Abstract: The invention provides a magnetic inductive sensing device (30) comprising a loop antenna (10) for inductively coupling with electromagnetic (EM) signals emitted from a medium in response to stimulation of the medium with electromagnetic excitation signals. The device includes an electromagnetic shield (36) element which is arranged such as to intercept electromagnetic signals travelling to or from the antenna. The shield element is formed of conductive material such as to block electrical field components of incident signals but further incorporates a non-conductive gap in the material so as to prevent the formation of eddy currents. A loop of the antenna is broken by an opening, the opening being bridged by a capacitor, and the device comprises a signal processing means which is electrically coupled to the antenna via only a single point of the antenna, located to one side of the opening.

Abstract: Systems and methods are provided for motion corrected wide-band pulse inversion ultrasonic imaging. A first pulse is transmitted, a second pulse is then transmitted after a delay, with the second pulse having different polarity. Echoes of the first pulse and the second pulse are received, using a reception bandwidth that enables capturing at least a portion of a fundamental portion of each pulse. The echoes are processed, and corresponding ultrasound images are generated based on processing. The processing includes determining displacement data between the first pulse echo and the echo of the second pulse for at least one structure in an imaged area; determining one or more displacement corrections based on the displacement data; applying at least one displacement correction to at least one of the first pulse echo and the echo of the second pulse; and combining the first pulse echo and the echo of the second pulse.

Abstract: Methods for treating and managing pain in a patient with therapeutic neuromodulation and associated systems and methods are disclosed herein. Chronic or debilitating pain can be associated, for example, with a disease or condition of the abdominal or reproductive viscera. One aspect of the present technology is directed to methods that at least partially inhibit sympathetic neural activity in nerves proximate a target blood vessel of a diseased or damaged organ of a patient experiencing pain. Targeted sympathetic nerve activity can be modulated at least along afferent pathways which can improve a measurable parameter associated with the pain of the patient The modulation can be achieved, for example, using an intravascularly positioned catheter carrying a therapeutic assembly, e.g., a therapeutic assembly configured to use electrically-induced, thermally-induced, and/or chemically-induced approaches to modulate the target sympathetic nerve.

Abstract: Disclosed herein are a surgical system for patella tracking and a method for selecting a properly-sized patellar implant utilizing the same. The surgical system may include first and second trackers and a patellar tracking system. The first tracker may be configured to contact an unresected or a resected patella, and the second tracker may be configured to contact a bone. The patellar tracking system may be configured to track the first and second trackers during patellar flexion and extension to generate patellar range of motion and patellar trial range of motion. A method for selecting a patellar implant may utilize the first and second trackers and the patellar tracking system.

Abstract: An automatic method of categorizing the contact force of a catheter tip against a portion of a patient's heart based on motion of the catheter tip, the method comprising (a) capturing a series of 3D-coordinate data points of the catheter tip as a function of discrete times with a 3D medical imaging system, the 3D coordinates corresponding to an orthogonal 3-axis spatial coordinate system, (b) using a programmable computing system, computing a set of measures based on the series of 3D-coordinate data points, (c) categorizing each measure by a respective set of predetermined threshold values; and (d) combining the categorized measures to yield a relative quality of the contact force.

Abstract: Uptake of hypoxia-sensitive PET tracers is dependent on tissue transport properties, specifically, distribution volume. Variability in tissue transport properties reduces the sensitivity of static PET imaging to hypoxia. When tissue transport (vd) effects are substantial, correlations between the two methods of determining hypoxic fractions are greatly reduced—that is, trapping rates k3 are only modestly correlated with tumour-to-blood ratio (TBR). In other words, the usefulness of dynamic- and static-PET based hypoxia surrogates, trapping rate k3 and TBR, in determining hypoxic fractions is reduced in regions where diffusive equilibrium is achieved slowly. A process is provided for quantifying hypoxic fractions using a novel biomarker for hypoxia, hypoxia-sensitive tracer binding rate kb, based on PET imaging data. The same formalism can be applied to model the kinetics of non-binding CT and MT contrast agents, giving histopathological information about the imaged tissue.

Abstract: A system for differentiating between magnetic field distortion and physical movement in a hybrid magnetic and impedance tracking system can comprise a first drive patch and a second drive patch configured to generate an electrical field within the body for locating an electrode on the medical device, a magnetic localization system configured to generate a magnetic field, a magnetic sensor configured to receive signals from the magnetic localization system, and an electronic control unit configured to receive location data from the impedance localization system and magnetic sensor location data from the magnetic localization system. The electronic control circuit can be configured to detect a location change of the magnetic sensor and use the drive patch location data and magnetic sensor location data to determine whether the detected location change of the magnetic sensor is caused by a magnetic field distortion or a physical movement of the magnetic sensor.

Abstract: A method for fabricating an intravascular imaging assembly is provided. In one embodiment, the method includes forming a stacked structure (415) having a plurality of sacrificial material layers disposed between a plurality of ultrasound material layers in an alternating pattern; dicing the stacked structure (420) to form a plurality of elongated strips, each comprising an array of ultrasound elements defined by the plurality of ultrasound material layers and spacers defined by the plurality of sacrificial material layers; coupling a first elongated strip (430) of the plurality of elongated strips to a flexible circuit substrate; and removing the spacers (435) of the first elongated strip from the flexible circuit substrate.

Abstract: Provided are an ultrasound imaging apparatus and a method of processing an ultrasound image. The ultrasound imaging apparatus includes a display configured to display a moving image consisting of a plurality of ultrasound images that are played back according to a time order together with at least one icon, corresponding to at least one piece of change information for changing a display of at least one of the plurality of ultrasound images, in association with the time order.

Abstract: The invention provides a magnetic inductive sensing system for sensing electromagnetic signals emitted from a body in response to electromagnetic excitation signals applied to the body. The electromagnetic signals are generated and sensed by the same loop resonator which comprises a single-turn loop antenna and a tuning capacitor. The loop antenna of the resonator and a signal generation means for exciting the resonator to generate excitation signals are together configured so as to optimize the value of a ratio between the radial frequency of the generated electromagnetic excitation signals and a reference frequency of the antenna, where the reference frequency is the frequency for which one wavelength of the generated excitation signals (waves) matches the circumferential length of the antenna. This ratio, which corresponds to a normalized radial frequency of the generated excitation signals, is maintained between a value of 0.025 and 0.50.

Abstract: Methods and systems of computing parameter values of one or more model parameters are described. The model models structural and dielectric properties of a structure in a human or an animal body. An exemplary method includes: accessing voltage measurements made at different places in the vicinity of the structure by one or more in-body field sensing electrodes in response to currents applied to one or more field supplying electrodes; and computing the parameter values by adjusting the parameter values to fit predicted voltage values to the accessed voltage measurements, wherein the predicted voltage values are predicted from the model for the currents applied to the field supplying in-body electrodes.

Abstract: Diagnostic apparatus includes a plurality of antennas, which are configured to be disposed at different, respective locations on a thorax of a living body so as to direct radio frequency (RF) electromagnetic waves from different, respective directions toward a heart in the body and to output RF signals responsively to the waves that are scattered from the heart. Processing circuitry is configured to process the RF signals over time so as to provide a multi-dimensional measurement of a movement of the heart.

Abstract: In some embodiments, a body cavity shape of a subject is reconstructed based on intrabody measurements of at least one property of an electromagnetic field by an intrabody probe (for example, a catheter probe) moving within a plurality of electrical fields intersecting the body cavity. In some embodiments, the electrical fields are generated at least in part from electrodes positioned in close proximity, for example, within 1 cm, of the body cavity. In some embodiments, the body cavity is a chamber of a heart (for example, a left atrium or left ventricle), and the electrodes used to generate the electrical field are positioned in the coronary sinus, a large vein occupying the groove between the left atrium and left ventricle. In some embodiments, known distances between measuring electrodes are used in guiding reconstruction, potentially overcoming difficulties of reconstruction from measurements of non-linear electrical fields.

Abstract: A method for automatically selecting a calculation depth range upon measuring a property of a viscoelastic medium, the depth range being selected from P possible ranges, includes calculating, from the ultrasound signal acquired using a probe for elastography, the property of the viscoelastic medium in at least one of the P depth ranges as well as the distance between the probe and the wall of the viscoelastic medium; determining the validity of at least one of the P calculation depth ranges; determining the validity of the calculation of the property of the viscoelastic medium over the valid calculation depth range or ranges; selecting, from the values of the property of the viscoelastic medium the calculation of which is valid at the valid depth ranges, a depth range fulfilling a selection criterion.

Abstract: Systems and methods for creating planar cuts on a bone are provided utilizing one or more cutting guides assembled to a plurality of bone pins, where the bone pins are inserted on the bone coincident with one or more virtual pin planes defined relative to one or more of the planar cuts. Alignment guides are also disclosed herein that aid in the creation of pilot holes for receiving a cutting block in a desired position and orientation (POSE). An articulating surgical device actively positions the bone pins coincident with the virtual plane to ensure the cutting guides, when assembled to the pins, aligns one or more guide slots in the desired POSE to create the planar cuts.

Abstract: Systems and methods for hyperspectral analysis of cardiac tissue are provided. In some embodiments, a method for visualizing ablation lesions includes illuminating at one or more illumination wavelengths a surface of tissue having an ablation lesion; collecting a spectral data set comprising spectral images of the illuminated tissue acquired at multiple spectral bands each at one or more acquisition wavelengths; distinguishing between the ablation lesion and an unablated tissue based on one or more spectral differences between the ablation lesion and unablated tissue; and creating a composite image of the tissue showing the ablation lesion and the unablated tissue.

Abstract: A system for operating third party proprietary software on a medical monitoring device operating native proprietary software and a system for obtaining compatible third party proprietary software for operation on the monitoring device.

Abstract: The apparatus is adapted to detect a tool based on a 3D image obtained by a 3D ultrasound imaging system. The apparatus comprises an image processing unit, which includes a tool detection module configured to perform a tool detection procedure. The tool detection procedure involves identifying a shadow of the tool in the 3D image and calculating the position of a “tool plane section” of the 3D image in which the entire length of the tool is represented.

Abstract: An intravascular imaging device (102) is provided. In some embodiments, the intravascular imaging device includes a flexible elongate member sized and shaped for insertion into a vessel of a patient, the flexible elongate member having a proximal portion and a distal portion; and an imaging assembly (110) disposed at the distal portion of the flexible elongate member, the imaging assembly including a flex circuit (214) positioned directly around the flexible elongate member. In some embodiments, a method of assembling an intravascular imaging device includes obtaining a flex circuit including a first layer having a plurality of transducers and a second layer having an acoustic backing material; and positioning the flex circuit directly around a distal portion of a flexible elongate member.

Abstract: Embodiments can relate to a method for detecting a physiological condition by generating a Magnetic Resonance Image (MRI) contrast image comprising a T1 weighted (T1W) image/T2 weighted (T2W) ratio. Embodiments can further include using the T1W/T2W ratio to identify changes in substantia nigra pars compacta within a region of the brain.