Abstract: An apparatus is for localizing brain tissue regions connected with a brain function in a brain operating field. The apparatus includes a stimulation apparatus and a localization unit with a camera. The stimulation apparatus is configured to carry out a number of stimulation cycles. Each cycle includes a stimulation phase during which the brain function is stimulated and a rest phase during which there is no stimulation of the brain function. The localization unit records at least one stimulation image with the stimulated brain function and at least one reference image without the stimulated brain function during each stimulation cycle and uses the recorded stimulation and reference images to localize the brain tissue regions connected with the stimulated brain function. The stimulation apparatus is configured to output a feedback signal to the localization unit with at least the start of a stimulation cycle being evident from the feedback signal.
Type:
Grant
Filed:
September 18, 2020
Date of Patent:
September 5, 2023
Assignee:
Carl Zeiss Meditec AG
Inventors:
Christoph Hauger, Gerald Panitz, Roland Guckler
Abstract: Techniques are disclosed for systems and methods to provide improved ocular aberrometry recovery. An ocular aberrometry system includes a wavefront sensor configured to provide wavefront sensor data associated with an optical target monitored by the ocular aberrometry system and a logic device configured to communicate with the wavefront sensor. The logic device is configured to receive ocular aberrometry output data including at least the wavefront sensor data provided by the wavefront sensor, identify imaging artifact induced singularities in the received ocular aberrometry output data, determine corrected aberrometry output data based, at least in part, on the identified singularities and the received ocular aberrometry output data, and generate user feedback corresponding to the received ocular aberrometry output data based, at least in part, on the corrected aberrometry output data.
Type:
Grant
Filed:
September 25, 2020
Date of Patent:
August 22, 2023
Assignee:
Alcon Inc.
Inventors:
Max Hall, Thomas Padrick, Edwin Jay Sarver
Abstract: One or more triggers, fluorescence or auto-fluorescence triggers, NIRAF triggers, methods of using triggers, fiber optic rotary joints (FORJ), free space beam combiners, OCT, SEE and/or fluorescence devices and systems for use therewith, methods of using and/or manufacturing same and storage mediums are provided. One or more embodiments using one or more triggers achieve structural compactness and/or high-speed acquisition while avoiding or reducing the need for high computational power. One or more embodiments use one or more triggers, one or more fluorescence triggers, one or more auto-fluorescence triggers, or NIRAF triggers, and/or one or more rotary joints, for performing pullback and/or image recording.
Abstract: A vibration transmitter includes: a first rod including a fitting hole extending along the longitudinal axis thereof; and a second rod attached to a distal end portion of the first rod by a fitting portion fitted into the fitting hole in a state where a compressed surface pressure is received from the inner surface of fitting hole. The first rod includes: a first region in which the fitting portion is fitted into the fitting hole; and a second region positioned proximal of the first region. In the first region of the first rod, a crystal grain diameter is larger than that in the second region of the first rod.
Abstract: Vasculature or parenchyma is imaged using upright MRI techniques, on patients who may have conditions such as congestive heart failure, or otherwise be healthy. When an individual is horizontal, venous drainage is minimized, causing the vessels to remain engorged, also referred to herein as vascular congestion. Vascular congestion results in an enlarging of the vessels and surrounding tissue causing the vessels to be more visible on MRIs. The decrease in vascular visibility in upright subjects is in part, due to an increase in venous drainage. Patients suffering from coronary and/or pulmonary deficiencies (e.g. CHF) experience decreased rates and degrees of venous drainage. In one embodiment, the present invention uses upright imaging to visualize these enlarged vessels.
Abstract: The purpose of the present invention is to provide a technique whereby multiple projection targets are efficiently identified from multiple neurons in multiple brain areas with the use of multis-point light stimulation. An acquisition unit 52 acquires spike signals generated from multiple neurons existing in the vicinity of two or more recording sites. A stimulation control unit 51 selects one projection target candidate from two or more candidates in accordance with a definite system on the basis of the spike signals and then determines irradiation timing of light stimulation. Upon the light stimulation, a management unit 53 acquires the spike signals in all of the recording sites within a definite period of time before or after the light stimulation, while dividing the spike signals into anti responses and collision responses. An anti response management unit 81 acquires and manages information relating to the anti responses.
Abstract: A device for cooling the skin tissue of a patient during a procedure using energy includes a mat-like structure, the mat-like structure having a bottom wall, a top wall and upstanding walls connecting the top wall and the bottom wall, the walls defining an enclosed volume; it also includes one or more electrodes positioned to protrude from the bottom wall and extend through the volume for connection to a source of energy; further, the volume defines a space for holding a cooling substance for cooling the one or more electrodes and the skin tissue during an energy-based procedure.
Abstract: The present disclosure provides a cuboid magnetometer with high fluorescence collection efficiency, used for cardiac magnetic field measurement, and based on nitrogen-vacancy (NV) centers in diamond, and a cardiac magnetic field measurement system. The cardiac magnetic field measurement system includes a magnetic shielding chamber, a non-magnetic bed, an array probe for cardiac magnetic field measurement, a three-axis displacement platform, a high-speed data collection card, a fiber laser source, a microwave source, and a computer. The array probe for cardiac magnetic field measurement includes a non-magnetic shell, a stepping motor, a porous rotary fiber coupling apparatus, a fiber bundle set, a special photodetector (PD) set, a filter set, a ring-shaped antenna, and special diamond.
Type:
Grant
Filed:
May 22, 2021
Date of Patent:
June 20, 2023
Assignee:
North Univeristy of China
Inventors:
Zongmin Ma, Jun Liu, Li Qin, Xiaoming Zhang, Doudou Zheng, Yunbo Shi, Jun Tang, Hao Guo, Xiaocheng Wang
Abstract: A flexible circuit that is substantially planar may be assembled into an electrophysiologic catheter. The flexible circuit may include various location sensing portions and force sensing portions. The flexible circuit may be deformed in a manner that improves the catheter's functionality concerning force feedback and location feedback, and then further deformed to be assembled into a small volume of the catheter.
Type:
Grant
Filed:
July 16, 2018
Date of Patent:
June 13, 2023
Assignee:
BIOSENSE WEBSTER (ISRAEL) LTD.
Inventors:
Christopher T. Beeckler, Joseph T. Keyes, Kevin J. Herrera
Abstract: Examination of the structure and function of blood vessels is an important means of monitoring the health of a subject. Such examination can be important for disease diagnoses, monitoring specific physiologies over the short- or long-term, and scientific research. This disclosure describes technology and various embodiments of a system and method for imaging blood vessels and the intra-vessel blood flow, using at least laser speckle contrast imaging, with high speed so as to provide a rapid estimate of vessel-related or blood flow-related parameters.
Type:
Grant
Filed:
May 28, 2021
Date of Patent:
June 6, 2023
Assignee:
Vasoptic Medical Inc.
Inventors:
Abhishek Rege, M. Jason Brooke, Kartikeya Murari, Yusi Liu
Abstract: A medical system comprises a memory for receiving intraoperative external image data for at least a portion of a patient anatomy. The memory further receives intraoperative pose data for a medical instrument of the medical system. The medical system further comprises a processor configured for generating a first model of the patient anatomy. The processor is further configured for, based on the intraoperative external image data, intraoperatively generating an updated model of the patient anatomy that is different from the first model. The updated model includes an anatomical structure that is not present in the first model.
Type:
Grant
Filed:
October 20, 2020
Date of Patent:
June 6, 2023
Assignee:
INTUITIVE SURGICAL OPERATIONS, INC.
Inventors:
Dorin Panescu, Prashant Chopra, Jonathan M. Sorger, Tao Zhao
Abstract: A method for detecting fluid injection in a patient, the method including the steps of providing a fluid storage tank; providing fluid for use in machinery and adding said fluid to the fluid storage tank; and providing a fluorescent dye and adding the fluorescent dye to the fluid such that the fluid fluoresces in the presence of ultraviolet light.
Abstract: A portable magnetic resonance imaging (MRI) system and methods, involving a magnet configured to generate a magnetic field, the magnet being a portable magnet transportable on a cart, and at least one coil assembly disposed in relation to the magnet, the at least one coil assembly having at least one gradient coil.
Type:
Grant
Filed:
July 22, 2020
Date of Patent:
May 30, 2023
Inventors:
Cameron Anthony Piron, Alexander Gyles Panther, Sheryl Rae Thingvold, Chad Tyler Harris, Jeff Alan Stainsby
Abstract: The disclosure provides for a systems and methods for monitoring uterine contractions of a uterus of a mammal by reconstructing three-dimensional images of uterine surface electrical activity based on a noninvasively obtained body-uterus geometry and a plurality of body surface electrical potential maps.
Type:
Grant
Filed:
February 5, 2020
Date of Patent:
May 30, 2023
Assignee:
Washington University
Inventors:
Alison G. Cahill, Phillip S. Cuculich, Yong Wang, Alan Schwartz
Abstract: Arrangements, apparatus, systems and systems are provided for obtaining data for at least one portion within at least one luminal or hollow sample. The arrangement, system or apparatus can be (insertable via at least one of a mouth or a nose of a patient. For example, a first optical arrangement can be configured to transceive at least one electromagnetic (e.g., visible) radiation to and from the portion. A second arrangement may be provided at least partially enclosing the first arrangement. Further, a third arrangement can be configured to be actuated so as to position the first arrangement at a predetermined location within the luminal or hollow sample. The first arrangement may be configured to compensate for at least one aberration (e.g., astigmatism) caused by the second arrangement and/or the third arrangement. The second arrangement can include at least one portion which enables a guiding arrangement to be inserted there through.
Type:
Grant
Filed:
December 22, 2020
Date of Patent:
May 30, 2023
Assignee:
The General Hospital Corporation
Inventors:
Guillermo J. Tearney, Milen Shishkov, Brett Eugene Bouma, Benjamin J. Vakoc, Norman S. Nishioka
Abstract: Ultrasound devices and methods are described, including a repeatable ultrasound transducer probe having ultrasonic transducers and corresponding circuitry. The repeatable ultrasound transducer probe may be used individually or coupled with other instances of the repeatable ultrasound transducer probe to create a desired ultrasound device. The ultrasound devices may optionally be connected to various types of external devices to provide additional processing and image rendering functionality.
Type:
Grant
Filed:
March 22, 2021
Date of Patent:
May 16, 2023
Assignee:
BFLY OPERATIONS, INC.
Inventors:
Jonathan M. Rothberg, Keith G. Fife, Nevada J. Sanchez, Tyler S. Ralston, Gregory L. Charvat, Gregory Corteville
Abstract: A system for optical coherence tomography includes a source of optical radiation, an optical fiber, and a graded index fiber attached to a distal end of the optical fiber. The optical fiber and the graded index fiber are together configured to provide a common path for optical radiation reflected from a reference interface at a distal end of the graded index fiber and from a target.
Abstract: A method and apparatus for pre-processing a photoplethysmogram (PPG) signal include receiving, by an apparatus, the PPG signal including a plurality of pulses, obtaining, by the apparatus, a smoothed PPG signal based on smoothing the PPG signal using a moving average filter, obtaining, by the apparatus, a drift removed PPG signal based on removing drift from the smoothed PPG signal using a fitted polynomial function, and obtaining, by the apparatus, a rectified PPG signal based on correcting a motion artifact of the drift removed PPG signal by replacing each of the plurality of pulses using a combination of a global signal pulse and a corresponding local signal pulse.
Type:
Grant
Filed:
January 22, 2020
Date of Patent:
May 9, 2023
Assignee:
SAMSUNG ELECTRONICS CO., LTD.
Inventors:
Ibrahim Abdul Majeed, Sujit Jos, Rahul Arora, Ka Ram Choi, Sang Kon Bae
Abstract: Blood pressure detection apparatuses and methods for detecting a blood pressure of a user are described comprising optical sensors/detectors and a force sensor and, in some embodiments, comprising only a force sensor, measuring force applied by a finger. Blood pressure is measured by applying an increasing (or decreasing) force or pressure with a finger of the user on at least the force sensor, which, in some embodiments, may be a plurality of increasing pressure steps, each step being held within a predetermined acceptable pressure/force tolerance range for a predetermined hold time, and measuring the force applied by the finger and, in some embodiments, optically measuring the blood in a vessel in the finger relating to the applied pressure/force. Feedback (visual, haptic, sound) of the applied pressure is provided to the user.