Patents Examined by Jacqueline Cheng
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Patent number: 11253176Abstract: A single, optimal, fused sensor glucose value may be calculated based on respective sensor glucose values of a plurality of redundant working electrodes (WEs) of a glucose sensor. Respective electrochemical impedance spectroscopy (EIS) procedures may be performed for each of the WEs to obtain values of membrane resistance (Rmem) for each WE. A noise value and a calibration factor (CF) value may be calculated for each WE, and respective fusion weights may be calculated for Rmem, noise, and CF for each WE. An overall fusion weight may then be calculated based on the WE's Rmem fusion weight, noise fusion weight, and CF fusion weight, such that a single, optimal, fused sensor glucose value may be calculated based on the respective overall fusion weight and sensor glucose value of each of the plurality of redundant working electrodes.Type: GrantFiled: May 30, 2019Date of Patent: February 22, 2022Assignee: MEDTRONIC MINIMED, INC.Inventors: Andrea Varsavsky, Yunfeng Lu, Jay Mung
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Patent number: 11253177Abstract: A sensor assembly for detecting at least one analyte in a body fluid includes an electrochemical sensor, a body mount that attaches to a body of a user and an inserter that transfers the sensor to the body mount. A first adhesive is attached to one or both of the body mount or the sensor, and the first adhesive attaches the sensor to the body mount. A second adhesive is attached to one or both of the sensor or the inserter and releasably attaches the sensor to the inserter. The assembly has an initial position in which the sensor is attached to the inserter via the second adhesive and a final position in which the sensor is attached to the body mount via the first adhesive. Transferring the sensor from the initial position to the final position releases the sensor from the inserter.Type: GrantFiled: May 17, 2018Date of Patent: February 22, 2022Assignee: Roche Diabetes Care, Inc.Inventors: Herbert Harttig, Oliver Kube, Michael Orth, Helmut Walter
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Patent number: 11253192Abstract: A handheld, conforming capacitive sensing apparatus configured to measure Sub-Epidermal Moisture (SEM) as a mean to detect and monitor the formation of pressure ulcers. The device incorporates an array of electrodes which are excited to measure and scan SEM in a programmable and multiplexed manner by a battery-less RF-powered chip. The scanning operation is initiated by an interrogator which excites a coil embedded in the apparatus and provides the needed energy burst to support the scanning/reading operation. Each electrode measures the equivalent sub-epidermal capacitance corresponding and representing the moisture content.Type: GrantFiled: December 5, 2018Date of Patent: February 22, 2022Assignees: Bruain Biometrics, LLC, The Regents of the University of CaliforniaInventors: Majid Sarrafzadeh, William Kaiser, Alireza Mehrnia, Barbara M. Bates-Jensen, Frank Wang, Michael Flesch, Joseph Boystak, Yeung Lam
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Patent number: 11246495Abstract: Various embodiments are described herein for a system and a method for monitoring aortic pulse wave velocity and blood pressure. A pulse sensor is located on the exterior of an individual's body at a sensor location that allows acquisition of the pulse signal such that a reflected wave component of the pulse signal is present and allows characterization of reflected wave onset. A pulse signal is received from the pulse sensor and a reflected wave onset point is identified in the pulse signal. A reflected wave ratio is determined at the reflected wave onset point and the aortic pulse wave velocity is determined from the reflected wave ratio. The aortic pulse wave velocity can be displayed to the individual, transmitted to an external device and/or stored.Type: GrantFiled: October 27, 2015Date of Patent: February 15, 2022Assignee: Vital Sines International Inc.Inventors: Jesse Goodman, Benoit Lewden
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Patent number: 11241186Abstract: There is provided a method for simulating at least one wet electroencephalogram (EEG) signal from at least one dry EEG signals, comprising: receiving at least one dry EEG signal measured by dry EEG electrode(s) applied to locations on a head of a patient corresponding to at least one of temporal lobe or frontal lobe, computing at least one simulated wet EEG signal by applying a trained statistical model based on at least one dry EEG signal, the at least one simulated wet EEG signal simulating wet EEG signals measured by a wet EEG electrode applied to at least one location corresponding to at least one of: central, parietal lobe, and occipital lobe, and providing the at least one simulated wet EEG signal for adjusting feedback of a neurofeedback treatment applied by a neurofeedback device.Type: GrantFiled: January 3, 2018Date of Patent: February 8, 2022Assignee: Myndlift Ltd.Inventors: Aziz Kaddan, Anas Abu Mukh, Shiri Simon
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Patent number: 11241166Abstract: A body-mountable device is provided to facilitate communication, via in-body electrical signals transmitted via electrodes of the body-mountable device into fluid of the body, with a smart pill located in a gastrointestinal tract of a body to which the body-mountable device is mounted or with some other device located within the body. The body-mountable device can be a contact lens or other eye-mountable device such that the electrodes of the eye-mountable device can transmit in-body electrical signals via tear fluid. The body-mountable device could transmit a command to the smart pill to dispense a drug into the body. The smart pill could transmit, via in-body electrical signals, an indication of a detected property of the gastrointestinal tract to the body-mountable device. A latency of transmission of signals between the body-mountable device and the smart pill could be used to determine the location of the smart pill within the gastrointestinal tract.Type: GrantFiled: December 29, 2016Date of Patent: February 8, 2022Assignee: Verily Life Sciences, LLCInventor: Shungneng Lee
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Patent number: 11234613Abstract: There is provided a respiration estimation method. The respiration estimation method includes a first step (S107) of estimating a breathing rate of a subject based on each of a time-series signal of first data relating to a cardiac function of the subject and a time-series signal of second data relating to an acceleration by a respiratory motion of the subject, a second step (S108) of estimating a breathing rate obtained by filtering noise using a Kalman filter for each of the breathing rate estimated based on the first data and the breathing rate estimated based on the second data, and a third step (S109) of executing weighted averaging processing for the plurality of estimated values of the breathing rates obtained in the second step.Type: GrantFiled: November 25, 2016Date of Patent: February 1, 2022Assignee: NIPPON TELEGRAPH AND TELEPHONE CORPORATIONInventors: Takayuki Ogasawara, Takurou Tajima, Kei Kuwabara, Nobuaki Matsuura, Ryoichi Kasahara
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Patent number: 11229423Abstract: A tissue collecting instrument which cuts and collects tissue includes a first member formed in a tubular shape and including an internal space and a side hole communicating with the internal space, a second member inserted into the internal space and configured to be movable relative to the first member, a first protruding portion provided on the first member and configured to protrude toward the inside of the side hole, and a second protruding portion provided on the second member and configured to protrude in a direction opposite to the first protruding portion, wherein the tissue is able to enter the internal space through the side hole when the first member and the second member are in a positional relationship in which the first protruding portion and the second protruding portion are spaced apart and facing each other.Type: GrantFiled: April 25, 2017Date of Patent: January 25, 2022Assignee: NANO GRAINS CO., LTD.Inventor: Keita Suzuki
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Patent number: 11219379Abstract: Systems for monitoring left atrial pressure using implantable cardiac monitoring devices and, more specifically, to a left atrial pressure sensor implanted through a septal wall are presented herein.Type: GrantFiled: September 10, 2018Date of Patent: January 11, 2022Assignee: PACESETTER, INC.Inventors: Phong D. Doan, Apratim Dixit
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Patent number: 11213222Abstract: A method and apparatus to determine residual long volume of a subject is disclosed. Physical characteristics of water in a pool and surrounding air barometric pressure is determined. A body of the subject is completely submerged in the pool of water at a known depth and exhales. The subject then moves to a shallower depth in the water and completely exhales air into an air measuring device. The residual lung volume is then determined and displayed based on the water characteristics, barometric air pressure, the amount of air exhaled into the air measuring device, and the depths of the subject during exhalation.Type: GrantFiled: October 23, 2018Date of Patent: January 4, 2022Assignee: PhysicsIP, Inc.Inventor: Sterling L Cannon
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Patent number: 11191441Abstract: Respiratory variables are estimated on a per-breath basis from airway pressure and flow data acquired by airway pressure and flow sensors (20, 22). A breath detector (28) detects a breath interval. A per-breath respiratory variables estimator (30) fits the airway pressure and flow data over the detected breath interval to an equation of motion of the lungs relating airway pressure, airway flow, and a single-breath parameterized respiratory muscle pressure profile (40, 42) to generate optimized parameter values for the single-breath parameterized respiratory muscle pressure profile. Respiratory muscle pressure is estimated as a function of time over the detected breath interval as the single-breath parameterized respiratory muscle pressure profile with the optimized parameter values, and may for example be displayed as a trend line on a display device (26, 36) or integrated (32) to generate Work of Breathing (WoB) for use in adjusting settings of a ventilator (10).Type: GrantFiled: September 18, 2016Date of Patent: December 7, 2021Assignee: Koninklijke Philips N.V.Inventors: Francesco Vicario, Antonio Albanese, Dong Wang, Nikolaos Karamolegkos, Nicolas Wadih Chbat
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Patent number: 11179050Abstract: Most automatic cuff blood pressure (BP) measurement devices are based on oscillometry. These devices estimate BP from the envelopes of the cuff pressure oscillations using fixed ratios. The values of the fixed ratios represent population averages, so the devices may be accurate only in subjects with normal BP levels. A patient-specific oscillometric BP measurement method was developed. The idea was to represent the cuff pressure oscillation envelopes with a physiologic model and then estimate the patient-specific parameters of the model, which includes BP levels, by optimally fitting it to the envelopes.Type: GrantFiled: September 9, 2016Date of Patent: November 23, 2021Assignees: Board of Trustees of Michigan State University, University of Maryland, College ParkInventors: Jiankun Liu, Mohsen Moslehpour, Jin-Oh Hahn, Ramakrishna Mukkamala
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Patent number: 11179143Abstract: The present disclosure generally relates to devices, systems, and methods for Fallopian tube diagnostics. In some embodiments a tube may have a distal end, and a balloon may have a first end coupled to the distal end of the tube. The balloon may be disposed in the tube in a first, inverted position, may be movable to a second, everted position, and may be extendable a distance distal of the tube. An extending portion may have a proximal end coupled to a second end of the balloon. The extending portion may be disposed within the balloon in the first inverted position, and may be extendable from the second end of the balloon in the second everted position.Type: GrantFiled: August 16, 2018Date of Patent: November 23, 2021Assignee: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Jesus Magana, David W. Snow, Alan L. Bradley, Christina Christman-Skieller, Surbhi Sama
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Patent number: 11172859Abstract: This invention is a wearable brain activity device with electrodes held on a person's head by a frame comprising a ring portion which encircles the person's head and an arc portion which loops over the top of the person's head. Data from the electrodes is used to analyze the person's brain activity within a frequency band of 0.5-4 Hz. The device includes a speaker or vibrating member which is used to help to guide the person's brain activity from a first pattern to a second pattern.Type: GrantFiled: June 29, 2018Date of Patent: November 16, 2021Assignee: MediboticsInventor: Robert A. Connor
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Patent number: 11166650Abstract: A medical device and method for determining a dose of insulin to be administered for glycemic control is provided, wherein the dose is stepwise adapted. The method includes determining a blood glucose value, receiving glycemic event information in respect to a predetermined glycemic event, wherein the predetermined glycemic event occurred within a predetermined time interval, receiving a previously adapted dose value stored in a storage unit, and setting an alert based on at least the blood glucose value, the glycemic event information and the previously adapted dose, wherein the alert indicates that the blood glucose value and the predetermined glycemic event are not in a specified relation to the previously adapted dose value.Type: GrantFiled: February 3, 2010Date of Patent: November 9, 2021Assignee: Sanofi-Aventis Deutschland GmbHInventor: Andrew Tubb
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Patent number: 11166655Abstract: This disclosure relates to a glucose-sensing electrode including a nanoporous metal layer and an electrolyte ion-blocking layer formed over the nanoporous metal layer. The nanoporous metal layer is capable of oxidizing both glucose and maltose without an enzyme specific to glucose in the glucose-sensing electrode. The electrolyte ion-blocking layer is configured to inhibit Na+, K+, Ca2+, Cl?, PO43? and CO32? from diffusing toward the nanoporous metal layer such that there is a substantial discontinuity of a combined concentration of Na+, K+, Ca2+, Cl?, PO43? and CO32? between over and below the electrolyte ion-blocking layer.Type: GrantFiled: November 19, 2018Date of Patent: November 9, 2021Assignee: UXN Co., Ltd.Inventors: Hankil Boo, Rae Kyu Chang
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Patent number: 11166799Abstract: A physiological condition determination system and method can include: attaching a tag to animal tissue; emitting light into the animal tissue; detecting a first optical signal; extracting a first measurement of peripheral capillary oxygen saturation from the first optical signal; qualifying the first measurement of peripheral capillary oxygen saturation as a baseline; detecting a second optical signal with the optical sensor; extracting a second measurement of peripheral capillary oxygen saturation from the second optical signal; qualifying the second measurement of peripheral capillary oxygen saturation; storing the second measurement of peripheral capillary oxygen saturation as a tag feature set; storing a history; determining animal distress based on the difference between the second measurement of peripheral capillary oxygen saturation and the baseline; and sending an instruction to the tag.Type: GrantFiled: May 18, 2018Date of Patent: November 9, 2021Assignee: Maxim Integrated Products, Inc.Inventors: John Philip Hanks, Ian Chen
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Patent number: 11160477Abstract: A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.Type: GrantFiled: October 25, 2018Date of Patent: November 2, 2021Assignee: MEDTRONIC MINIMED, INC.Inventors: Ning Yang, Raghavendhar Gautham, Rajiv Shah
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Patent number: 11160505Abstract: One variation of a method for testing contact quality of electrical-biosignal electrodes includes: outputting a drive signal through a driven electrode, the drive signal comprising an alternating-current component oscillating at a reference frequency and a direct-current component; reading a set of sense signals from a set of sense electrodes at a first time; calculating a first combination of the set of sense signals; calculating a first direct-current value comprising a combination of the first combination and the direct-current component of the drive signal at approximately the first time; and at a second time succeeding the first time, shifting the direct-current component of the drive signal output by the driven electrode to the first direct-current value.Type: GrantFiled: April 21, 2020Date of Patent: November 2, 2021Assignee: Zeto, Inc.Inventors: Aswin Gunasekar, Ferenc Benedek, János Kokavecz, Gabor Braun
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Patent number: 11160499Abstract: The present invention relates to a device for accurately estimating the energy expenditure of a person, in particular by which the effect of cardiovascular drift is taken into account. The device comprises an input unit (10) for obtaining a movement signal (13) representing physical activity of the person and a heart rate signal (15) representing the heart rate of the person, a cardiovascular drift determination unit (16) for determining cardiovascular drift phases (17) from said movement signal (13) and either said heart rate signal (15) and/or one or more cardiovascular drift related signals (23) carrying information on one or more of amount of sweat, weight loss, temperature rise, blood lactate concentration and physical fatigue of the person, a correction unit (18) for correcting the heart rate signal (15) generated and representing the heart rate during a cardiovascular drift phase, and an estimation unit (20) for estimating the energy expenditure of the person from the corrected heart rate signal (19).Type: GrantFiled: December 19, 2016Date of Patent: November 2, 2021Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Alberto Giovanni Bonomi, Francesco Sartor, Gabriele Papini, Erik Gosuinus Petrus Schuijers