Abstract: A therapeutic agent for intervertebral disc degeneration that contains LASCol obtained by enzymatically cleaving a terminus of collagen.

Abstract: A seafood opener comprising a fork located on a first end configured to remove shells from seafood. The fork is further configured to be used as a hammer to crack the shells of seafood. A second end of the seafood opener includes a pry blade configured to pry oysters or clams open in order to access the meat inside. A bottle opener is also located on the first end of the seafood opener.

Abstract: A positive resist composition comprising a base polymer comprising repeat units having the structure of a sulfonium salt of a substituted or unsubstituted salicylic acid exhibits a high sensitivity, high resolution, low edge roughness and small size variation, and forms a pattern of good profile after exposure and development.

Abstract: The present invention relates to alpha-amylase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

Abstract: A device comprises an enclosure having a rear opening adapted to receive a light beam from a light source, a front opening adapted to emit a modified light beam, and internal walls extending between the rear opening and the front opening. The light beam is modified according to a perimeter of the front opening. A light shaping assembly comprises a two-dimensional array formed of a plurality of such devices, each one of the plurality of devices being adapted to receive a light beam from a corresponding light source.

Abstract: Intra-oral formulations comprising soft anticholinergic alkyl esters are useful for treating excessive drooling conditions in subjects, such as humans, suffering from sialorrhea. Preferably, at least one soft anticholinergic ester is provided in an effective amount or concentration in an anhydrous intra-oral formulation that can inhibit excessive drooling resulting from a condition known as sialorrhea.

Abstract: Compositions, methods, and uses are contemplated in which a betalain-containing preparation is administered to a mammal to enhance athletic performance. Most preferably, the preparations are substantially nitrate free and acutely and transiently increase hematocrit, erythropoietin, adrenalin, and beta endorphin, while reducing serum lactate, serum lactate dehydrogenase, heart rate and a rate of perceived exertion.

Abstract: The invention provides compounds of formula I, wherein the substituents are as set out in further detail in the specification. The compounds are potent inhibitors of GCN2 and they have excellent pharmacokinetic properties. The compounds are useful for the treatment or prevention of a variety of conditions, particularly cancer. The invention further provides pharmaceutical compositions comprising the compounds of the invention and uses of the compounds and the compositions.

Abstract: A test device and method for testing a distributed feedback laser diode (DFB-LD) device for an optical transceiver of a radio over fiber (RoF) system examines the DFB-LD device based on an absolute limiting rating, an operating case environment, and a functional specification, in which the absolute limiting rating is a rating at which there is no fatal damage to the DFB-LD device during a short period of time when each limiting parameter is isolated and all other parameters are in a normal performance parameter, the operating case environment includes an operating temperature, and the functional specification includes parameters to be tested according to an operating condition for the functional specification.

Abstract: There is provided an optical network device (30) comprising separate downstream and upstream signal paths (33, 34) disposed between a wavelength division multiplexing unit (16) and a signal splitting element (32, 44, 50), an optical to electrical signal converter (18) disposed in the downstream path and an electrical to optical signal converter (22) disposed in the upstream path, wherein the signal splitting element (32, 44, 50) is capable of splitting signals independent of signal frequency and is configured with an isolation of 30 to 50 dB thereby to substantially prevent leakage of downstream signals into upstream path (34). The signal splitting element is capable of splitting signals independent of signal frequency and may be a directional coupler, two-way signal splitter or hybrid coupler comprising at least two different types of coupler element.

Abstract: A service mapping processing method for an optical transport network, an apparatus, and a system are provided, where the method includes: generating mapping adaptation indication information according to a mapping granularity of a to-be-carried LO ODU, where the mapping granularity is M×g bytes, M is a quantity of timeslots occupied by the to-be-carried LO ODU in an OPUCn, g is a size of a mapping granularity corresponding to each timeslot of the timeslots occupied by the LO ODU, and g is a positive integer greater than 1; mapping, according to the mapping adaptation indication information, the to-be-carried LO ODU to an ODTUCn.M payload area; encapsulating the mapping adaptation indication information into the ODTUCn.M overhead area; encapsulating the ODTUCn.M into an OTUCn; and sending the OTUCn to a receive end device. The method avoids that OTUCns that use different mapping granularities cannot interwork between a receive end and a transmit end.

Abstract: Provided herein are polynucleic acids and expression vectors for the expression and secretion of angiotensin peptide fragments (e.g., angiotensin-(1-7)) in probiotic bacteria. Provided herein are also probiotic compositions that enable efficient, cost-effective and patient friendly oral therapeutics for treating diverse pathological conditions that involve the renin-angiotensin system (RAS), e.g., pulmonary hypertension, diabetes, diabetic complications, cardiovascular diseases, and ocular inflammatory and neurodegenerative diseases.

Abstract: A method performed by a network node for handling a communication session in a wireless communication network. The network node receives from a user equipment (UE) a registration message for re-registering the UE to a session. The network node further verifies the registration message based on registration information previously stored for the UE When verified in response to the reception, transmits back to the UE, a registration response along with a terminating request for a call establishment.

Abstract: Systems, methods, and devices that relate to an automated auditing system of the network conditions are disclosed. In one example aspect, a network device in a core network for wireless communication include one or more processors that are configured to determine an expected network state based on predefined configuration information of one or more network resources, receive measurement results reported by one or more wireless devices via at least one radio access node, estimate an actual network state based on the measurement results reported by one or more wireless devices, and detect a discrepancy between the expected network state and the actual network state.

Abstract: In accordance with an example embodiment of the present invention, a method comprising: receiving from a network node, by a user equipment of a plurality of user equipment associated with more than one communication beam of a communication network, information comprising locations in time of the user equipment during paging occasions with at least one cell of the communication network associated over more than one communication beam, wherein the information identifies any provided order of the more than one communication beam covering the locations in time of the user equipment during the paging occasions; and based on the information, identifying by the user equipment at least one communication beam and timing of at least one paging occasion, of the paging occasions, for the user equipment.

Abstract: Disclosed are a positioning method in a wireless communication system, and a device for supporting same.

Abstract: The present disclosure relates to a communication technique which combines a 5G communication system, for supporting a higher data transmission rate than 4G systems, with IoT technology, and a system for same. The present disclosure may be applied to intelligent services (for example, smart homes, smart buildings, smart cities, smart cars or connected cars, health care, digital education, retailers, security and safety-related services, or the like) on the basis of 5G communication technology and IoT-related technology. Disclosed is a method for providing subscription information about non-public networks to a terminal in a wireless communication system.

Abstract: The string trimmer includes a connecting rod, a string trimmer head, and an operation part. The string trimmer head includes a trimmer line, a spool, a housing, and a streamlined protection structure. The spool is configured to wind the trimmer line and is capable of rotating about a first axis. The housing has an accommodating cavity for accommodating at least part of the spool and a threading hole for the trimmer line to extend to an outer side of the housing. The protection structure includes a head, a tail and a passage through which the trimmer line penetrates. The head is connected to the housing, the tail extends on the outer side of the housing, and the passage is configured to accommodate the trimmer line penetrating through the threading hole and expose the trimmer line out of the tail of the protection structure.

Abstract: Provided is Lactobacillus paracasei TCI727, deposited in the Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ) with a deposit number of DSM 33756. A method for improving calcium absorption of a subject in need thereof by using the Lactobacillus paracasei TCI727 or metabolites thereof is also provided. The method includes administering to the subject an effective amount of a composition comprising the Lactobacillus paracasei TCI727 or the metabolites thereof.

Abstract: In one aspect, the disclosure relates to methods and compositions for treatment of cancer cachexia. In a further aspect, the composition is a pharmaceutical composition comprising a class I/IIB HDAC inhibitor and an androgen. In a still further aspect, the method of treatment comprises administering a class I/IIB HDAC inhibitor and an androgen to a subject or patient who has been diagnosed as having cancer cachexia. In some aspects, the class I/IIB HDAC inhibitor is a compound known as AR-42.