Patents Examined by Leslie R. Deak
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Patent number: 11963932Abstract: In certain embodiments, a vial adaptor for removing liquid contents from a vial comprises a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial comprises a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial. In order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.Type: GrantFiled: November 25, 2019Date of Patent: April 23, 2024Assignee: ICU Medical, Inc.Inventors: John M. Seifert, Thomas F. Fangrow
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Patent number: 11938058Abstract: An illustrative method for reducing intraocular pressure in a patient may comprise deploying an ocular implant adapted to reside at least partially in a portion of Schlemm's canal of an eye and administering a therapeutic agent comprising a Rho kinase (ROCK) inhibitor to the patient. The ocular implant may be configured to lower the intraocular pressure from an initial to a second pressure within a first range and the therapeutic agent may lower an intraocular pressure to a third pressure within a second range, the third pressure lower than the second pressure.Type: GrantFiled: December 15, 2016Date of Patent: March 26, 2024Assignee: Alcon Inc.Inventors: Andrew T. Schieber, Charles L. Euteneuer, David T. Van Meter, Kenneth M. Galt
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Patent number: 11938253Abstract: Provided herein is a gas exchange composite membrane and methods of making the same. The gas exchange composite membrane may find use in a method of exchanging gas with blood in a subject in need of blood oxygenation support, which method is also disclosed. Also provided herein are systems and kits that find use in performing the methods of exchanging gas with blood.Type: GrantFiled: May 7, 2020Date of Patent: March 26, 2024Assignee: The Regents of the University of CaliforniaInventors: Shuvo Roy, Torin Yeager, Emily Abada, Ajay S. Dharia
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Patent number: 11931501Abstract: A dialysis sheath is used with a catheter that cleans clots from a synthetic blood vessel or fistula. The dialysis sheath comprises a main hollow body and a stop mechanism. The main body has a lower portion for insertion into the synthetic blood vessel or fistula. The stop mechanism is movable between (i) a first position in which the stop mechanism is adjacent to or within a surface of the main hollow body and (ii) a second position in which the stop mechanism radially protrudes from the main hollow body. The stop mechanism is configured to engage an inner surface of the synthetic blood vessel or fistula to maintain the lower portion of the dialysis sheath within the synthetic blood vessel or fistula when the dialysis sheath is moved to a different position. The stop mechanism can be fluid-actuated and include a balloon-like structure.Type: GrantFiled: June 27, 2023Date of Patent: March 19, 2024Inventor: Evan T. Neville
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Patent number: 11925580Abstract: A system for preparation of an implant and ab interno insertion of the implant into an eye including a handle having one or more actuators and an elongated shaft having an outer sheath and an elongate member positioned within a lumen of the tubular outer sheath. The system includes a recess sized for holding a patch of material fixed relative to the handle and a cutting member movable relative to the handle and to the recess. The cutting member cuts the patch of material into an implant as the cutting member moves towards a cutting configuration. The implant, once cut, is axially aligned with the lumen of the tubular outer sheath. The inner elongate member is movable relative to the tubular outer sheath to advance the implant into a deployment position in the lumen of the tubular outer sheath for delivery into the eye. Related devices and methods are provided.Type: GrantFiled: January 30, 2020Date of Patent: March 12, 2024Assignee: Iantrek, Inc.Inventor: Tsontcho Ianchulev
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Patent number: 11918758Abstract: A catheter assembly for use in accessing a vasculature of a patient is disclosed. In one embodiment, the catheter assembly includes a catheter body that includes a flattened oval outer surface and defines first and second lumens. The catheter body defines a distal tip region that includes a venous lateral opening that is in fluid communication with the first lumen and includes a distal-facing portion. The distal tip region further includes an arterial lateral opening that is in fluid communication with the second lumen, includes a distal-facing portion, and is substantially un-staggered with respect to the venous lateral opening. A distal end opening is in fluid communication with a power injectable third lumen. In another embodiment, the first and second lumens each generally include a reniform cross-sectional shape. In yet another embodiment, a dual-lumen catheter includes first and second lumens that each define a modified ellipse cross-sectional shape.Type: GrantFiled: December 23, 2019Date of Patent: March 5, 2024Assignee: C. R. Bard, Inc.Inventors: Kelli D. Oborn, Ryan T. Moehle, William R. Barron
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Patent number: 11918542Abstract: A liquid transfer device is described. The device comprises a connector body comprising a projection portion defining a tab and an IV port arranged at a first end of the connector body, the IV port comprising an elongate connecting member projecting therefrom and defining a cutout. The projection portion is configured to be received by the elongate connecting member, and the tab is configured to mate with the cutout so as to rotationally fix the IV port relative to the connector body.Type: GrantFiled: January 31, 2020Date of Patent: March 5, 2024Assignee: West Pharma. Services IL, Ltd.Inventors: Aviad Yedgar, Amir Lev, Uri David
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Patent number: 11911543Abstract: An autotransfusion system for separating fluid constituents includes a centrifuge housing and a rotatable driving member mounted within the centrifuge housing. The rotatable driving member is configured to receive therein and rotationally engage any one of a plurality of centrifuge bowls with different heights. In some embodiments, the centrifuge bowl is integrated with a fluid line organizer to provide for easy and efficient organization of a plurality of different fluid lines incorporated into the autotransfusion system. In some embodiments, the centrifuge bowl and fluid line organizer are easily and efficiently coupled to the centrifuge housing for autotransfusion processing. After autotransfusion processing, the centrifuge bowl and fluid line organizer are easily and efficiently decoupled from the centrifuge housing and discarded.Type: GrantFiled: March 12, 2020Date of Patent: February 27, 2024Assignee: Sorin Group Italia S.r.l.Inventors: Andrea Galavotti, Elisa Maculan, Giampaolo Simonini, Ivo Panzani
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Patent number: 11903902Abstract: Fluid transfer couplings or connectors including dual function press-in bottle adaptors supporting different syringe types, connectors having a universal port for supporting different syringe types, transfer couplings compatible for use with different syringe types. Other caps and closures incorporating couplings for fluid transfer with different syringe types is also disclosed.Type: GrantFiled: December 31, 2022Date of Patent: February 20, 2024Inventor: Benjamin Martin Davis
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Patent number: 11896789Abstract: A device and system for flushing a shunt catheter utilizes the available cerebrospinal fluid (CSF) to flush a blocked catheter. The CSF is pressurized to a predetermined amount and then allowed to suddenly, rapidly and forcefully purge any occlusions. The rapid release of CSF produces flow jets from the catheter pores into the ventricle. This impulse, or “cough”, will push and divert choroid plexus and/or other blockages away from the pores. The device and system may then be allowed to refill at a slow rate, thus reducing the possibility of rapid suction of fluid back into the system and the attendant possibility of drawing the choroid plexus back into the pores. The catheter at the proximal end may also include back-up pores that can be opened to restart flow from the ventricle should the primary pores remain blocked after a flushing attempt.Type: GrantFiled: October 16, 2019Date of Patent: February 13, 2024Assignee: Children's Medical Center CorporationInventors: Joseph Madsen, Tomer Anor
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Patent number: 11896246Abstract: A system for removing an undesirable material from within a vessel is provided. The system includes a cannula designed for maneuvering within a blood vessel to a site of interest and applying a suction force, such that the undesirable material can be captured and removed along the cannula away from the site. The system also may include a catheter having a balloon at its distal end. The balloon may be designed to be positioned adjacent to the undesirable material such that the undesirable material is situated between the balloon and the cannula. The catheter may also be designed to subsequently impart a force onto the undesirable material for removal of the undesirable material. A method for removing an undesirable material from within a vessel is also provided.Type: GrantFiled: October 29, 2019Date of Patent: February 13, 2024Assignee: AngioDynamics, Inc.Inventors: Lishan Aklog, Michael Glennon
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Patent number: 11872333Abstract: An apparatus for locating and venting pathogen cells in blood. A cassette has a plurality of thin holding chambers that are filled with blood drawn from a patient. A light source illuminates each of the holding chambers and passes light to an underlying sensor array such that the cells in the blood produce shadow images of the cells in the sensor array. A processor performs pattern recognition to identify and locate the pathogen cells by use of an image library. After the pathogen cells are located, a pump is operated to move the identified cells to a processing zone. When each identified cell reaches the processing zone, a control voltage is generated to open a valve to vent the identified pathogen cells. The pump refills the cassette holding chambers, returns the processed blood to the patient, and the procedure is repeated for a treatment time period.Type: GrantFiled: July 25, 2022Date of Patent: January 16, 2024Inventors: William M. Gosney, Dale B. Nixon
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Patent number: 11865041Abstract: Devices, methods and kits are described for reducing intraocular pressure. The devices include a support that is implantable within Schlemm's canal and maintains the patency of the canal without substantially interfering with transmural fluid flow across the canal. The devices utilize the natural drainage process of the eye and can be implanted with minimal trauma to the eye. Kits include a support and an introducer for implanting the support within Schlemm's canal. Methods include implanting a support within Schlemm's canal, wherein the support is capable of maintaining the patency of the canal without substantial interference with transmural fluid flow across the canal.Type: GrantFiled: July 30, 2019Date of Patent: January 9, 2024Assignee: SIGHT SCIENCES, INC.Inventors: David Y. Badawi, Paul Badawi
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Patent number: 11839526Abstract: A blood flow regulator for creating a shunt in the heart, comprising; a proximal element having a general disc-shape, defined by a braid of one or more wires extending about a central aperture of the proximal element; a distal element having a general disc-shape, defined by a braid of one or more wires extending about a central aperture of the distal element; and a third element defining a neck section intermediate the proximal and distal elements and forming a cavity having a diameter no greater than a diameter of each of the distal and proximal elements, wherein said distal element comprises at least one loop of a wire extending radially outwardly from a center of the distal element and returning towards said center of said distal element.Type: GrantFiled: February 28, 2020Date of Patent: December 12, 2023Assignee: Occlutech GmbHInventors: Joseph John Vettukattil, Mehmet Hakan Akpinar
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Patent number: 11826504Abstract: A catheter system can include a tubular body, and at least one of a targeting system coupled to the tubular body, an expandable member, or a fluid injection port. A method of identifying a bifurcation can include inserting a catheter system into a first vessel, positioning the catheter system at a first location, expanding an expandable member to occlude the first vessel, delivering contrast material so the contrast material pooling proximate to the expandable member, and reviewing a shape of the contrast material in the first vessel under fluoroscopy.Type: GrantFiled: January 21, 2020Date of Patent: November 28, 2023Assignee: LimFlow GmbHInventors: Timothy Lenihan, Steven Kum, Marcus Wenzel, Sophie Humbert, David Hugo Deaton
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Patent number: 11801336Abstract: An operational unit for locating and neutralizing pathogen cells in blood includes a time use cassette which has a plurality of thin holding chambers that are filled with blood drawn from a patient. A light source illuminates each of the holding chambers and passes light to an underlying sensor array such that the cells in the blood selectively block the light to produce shadow images of the cells in the sensor array. A processor performs pattern recognition to identify and locate the pathogen cells by use of an image library. After the pathogen cells are located, an electric field is activated in the cassette chamber areas that include the identified pathogen cells. Sufficient electric field energy is applied to destroy the identified pathogen cells. A pump refills the cassette holding chambers, returns the neutralized-pathogen blood to the patient, and the process is repeated for a period of time.Type: GrantFiled: July 25, 2022Date of Patent: October 31, 2023Inventors: William M. Gosney, Dale B. Nixon
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Patent number: 11793719Abstract: The present invention relates to a method for enabling hospitals or clinics to administer a dose of a drug to patients in need thereof while avoiding steps of manipulation, dilution, reconstitution, dispensing, sterilization, transfer, handling or compounding before intravenous administration. The present invention further relates to a perfusion system comprising different sets of perfusion containers, each container comprising a ready-to-infuse, stable, sterile, aqueous perfusion solution of a drug, wherein the set of perfusion containers alone or in combination provides for direct intravenous administration of a desired dose of the drug to a patient in need thereof, such that the delivered dose is equal to or within ±5% of the calculated dose.Type: GrantFiled: September 20, 2022Date of Patent: October 24, 2023Assignee: SUN PHARMACEUTICAL INDUSTRIES LIMITEDInventors: Samarth Kumar, Prashant Kane, Subhas Balaram Bhowmick, Kirti Ganorkar, Nishit Patel, Ashish Anilrao Dubewar, Umeshkumar Mukeshbhai Patel
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Patent number: 11786710Abstract: The present invention provides a skull implant-type automatic fluid drain device comprising: a body having a first port to be connected to a catheter, a second port provided opposite the first port, and a flow passage connecting the first port and the second port; a separation member for separating the flow passage into first and second sub-channels; a first valve fixed to the separation member and provided to allow the movement of a fluid that moves from the first port to the second port in the first sub-channel; and a second valve fixed to the separation member and provided to allow the movement of a fluid that moves from the second port to the first port in the second sub-channel, wherein each of the first valve and the second valve has an inflow end portion that is open and a discharge end portion provided in a closed state such that the same is selectively opened at an allowed opening pressure or higher; each of the first valve and the second valve is configured such that the inner flow sectional area deType: GrantFiled: April 24, 2018Date of Patent: October 17, 2023Assignees: National Cancer Center, Eulji University Industry Academy Cooperation FoundationInventors: Heon Yoo, Kwang Gi Kim, Young Tae Kim, Seung Hoon Lee
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Patent number: 11766355Abstract: The present technology relates to adjustable shunting systems and methods. In some embodiments, the present technology includes an adjustable shunting system that includes a drainage element having an inflow portion configured for placement within a patient. The system can also include a flow control assembly having a gating element operably coupled to the outflow portion of the drainage element. The flow control assembly can further include a first actuation element and a second actuation element coupled to the gating element. The first and second actuation elements can be configured to selectively move the gating element relative to the outflow portion to control an amount of fluid flow therethrough. The first and second actuation elements can each extend less than entirely around a perimeter of the drainage element.Type: GrantFiled: March 19, 2021Date of Patent: September 26, 2023Assignee: Shifamed Holdings, LLCInventors: Claudio Argento, Richard Lilly, Robert Chang, Katherine Sapozhnikov, Tom Saul
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Patent number: 11752251Abstract: Improved systems and methods for extracorporeal blood temperature control and patient temperature control, e.g., for induced hypothermia and optional normothermia, may include or otherwise employ a heat exchanger for cooling/warming of a fluid, a thermal exchange module having fluidly-isolated first and second volumes, and a fluid pump for circulating the fluid through the heat exchanger and the first volume of the thermal exchange module. A blood pump may be provided for the flow of blood through the second volume of the thermal exchange module, and a first controller may be provided for providing output signals for use in operation of the heat exchanger to selectively control thermal exchange between the fluid circulated through the first volume of the thermal exchange module and the blood flowed through the second volume of the thermal exchange module, thereby providing for selective cooling/warming of the blood.Type: GrantFiled: October 9, 2019Date of Patent: September 12, 2023Assignee: Medivance IncorporatedInventors: Marc E. Voorhees, Christopher Park, Salvatore Privitera