Patents Examined by Leslie R. Deak
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Patent number: 11529258Abstract: The present technology is directed to adjustable shunts for treating glaucoma. In particular, some embodiments provide shunts having a plurality of individually actuatable flow control elements that can control the flow of fluid through associated ports and/or flow lumens. For example, each individually actuatable flow control element can be actuated to block and/or unblock a corresponding port and/or flow lumen. Accordingly, the shunts described herein can be manipulated into a variety of configurations that provide different drainage rates based on whether the ports and/or flow lumens are blocked or unblocked, therefore providing a titratable glaucoma therapy for draining aqueous from the anterior chamber of the eye.Type: GrantFiled: January 22, 2021Date of Patent: December 20, 2022Assignee: Shifamed Holdings, LLCInventors: Robert Chang, Katherine Sapozhnikov, Claudio Argento, Tom Saul, Richard Lilly
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Patent number: 11517477Abstract: The present technology is directed to adjustable flow glaucoma shunts and methods for making and using such devices. In many of the embodiments described herein, the shunts include a generally flat frame. The frame can include an elongated portion having a lumen extending therethrough and a bladder portion defining an interior chamber that is in fluid communication with the lumen. When implanted in a patient's eye, aqueous can drain from the anterior chamber to a target outflow location via the lumen and interior chamber. In some embodiments, the shunts include a flow control assembly positioned within the interior chamber of the bladder portion to control the flow of aqueous through the lumen.Type: GrantFiled: October 9, 2020Date of Patent: December 6, 2022Assignee: Shifamed Holdings, LLCInventors: Richard Lilly, Claudio Argento, Katherine Sapozhnikov, Christopher J. Engelman, Jean Orth
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Patent number: 11511028Abstract: A system for reducing toxicity from intravascular triggered drug delivery includes a chamber comprising an inflow port, an outflow port, and a filter positioned upstream of the outflow port. A trigger module is configured to trigger the release of a drug from an intravascular triggered drug delivery system present in blood in the chamber. A method for reducing toxicity from intravascular triggered drug delivery includes the steps of removing blood comprising an intravascular triggered drug delivery system from a patient's vascular system and delivering the blood to a chamber, applying a trigger to the blood to release a drug from the intravascular triggered drug delivery system, filtering the drug from the blood, and returning the filtered blood to the patient.Type: GrantFiled: May 6, 2019Date of Patent: November 29, 2022Assignee: MUSC Foundation for Research DevelopmentInventors: Dieter Haemmerich, Anjan Motamarry
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Patent number: 11504509Abstract: Embodiments for a cerebrospinal fluid flow detector for detecting the flow of cerebrospinal fluid are disclosed. In some embodiments, the cerebrospinal fluid flow detector includes a casing with a rotatable wheel having a plurality of radially extending arms disposed therein. The rotatable wheel is in communication with a channel having a distal end in communication with an inlet port and a proximal end in communication with an outlet port such that the flow of cerebrospinal fluid through the channel causes the rotatable wheel to rotate. In some embodiments, each radially extending arm includes at least one radiopaque marker in which movement of the rotatable wheel caused by fluid flow through the channel allows an X-ray imaging apparatus to detect the difference in position of a respective radiopaque marker at multiple times caused by rotation of the rotatable wheel.Type: GrantFiled: June 14, 2019Date of Patent: November 22, 2022Assignee: Dignity HealthInventor: John Paul Sheehy
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Patent number: 11491271Abstract: A method controls a device for extracorporeal blood gas exchange. The device has a membrane as a gas-liquid barrier between a bloodstream and a gas stream. The membrane further makes possible a passing over of the carbon dioxide content from the bloodstream into the gas stream. The device has at least one actuator. A change in a value of an operating parameter of the actuator brings about a change in a value of the carbon dioxide content that passes over from the bloodstream into the gas stream. The method further includes providing breathing gas information that indicates a carbon dioxide concentration in breathing gas and providing a control signal, which indicates a request for setting a value of the operating parameter and changing of the value of the operating parameter as a function of the carbon dioxide concentration in the breathing gas.Type: GrantFiled: December 18, 2017Date of Patent: November 8, 2022Assignee: DRÄGER WERK AG & CO. KGAAInventors: Henning Gerder, Karsten Hiltawsky
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Patent number: 11464959Abstract: A method and apparatus are aimed to improve arteriovenous fistula maturation rate by treating the fistula with a crosslink agent solution (fixative solution). The fixative solution will crosslink proteins and biomolecules, allowing formation of crosslinks that stabilize or stable tissue structure. The method and apparatus will address factors that contribute to arteriovenous fistula maturation failure by stopping the neointimal hyperplasia growth after vascular injury and stabilizing the venous wall to prevent the lumen from narrowing.Type: GrantFiled: September 8, 2017Date of Patent: October 11, 2022Assignee: C. R. BARD, INC.Inventor: Hiep Do
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Patent number: 11452804Abstract: A system and method for reducing gas bubbles, including gaseous microemboli (GME) during cardiopulmonary bypass (CPB) by the use of an oxygenator with venous blood bypass and a filter in the venous blood bypass is provided.Type: GrantFiled: July 31, 2017Date of Patent: September 27, 2022Inventor: Keith Gipson
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Patent number: 11433226Abstract: Devices and methods establish and facilitate retrograde or reverse flow blood circulation in the region of the carotid artery bifurcation in order to limit or prevent the release of emboli into the cerebral vasculature such as into the internal carotid artery. The methods are particularly useful for interventional procedures performed through a transcarotid approach or transfemoral into the common carotid artery.Type: GrantFiled: March 12, 2019Date of Patent: September 6, 2022Assignee: Silk Road Medical, Inc.Inventors: Stewart M. Kume, Sieu T. Duong, Michi E. Garrison
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Patent number: 11426503Abstract: Techniques and systems for determining an arteriovenous (AV) fistula maturation in a patient may include detecting a first series of oxygen saturation levels of the patient at a central venous catheter (CVC) associated with a first series of hemodialysis treatments prior to the AV fistula implantation are described. The AV fistula may then be implanted in the patient. A second series of oxygen saturation levels of the patient at the CVC associated with a second series of hemodialysis treatments may be detected. The second series of oxygen saturation levels may be compared to a stable threshold mature AV fistula oxygen saturation level. Among other determinations from the comparison, in response to one or more of the second series of oxygen saturation levels meeting or exceeding the stable threshold mature AV fistula oxygen saturation level, determining the AV fistula is mature. Other embodiments are described.Type: GrantFiled: January 16, 2019Date of Patent: August 30, 2022Assignee: Fresenius Medical Care Holdings, Inc.Inventors: Peter Kotanko, Stephan Thijssen, Hanjie Zhang, Israel Campos
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Patent number: 11426306Abstract: Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allow for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.Type: GrantFiled: February 15, 2019Date of Patent: August 30, 2022Assignee: DOSE MEDICAL CORPORATIONInventors: David S. Haffner, Thomas W. Burns, Harold A. Heitzmann, Kenneth M. Curry
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Patent number: 11400196Abstract: Apparatus and methods for controlled arterial/venous access are provided. The apparatus and methods may include a section of tubing anastomosed to a bodily lumen. A lumen clamping means may utilize a clamp manipulator to effectively seal the tubing, and the manipulator may be operated by two fingers. A needle receptor may be utilized, and the receptor may utilize a rotating member to guide a needle inserted from outside the body, in order ensure accurate placement into a channel. The channel may be in liquid communication with the tubing. The manipulator and the needle receptor may be palpable from outside the body.Type: GrantFiled: February 27, 2019Date of Patent: August 2, 2022Inventor: Tomislav Deur
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Patent number: 11389328Abstract: Devices, methods and kits are described for reducing intraocular pressure. The devices include a support that is implantable within Schlemm's canal and maintains the patency of the canal without substantially interfering with transmural fluid flow across the canal. The devices utilize the natural drainage process of the eye and can be implanted with minimal trauma to the eye. Kits include a support and an introducer for implanting the support within Schlemm's canal. Methods include implanting a support within Schlemm's canal, wherein the support is capable of maintaining the patency of the canal without substantial interference with transmural fluid flow across the canal.Type: GrantFiled: May 15, 2019Date of Patent: July 19, 2022Assignee: SIGHT SCIENCES, INC.Inventors: David Y. Badawi, Paul Badawi
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Patent number: 11369726Abstract: The present disclosure describes for at least two zones of selective thermal therapy of the body. Three-port extracorporeal circuits are described that can be used to establish at least two zones of selective thermal therapy of the body. The example three-port extracorporeal circuit includes a branching section that provides for setting the temperature of blood injected into two different portions of the body at differing temperature levels, to provide. at least two zones of selective thermal therapy.Type: GrantFiled: March 6, 2019Date of Patent: June 28, 2022Assignee: Asia Pacific Medical Technology Development Company, LtdInventor: John R. Gilbert
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Patent number: 11369502Abstract: A gastrointestinal system includes a bracelet type anchor constructed and arranged to reside in a body cavity, a gastrointestinal sleeve configured to expand under a load and contract when the load is removed and a string connecting a bracelet type anchor with the sleeve. Pulling the string transforms the bracelet type anchor from a flexible mode into a rigid state.Type: GrantFiled: March 20, 2019Date of Patent: June 28, 2022Assignee: ALLEVETIX MEDICAL LTD.Inventor: Ziv Kalfon
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Patent number: 11369320Abstract: Graphical user interfaces for use with extracorporeal blood treatment systems may include a human-shaped graphical element and one or more process feature graphical elements. The human-shaped graphical element may be moved automatically or manually by users with respect to the process feature graphical elements to provide indications with respect to the process features corresponding to the human-shaped graphical element and the process feature graphical elements.Type: GrantFiled: June 30, 2016Date of Patent: June 28, 2022Assignee: Gambro Lundia ABInventors: Annmargret Håkansson, Par-Olof Håkansson, Maria Johnsson, Roger Nilsson, Bendik Torvin
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Patent number: 11357898Abstract: The invention is an innovative hybrid venous reservoir designed to receive and store blood during cardiopulmonary bypass (CPB), the hybrid venous reservoir consisting of an air purging chamber that limits air in the venous blood entering the air purging chamber from exiting the air purging chamber in combination with a compliant storage chamber with at least one pliable wall, the combination providing a large volume capacity while limiting the area of the blood-air interface to that of the air purging chamber.Type: GrantFiled: April 15, 2021Date of Patent: June 14, 2022Inventor: Yehuda Tamari
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Patent number: 11357959Abstract: Various systems and methods are provided for reducing pressure at an outflow of a duct, such as the thoracic duct or the lymphatic duct, for example, the right lymphatic duct. A catheter system can be configured to be at least partially implanted within a vein of a patient in the vicinity of an outflow port of a duct of the lymphatic system. The catheter system includes first and second selectively deployable restriction members each configured to be activated to at least partially occlude the vein within which the catheter is implanted and to thus restrict fluid within a portion of the vein. The catheter system includes an impeller configured to be driven by a motor to induce a low pressure zone between the restriction members by causing blood to be pumped through the catheter when the restriction members occlude the vein.Type: GrantFiled: January 12, 2018Date of Patent: June 14, 2022Assignee: White Swell Medical LtdInventors: Yaacov Nitzan, Sagi Raz, Shani Chen, Or Inbar
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Patent number: 11344261Abstract: Devices, systems, and methods herein relate to predicting infection of a patient. These systems and methods may comprise illuminating a patient fluid in a fluid conduit from a plurality of illumination directions, measuring an optical characteristic of the illuminated patient fluid using one or more sensors, and predicting an infection state of the patient based at least in part on the measured optical characteristic.Type: GrantFiled: February 16, 2021Date of Patent: May 31, 2022Assignee: GastroKlenz Inc.Inventors: Eric Hsiang Yu, Aly R. Elbadry, Carlos Rovira Borras, Daniel Elliott Francis
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Patent number: 11337838Abstract: An apparatus comprises a sleeve, a seal, and an anchor assembly. The sleeve is flexible and non-permeable and is configured to fit in a duodenum. The seal is positioned at the proximal end of the sleeve and is configured to seal the proximal end of the sleeve against the stomach mucosa, the pylorus, or the duodenum mucosa. The anchor assembly comprises a pair of atraumatic anchor ends and a resilient member positioned between the anchor ends. At least a portion of the resilient member extends along at least a portion of the length of the sleeve. The resilient member is configured to bias the anchor ends generally toward each other, to thereby substantially anchor the sleeve in the duodenum. The sleeve is configured to prevent chyme from contacting the mucosa of the duodenum; and to prevent enzymes excreted in the duodenum from mixing with chyme in the duodenum.Type: GrantFiled: December 20, 2018Date of Patent: May 24, 2022Assignee: Ethicon Endo-Surgery, Inc.Inventors: Jason L. Harris, Mark S. Zeiner, Adam R. Dunki-Jacobs, Justin W. Sherrill
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Patent number: 11337856Abstract: A method for treating glaucoma with an implantable glaucoma device includes inserting a hollow elongated needle into the eye between the cornea and iris and into the anterior chamber of the eye to form a needle tract in the eye, introducing a distal end of a guidewire through the needle and into the anterior chamber, introducing a snare through a corneal incision into the anterior chamber. The snare has a sheath and a hook or loop inside the sheath and extendible therefrom. The method includes capturing a segment of the guidewire proximate the distal end of the guidewire with the snare within the anterior chamber, removing the needle from over the guidewire outside of the eye, coupling a glaucoma drainage device to a proximal end of the guidewire that extends outside of the eye, and pulling on the captured guidewire segment with the snare to pull the glaucoma drainage device into the needle tract and into the anterior chamber of the eye until the glaucoma device is located in an implanted position in the eye.Type: GrantFiled: January 28, 2019Date of Patent: May 24, 2022Assignee: InnFocus, Inc.Inventors: Leonard Pinchuk, John B. Martin, Anh Le