Abstract: Apparatus (100) for training oral muscle tone, the apparatus (100) includes a mouthpiece (103) having first electrode means (132a, 132b, 133a, 133b) associated with the mouthpiece (103) and second electrode means (152a, 152b) for location exterior of the mouth of the user, electrical circuitry operatively connected to the first (132a, 132b, 133a, 133b) and second (152a, 152b) electrode means, wherein the apparatus (100) is configured to provide, in use, via the first (132a, 132b, 133a, 133b) and/or second (152a, 152b) electrode means electrical stimulation to one or more oral muscles to increase resting muscle tone and/or muscle tone during sleep, the second electrode means (152a, 152b) including a first and second electrode (152a, 152b), the first and second electrodes (152a, 152b) of the second electrode means being located or locatable lateral of a midline of the face of the user.

Abstract: A stimulation therapy system dynamically modifies therapy intensity based on measured neurotransmitter levels. In some examples, the system delivers, via an electrode implanted in a brain of a patient and stimulation circuitry, an electrical stimulus; monitors an electrical current generated by the stimulation circuitry to deliver the electrical stimulus; determines, based on the electrical current, a value representative of a concentration of dopamine in the brain of the patient; determines, based on the value representative of the concentration of dopamine, a value for one or more stimulation parameters that at least partially define electrical stimulation therapy; and delivers, via the electrode, the electrical stimulation therapy.

Abstract: The present invention relates to the medical field, in particular to the treatment of neurological disorders. More specifically the present invention relates to a nanoparticle or nanoparticles' aggregate for use in prevention or treatment of a neurological disease or at least one symptom thereof in a subject when the nanoparticle or nanoparticles' aggregate is exposed to an electric field, wherein the nanoparticle's or nanoparticles' aggregate's material is selected from a conductor material, a semiconductor material, an insulator material with a dielectric constant ?ijk equal to or above 200, and an insulator material with a dielectric constant ?ijk equal to or below 100. It further relates to compositions and kits comprising such nanoparticles and/or nanoparticles' aggregates as well as to uses thereof.

Abstract: The present invention relates to an apparatus for fractional treatment of skin tissue of a patient comprising a handpiece, at least one first electrode and at least one second electrode, arranged on a base plate for applying radio frequency energy, to at least one layer of the skin, wherein the apparatus is adapted to apply electrical energy to the skin tissue with a first pulse and a second pulse following the first pulse, with the first pulse being a low energy level pulse and the second pulse being a high energy level pulse having a higher energy level than the low energy level pulse.

Abstract: The present invention relates to a mask-shaped skin treatment device and system. The device comprises one or more coupling agent detectors configured to detect presence of coupling agent on one or more skin portions of a user and one or more heating elements configured to cause local heating of one or more skin portions of the user. The one or more heating elements are configured to cause heat selectively based on the presence of coupling agent measured by the one or more coupling agent detectors.

Abstract: Disclosed is a muscle stimulation system, comprising a wearable garment including a plurality of electrodes, and a processor; wherein the processor is configured to define one or more regions of interest (ROI) for electrode activation via a subset of the plurality of electrodes, and provide electrical muscle stimulation, via the subset of the plurality of electrodes, to the ROI.

Abstract: One aspect is a process for producing a segmented electrode, including providing a pipe made of metal having an outer side and an inner side, wherein the inner side of the pipe forms a hollow space. A support structure is arranged in the hollow space, so that the support structure mechanically stabilizes the pipe. Intermediate spaces are formed in the pipe, which define a plurality of segments in the pipe. An electrically insulating material is introduced into the intermediate spaces and thus forming electrically insulating areas, wherein a boundary layer is in each case defined between the segments and the areas. The pipe is cut so that several segmented ring-shaped electrodes are formed therefrom. The support structure is removed from the pipe.

Abstract: A catheter system includes a catheter including an elongate body having an expandable medical device coupled with a distal end thereof, and an introducer sheath assembly disposed over a proximal section of the catheter. The introducer sheath assembly includes an introducer sheath disposed over the catheter to form a gap therebetween, and a tubular plug. The introducer sheath includes an elongate body extending from a proximal end to a distal end and defining a lumen therein. The tubular plug extends through the lumen and includes an elongate body extending from a proximal end to a distal end that protrudes from the introducer sheath distal end. The plug is disposed between the catheter and the introducer sheath to occlude the gap. The plug is releasably fixed relative to the introducer sheath such that the plug is removable from the lumen to allow the expandable medical device to pass therethrough.

Abstract: An electrode (10) for transcranial current stimulation is provided. The electrode (10) comprises at least two pins (11a, 11b) for contacting the skin of a living or human being, and a current delivering unit (12) connected to the at least two pins (11a, 11b). The current delivering unit (12) is configured to estimate the corresponding range of the respective contact impedance with respect to the skin for each of the at least two pins (11a, 11b) or to analyze the corresponding level of the respective contact impedance with respect to the skin for each of the at least two pins (11a, 11b). The current delivering unit (12) is configured to distribute a desired current over all of the at least two pins (11a, 11b) or to select a set of the at least two pins (11a, 11b) for delivering a set of partial currents in order to achieve the desired current.

Abstract: A lead (1) for an active implantable medical device comprising: an elongated, biocompatible, electrically non-conductive body (3); a plurality of electrically conductive filaments (5) inside the elongated body (3) to electrically connect electrical connectors (6) to corresponding electrodes (8); and at least one elongated decoy conductor (10) inside the elongated body (3) to electromagnetically couple with the plurality of electrically conductive filaments (5), wherein the at least one decoy conductor (10) has a higher electrical resistance than the plurality of electrical conductive filaments (5) to dissipate energy from currents induced by radio frequencies.

Abstract: The invention provides personalized laser probes for use in laser systems, wherein each laser probe includes one or more characteristics tailored to a given user to thereby improve performance of and outcome of a laser treatment procedure.

Abstract: An inflow cannula for an implantable blood pump having an impeller defining a plurality of flow channels, the inflow cannula includes a proximal end a distal end proximate the impeller, the distal end including a protuberance extending outward from the inflow cannula.

Abstract: In one example, the disclosure describes a method comprising receiving, by processing circuitry, information indicative of one or more evoked compound action potential (ECAP) signals. The one or more ECAP signals are sensed by at least one electrode carried by a medical lead. The processing circuitry determining that at least one characteristic value of the one or more ECAP signals is outside of an expected range. Responsive to determining that the at least one characteristic value of the one or more ECAP signals is outside of the expected range, the processing circuitry performs a lead integrity test for the medical lead.

Abstract: A flexible printed circuit board (FPCA) of a brain computer interface (BCI) module is configured to interconnect a plurality of emitter assemblies and a plurality of detector assemblies of the BCI module. The FPCA comprises a connector portion for connecting the FPCA to a controller of the BCI module, a plurality of rigid sections, a plurality of flexible sections. A first subset of rigid sections is configured to mount the plurality of emitter assemblies. A second subset of rigid sections is configured to mount the plurality of detector assemblies. Each flexible section is configured to attach the two or more rigid sections of the plurality of rigid sections to each other. The plurality of flexible sections allows the plurality of emitter assemblies and the plurality of detector assemblies to stretch to conform to a head of a user.

Abstract: A light device includes an elongated arm comprising a plurality of light emitting diodes (“LEDs”) disposed at a first end of the elongated arm and configured to be positioned inside an oral cavity and to deliver one of a plurality of types of light treatments to the inside of the oral cavity according to a selected one of a plurality of operating modes. The light device further includes a body coupled to the elongated arm at a second end of the elongated arm. The body includes a battery for providing power to the LEDs. The body further includes a mode module coupled to the battery and the plurality of LEDs and configured to deliver power from the battery to at least one of the plurality of LEDS based on the selected operating mode.

Abstract: Systems for treatment of glaucoma comprise an excimer laser, a plurality of fiber probes, and a processor. Each fiber probe is attachable to the excimer laser to treat a subject having glaucoma by delivering shots from the laser. The processor is configured to monitor and limit a variable number of shots delivered by each fiber probe, the number of shots delivered by each fiber probe programmable within a range. Methods of treating glaucoma include programming a fiber probe to deliver a number of shots from an excimer laser. The fiber probe is inserted into an eye of a subject having glaucoma and adjusted to a position transverse to Schlemm's canal in the eye. A plurality of shots is applied from the excimer laser source while the probe is in the transverse position, thereby treating glaucoma by creating a plurality of perforations in Schlemm's canal and/or the trabecular meshwork.

Abstract: A system for acquiring physiological data from a patient, the system comprising: a smartphone configured for wireless communication; an adapter for releasably mounting to the smartphone; a sensor module for releasably mounting to the adapter, the sensor module comprising at least one sensor for acquiring physiological data from the patient; and a software app running on the smartphone for (i) wirelessly controlling operation of the sensor module and wirelessly receiving the physiological data from the sensor module, and (ii) wirelessly communicating with a remote location.

Abstract: The inventive concept relates to a needle tip for application of current, a hand piece, and a skin treatment apparatus that are equipped with a needle in which an electromagnetically-energized active region is formed as a partial region other than a tip end of the needle is exposed in a non-insulated state.

Abstract: Modulation of the neural activity of a nerve adjacent to the left gastro epiploic artery (LGEA) and/or a nerve adjacent to a short gastric artery (SGA) can modulate the neural activity of the sympathetic nerves that impact splenic function. This is useful for reducing inflammation and providing ways of treating inflammatory disorders.

Abstract: Apnea events may be detected based on a primary biomarker, e.g., respiration, in the one or more physiological signals. The apnea events may be characterized as one of an obstructive sleep apnea (OSA) event, a central sleep apnea (CSA) event, or a combination OSA/CSA event based on a secondary biomarker, e.g., a frequency spectrum or a morphology of the respirations in the one or more physiological signals. A first electrical stimulation may be provided to treat OSA in response to a first one or more of the apnea events being characterized as OSA events. A second electrical stimulation may be provided to treat CSA in response to a second one or more of apnea events being characterized as CSA events. A third electrical stimulation may be provided to treat combination OSA/CSA in response to a third one or more of the apnea events being characterized as combination OSA/CSA events.