Patents Examined by K. Weddington
  • Patent number: 5362753
    Abstract: The present invention relates to a method of feeding female birds with a feed formulation which enhances the hatchability of the eggs laid, as evidenced by an increase in hatching percentage. Poultry diets of this invention include an amount of a carnitine, such as L-carnitine or a L-carnitine salt. The amount present in the diet is such that the hatchability of eggs laid by hens fed this diet is increased.
    Type: Grant
    Filed: April 19, 1993
    Date of Patent: November 8, 1994
    Assignee: Lonza Ltd.
    Inventors: Rene Blum, Josef Leibetseder
  • Patent number: 5356910
    Abstract: There is disclosed a method of alleviating obsessive compulsive disorders which comprises administration of an effective amount of a compound of the formula. ##STR1## where m is 1 or 2;R is H, halogen, loweralkyl, loweralkoxy, arylloweralkoxy, hydroxy, nitro, amino, loweralkylamino or diloweralkylamino;R.sub.1 is H or loweralkyl;R.sub.2 is H or loweralkyl; andR.sub.3 is H, halogen or loweralkyl.
    Type: Grant
    Filed: July 19, 1993
    Date of Patent: October 18, 1994
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Sathapana Kongsamut, Craig P. Smith, Ann T. Woods
  • Patent number: 5354549
    Abstract: The invention relates to metabolically labile water-insoluble esters of formula (I), wherein R.sup.1 is an aliphatic, araliphatic, aryl or heterocyclic group; R.sup.2 is hydrogen or an aliphatic, aryl or araliphatic group; R.sup.3 is as defined for R.sup.1, or R.sup.3 and R.sup.2 together form an alkylene chain; the molecule containing at least one iodine atom and being metabolised to form products which are soluble in body fluids. The esters are used in X-ray and ultrasound image enhancement.
    Type: Grant
    Filed: December 5, 1991
    Date of Patent: October 11, 1994
    Assignee: Nycomed Imaging AS
    Inventors: Jo Klaveness, Per Strande
  • Patent number: 5352707
    Abstract: A method for treating airway congestion which comprises administering an effective amount of the compound of formula II which follows ##STR1## or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: March 26, 1992
    Date of Patent: October 4, 1994
    Assignee: Harbor Branch Oceanographic Institution, Inc.
    Inventors: Shirley A. Pompni, Vincent P. Gullo, Ann C. Horan, Mahesh G. Patel, Stephen Coval
  • Patent number: 5348956
    Abstract: New substituted cyclopropylamino-1,3,5-triazines having the formula ##STR1## wherein R.sub.1 is C.sub.1 -C.sub.3 -alkyl, C.sub.3 -C.sub.5 -cycloalkyl or C.sub.1 -C.sub.3 -alkyl-C.sub.3 -C.sub.5 -cycloalkylR.sub.2 is bis(2-hydroxyethyl)amino, 3-hydroxy-1-azetidinyl, 3-methoxy-1-azetidinyl, 3-oxo-1-azetidinyl, morpholino, 4-hydroxypiperidino, thiomorpholino, thiomorpholino S-oxide, thiomorpholino S,S-dioxide, 3-thiazolidinyl, 3-thiazolidinyl S-oxide, 3-thiazolidinyl S,S-dioxide or 8-oxa-3-azabicyclo[3,2,1]oct-3-yl. Processes for the preparation thereof and pharmaceutical composition containing them are also given. The compounds are useful for the treatment of inflammation and asthma.
    Type: Grant
    Filed: August 9, 1993
    Date of Patent: September 20, 1994
    Assignee: UCB S.A.
    Inventors: Berend J. Van Keulen, Solo Goldstein, Eric Cossement, Jean Gobert, Ernst Wulfert
  • Patent number: 5344652
    Abstract: A stable, shippable microbicide solution, having improved anticorrosive properties comprising a two part system, the first part consists of a mixture of acetic acid, hydrogen peroxide, peracetic acid, and water. This is referred to for brevity as a peroxide/peracid solution. The second consists of water having dissolved therein a wetting agent which is preferably Victawet.RTM. 35B which is the sodium hydroxide reaction product of an aliphatic alcohol and phosphorous pentoxide. Three other Victawet.RTM. agents have proven operative. Alternatively, Fluorad.TM. FC95, which is a agent of potassium perfluoroalkyl sulfonates may be used. The microbicide may also be a premixed one component system containing the anticorrosive agents of the invention.
    Type: Grant
    Filed: December 10, 1991
    Date of Patent: September 6, 1994
    Assignee: Minntech Corporation
    Inventors: Robert T. Hall, II, Jo-Ann B. Maltais, Louis C. Cosentino
  • Patent number: 5344832
    Abstract: A process for the long term modification and regulation of lipid and glucose metabolism--generally to reduce obesity, insulin resistance, and hyperinsulinemia or hyperglycemia, or both (these being the hallmarks of noninsulin dependent, or Type II diabetes)--by administration to a vertebrate, animal or human, of a dopamine agonist and a prolactin stimulator. The dopamine agonist and prolactin stimulator are administered in daily dosages, respectively, at a time of day dependent on the normal circadian rhythm of fat and lean members of a similar species. Decreases in body fat deposits result by treatment of an obese species on a daily timed sequence based on circadian rhythms of the peak prolactin, or peak prolactin and peak glucocorticosteroid, blood level established for lean insulin sensitive members of a similar species.
    Type: Grant
    Filed: June 24, 1991
    Date of Patent: September 6, 1994
    Assignees: The Board of Supervisors of Louisiana University and Agricultural and Mechanical College, Ergo Science Incorporated
    Inventors: Anthony H. Cincotta, Albert H. Meier
  • Patent number: 5342853
    Abstract: The use of nor-verapamil and nor-gallopamil and the salts thereof with physiologically tolerated acids is disclosed for the preparation of drugs with antiarteriosclerotic properties.
    Type: Grant
    Filed: November 12, 1991
    Date of Patent: August 30, 1994
    Assignee: Knoll AG
    Inventors: Claus D. Mueller, Liliane Unger
  • Patent number: 5340838
    Abstract: The present invention provides a method of inhibiting gastric acid secretion in mammals by administering a 5-HT1A agonist compound or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: May 26, 1993
    Date of Patent: August 23, 1994
    Assignee: Eli Lilly and Company
    Inventors: Jaswant S. Gidda, John M. Schaus
  • Patent number: 5340577
    Abstract: A defined probiotic or composition of anaerobic bacteria effective for controlling or inhibiting Salmonella colonization of fowl. The probiotic includes populations or cultures of substantially biologically pure bacteria, which bacteria include:(a) at least one Lactobacillus species;(b) one or both of:Lactococcus lactis, andCitrobacter freundii; and(c) at least one of:one or more Enterococcus species,one or more Bifidobacterium species,one or more Propionibacterium species, andone or more Escherichia species.In use, the probiotic is administered to the subject fowl in an amount effective for inhibiting Salmonella colonization thereof.The invention also relates to a novel method for isolating probiotics which are effective for controlling or inhibiting Salmonella colonization of fowl, from fecal droppings or cecal contents of adult fowl. The droppings or cecal contents are combined with a culture medium and incubated without dilution (i.e. batch culture) under anaerobic conditions.
    Type: Grant
    Filed: July 29, 1992
    Date of Patent: August 23, 1994
    Assignee: The United States of America, as represented by the Secretary of Agriculture
    Inventors: David J. Nisbet, Donald E. Corrier, John R. DeLoach
  • Patent number: 5340834
    Abstract: A method for increasing muscle mass and decreasing fat in chickens which includes administering orally to a chicken, a biologically effective amount of chromium citrate.
    Type: Grant
    Filed: January 5, 1993
    Date of Patent: August 23, 1994
    Inventor: Paul A. Stitt
  • Patent number: 5338461
    Abstract: Disclosed is a method of disinfecting a water system with a blue pigmented dry oxidizer composition consisting of: (a) from 99.5-99.99% by weight of one of the following compositions:(i) 1,3 dichloro-5,5-dimethylhydantoin;(ii) a mixture of the 1-Bromo-3-chloro 5,5-dimethylhydantoin and 1,3-dichloro 5,5-dimethylhydantoin and 1,3-dichloro-5, ethyl-5-methylhydantoin;(iii) trichloro-s-triazinetrione;(iv) sodium dichloro-s-triazinetrione;(v) a mixture of trichloro-s-triazinetrione and sodium bromide;(vi) a mixture of sodium dichloro-s-triazinetrione and sodium bromide;(vii) 1-bromo-3-chloro-5,5-dimethylhydantoin;(viii) a mixture of 1,3-dichloro-5,5-dimethylhydantoin and potassium bromide;(ix) calcium hypochlorite(x) lithium hypochlorite(b) and from 0.01-0.5% by weight of lazurite.
    Type: Grant
    Filed: September 24, 1992
    Date of Patent: August 16, 1994
    Assignee: Bio-Lab, Inc.
    Inventor: Ronald L. Jones
  • Patent number: 5338762
    Abstract: A clear, efficacious, aqueous microemulsion of an agriculturally active carbamate ester insecticide.
    Type: Grant
    Filed: November 19, 1992
    Date of Patent: August 16, 1994
    Assignee: ISP Investments Inc.
    Inventor: Kolazi S. Narayanan
  • Patent number: 5336672
    Abstract: Egg production in poultry can be increased by the administration of chromium picolinate, preferably as a feed additive. The amounts of chromium picolinate required are low, so this method of increasing egg production can be administered both easily and economically.
    Type: Grant
    Filed: July 21, 1992
    Date of Patent: August 9, 1994
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Lincoln L. Southern, Jr., Timothy G. Page
  • Patent number: 5336486
    Abstract: A method for suppressing appetite comprising administering by mouth to a subject an amount of polycarbophil that is effective to suppress the appetite of the subject without inducing a laxative effect in said subject.
    Type: Grant
    Filed: March 28, 1991
    Date of Patent: August 9, 1994
    Assignee: TheraTech, Inc.
    Inventor: Ramesh N. Acharya
  • Patent number: 5336692
    Abstract: High molecular weight petroleum fractions which have a low white oil content are admixed with a volatile siloxane, hexamethyldisiloxane, octamethylcyclotetrasiloxane and/or decamethylcyclopentasiloxane and a compound that is both hydrophobic and hydrophilic to provide an ointment base which enables these petrolatum fractions to be spread easily on the skin. Evaporation of the solvent leaves a high molecular weight petrolatum film on the skin that is nonirritating and yet highly resistant to mechanical removal.
    Type: Grant
    Filed: June 18, 1991
    Date of Patent: August 9, 1994
    Assignee: Medicis Pharmaceutical Corporation
    Inventors: Eugene H. Gans, Hans R. Suess
  • Patent number: 5334592
    Abstract: Methods and compositions are disclosed employing combinations of antihistamines with certain diaryl tetrahydrofuran, diaryl tetrahydrothiophene, triazolobenzodiazepine or thienotriazolodiazepine PAF-antagonist compounds in the treatment of allergic reactions.
    Type: Grant
    Filed: October 13, 1992
    Date of Patent: August 2, 1994
    Assignee: Schering Corporation
    Inventor: M. Motasim Billah
  • Patent number: 5331003
    Abstract: The present invention is directed to anticoccidial methods, animal feed premixes, and animal feeds, employing a specified o-phenylenediamine or benzimidazole. The present invention is also directed to anticoccidial methods, animal feed premixes, and animal feeds employing two active agents. In such combined therapy, a first substance is a polyether antibiotic, and the second substance is a designated o-phenylenediamine, benzimidazole, or benzimidazoline.
    Type: Grant
    Filed: March 26, 1993
    Date of Patent: July 19, 1994
    Assignee: Eli Lilly and Company
    Inventor: George O. P. O'Doherty
  • Patent number: 5326789
    Abstract: Clear, stable, efficacious, aqueous microemulsions of an active triazole fungicide, e.g. penconazole, optionally with another agriculturally active chemical, are provided herein. The aqueous microemulsions are obtained by providing an inert matrix composition comprising a defined mixture of nonionic surfactants, including a C.sub.6 -C.sub.18 alkylpyrrolidone, e.g. octylpyrrolidone, an alkylphenol ethoxylated alcohol having an HLB.gtoreq.6, preferably 10-20, e.g. nonylphenol ethoxylated alcohol with 9 EOs, and an anionic surfactant selected from a salt of dodecyl sulfate, dodecylbenzene sulfonate, dodecyltoluene sulfonate and lignin sulfonate, preferably sodium dodecyl sulfate, and water, optionally with a C.sub.1 -C.sub.4 alkylpyrrolidone, e.g. N-methylpyrrolidone, and water. The inert matrix composition is admixed with a triazole fungicide, present in a C.sub.1 -C.sub.4 alkylpyrrolidone, if not already present in the inert matrix composition, to form a microemulsion concentrate.
    Type: Grant
    Filed: October 22, 1992
    Date of Patent: July 5, 1994
    Assignee: ISP Investments Inc.
    Inventor: Kolazi S. Narayanan
  • Patent number: 5324719
    Abstract: A therapeutical method for treating hypertension is disclosed which comprises administering to a patient in need thereof an effective amount of an imino derivative of 3.beta., 14.beta.-dihydroxyetianaldehyde, particularly 17.beta.-guanidinoiminomethyl-5.beta.-androstan-3.beta.,14.beta.-diol.
    Type: Grant
    Filed: June 22, 1993
    Date of Patent: June 28, 1994
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
    Inventors: Marco Frigerio, Nicoletta Almirante, Alberto Cerri, Tiziana Cova, Mara Ferrandi, Patrizia Ferrari