Abstract: Systems and methods are provided for autonomous robotic surgery which is preferably integrated with autonomous-assisted intraoperative real-time single modality and/or multi-modality fusion imaging/electrophysiological diagnostics. The robotic surgery systems and methods can be integrated with autonomous-assisted intraoperative body/limb positioning, and integrated with autonomous-assisted land and unmanned aerial vehicular patient transportation.

Abstract: Devices and related methods for impinging light on tissue to induce one or more biological effects, and more particularly illumination devices and related methods for phototherapeutic light treatments in the presence of vitamins are disclosed. Biological effects may include at least one of inactivating and inhibiting growth of one or more combinations of microorganisms and pathogens, including but not limited to viruses. Phototherapeutic light treatments in the presence of vitamins may involve providing one or more vitamins in the form of a coating or film on a surface of a target tissue and irradiating the target tissue with light. By performing the phototherapeutic light treatment in the presence of vitamins, efficacy of the light treatment may be improved, thereby reducing viral loads and/or reducing doses of light received by the target tissue.

Abstract: A plurality of devices that provide examination/diagnosis and/or treatment benefits to a patient are presented. The device including a plurality of light sources that provide for the emission of light in a plurality of wavelength ranges, wherein the plurality of light sources are activated by a sensor, configured to determine a proximity of the device to a patient, to control an application of a voltage to selected one of the plurality of light sources for a predetermined time period.

Abstract: A method and surgical system including a laser source for generating a pulsed laser beam, an imaging system including a detector, shared optics configured for directing the pulsed laser beam to an object to be sampled and confocally deflecting back-reflected light from the object to the detector, a patient interface, through which the pulsed laser beam is directed, the patient interface having, a cup with a large and small opening, and a notched ring inside the cup; and a controller operatively coupled to the laser source, the imaging system and the shared optics, the controller configured to align the eye for procedure.

Abstract: The present invention relates to an oxytocin release stimulation device (10?) that can be arranged at or close to skin of a user (40). The oxytocin release stimulation device (10?) comprises a lighting unit (14?) and a control unit (16?). The control unit (16?) controls the lighting unit (14?) such that the lighting unit (14?) provides light with specific wavelengths and radiant exposures to the skin of the user (40) for a duration that ensures stimulation of a release of oxytocin. Release of oxytocin allows to stimulate a milk ejection reflex and thus to support milk extraction, e.g. when the oxytocin release stimulation device (10) is used with a breast pump (100?). The oxytocin release stimulation device (10?) can furthermore allow to reach an oxytocin level during pregnancy that allows to reduce the risk of postpartum depression or that allows to facilitate induction of labor.

Abstract: A system for measuring pain of a person, the system for use with the tissue of the person. Various sensors and detectors on the tissue provide signals to a controller for determining and indicating a pain level of the person.

Abstract: Prediction of a disease onset risk is enabled by focusing on characteristic change in biological information depending on a time period. A prediction device SV acquires blood pressure data and determination data on irregular pulse waves and acquires input data indicating a sleep time period or information indicating a determination result of a sleep condition. Further, based on the input data indicating the sleep time period or the information indicating the determination result of the sleep condition, the sleep time period is set as a prediction target period and is divided into a first half and a second half. A degree of change in the blood pressure data and a degree of change in frequency of occurrence of irregular pulse waves in each of the first half time period and the second half time period are calculated and multiplied. With this, a total risk in the sleep time period is calculated.

Abstract: The presently disclosed subject matter provides techniques for inducing collagen cross-linking in human tissue, such as cartilage, by inducing ionization of the water contained in the tissue to produce free radicals that induce chemical cross-linking in the human tissue. In an embodiment, a femtosecond laser operates at sufficiently low laser pulse energy to avoid optical breakdown of the tissue being treated. In an embodiment, the femtosecond laser operates in the infrared frequency range.

Abstract: An intravascular blood pump having a rotatable shaft carrying an impeller and a housing with an opening through which the shaft extends with the impeller positioned outside the housing. The shaft and the housing have surfaces forming a circumferential gap which has a gap width of no more than 2 ?m over at least part of the length of the gap and at least one of the surfaces forming the gap is made of a material having a thermal conductivity of at least 100 W/mK, in particular a ceramic material such as silicon carbide.

Abstract: The present disclosure concerns a sensor assembly for measuring displacement of a contact surface at least along a central axis of the assembly caused by pressure applied on the surface by the skin of a user during measurement of at least one biological parameter of the user.

Abstract: In some implementations, the device may include an optical diffuser assembly having a plurality of light emitting devices positioned along an axis adjacent to one another and the plurality of light emitting devices are adapted to be selectively addressable to produce an irradiance pattern for each of the plurality of the light emitting devices.

Abstract: An apparatus, system, and method for monitoring a person suffering from a chronic medical condition predicts and assesses physiological changes which could affect the care of that subject. Examples of such chronic diseases include (but are not limited to) heart failure, chronic obstructive pulmonary disease, asthma, and diabetes. Monitoring includes measurements of respiratory movements, which can then be analyzed for evidence of changes in respiratory rate, or for events such as hypopneas, apneas and periodic breathing. Monitoring may be augmented by the measurement of nocturnal heart rate in conjunction with respiratory monitoring. Additional physiological measurements can also be taken such as subjective symptom data, blood pressure, blood oxygen levels, and various molecular markers. Embodiments for detection of respiratory patterns and heart rate are disclosed, together with exemplar implementations of decision processes based on these measurements.

Abstract: The electrocardiogram measurement apparatus includes: two amplifiers for receiving electrocardiogram signals from a first electrode and a second electrode; one electrode driving unit; a third electrode for receiving an output of the electrode driving unit; an A/D converter connected to an output terminal of each of the two amplifiers and converting analog signals into digital signals; a microcontroller for receiving the digital signals from the A/D converter; and a communication means for transmitting the digital signal, wherein: the microcontroller is supplied with power from a battery; the microcontroller controls the A/D converter and the communication means; and each of the two amplifiers amplifies one electrocardiogram signal so as to simultaneously measure two electrocardiogram signals.

Abstract: A photodynamic therapy (PDT) apparatus and method are disclosed. The PDT apparatus includes a light flap that includes a plurality of light emitting devices wherein each of the light emitting devices has a plurality of operating states. The plurality of operating states are used to train a neural network model capable of producing a treatment irradiance profile. The method includes using an image of an area of interest for targeted treatment of PDT wherein the image is used an input to the trained neural network model. The neural network model produces a plurality of optimized feature states and the apparatus in turn produces a treatment irradiance profile closely matching the area of interest.

Abstract: Embodiments of apparatuses and methods for determining a positioning of sensors in a wound dressing are disclosed. In some embodiments, a wound monitoring and/or therapy system can include a wound dressing and a plurality of sensors configured to measure one or more wound characteristics. The wound monitor system can also include at least one positioning device configured to indicate position and/or orientation in the wound of a sensor of the plurality of sensors. In some embodiments, a detector can be configured to determine, based on the positioning data, the position and/or orientation in the wound of the sensor of the plurality of sensors. In some embodiments, the plurality of sensors can be positioned on a strip or string of material in communication with the positioning device.

Abstract: A light therapy wearable includes a fabric panel and a side-emitting light tube affixed to or held against the fabric panel. The side-emitting optical light tube includes a side-emitting optical fiber and a jacket surrounding the side-emitting optical fiber. The side-emitting optical fiber includes a core and cladding surrounding the core. The core is made from a synthetic polymeric material. The jacket is made from a transparent or translucent material and has a durometer of at least 65 A and an outer diameter at least seven times a core diameter of the side-emitting optical fiber.

Abstract: Harvested stem cells are activated by treating them with an amplitude modulated laser beam having a wavelength lying in the range of 405 to 980 nanometers. The frequency of the laser beam is modulated within a range of 8 to 12 MHz. Using the activated stem cells, tissue can be repaired and regenerated by preparing the unactivated stem cells, treating the unactivated stem cells with an amplitude modulated laser beam having a pre-determined frequency for obtaining activated stem cells, administering the activated stem cells into a body containing the tissue, and using a homing beam to guide the activated stem cells within the body to the location of the tissue.

Abstract: Systems and methods to determine if an individual is impaired. The system includes a display and a stimulus on the display. The system include a controller that is programmed to move the stimulus about the display and one or more sensors that track eye movements and pupil size of a user due to movement of the stimulus or light conditions. The system includes a processor programmed to analyze the eye movements and pupil data size. The method includes using a testing apparatus and collecting data from the testing apparatus. The method includes storing the collected data. The method includes processing the data with an automated impairment decision engine to determine whether a test subject is impaired. The method may include using machine learning models or statistical analysis to determine whether a test subject is impaired. The automated impairment decision engine may be trained using machine learning and/or statistical analysis.

Abstract: A method of treating a neurological disorder and/or disease includes positioning a stimulation apparatus on a patient. The stimulation apparatus includes an electrode array having a plurality of electrodes and an emitter array having a plurality of emitters. The method further includes measuring electroencephalography (EEG) signals of the patient with the electrode array. The method further includes emitting radiation into the patient's brain from the emitter array based on the measured EEG signals in order to treat the neurological disorder and/or disease.

Abstract: A surgical robotic system comprising: a surgical robotic arm having a plurality of robotic arm links and a plurality of joints operable to move according to multiple degrees of freedom; a proximity sensor coupled to the surgical robotic arm, the proximity sensor comprising a plurality of sensing pads operable to detect a movement of a nearby controlling object prior to contact with the surgical robotic arm; and a processor configured to determine a desired position of the surgical robotic arm based on the detected movement of the nearby controlling object and drive a movement of more than one of the plurality of robotic arm links or the plurality of joints to achieve the desired position of the surgical robotic arm.