Abstract: The present invention concerns a method for determining the concentration of cationic polymers present in a sample, according to the following steps: —bringing the cationic polymer or polymers present in the sample into contact with, and enabling the interaction thereof with, a developer solution comprising lanthanide (III) ions and at least one bonding agent, and —exciting the sample at an excitation wavelength ?exc and detecting, by time resolved photoluminescence, a signal originating from the lanthanide (III) ions having interacted with the at least one bonding agent having previously interacted with the cationic polymer or polymers, at an emission wavelength ?em, and —determining the cationic polymer concentration of the sample by using the signal detected at the emission wavelength ?em, the sample originating from water originating from municipal or industrial water or sludge treatment processes.

Abstract: The invention relates to a detection system for an electronic nose capable of detecting and identifying a set of compounds that can be found in a gaseous sample, the detection system comprises a plurality of cross-reactivity detection sensors (D1, D2, D3, D4, D5, D6, D7) for supplying signals representing the presence of one or more compounds of said set in the gaseous sample, and which is particularly characterised in that the detection system further comprises at least one reference sensor (RI) for supplying a signal representing the measurement noise of the detection system. The detection system further relates to an electronic nose comprising such a detection system.

Abstract: The present invention relates to a method for determining the anionic charge density of at least one polymer present in a sample, according to the following steps: bringing the at least one polymer present in the sample into contact with, and enabling the interaction thereof with, a developer solution comprising lanthanide (III) ions, exciting the sample at an excitation wavelength ?exc and detecting, by time-resolved photoluminescence, a signal originating from the lanthanide (III) ions that have interacted with the at least one polymer at an emission wavelength ?em, and determining the anionic charge density of the at least one polymer of the sample using the signal detected at the emission wavelength ?em.

Abstract: The present invention is one that intends to achieve improvements in both analysis efficiency and analysis accuracy without difficulty, and a biological substance analysis device that analyzes light derived from a biological substance in a sample, and the biological substance analysis device includes: a holder that holds multiple containers containing the sample; a photodetector that is fixed at a predetermined position; a holder driving mechanism that moves the holder to position each of the containers held in the holder at a detection position by the photodetector in sequence; and a light shielding mechanism that, while guiding light emitted from the sample in a container at the detection position to the photodetector, prevents light emitted from the sample in the other containers from being guided to the photodetector.

Abstract: An oxygen content sensor includes a nanoparticle, a plurality of linkers, and a plurality of fluorescent molecules. The linkers are disposed on the nanoparticle. The fluorescent molecules are arranged on the linkers. The linker has at least a hydrophilic region as well as a hydrophobic region. The linker is linked to the nanoparticle through the hydrophilic region, and the fluorescent molecule is linked to the linker through the hydrophobic region.

Abstract: Provided are a rapid detection method for a condition of landfill leachate polluting groundwater and an application thereof. The rapid detection method includes: carrying out fluorescence detection on groundwater in a specific region of a landfill, and determining whether the groundwater is polluted according to a ratio of fluorescence intensities at specific excitation/emission wavelengths in a specific fluorescence region. The rapid detection method provided by the solution establishes characteristic fluorescence spectrum regions, fluorescence intensities and regular characteristics thereof of organic matters in leachate-polluted groundwater of a landfill in a fluorescence spectrum region, and can achieve the rapid detection of a condition of landfill leachate polluting groundwater by means of a portable fluorescence detector on site. The detection method provided by the solution is characterized by rapid detection, no need of chemical reagents, simple operation, high detection sensitivity and lower cost.

Abstract: Systems and methods for producing a calibration standard for an optical analysis system (e.g., a diagnostic reader) from a live test sample are disclosed. The calibration standard may include an image reproduced on a substrate. The reproduced image may be a replication of a digital image of a live test sample captured using the optical analysis system and then digitally processed to be reproduced on the substrate. The image reproduced on the substrate may include at least one optical feature digitally added to the replication of the digital image of the live test sample. The added optical features may be used to allow for more robust calibration using the calibration standard.

Abstract: A device for monitoring the spatial and temporal dynamics of thrombin that includes a temperature-controlled sealed chamber with a transparent window and a light trap, the chamber being filled with a fluid medium and designed to accommodate a cuvette containing a test sample of blood plasma, and a coagulation activating insert placed into the cuvette, at least one illumination source and at least one first irradiation source and at least one second irradiation source capable of exciting a fluorescence signal of a special marker that forms in the sample during cleavage of a fluorogenic substrate, a camera, a pressure adjustment element capable of maintaining a pressure inside the chamber, the at least one first irradiation source provides irradiation of the sample in a direction perpendicular to the cuvette, and the at least one second irradiation source provides irradiation of the sample at an angle to the cuvette.

Abstract: The present technology provides an irradiation method, a biological substance analysis method, and a biological substance analyzer to improve a throughput while securing signal reliability of detection data when a biological substance is caught on a substrate and the biological substance is detected by irradiating the substrate. For this, the present technology provides a biological substance analysis method and the like including: a step of segmenting a substrate on which a molecule that can be bound to a biological substance is immobilized and the biological substance is bound to the molecule, and irradiating the substrate in accordance with an irradiation pattern having a different segment with time; and a step of analyzing the biological substance on the basis of information obtained from the irradiation.

Abstract: Disclosed is a method of preparing a carbon quantum dot from soybean dregs by hydrothermal synthesis, including: mixing the soybean dregs with water, and subjecting the reaction mixture under heating at 100-500° C. in an autoclave for reaction; cooling the reaction mixture when the reaction is completed, and removing insoluble substances from the reaction mixture; and dialyzing the reaction mixture, and lyophilizing the dialyzed product to produce the carbon quantum dot. The invention further provides the carbon quantum dot prepared by the above method and a use thereof in the detection of Fe3+ and Hg2+ in water, where the lowest detection limit can reach 30 nmol/L and the detection range is 0.1-50 ?mol/L.

Abstract: The present disclosure provides a microfluidic chip, a device and a method for chemiluminescence immunoassay. The microfluidic chip includes a base plate, as well as a first liquid inlet channel, a second liquid inlet channel, a third liquid inlet channel, an immune reaction cell, and a luminescent reaction cell formed on a first surface of the base plate. An outlet end of the immune reaction cell is in communication with a liquid inlet end of the luminescent reaction cell, and a primer is disposed in the immune reaction cell for immobilizing an antigen-antibody complex generated in the immune reaction cell.

Abstract: A cartridge for sample handling and sensing includes (i) a sample port; (ii) a first fluid port connected to the sample reservoir in the distal region via a first fluid channel; and (iii) a second fluid port connected to the sample reservoir via a second fluid channel. The cartridge includes (i) a sensor platform comprising a bulk acoustic wave (BAW) resonator and a fluid flow path comprising a sensing region extending across a sensing surface of the BAW resonator; and (ii) a fluid valve between the sample reservoir and the sensing region. A sample may be applied to the sample port; first volume of fluid may be injected through the first fluid port; and then a second volume of fluid may be injected through the second fluid port to drive the sample into the sensing region of the fluid flow path.

Abstract: Provided are chemosensor compounds of formula (I) useful for detecting an ion, such as Pb2+ in an aqueous sample. Also provided are a chemosensor device including such compounds and methods of use thereof.

Abstract: Disclosed is a kit for detecting content of fluoride ions in a microsample, including: at least one 96-well plate, reagent A, reagent B, reagent C, reagent D, reagent E and a fluoride standard solution having a concentration of 2.5 mg/L. The kit can be used to effectively overcome the uncertainties in the existing methods for detecting fluoride ions, and also involves rapid and convenient operation. Moreover, this method involves simple and rapid operation, the use of a small amount of a sample and simultaneous detection of multiple samples. This kit provides a more standardized detection to lower the human error, thereby allowing for a more reliable result and for a suitable application in the on-site detection of content of fluoride ions in various environments such as in water quality engineering or in the laboratory.

Abstract: A device for capturing biological particles in suspension in a liquid medium. The device includes a container that is open via a lower opening, and a filter membrane fixed on the container in such a way as to close the lower opening. Inside the container are: a buffer made of a porous foam and having a planar face resting on the filter membrane, an absorbent block resting on the buffer and able to absorb the liquid medium when it is in contact with the liquid medium, and a spring designed to impede the expansion and/or movement of the absorbent block away from the lower opening of the container. Also, methods for capturing biological particles in suspension in a liquid medium using a capture device, and preparation a sample intended for biological analysis. Further an analysis apparatus that has a capture device.

Abstract: A self-adhesive layered septum is disclosed. In one example, the septum includes a first outer layer including a thermoplastic elastomer such as a styrenic block copolymer, containing styrene ethylene butylene styrene (TPE-SEBS) capable of closing at least partially an aperture formed when a needle is inserted through the layer; an adhesive second layer for adhering the septum to a mouth area of a well or container to which the septum is attachable; and a thermoplastic third layer between the first and second layers, thermobonded to the first layer and providing better adherence for the adhesive layer. The first layer includes a recess and a vent, which reduce pressure differentials in use, but together with the third layer minimize evaporation through the septum.

Abstract: Provided herein are sulfo n-hydroxysuccimidyl ester (sulfo-SE) linked peptides, methods of synthesis thereof, and methods of using such peptides for labeling of biomolecules. In particular, peptides comprising non-alkyl group such as serine, threonine, cysteine, tyrosine, glutamic acid, and aspartic acid are stably modified (e.g., without autoreactivity) with a sulfo-SE group and used to label or otherwise modify biomolecules.

Abstract: An apparatus, system, and method for performing an efficient luminescence measurement are disclosed. The apparatus comprises a nozzle for dispensing a luminescent reagent into a well W in a microplate M, a luminescence measurement unit for measuring luminescence occurring in the well W caused by mixing of the luminescent reagent and a specimen, and a stage (moving unit) for moving the nozzle and the luminescence measurement unit together vertically and horizontally, wherein the nozzle is secured to the stage and the luminescence measurement unit is mounted to be movable vertically with respect to the stage through a holder and springs interposed between the luminescence measurement unit and the holder.

Abstract: One embodiment provides a method of automatically aligning an indexing machine with a robotic end effector including: inserting, using a robotic arm, a hunting tool into an aperture, the hunting tool comprising a pressure sensitive tip; detecting, using a plurality of sensing beams, a first location of the hunting tool within the aperture; rotating, using the robotic arm, the hunting tool 180 degrees; detecting, using the plurality of sensing beams, a second location of the hunting tool within the aperture; calculating a runout magnitude and a runout direction based on the first location, the second location, and the robotic arm; inserting, using the robotic arm, the hunting tool into a target; determining, using the pressure sensitive tip, a location of the hunting tool with respect to the target; and thereafter, adjusting the location of the hunting tool with respect to the aperture and target based on said determined location and said calculated runout magnitude and direction.

Abstract: The invention relates to a biopsy container, a biopsy device, an imaging system, and a method for processing images of a biopsy container. The biopsy container comprises a container orientation mark and an alignment mark. The container orientation mark is configured for a cooperation with a corresponding shaft orientation mark arranged on a tube shaft of a biopsy device to indicate a specific orientation of the biopsy container relative to the tube shaft. The alignment mark is configured for a registration of images of the biopsy container.