrode pole; measuring electric signals at a cardiac region of the same heart different from the His bundle with the further electrode pole; and evaluating intracardiac electrogram signals and/or impedance signals measured between the first electrode pole and the further electrode pole, with the provision that this evaluating does not only contain a determination of an atrial-His bundle transition time.
Abstract: A method of modifying tissue behavior, comprising: determining a desired modification of tissue behavior for at least one of treatment of a disease, short or long term modification of tissue behavior, assessing tissue state and assessing tissue response to stimulation; selecting an electric field having an expected effect of modifying protein activity of at least one protein as an immediate response of a tissue to the field, said expected effect correlated with said desired modification; and applying said field to said tissue.
Type:
Grant
Filed:
November 11, 2021
Date of Patent:
October 10, 2023
Assignee:
Impulse Dynamics NV
Inventors:
Benny Rousso, Yuval Mika, Shlomo Ben-Haim, Hani N. Sabbah
Abstract: A method, device and a computer program product for determining a training load distribution of a user is provided. Heart rate is continuously measured by a heart rate sensor. An aerobic training effect and load are calculated using intensity values and divided into categories of Aerobic Low and Aerobic High. An anaerobic training effect and load are calculated using determined characteristics related to high intensity periods of an exercise.
Type:
Grant
Filed:
February 19, 2020
Date of Patent:
October 3, 2023
Inventors:
Mikko Seppänen, Johanna Toivonen, Aki Pulkkinen, Perttu Luukko, Sami Saalasti, Tero Myllymäki, Veli-Pekka Kurunmaki, Tuukka Ruhanen