Abstract: Harvested stem cells are activated by treating them with an amplitude modulated laser beam having a wavelength lying in the range of 405 to 980 nanometers. The frequency of the laser beam is modulated within a range of 8 to 12 MHz. Using the activated stem cells, tissue can be repaired and regenerated by preparing the unactivated stem cells, treating the unactivated stem cells with an amplitude modulated laser beam having a pre-determined frequency for obtaining activated stem cells, administering the activated stem cells into a body containing the tissue, and using a homing beam to guide the activated stem cells within the body to the location of the tissue.

Abstract: A light therapy wearable includes a fabric panel and a side-emitting light tube affixed to or held against the fabric panel. The side-emitting optical light tube includes a side-emitting optical fiber and a jacket surrounding the side-emitting optical fiber. The side-emitting optical fiber includes a core and cladding surrounding the core. The core is made from a synthetic polymeric material. The jacket is made from a transparent or translucent material and has a durometer of at least 65 A and an outer diameter at least seven times a core diameter of the side-emitting optical fiber.

Abstract: Systems and methods to determine if an individual is impaired. The system includes a display and a stimulus on the display. The system include a controller that is programmed to move the stimulus about the display and one or more sensors that track eye movements and pupil size of a user due to movement of the stimulus or light conditions. The system includes a processor programmed to analyze the eye movements and pupil data size. The method includes using a testing apparatus and collecting data from the testing apparatus. The method includes storing the collected data. The method includes processing the data with an automated impairment decision engine to determine whether a test subject is impaired. The method may include using machine learning models or statistical analysis to determine whether a test subject is impaired. The automated impairment decision engine may be trained using machine learning and/or statistical analysis.

Abstract: A system, a wearable device, and a method are provided which can increase the accuracy of physiological metrics while detecting if the patient ingested digital medicine and/or improve performance of the wearable device. The wearable device can comprise machine executable instructions that when executed by the processor, cause the processor to perform various algorithms, such as, for example, at least one of a step count algorithm, a body angle algorithm, a heart rate algorithm, a peak finder algorithm, an adaptive thresholding algorithm, a heart rate variability algorithm, a R-R cleaning Algorithm, a deltaR-R cleaning algorithm, a merge twin interval algorithm, a split tall intervals algorithm, an absorb short intervals algorithm, a bimodal detection algorithm, and a resting algorithm.

Abstract: A method of treating a neurological disorder and/or disease includes positioning a stimulation apparatus on a patient. The stimulation apparatus includes an electrode array having a plurality of electrodes and an emitter array having a plurality of emitters. The method further includes measuring electroencephalography (EEG) signals of the patient with the electrode array. The method further includes emitting radiation into the patient's brain from the emitter array based on the measured EEG signals in order to treat the neurological disorder and/or disease.

Abstract: A surgical robotic system comprising: a surgical robotic arm having a plurality of robotic arm links and a plurality of joints operable to move according to multiple degrees of freedom; a proximity sensor coupled to the surgical robotic arm, the proximity sensor comprising a plurality of sensing pads operable to detect a movement of a nearby controlling object prior to contact with the surgical robotic arm; and a processor configured to determine a desired position of the surgical robotic arm based on the detected movement of the nearby controlling object and drive a movement of more than one of the plurality of robotic arm links or the plurality of joints to achieve the desired position of the surgical robotic arm.

Abstract: The present disclosure relates generally to a system and method for detecting or indicating a state of impairment of a test subject or user due to drugs or alcohol, and more particularly to a method, system and application or software program configured to creating a virtual-reality (“VR”) environment that implements drug and alcohol impairment tests, and which utilizes eye tracking technology to detect or indicate impairment.

Abstract: A device configured to provide a faster and more accurate measurement of depths of holes for placement of bone screws and fastener for bone implant fixation procedures. The device includes a combination of a bone probe for physical examination of a hole drilled in a bone and a depth gauge member for determining a depth of the hole and providing digital measurement of the depth.

Abstract: Embodiments of the invention include a compact, lightweight, hand-held laser treatment device that combines the emissions of two separate laser energy sources into a common optical pathway for improved therapeutic effect. In some embodiments, the device includes a housing having separate first and second laser sources disposed within the interior thereof. In some embodiments, the laser energy emissions from the two internal laser sources can be individually or concurrently transmitted to a delivery tip of the device via a laser transmission path also defined within the interior of the housing. In some embodiments, the structural and functional features of the first and second laser sources, in concert with the unique architecture of the laser transmission path, can be configured to provide efficacy and efficiency in the operation of the device within the spatial constraints of the lightweight, hand-held housing thereof.

Abstract: Earphone apparatus includes dry electrophysiological electrodes and, optionally, other physiological and/or environmental sensors to measure signals such as ECG from the head of a subject. Methods of use of such apparatus to provide fitness, health, or other measured or derived, estimated, or predicted metrics are also disclosed.

Abstract: The present invention provides a personalized, three-dimensional printed, human auricle-specific multiple auricular points' bio-signal acquisition, health status monitoring, and bio-stimulation device, including an artificial ear model made of at least one bio-compatible, flexible polymer, a plurality of sensing and stimulating electrodes with at least one sensing end and a signal acquisition/processing end penetrating through a body of the ear mold conformably with a human auricle so that a surface of the ear mold where sensing end of the electrodes is disposed creates an electrode-human skin interface for bio-signal detection and bio-stimulation responsive thereto. Methods of fabricating the device based on 3-D printing, 3D scanning and modelling techniques and using thereof for bio-signal acquisition, analysis, health status monitoring and bio-stimulation are also provided.

Abstract: Methods and systems are described for detecting the likelihood of patent ductus arteriosus (PDA) in an infant using electrocardiogram and photoplethysmographic pulse signals obtained from the upper body and foot of the infant.

Abstract: A laser fiber probe comprises two parts, a suction sheath and a fiber conduit, which are combined together. The suction sheath has an opening in the distal end of the suction sheath and the opening is either completely in the side of the suction sheath, or in combination of part the terminal and the side. The fiber conduit has a fiber position regulator functioning to move forward or backward of the fiber tip to approach the suction opening. The relative position of the suction sheath and the fiber conduit of the fiber probe or is fixed, or can be changed through turning movement. The laser fiber probe further comprises a suction switcher to turn on or off the suction channel. The fiber probe has applications in calculus and tissue fragmentation and simultaneously evacuates them away out of the patient.

Abstract: An optical system for a laser therapy instrument for the application of laser radiation on and in the eye, includes a femtosecond laser, an objective. The objective or at least one lens or lens group of the objective is shiftable in the direction of the optical axis being intended for shifting of the focus position from the region of the cornea to the region of the crystalline lens and vice versa. The optical system may include at least two optical assemblies designed for the axial variation of the focus of the therapeutic laser radiation, with the focus variation range ?z differing between the individual assemblies and a changing device, designed for the insertion of any one of these assemblies into the therapeutic laser beam path at a time.

Abstract: The embodiments disclose a digitally enabled pelvic self-examination device including a first memory device to receive and store cervix images, a second memory device to receive and store heat detection sensor data, a first processor to convert the heat detection sensor data into superimposed overlays on the first memory device stored cervix images, a second processor to compare current stored cervix images to previously stored cervix images to determine any changes, an internet communication device coupled to a memory device and processor to receive an aggregation of data on disease prevalence and research, a third processor to generate a determination of any changes in the stored cervix images indicating any disease indications present including cervical cancer, a swab device configured to allow the user to collect a cervix tissue laboratory analysis sample, and a digitally enabled pelvic self-examination device configured to be used by user to perform a pelvic self-examination.

Abstract: A surgical instrument may comprise a chassis configured to be removably coupled with a surgical robotic manipulator and may comprise an elongate flexible shaft coupled to the chassis. The surgical instrument may also comprise a robotic actuation piece coupled to and rotatable relative to the chassis and a manual actuator coupled to and translatable relative to the chassis. A rack gear may be engaged with the manual actuator and with the robotic actuation piece. The rack gear may be movable by the robotic actuation piece and by the manual actuator to control an operation of the elongate flexible shaft.

Abstract: The present specification discloses a photobiomodulation therapy garment having a garment structure configured to be worn by a user atop a skin surface with one or more near-infrared light sources integrated with the garment structure. The near-infrared light source is configured to emit near-infrared light directed to one or more regions of interest of the skin at a wavelength between 600 nm to 1600 nm and at a predetermined dosimetry and duration. A controller with a processor and memory is in communication with the near-infrared light source to control the operational parameters of the near-infrared light source.

Abstract: A medical apparatus and method of operating a medical apparatus are disclosed. The apparatus includes a radiation source for emitting radiation towards an area to be treated of a patient; a mount element arranged to be worn by the patient for positioning the radiation source in a predetermined position relative to the area to be treated; a sensor element arranged to provide a signal indicative of whether the apparatus is being worn by the patient; and at least one controller arranged to receive the signal from the sensor, and to determine whether the apparatus is being worn by the patient, and to determine duration data indicative of the duration for which the radiation source emits radiation whilst the apparatus is being worn by the patient.

Abstract: A preoperative surgical planning system uses a head-mounted device to execute a preoperative surgical simulation whereby a virtual tool and a virtual anatomical model are provided on the display of the head-mounted device. The virtual tool is tracked relative to the virtual anatomical model in the preoperative surgical simulation in which the virtual tool is moveable in response to receipt of a control input from the wearer of the head-mounted device and wherein the virtual tool is configured to remove a portion of the virtual anatomical model. A planning parameter is automatically generated based on tracking of the virtual tool relative to the virtual anatomical model in the preoperative surgical simulation. The generated planning parameter is stored for future retrieval by a surgical system to facilitate intraoperative surgery based on the generated planning parameter.

Abstract: An exemplary treatment system can be provided which can include a laser system configured to emit at least one laser beam, and an optical system configured to focus the laser beam(s) to a focal region at a selected distance from a surface of a tissue. The focal region can be configured to illuminate at least a portion of a target. The optical system can cause an irradiation energy transferred to the focal region of the laser beam(s) to (i) generate a plasma in a first region of the tissue adjacent to the target, and (ii) avoid a generation of a plasma in a second region of the tissue. The optical system has a numerical aperture that is in the range of about 0.5 to about 0.9. An exemplary method can also be provided to control such treatment system.