Abstract: A blood pressure measurement device having an attach portion including: an opening portion provided at a position opposite a region where one artery of a wrist is found and an end surface that curves conforming to a shape in a circumferential direction of a portion of the wrist; a fastener on the attach portion; and a sensing body including: a sensor unit opposite the opening portion, the sensor unit including a sensor module that comes into contact with the region where the one artery of the wrist is found and an air bag that presses the sensor module toward the wrist by expanding when the device is worn on the wrist, a case that houses the sensor module to allow the sensor module to move in one direction with respect to the opening portion, and a biasing member that biases the sensor module in a direction away from the wrist.

Abstract: An acoustic sensor attached to a medical patient can non-invasively detect acoustic vibrations indicative of physiological parameters of the medical patient and produce an acoustic signal corresponding to the acoustic vibrations. The acoustic signal can be integrated one or more times with respect to time, and a physiological monitoring system can determine pulse or respiration parameters based on the integrated acoustic signal. The physiological monitoring system can, for instance, estimate a pulse rate according to pulses in the integrated acoustic signal and a respiration rate according to a modulation of the integrated acoustic signal, among other parameters. Further, the physiological monitoring system can compare the integrated acoustic signal or parameters determined based on the integrated acoustic signal with other signals or parameters to activate alarms.

Abstract: The present invention relates to an intraocular pressure measuring and/or monitoring device (1) comprising a contact lens (10) presenting an inner surface (101) and an outer surface (102), and a pressure sensor (2) united with said contact lens (10) and located such that it is applied against an eye (8) of a user for sensing the intraocular pressure (IOP) of said eye (8) when said contact lens (10) is worn by said user, characterized in that said contact lens (10) comprises a soft portion (11) and a rigid portion (12), said rigid portion (12) being adapted to at least partially rigidify a central portion of the inner surface (101) of said contact lens (10) so as to maintain said rigidified inner surface (101) with a curvature radius adapted to flatten at least a portion of the eye surface in contact with the pressure sensor (2) so as to reach a pressure equilibrium around the pressure sensor (2) when said contact lens (10) is worn by said user.

Abstract: Proposed are concepts of identifying physiological stress of a user of a virtual reality environment by displaying to the user a virtual object at an object location within the virtual reality environment and instructing the user to interact with the displayed virtual object. A measure of physiological stress may then be determined based on a detected parameter of the user's movement in response to the instruction, and the measure of physiological stress may be associated with a part of the user's body based on the object location.

Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

Abstract: A sample collection device collects Volatile Organic Compounds (VOCs) in exhaled breath in the outlet of a breathing assisted ventilator. The sample collection device is attached to the ventilator outlet line through a coupler containing either two check valves, or a check valve and a restrictive outlet flow path. During sampling, the exhaled air flows through a sorbent contained in the sample collection device as the ventilator pressure increases and decreases during the assisted breathing process. The flow of the exhaled air through the sample collection system is driven by the alternating pressure in the ventilator line without the need for an additional pump or power supply separate from the ventilator pump and power supply. The sample collection device can be used to monitor levels of bacteria-produced VOCs as an early detection of pneumonia and to allow feedback on the effectiveness of antibiotic treatment.

Abstract: A flowmeter has a disposable flow tube and a part of the shutter which are in direct contact with exhaled air and protect the rest of the device from potential contamination with harmful viruses.

Abstract: Sensors are disclosed that detect whether a cannula is properly inserted to its full depth in a subject's skin. The sensors may be used with a blood glucose monitor, or with a continuous insulin infusion pump, infusion set, or other system involving intermittent or continuous testing and/or drug delivery.

Abstract: A positioning method of functional rotation center of shoulder based on rigid upper arm model includes: step 1: abstracting a human upper arm into a cylinder with FRCS as a center of top surface; step 2: determining a reference axis vector of the cylinder; step 3: determining an axis vector of the cylinder and a displacement from the reference axis vector to the axis vector; step 4: correcting a central axis direction of the cylinder; step 5: determining a height compensation of the cylinder, and positioning the FRCS. The method has higher accuracy for the positioning result of FRCS, the positioning result of FRCS has better stability relative to the upper arm and trunk, and can be used to establish a more accurate human digital dynamic model and predict more accurate human posture.

Abstract: The present invention relates to a method and apparatus for measuring breath alcohol concentration of a user. A flow of an expired breath sample is passed through a fuel cell sensor giving an output signal proportional to the amount of alcohol present in the breath sample. By measuring the flow rate, the volume of the breath sample may be calculated, whereas the breath alcohol concentration is calculated based on the fuel cell output signal. Both the sample volume and the breath alcohol concentration values are continually updated by integrating the measured instantaneous flow rate and the fuel cell output signal over time. If the user stops blowing, flow compensation is performed to obtain a compensated fuel cell output signal using a stored calibration volume. Hence, an improved method for accurately measuring the breath alcohol concentration of a test person is achieved, capable of handling varied expired volumes of breath, which obviates the need for a sampling mechanism.

Abstract: A real-time motion capture system and garment includes a wearable activity monitor that may be a pair of denim jeans. The wearable activity monitor includes multiple sensors such as accelerometers, gyrometers, magnetometers disposed within the seams of the garment. A microprocessor and wireless transmitter) communicate the motion data to an external device. The microprocessor and wireless transmitter may be included within one of the seams. An elastically stretchable ribbon or a flexible ribbon such as a kapton ribbon or a ribbon formed of textile, electrically couples the sensors and microprocessor and is also disposed inside the seams and the components within the seam are coated with a waterproof coating. The external device can store the data or display and analyze the data real-time, and may communicate the data to a further electronic device.

Abstract: The present invention relates to a brain dysfunction and seizure detector monitor and system, and a method of detecting brain dysfunction and/or seizure of a subject. Preferably, the present invention also includes one or more seizure detection algorithms. The analysis method is specifically optimized to amplify abnormal brain activity and minimize normal background activity yielding a seizure index directly related to the current presence of ictal activity in the signal. Additionally, a seizure probability index based on historical values of the aforementioned seizure index, is derived for diagnostic purposes. The seizure probability index quantifies the probability that the patient has exhibited abnormal brain activity since the beginning of the recording. These indexes can be used in the context of emergency and/or clinical situations to assess the status and well-being of a patient's brain, or can be used to automatically administer treatment to stop the seizure before clinical signs appear.

Abstract: Methods, systems, and devices for measuring respiratory parameters from an ECG device are described. The method may include receiving an electrocardiogram (ECG) signal associated with a patient. The method may further include detecting a change in modulation of the ECG signal between a first portion of the ECG signal and a second portion of the ECG signal. The method may further include determining a change in respiratory effort of the patient based at least in part on the change in modulation.

Abstract: An electrocardiogram measurement system includes a patch-type electrocardiogram measurement apparatus; a first device connected to the electrocardiogram measurement apparatus by means of a first communication and configured to store electrocardiogram data measured by the electrocardiogram measurement apparatus; and a second device connected to the electrocardiogram measurement apparatus by means of the first communication and configured to store electrocardiogram data measured by the electrocardiogram measurement apparatus. The electrocardiogram data measured by the electrocardiogram measurement apparatus includes measured time information.

Abstract: Systems and methods for monitoring patients with respiratory diseases are described. A system may include a sensor circuit configured to sense one or more physiological signals indicative of respiratory sounds, and a spectral analyzer to generate first and second spectral contents at respective first and second frequency bands. The system may produce a respiratory anomaly indicator using the first and second spectral contents, or additionally with other physiological parameters. The system may detect an onset or progression of a target respiratory condition such as asthma or chronic obstructive pulmonary disease using the respiratory anomaly indicator, or to trigger or adjust a therapy.

Abstract: Techniques for determining a volume of exhaled CO2 as a function of time using side-stream capnography, including obtaining flow dynamics measurements of a subject from a flow sensor; obtaining CO2 concentration measurements of the subject from a side-stream CO2 monitor; determining a duration of time (?Ts1) for a sample of gas to flow from a reference point to the side-stream CO2 monitor; synchronizing in time the CO2 concentration measurement with the flow dynamics measurement, based on the determined ?Ts1; and determining a volume of CO2 exhaled as a function of time, based on the flow dynamics measurement and the synchronized CO2 concentration measurement.

Abstract: Embodiments of the present disclosure provide respiration monitoring systems and methods for using same. The respiration monitoring device can include a first accelerometer, a second accelerometer, at least one acoustic sensor, a memory comprising a lookup table, a real-time clock, and one or more instructions, and a processor for receiving one or more motion signals from each accelerometer and one or more sound signals from each acoustic sensor. The processor can correlate the one or more motion signals to a distance value, correlate the one or more sound signals to a sound value, filter the distance value and the sound value according to limitations stored in the lookup table, assign a time stamp to each filtered value, determine local maximums for the filtered motion values and local minimums for the filtered sound values, and match the local maximums to the local minimums to confirm a completed breath.

Abstract: Bending stresses experienced by a pressure sensor mounted to a fractional flow reserve catheter when tracking the catheter through the vasculature creates a distortion of the sensor resulting in an incorrect pressure reading or bend error. In order to isolate the sensor from bending stresses, the sensor is mounted with one end coupled to the distal end of the shaft while the other end of the sensor is not coupled to the catheter so that a portion of the sensor is spaced apart from the distal end of the shaft.

Abstract: This invention is a dry EEG electrode with an articulated distal base and/or a plurality of articulated conductive proximal protrusions which penetrate between strands of hair for good electromagnetic contact without causing discomfort or skin irritation.

Abstract: Transdermal microneedles continuous monitoring system is provided. The continuous system monitoring includes a substrate, a microneedle unit, a signal processing unit and a power supply unit. The microneedle unit at least comprises a first microneedle set used as a working electrode and a second microneedle set used as a reference electrode, the first and second microneedle sets arranging on the substrate. Each microneedle set comprises at least a microneedle. The first microneedle set comprises at least a sheet having a through hole on which a barbule forms at the edge. One of the sheets provides the through hole from which the barbules at the edge of the other sheets go through, and the barbules are disposed separately.