Abstract: A compound of the formula; ##STR1## wherein R.sup.1 is an amino group which may be protected, R.sup.3 is a hydrogen atom or an optionally substituted hydrocarbon residue; Z is S, S.fwdarw.O, O or CH.sub.2, R.sup.4 is a hydrogen atom, methoxy group or formamido group, R.sup.13 is a hydrogen atom, methyl group, hydroxyl group or halogen atom and A.sym. is an optionally substituted imidazolium-1-yl group forming a condensed ring at the 2,3- or 3,4-position or a pharmaceutically acceptable salt or ester thereof is novel and has excellent antibacterial activity.

Abstract: The novel UV-absorbers are compounds of the formula ##STR1## in which R.sup.1 is, for example, hydrogen, n is one of the numbers 1 or 2 and R.sup.2 is an appropriate monovalent or divalent radical, for example --OH or --O--CH.sub.2 CH.sub.2 --O--. The UV-absorbers are used in particular for stabilising and improving lacquers and photographic material.

Abstract: N.sub.1 -substituted 1H-benzotriazole hydroxyethyl sulfone compounds, a process for their preparation and their use for the preparation of dyestuffs. Compounds of the general formula ##STR1## in which R is hydrogen or alkyl which has 1 to 6 carbon atoms and can be substituted by hydroxy, sulfo, carboxy, phosphono and/or cyano, W denotes a divalent, optionally substituted aliphatic radical, (C.sub.5 -C.sub.10)-cycloaliphatic radical which is optionally substituted by alkyl, aliphatic-(C.sub.5 -C.sub.8)-cycloaliphatic radical which is optionally substituted by alkyl, optionally substituted araliphatic radical or optionally substituted aromatic carbocyclic radical, it being possible for the aliphatic radicals in W to be interrupted by hetero groups of the formulae --O--, --S--, --SO.sub.

Abstract: Novel capped polymeric quaternary ammonium compositions formed by reacting ionene type polymers with tertiary amines are useful as microbicides, corrosion inhibitors, debonding agents, flocculants, softeners, plant growth regulators, and demulsifiers.

Abstract: Substituted 4-quinoline-carboxylic acids useful in the treatment of arthritis and inhibition of progressive joint deterioration are disclosed together with methods of use and synthesis thereof.

Abstract: A process is provided for the purification to highly purified states of 5-pyrimidinecarboxamides which are essentially insoluble in both organic and inorganic solvents. The 5-pyrimidinecarboxamide to be purified is contacted with an organic base having a pKa value in excess of 6.95 to form an adduct. The adduct is purified through recrystallization and the desired 5-pyrimidinecarboxamide is regenerated from the adduct in highly purified form with acid. Additionally, an adduct resulting from the combination of a 5-pyrimidinecarboxamide with such an organic base is provided, which adduct is capable of being purified using recrystallization techniques, where the 5-pyrimidinecarboxamide is not itself capable of being so purified due to its relative insolubility in organic and inorganic solvents.

Abstract: Compounds of the formulas: ##STR1## wherein Het is an oxazole or oxazine moiety; X is O, S or SO, n is an integer from 3 to 9, Y is an aliphatic bridge; and the various R groups represent hydrogen or various substituents as described herein, are useful as antiviral agents, especially against picornaviruses. N-(Chloroalkyl)amide intermediates for the compounds of Formula I are also active as antiviral agents. Related compounds outside the scope of the above formulas are also disclosed.

Abstract: This invention relates to a method for preparing 2-phenylbenzotriazoles having the formula I, ##STR1##

Abstract: This invention pertains generally to substituted 2-methylisoxazolines and more specifically to 3,5-diphenyl-3-[(1H-imidazol-1-ylmethyl) or (1H-1,2,4-triazol-1-yl-methyl)]-2-methyl-4-isoxazoline derivatives which are useful as antifungal agents.

Abstract: The present invention is directed to novel sulfonylurea compounds, compositions and methods for controlling bolting in sugar beets.

Abstract: Thermosettable prepolymers or resins are prepared by reacting (1) a pyrazine compound containing at least two substituent groups which have a hydrogen atom attached to a carbon atom which is attached to the ring such as tetramethylpyrazine, (2) a material containing at least two aromatic aldehyde groups, and (3) at least one of (a) a nitrogen containing aromatic heterocyclic compound containing at least one hydrogen atom attached to a carbon atom attached to the ring and a polymerizable unsaturated group such as 2-methyl-5-vinylpyridine or (b) an aldehyde containing at least one polymerizable unsaturated group such as 4-isopropenyl-1-cyclohexane-1-carboxaldehyde. These prepolymers or resins are curable to thermoset products having good mechanical and thermal properties by heat and pressure or by homopolymerization or copolymerization with N,N'-bis-imides such as 1,1'-(methylenedi-4,1-phenylene)bismaleimide. The prepolymers are suitable for preparing composites.

Abstract: 5-alkyl(or alkenyl)-3-phenyl-3-(1H-imidazol-1-ylmethyl) -2- methylisoxazolidines and related derivatives in which hydrogens of their phenyl rings can be replaced by halogen, lower alkyl or lower alkoxy groups are useful as antifugal agents.

Abstract: An oxazolidine having the formula ##STR1## wherein R is selected from the group consisting of alkyl, substituted alkyl, alkenyl, cycloalkyl, benzyl, alkoxyalkyl, carboalkoxyalkyl, alkylthioalkyl, phenyl, substituted phenyl, furanyl, phenoxyalkyl, carboalkoxy, substituted phenoxyalkyl, alkylamino, alkoxy, chloroethylamino, alkylthio, cycloalkylalkyl, cycloalkenylalkyl, phenylamino, substituted phenylamino, alkenylamino, and benzylamino; Z is selected from the group consisting of oxygen or sulfur; R.sub.1 is selected from the group consisting of alkyl or halosubstituted alkyl wherein the alkyl group has from 1 to 4 carbon atoms; and X and Y are the same or different and are selected from the group consisting of trifluoromethyl, chloro, bromo, fluoro, hydrogen, cyano, alkyl, thioalkyl, halothioalkyl, alkoxy and sulfonylalkyl, wherein the alkyl groups in each alkyl-containing moiety have from 1 to 4 carbon atoms. Also disclosed is a method of use.

Abstract: Novel pyrazolo[3,4-d]pyrimidine derivatives represented by the general formula (I) ##STR1## wherein R.sup.1 is an aryl or heteroaryl group which may be substituted by one to three members selected from the class consisting of halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, nitro, amino, N-C.sub.1-4 alkylamino, N,N-diC.sub.1-4 alkylamino, hydroxy, trifluoromethyl, carbamoyl, N-C.sub.1-4 alkylcarbamoyl and N,N-diC.sub.1-4 alkylcarbamoyl;R.sup.2 is C.sub.1-4 alkyl;R.sup.3 and R.sup.4 are independently hydrogen or C.sub.1-4 alkyl;R.sup.5 is hydrogen, C.sub.1-2 alkyl, C.sub.1-5 alkanoyl or C.sub.1-4 alkoxycarbonyl, the group R.sup.5 being attached at the 1- or 2-position of the pyrazole ring;X is C.sub.1-7 alkylene or a group of the formula:--(CH.sub.2).sub.m --Y--(CH.sub.2).sub.n --whereinm is 2 or 3,n is an integer of 0 to 3,and Y is oxygen, sulfur, imino or N-C.sub.

Abstract: Novel compounds, e.g., N-(5,7-dimethyl-1,2,4-triazolo [1,5-a]pyrimidin-2-yl)-2-thiophene sulfonamide and their compositions and use in the control of weeds.

Abstract: The invention relates to 2,6-piperazinedione derivatives of general formula I ##STR1## in which: A and B each denote a methylene radical or a carbonyl radical with the proviso, however, that A and B never simultaneously denote the same radical,R.sub.1 denotes a diphenylmethyl radical optionally substituted on the benzene rings with a halogen atom, a cyclohexyl radical, a pyridylmethyl group, or a benzyl radical optionally substituted with a halogen atom or with an alkoxy radical containing from 1 to 4 carbon atoms,R.sub.2 denotes a pyrimidinyl radical or a phenyl radical optionally substituted with a halogen atom, with an alkyl radical having from 1 to 4 carbon atoms, with a trifluoromethyl radical or with an alkoxy radical containing from 1 to 4 carbon atoms,n is an integer from 2 to 4,and their addition salts with a pharmaceutically acceptable inorganic or organic acid.

Abstract: There is described a product which is a highly pure substantially amorphous form of cefuroxime axetil (cefuroxime 1-acetoxyethyl ester) which is stable, which has increased absorption via the gastro-intestinal tract and has a correspondingly high level of bioavailability on oral or rectal administration.Methods of preparing the product are also described which involve the recovery of the product from a solution thereof. A preferred method is the use of spray drying techniques, though roller drying, solvent precipitation or freeze-drying are also described.Also disclosed are pharmaceutical compositions containing the product and methods for its use in medicine.

Abstract: 2,4-Diaminopteridine derivatives and the pharmaceutically acceptable salts thereof having potent anticancer activity are disclosed. The derivatives possess the structural formula: ##STR1## wherein Y is NH.sub.2, OH or SH, R is ##STR2## and X is ##STR3## in which R' is H or CH.sub.3 or ##STR4## in which R and R' are as previously defined, provided when Y is NH.sub.2, R' must be CH.sub.3 and when Y is OH, R' must be OH.

Abstract: Disclosed are novel oxazolidinedione derivatives expressed by the following formula: ##STR1## (R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 being defined in the specification), a method of producing the derivatives and herbicides containing the derivatives as an active ingredient.These novel derivatives exhibit excellent weed-killing activity for harmful weeds and low phytotoxicity for crops.

Abstract: Novel substituted triazolo[1,5-a]pyrimidine-2-sulfonamides, e.g., 5,7-dimethyl-N-(2,6-dichlorophenyl)-1,2,4-triazolo[1,5-a]pyrimidine-2-sulf onamide and their agriculturally acceptable salts are prepared. These compounds and compositions containing them are useful for the control of unwanted vegetation. Novel substituted triazolo[1,5-a]pyrimidine-2-sulfonyl chlorides and substituted anilines and their use as intermediates are also described.