Abstract: N-methyl pyrrolidone solvent (hereinafter NMP) used to extract aromatic components from lubricating oil distillates is purified by contacting the solvent with activated alumina.

Abstract: Compounds of the formula: ##STR1## The compounds are useful as pesticides, particularly insecticides.

Abstract: Disclosed herein is a novel chromogenic compound of the formula: ##STR1## wherein R represents an alkyl group of 6 to 12 carbon atoms or benzyl group, and ring A and ring B in the quinolyl group may be substituted, a color forming composition containing said chromogenic compound, and pressure- or heat-sensitive recording paper based on said color forming composition.

Abstract: Novel enantiomeric and diastereoisomeric forms of decahydroquinolines of the formula ##STR1## wherein R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen and alkyl of 1 to 5 carbon atoms or taken together with the nitrogen atom to which they are connected form a 5 to 6 member heterocycle optionally including another heteroatom and optionally substituted, A is selected from the group consisting of --(CH.sub.2).sub.n -- and alkylene substituted with an alkyl and having 2 to 8 carbon atoms, n is an integer from 0 to 5, Z is selected from the group consisting of optionally substituted phenyl, naphthyl indenyl, monocyclic heterocycle of 5 to 6 members and a bicyclic heterocycle all being unsubstituted or substituted by one or more substituents and their non-toxic, pharmaceutically acceptable acid addition salts and quaternary ammonium salts having central analgesic properties.

Abstract: Oxime esters of substituted quinoline-8-carboxylic acids of the formula ##STR1## where X is hydrogen, C.sub.1 -C.sub.4 -alkyl or halogen, Z is hydrogen or methyl, R.sup.1 is C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.4 -alkoxymethyl, C.sub.1 -C.sub.4 -alkoxyethyl, C.sub.1 -C.sub.4 -alkylthiomethyl, C.sub.1 -C.sub.4 -alkylthioethyl, C.sub.1 -C.sub.4 -alkoxycarbonyl, C.sub.3 -C.sub.6 -alkenyl or C.sub.5 -C.sub.8 -cycloalkyl, each of which is unsubstituted or bears up to 3 methyl substituents, hydrogen, cyano, acetyl, benzoyl, unsubstituted benzyl or phenyl, or benzyl or phenyl bearing up to 3 substitutents selected from the group consisting of halogen, cyano, trifluoromethyl, C.sub.1 -C.sub.4 -haloalkyloxy, C.sub.1 -C.sub.6 -alkylthio, C.sub.1 -C.sub.4 -alkoxy, C.sub.1 -C.sub.4 -alkyl, hydroxy, dimethylamino or acetamino, R.sup.2 is hydrogen if R.sup.1 is not hydrogen, R.sup.2 further denotes C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.4 -alkoxymethyl, chloromethyl, azolylmethyl, 1,1-dimethoxymethyl, cyano, C.sub.

Abstract: Novel diarylacetylenes of the formula I ##STR1## where A, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 have the meanings stated in the description, are useful for the treatment of dermatological disorders.

Abstract: The invention concerns compounds of formula: ##STR1## wherein R.sub.1 is hydrogen, lower alkyl, halogen, lower alkoxy or hydroxy; R.sub.2 represents hydrogen or lower alkyl; A represents an alkylene, oxoalkylene or hydroxyalkylene chain each having 2 to 6 carbon atoms, R.sub.3 and R.sub.4 may be in the same or different rings and independently represent hydrogen, lower alkyl, lower alkoxy, amino or halogen and one of X and Y represents nitrogen the other represents CR.sub.5 wherein R.sub.5 is one of the values for R.sub.3 or R.sub.5 is the bond to the NHCO group; or a pharmaceutically acceptable salt thereof, which compounds possess antihypertensive activity while exhibiting reduced CNS depressant properties. Also disclosed are processes for preparing the compounds and pharmaceutical compositions containing them.

Abstract: A one-step method for the reductive amination of a heterocyclic to produce a nitrogen-containing heterocyclic. The feedstock is contacted with a mixed metal catalyst in which the metal comprises palladium and one of ruthenium, rhodium or rhenium.

Abstract: Compounds of formula (I) or when a compound of formula (I) contain a salifiable group, a pharmaceutically acceptable salt thereof: ##STR1## wherein: R.sub.1 -R.sub.7 and X are as defined, are useful as anti-hypertensive agents.

Abstract: Quinoline derivatives of the formula ##STR1## where R.sup.1, X, Y and Z have the meanings given in the disclosure, herbicides containing these compounds as active ingredients, and a process for combating unwanted plant growth.

Abstract: A new compound, 3-(1H-tetrazol-5-yl)oxanilic acid and pharmaceutically acceptable salts thereof are herein disclosed, which can be prepared by reacting 3-(1H-tetrazol-5-yl)aniline with a compound represented by the general formula: A--CO--CO--B (wherein A and B may be identical with or different from one another and represent hydroxyl group, a halogen atom or a lower alkoxy group) and then optionally hydrolyzing the resultant product. The compound presents an excellent histamine and SRS-A release inhibitory effect and is hydrophilic or soluble in water. Therefore, the compound is very suitable to form, in particular, an aqueous pharmaceuticals for treatment or prevention of allergic diseases such as bronchial asthma, rhinitis and conjunctivitis.

Abstract: The invention relates to 1-aryloxy-2,3,4,5-tetrahydro-3-benzazepines of the formula ##STR1## wherein Y is the same of different and is hydrogen and lower alkoxy; X is hydrogen, halogen, lower alkyl, lower alkoxy, CF.sub.3, NO.sub.2, CN and NH.sub.2 ; R is hydrogen, lower alkyl, cycloalkyllower alkyl, ##STR2## Ar lower alkyl of the formula ##STR3## where Z is hydrogen, lower alkyl, lower alkoxy, halogen CF.sub.3, NO.sub.2 and NH.sub.2 ; Aryloxy lower alkyl of the formula ##STR4## where Z is as previously defined; and an alkylene amine of the formula ##STR5## where R.sub.1 and R.sub.2 are the same or different and are hydrogen and lower alkyl, n is an integer of 1 or 2; and the pharmaceutically acceptable acid addition salts thereof.

Abstract: A process for producing fine-grained .beta.-HMX wherein a solution of .beta.-HMX is treated in a .gamma.-lactone in a temperature range of between 5.degree. and 15.degree. C. with toluene, and the desired fine and very pure .beta.-HMX crystals are precipitated. The resultant crystals have grain sizes of down to 5 .mu.m and exhibit an extremely small proportion of other modifications or forms of HMX. An additional aspect of the process resides in providing the very fine .beta.-HMX with a coating of a thermoplastic polymer. In this procedure, the .beta.-HMX particles, after having been separated from toluene, are made into a slurry in water and combined under agitation at temperatures of between 25.degree. and 60.degree. C. with a solution or suspension or emulsion of the thermoplastic polymer. During this step, granules are formed which can be separated after distillation of the solvent.

Abstract: Cyclic N-hydroxyimide compounds derived from tartaric acid are provided which exhibit strong metal ion chelating ability, making them useful as detergent additives, in boiler water systems, as reaction intermediates, etc. A detergent composition containing N-hydroxyimide compounds as detergent additives is also disclosed.

Abstract: 5-aminopentanenitrile compounds of the formula: ##STR1## in which: Ar represents ##STR2## in which: R.sub.1 is hydrogen, halogen trifluoromethyl or C.sub.1 -C.sub.5 -alkoxy, andR.sub.2 and R.sub.3, which are identical or different, each are hydrogen or C.sub.1 -C.sub.5 -alkoxy or together form --O--CH.dbd.CH--O-- or --O--CH.sub.2 --O--; or together form with the phenyl ring to which they are bound a benzoxazolyl, benzothiazolyl, benzothiadiazolyl or quinolyl radical;R is C.sub.3 -C.sub.15 -alkyl or ##STR3## in which: X is S or SO.sub.2 and Z is hydrogen, chlorine or C.sub.1 -C.sub.5 -alkyl or C.sub.1 -C.sub.5 -alkoxy;R' is C.sub.1 -C.sub.5 -alkyl, andAr' represents ##STR4## in which: R'.sub.1 is C.sub.1 -C.sub.5 -alkyl andR'.sub.2 is hydrogen or C.sub.1 -C.sub.4 -alkyl; and moreover when R is ##STR5## Ar' may be ##STR6## in which Y is C.sub.1 -C.sub.5 alkoxy andY' is hydrogen or C.sub.1 -C.sub.

Abstract: An indoline derivative of the formula (I) ##STR1## in which R.sup.1 denotes H or C.sub.1 -C.sub.8 -alkyl;R.sup.2 and R.sup.3 are identical or different and denote C.sub.1 -C.sub.8 -alkyl;R.sup.4 -R.sup.9 are identical or different and denote H, C.sub.1 -C.sub.8 -alkyl, C.sub.5 -C.sub.6 -cycloalkyl or phenyl-C.sub.1 -C.sub.4 -alkyl, or R.sup.5 and R.sup.6 connected together to form a further C.sub.5 -C.sub.6 ring, andR.sup.10 denotes H or one or more radicals selected from the group consisting of C.sub.1 -C.sub.8 -alkyl, C.sub.1 -C.sub.8 alkoxy, C.sub.5 -C.sub.6 -cycloalkyl, phenyl-C.sub.1 -C.sub.4 -alkyl and carb-C.sub.1 -C.sub.8 -alkoxy radicals, or halogen atoms. Such indoline derivative is useful as a UV absorber.

Abstract: This invention relates to new chemical compounds possessing valuable pharmaceutical activity, particularly as lipoxygenase inhibitors possessing anti-inflammatory and anti-allergic properties.

Abstract: 5-Methyltetrazole can be produced by reacting acetonitrile with an alkali azide or ammonium azide in high purity and a yield of above 98% by using a trialkyl amine as the solvent or suspension agent and by using the associated hydrochloride of the amine as the catalyst.

Abstract: Compositions comprising(a) a pyrrolopyrrole of formula I ##STR1## wherein A and B are identical or different alkyl, aralkyl, aryl or heterocyclic aromatic radicals, R.sub.1 and R.sub.2 are hydrogen atoms, unsubstituted or substituted alkyl radicals, and also alkenyl, alkynyl, aralkyl, cycloalkyl, carbamoyl, alkylcarbamoyl, arylcarbamoyl, alkoxycarbonyl, aryl, alkanoyl or aroyl groups, and X is an --O-- or --S-- atom, and(b) a pyrrolopyrrole of the above formula I that contains at least one group of formula --SO.sub.3 L, --CO.sub.2 L, --PO.sub.3 (L).sub.2, --N(R.sub.4)(R.sub.5 ), ##STR2## oder --NHCOR wherein L is --H, a group of formula M.sub.n.sup.+n or N.sup.+ H(R.sub.3)(R.sub.4)(R.sub.5), M is a monovalent, divalent or trivalent metal cation, n is 1, 2 or 3, R.sub.3 R.sub.4 and R.sub.5 are each independently --H or alkyl, aralkyl, C.sub.5 -C.sub.6 cycloalkyl or aryl radicals, or R.sub.4 and R.sub.

Abstract: Process for the production of 4-alkoxy-3-pyrrolin-2-ones, which are preferred intermediate products for the production of cerebrally-active pharmaceutical products.