Abstract: The present invention provides herbal formulations, methods for their preparation, and methods of treating herpes simplex. The formulations can provide good permeability and bioavailability at the target site.
Abstract: The extract of a mixture of cinnamon twig and moutan root bark, cinnamon twig and peony root, or cinnamon twig and poria according to the present invention has been confirmed to inhibit the excessive generation of advanced glycation end-products, which occurs under chronic diabetic conditions, exhibit the effect of fragmentizing a cross-link between the advanced glycation end-products and matrix proteins, have an excellent effect in inhibiting the generation of the advanced glycation end-products in a human retinal pigment epithelial cell line subjected to a hyperglycemic or aging environment, and have excellent effects in delaying, preventing, and treating diabetic complications, muscular degeneration, commotio retinae, and lower extremity edema in various animal models of diabetic complications, macular degeneration, and lower extremity edema, and thus the mixture extract can effectively be used as an active ingredient for a composition for preventing and treating diabetic complications, including diabetic
Type:
Grant
Filed:
May 21, 2015
Date of Patent:
December 7, 2021
Assignee:
KOREA INSTITUTE OF ORIENTAL MEDICINE
Inventors:
Jin Sook Kim, Junghyun Kim, Chan-Sik Kim, Eunjin Shon, Yun Mi Lee, Sojin Choi, Ik Soo Lee, Young Sook Kim, Dong Ho Jung, Bo-Jeong Pyun, Seung-Hyun Jung
Abstract: The present disclosure envisages a mouth freshener composition comprising the extracts of Curcuma longa, Piper longum and Mentha arvensis. Further, the composition comprises at least one diluent, at least one sweetening agent, at least one binder, at least one preservative, at least one pharmaceutically acceptable fluid medium, at least one pharmaceutically acceptable flavoring agent, at least one pharmaceutically acceptable lubricant, optionally at least one pharmaceutically acceptable disintegrant, at least one pharmaceutically acceptable glidant, at least one pharmaceutically acceptable film forming agent, at least one pharmaceutically acceptable plasticizer. The present disclosure also envisages a process for preparing the mouth freshener composition. The mouth freshener composition alleviates halitosis, common cold, cough, sore throat and the symptoms of bronchitis. It also acts as a rejuvenator and Immunomodulator on prolonged use.
Abstract: Provided are compositions comprising compounds or precursors to compounds which may be used for a variety of therapeutic applications including, for example, treating and/or preventing a disease or disorder related to reduced or inadequate mitochondrial activity, including aging or stress, diabetes, obesity, and neurodegenerative diseases. The compounds relate generally to urolithins and precursors thereof, including but not limited to ellagitannins and urolithin A. In certain embodiments the compositions are presented in or as food products or nutritional supplements. These same compounds and compositions can also be used advantageously in generally healthy individuals to increase or maintain metabolic rate, decrease percent body fat, increase or maintain muscle mass, manage body weight, improve or maintain mental performance (including memory), improve or maintain muscle performance, improve or maintain mood, and manage stress.
Type:
Grant
Filed:
June 18, 2018
Date of Patent:
November 9, 2021
Assignee:
Amazentis SA
Inventors:
Christopher L. Rinsch, William Blanco-Bose, Bernard Schneider, Charles Thomas, Carmen Sandi, Johan Auwerx, Penelope Andreux, Richardus Houtkooper, Eija Pirinen, Laurent Mouchiroud, David Genoux
Abstract: The present disclosure describes methods of obtaining and/or deriving proteins from plants of the Nicotiana species and methods for incorporation of such proteins into various products. For example, a method for obtaining a protein-enriched material from a plant of the Nicotiana species or portion thereof is provided, comprising: extracting one or more proteins from the plant material into a solvent to form a liquid protein-containing extract; separating a solid extracted plant material from the liquid protein-containing extract; clarifying the liquid protein-containing extract to form a clarified protein-containing extract and a solids fraction; and treating the clarified protein-containing extract so as to provide a protein-enriched material comprising at least about 60% protein by weight.
Type:
Grant
Filed:
March 14, 2016
Date of Patent:
November 9, 2021
Assignee:
R.J. Reynolds Tobacco Company
Inventors:
John-Paul Mua, Kyle Ford, Leigh Ann Blevins Joyce, Margarette Elisa Lovette, Joshua D. Morton, Leigh Hagan, Barry Bratcher, Samuel Mark Debusk
Abstract: The present invention relates to extracts, compounds isolated from Cakile arabica for use in the treatment of ulcer and to pharmaceutical compositions thereof.
Abstract: Provided herein are clear aqueous colonoscopy irrigation compositions, and methods for visualization of colonic mucosa during colonoscopy procedure. The composition comprises indigo, blue or green colored contrast dye, polydimethylsiloxane, and muscle relaxant.
Abstract: Composition for treatment and management of addiction and method of preparation thereof are disclosed herein. The disclosed herbal composition includes herb and mineral which facilitate in treating addiction. It may be used to treat addiction such as alcohol addiction, tobacco addiction, excessive smoking, drugs abuse etc. Further, the disclosed composition may also be instrumental in treating complications associated with addiction and withdrawal symptoms.
Abstract: Provided is a natural shampoo composition containing a white dandelion extract solution, and more particularly, to a natural shampoo composition containing a white dandelion extract solution, a Portulaca oleracea L. extract and a red Ginseng which has excellent washing effect and hair loss prevention effect and hair growth promotion effect.
Abstract: A composition and method for the controlled release of natural plant oils (essential oils) from a wax matrix to repel insects, arachnids, and other arthropods.
Abstract: The present disclosure relates to the technical field of traditional Chinese medicine technology, especially to a composition, a preparation method thereof and an application in the prevention and treatment of mammary gland diseases. The present disclosure provides a composition consisting of Rehmanniae Radix Praeparata, Lycii Fructus, Polygonati Rhizoma, Radix Codonopsis Pilosulae, Paeoniae Radix Alba, Cyperi Rhizoma (processed with vinegar) and Grape Seed. The composition has functions of improving hyperplasia of mammary gland and/or anti-oxidation. Compared with each control group, the composition provided by the present disclosure has the optimal effects, and the effect has statistical differences, indicating that the components in the composition provided by the present disclosure are reasonably arranged and can play a good synergistic effect. Furthermore, the preparation is safe and has no side effects.
Abstract: Provided is a pharmaceutical composition for preventing or treating inflammatory bowel disease (IBD) comprising a mixed extract of at least two of Aucklandia lappa Decne, Terminalia chebula Retzius, and Zingiber officinale Rosc. as an active ingredient and a method thereof, and more specifically, to a pharmaceutical composition having an inhibitory effect on monocyte adhesion in intestinal epithelial cells, an effect of inhibiting the production of inflammatory cytokines, an effect of ameliorating colitis in an animal model of dextran sodium sulfate (DSS)-induced colitis, and an effect of ameliorating Crohn's disease in an animal model of 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced Crohn's disease.
Type:
Grant
Filed:
November 4, 2016
Date of Patent:
September 21, 2021
Assignee:
GENUONE SCIENCES INC.
Inventors:
Yong-baik Cho, Seul-ki Kim, Sang-Back Kim, Jae-hyuck Shin, Young-ran Um, So-youn Mok, Ju-ri Jung, Soon-min Lim, Chae Shin Seo, Hong Koo Cho, Bon Am Koo, Hyo Jin Jeon, Han-Seok Choi, Ye Jin Kim
Abstract: Disclosed are an extract that is effective in treating drug addiction and a preparation method therefor. An effective component of the extract has the following chemical structural characteristics: a cholestenol compound with hydroxyl (OH) at position 3 and a double bond between position 5 and position 6, or a cholestenol compound with hydroxyl (OH) at position 3, a double bond between position 5 and position 6 and a double bond between position 22 and position 23. The extract can be extracted from the traditional Chinese medicine Agriolima agrestis. The extract of the present invention is safe in acute toxicity, sedative and hypnotic without physical and psychic dependence, has an inhibitory effect on excitability in mouse caused by morphine and benzedrine and a detoxification treatment effect on the withdrawal symptoms in morphine-dependent rats, and is useful in the development of medications or food for treating drug addiction.
Abstract: An improved method for making a P. vulgaris bean extract that results in an extract having high ?-amylase inhibitory activity and low hemagglutinin activity. The method involves treating the beans to selectively denature the hemagglutinin. A P. vulgaris bean extract is provided, having high ?-amylase inhibitory activity and low hemagglutinin activity. A treatment for diabetes or method for reducing blood glucose level is disclosed using the P. vulgaris bean extract disclosed herein.
Abstract: An aqueous formulation comprising between 0.1% and 50% by weight of lipophilic composition, said formulation further comprising between 0.1% and 10% by weight of homogenising component comprising at least microcrystalline cellulose; between 0.01% and 2% by weight of clay; and the remainder in water.
Abstract: Microsclerotia of entomopathogenic fungi, including Metarhizium species, Beauveria species, and Lecanicillium species, may be produced. These microsclerotia are effective for the control of a wide variety of insect pests, particularly soil-dwelling insect pests.
Type:
Grant
Filed:
September 15, 2015
Date of Patent:
July 13, 2021
Assignee:
The United States of America, as represented by The Secretary of Agriculture
Abstract: A method for reducing skin inflammation or reducing sebum production from sebaceous glands is disclosed. The method can include topically applying to skin in need thereof a composition comprising Psidium guajava fruit extract and Kunzea ericoides leaf extract, wherein topical application of the composition reduces skin inflammation or sebum production from sebaceous glands.
Abstract: The present invention discloses a composition comprising extracts of Cyperus rotundus, standardized to contain 3-5% w/w total stilbenes, extracts of Garcinia sp., standardized to contain 20% w/w garcinol and extracts of Coleus forskohlii standardized to contain not less than 10% w/w forskolin for the therapeutic management of diet induced obesity and weight gain and related conditions like liver dysfunction, NASH, NAFLD, liver cirrhosis, hypercholesterolemia, hyperlipidemia, kidney dysfunction by bringing about a reduction in body weight, increasing lean body mass and by normalizing the levels of liver enzymes, kidney markers and circulating lipids.
Abstract: The present disclosure provides a Pennisetum extract, process for manufacturing the same, and uses thereof for inhibiting differentiation and/or activation of osteoclast, and prevention and/or treatment of osteoporosis.
Type:
Grant
Filed:
November 29, 2018
Date of Patent:
June 15, 2021
Assignee:
METAL INDUSTRIES RESEARCH & DEVELOPMENT CENTRE
Inventors:
Ren-Wei Su, Pei-Jung Lien, Yu-Ren Huang, Tz-Choung Chou