Abstract: Emulsions prepared using a silicone polyether as the surfactant are stable in an aqueous media in the presence of salts such as electrolytes, alcohols, solvents, and combinations thereof. The emulsions can be prepared by (i) polymerizing an unsaturated monomeric organic compound in water containing the monomer, a silicone polyether, a catalyst, and optional organic surfactants, until a polymer of desired molecular weight is obtained; (ii) by mechanically emulsifying a non-silicon atom containing organic oil in water using a silicone polyether with or without addition of other organic surfactants; and (iii) by mixing and adding a silicone polyether to a previously prepared emulsion.

Abstract: A skin barrier lotion for protection against contact with irritants comprises: about 5 to 15 percent by weight of a long-chain fatty acid; about 1 to 5 percent by weight of a long-chain fatty alcohol; about 1 to 10 percent by weight of a hydrocarbon oil; about 1 to 30 percent by weight of a silicone skin protectant; about 0.5 to about 5 percent by weight of an alkanolamine; about 0.5 to about 5 percent by weight of a humectant; about 0.5 to about 10 percent by weight of an inorganic skin protectant; about 0.5 to 15 weight percent of a preservative; and about 50 to 90 percent by weight water. Optionally, the lotion will also contain up to about 5 percent by weight of a fragrance, odor neutralizer or a mixture thereof.

Abstract: A pigmented anhydrous cosmetic composition for reducing the shiny appearance of skin and cosmetically improving the appearance of skin imperfections comprising a cosmetically effective amount of mushroom extract and a method for reducing the shiny appearance of skin and cosmetically improving the appearance of skin imperfections comprising applying to the skin an anhydrous cosmetic composition containing mushroom extract.

Abstract: The present invention relates in general terms to the use of saponins or sapogenols, particularly those extracted from a plant, preferably from soya or Medicago, in cosmetology and for the manufacture of pharmaceutical compositions for treating the skin in order to increase the amount of collagen IV in the dermo-epidermal junction. It further relates to novel cosmetic or pharmaceutical compositions which promote an increase in the amount of collagen IV in the dermo-epidermal junction, and to a method of cosmetic treatment using a saponin or a sapogenol. The invention is applicable in cosmetics, preferably in an anti-wrinkle treatment, and in pharmacy in the treatment of diseases associated with a deficiency of the dermo-epidermal junction resulting from an insufficient amount of collagen IV.

Abstract: The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vivo in aqueous media. Specifically, a dye is combined with a conjugated nitrogen-containing heterocyclic aromatic boronic acid-substituted bis-onium compound in the presence of a sugar, such as fructose or glucose. The viologens are preferred as the aromatic conjugated nitrogen-containing boronic acid substituted compounds. The method is useful to determine sugar levels in a human being.

Abstract: The invention concerns the use of peptides of general sequence X-Thr-Thr-Lys-Y, wherein in particular X=lysine and Y=serine, in cosmetic or dermopharmaceutical compositions. It is moreover advantageous to use said peptides in mutual combination. In order to enhance their activity and their stability, the peptides are chemically modified to increase their lipophilicity, by grafting on the N-terminal amine of X, either a fatty acid chain, or by esterification or amidation of the C-terminal carboxyl group of Y. The peptides can be obtained by synthesis, biotechnology or controlled hydrolysis or plant proteins. The resulting compositions are advantageously used for stimulating healing, hydrating or all skin treatments. They are particularly active against formation or deterioration of wrinkles and against all the consequences of skin ageing, whether natural or induced (heliodermia, pollution), as well as for dry skin.

Abstract: An antiseptic/antifungal agent comprising 2,2-dialkyl-1,3-propanediol represented by the formula (I): wherein R1 and R2 can either be identical or different from each other, and both denote an alkyl group with a carbon number of 1-4, and an endermic liniment containing the same. In addition, an endermic liniment containing 3-methyl-3-methoxybutanol and 1,2-pentanediol, and an endermic liniment containing 3-methyl-3-methoxybutanol and 2-phenoxyethanol, is provided.

Abstract: Spontaneously formed highly stable clear water-in-oil microemulsions containing only small amounts of water can be prepared by combining and simply hand shaking (i) 0.1 to 9 percent by weight of water; (ii) greater than 80 percent by weight of a volatile cyclic alkyl siloxane or volatile linear alkyl siloxane; and (iii) 3 to 10 percent by weight of certain silicone polyether surfactants. The microemulsions are useful in personal care applications.

Abstract: Sensitive human skin/scalp/mucous membrane conditions, for example skin irritation and/or dry patches and/or erythemas and/or dysaethetic sensations and/or sensations of heating and/or pruritus, are therapeutically treated by topically applying thereto an effective condition-alleviating amount of at least one inhibitor of at least one excitatory amino acid.

Abstract: The present invention relates to highly radioactive, miniaturized, cylindrical strontium 90 titanate, strontium 90 zirconate, and strontium 90 silicate radiation sources having an activity exceeding 25 mCi/mm3, preferably ≧30 mCi/mm3, and a diameter less than 0.7 mm, preferably less than 0.4 mm. Another subject of this invention is a method for the production of these extremely small, but highly radioactive radiation sources.

Abstract: A therapeutic composition of lorazepam and its pharmaceutically acceptable derivatives are provided for intranasal administration of at least one predetermined volumetric unit dose in the form of a spray by means that delivers one or more therapeutically prescribed unit doses that are highly accurate as to the volume discharged and which leave no significant quantity of the composition in the delivery means.

Abstract: A composition in the form of a water-in-oil emulsion containing fibers, at least one silicone surfactant and at least one clay. The composition may be used, for example, for caring for, treating, making up or cleansing the skin, the lips, the eyelashes and/or the hair.

Abstract: The ability to incorporate iodoform, tetracycline and a combination of iodoform/tetracycline into root canal gutta percha points is described. The iodoform, tetracycline and iodoform/tetracycline combination are bound within the gutta percha points. They act as a reservoir of antimicrobial that is capable of diffusing onto the surface of the gutta percha thereby inhibiting the colonization of bacteria on the gutta percha points and within the root canal system. Tetracycline is capable of coalescing within the dentinal tubules to inhibit long term microbial growth. These medicated gutta percha points are site specific, surface acting antimicrobial gutta percha points. A method of the usage and delivery of amorphous form iodoform gutta percha, iodoform/tetracycline gutta percha, or tetracycline gutta percha within a heated compule with a pressure plunger by delivering the thermo-softened heat labile amorphous form via a pressure extrusion system through a cannula into the prepared root canal system.

Abstract: The present invention is directed to a complex comprising a redox-active metal cluster in a chemically inert shell. The inventive complex has the formula M8(&mgr;4-E)4(&mgr;-L)12X, where M is chosen from a transition metal, a lanthanide, an actinide and mixtures thereof; E is a chalcogenide; L is a bridging ligand; and X is a terminal ligand. The chemically inert shell enables the complex to exhibit structural stability over several oxidation states, and to exhibit reversible electrochemical reduction properties. A single reactor method of making this complex from simple starting materials is also disclosed. The active center further allows the octanuclear complex to be used in making supercluster assemblies that have electron transfer properties or in making contrasting agents for MRI applications, for example.

Abstract: A weak acid skin cleanser containing an alkali salt of N-acylamino acid and maltitolhydroxy aliphatic ether, or a hydroxy ether carboxylic acid-based anionic surfactant, or polyethylene powder, as well as water and an organic acid. Also, a weak acid skin cleanser containing an alkali salt of N-acylamino acid, a betaine-based ampholytic surfactant, water, and an organic acid. The weak acid skin cleansers mentioned above provide creamy and rich foaming, rapid rinsing, refreshing sensation during use, moist skin sensation after cleaning, and shelf stability of the base agent (separation, offensive odor, discoloration, etc.), and are free of increasing hardness over time at room temperature and below.

Abstract: Novel methods of non-invasive intravascular surgery are disclosed, which include the intravascular administration of a composition comprising gas or gaseous precursor filled vesicles, followed by application of ultrasound in an amount sufficient to induce activation or rupture of the vesicles. The methods optionally also include the step of scanning the patient with diagnostic imaging to determine the presence of the vesicles in the region.

Abstract: A silicone compound useful in cosmetic materials and skin cleansing compositions which have no oily feel although they spread easily and smoothly, give moist, fresh and dry feelings to the users, have durable effects, and are highly stable to temperature changes and long-term storage. They additionally also absorb makeup cosmetics and sebum stains well when used in a skin-cleansing composition.

Abstract: A sensitizer for tumor treatment has a structure such that a lipophilic group and a hydrophilic group are bound to one and the same carbon atom in a compound containing a xanthene dye structure. It is important that the lipophilic group and hydrophilic group are bound to one and the same carbon atom; if they are separated from each other, no sufficient effect is obtained. Thus, the sensitizer possesses both lipophilicity and hydrophilicity. This sensitizer has a function of promoting acoustic cavitation and a function of revealing an antitumor effect and is an agent highly accumulable in tumor tissues. Thus, this sensitizer is highly selective for tumor tissues and enables the treatment of malignant tumor using ultrasound.

Abstract: The present provides a composition that includes, in a physiologically acceptable medium: an aqueous phase dispersed in an oily phase with a silicone emulsifier; wherein the aqueous phase represents at least 80% by weight relative to the total weight of the composition; wherein the silicone emulsifier is an alkyldimethicone copolyol comprising an HLB of less than 8; and wherein a weight ratio of the oily phase to the silicone emulsifier is greater than or equal to 5. The present invention also provides a cosmetic, which includes the above-mentioned composition and methods of using the above-mentioned composition for treating, protecting, caring for, or removing make-up from the skin, lips or hair, cleansing the skin, lips or hair, and making up the skin or lips, treating, protecting, and caring for the scalp, and treating greasy skin. The composition can be used in particular in cosmetics and/or dermatology.

Abstract: A composite powder prepared by coating a ramentaceous substrate with at least two color layers. A difference between the maximum value and the minimum value of the ab hue angle hab (hmax−hmin) as defined in the recommendation on uniform color space by CIE is in the range from 10° to 180°. A ratio of the maximum value vs the minimum value of the brightness L* as defined in the recommendation is in the range from 1.0 to 2.0. According to the viewing angle, the color tone of the composite powder changes.