Patents Examined by Matthew Schall
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Patent number: 10016534Abstract: The present invention relates to protein biocoacervates and biomaterials vessel graft systems used in cardiovascular applications and other medical applications, the components utilized in the vessel graft systems and the methods of making and using such systems. More specifically the present invention relates to protein biocoacervates and biomaterials vessel graft systems used in various medical applications and/or the devices used in such vessel graft systems including, but not limited to, vessel grafts as drug delivery devices for the controlled release of pharmacologically active agents, tubular grafts, vascular grafts, protein biomaterial sutures and biomeshes, protein biomaterial adhesives and glues, and other biocompatible biocoacervate or biomaterial devices used in the vessel graft systems of the present invention.Type: GrantFiled: November 17, 2009Date of Patent: July 10, 2018Assignee: Gel-Del Technologies, Inc.Inventor: David B. Masters
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Patent number: 10010410Abstract: A prosthetic heart valve is provided with a cuff having features which promote sealing with the native tissues even where the native tissues are irregular. The cuff may include a portion adapted to bear on the LVOT when the valve is implanted in a native aortic valve. The valve may include elements for biasing the cuff outwardly with respect to the stent body when the stent body is in an expanded condition. The cuff may have portions of different thickness distributed around the circumference of the valve in a pattern matching the shape of the opening defined by the native tissue. All or part of the cuff may be movable relative to the stent during implantation.Type: GrantFiled: July 10, 2013Date of Patent: July 3, 2018Assignee: St. Jude Medical, LLCInventors: Peter Nicholas Braido, Paul Edward Ashworth, Julia Ann Schraut
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Patent number: 10005269Abstract: A medical appliance or prosthesis may comprise one or more layers of rotational spun nanofibers, including rotational spun polymers. The rotational spun material may comprise layers including layers of polytetrafluoroethylene (PTFE). Rotational spun nanofiber mats of certain porosities may permit tissue ingrowth into or attachment to the prosthesis. Additionally, one or more cuffs may be configured to allow tissue ingrowth to anchor the prosthesis.Type: GrantFiled: November 15, 2013Date of Patent: June 26, 2018Assignee: Merit Medical Systems, Inc.Inventors: John William Hall, Zeke Eller, Robert S. Kellar, Rachel Lynn Simmons, Bart Dolmatch, Wayne Mower, Robert J. Radford
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Patent number: 9993331Abstract: A stent for use in a medical procedure having opposing sets of curved apices, where the curved section of one set of apices has a radius of curvature that is greater than the curved section of the other set of apices. One or more such stents may be attached to a graft material for use in endovascular treatment of, for example, aneurysm, thoracic dissection, or other body vessel condition.Type: GrantFiled: May 24, 2017Date of Patent: June 12, 2018Assignee: COOK MEDICAL TECHNOLOGIES LLCInventors: David Brocker, William K. Dierking, Alan R. Leewood, Timothy A. M. Chuter, Blayne A. Roeder, Steven J. Charlebois
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Patent number: 9993588Abstract: There is disclosed apparatus and methods for providing a reserve power source for a ventricular assist device. In an embodiment, the apparatus includes a primary power source for powering the device, and a controller housing having a reserve battery for powering the device when the primary power source provides inadequate power, and the controller housing configured for use externally of the patient with a percutaneous cable to the device. In another embodiment, a method includes powering the device with a primary power source, monitoring power provided to the device, powering the device when the power is monitored as inadequate to the device with a reserve power source disposed within a controller housing, the device disposed subcutaneously within a patient, the controller housing disposed externally of the patient, and the device and the controller housing connected by a percutaneous cable. Other embodiments are also disclosed.Type: GrantFiled: June 6, 2008Date of Patent: June 12, 2018Assignee: WorldHeart, Inc.Inventors: Jim Lee, James Malmstrom, James Long
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Patent number: 9987833Abstract: A medical appliance or prosthesis may comprise one or more layers of rotational spun nanofibers, including rotational spun polymers. The rotational spun material may comprise layers including layers of polytetrafluoroethylene (PTFE). Rotational spun nanofiber mats of certain porosities may permit tissue ingrowth into or attachment to the prosthesis. Additionally, one or more cuffs may be configured to allow tissue ingrowth to anchor the prosthesis.Type: GrantFiled: January 15, 2013Date of Patent: June 5, 2018Assignee: MERIT MEDICAL SYSTEMS, INC.Inventors: John William Hall, Zeke Eller, Robert S. Kellar, Rachel Lynn Simmons, Bart Dolmatch, Wayne Mower, Robert J. Radford
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Patent number: 9987399Abstract: The present invention relates to the field of non-biodegradable stents, and therein to non-biodegradable stents coated with at least one layer of a biodegradable polymer which maintains mechanical integrity of the coating both in storage and upon balloon expansion and which can optionally release drugs. The at least one polymer layer comprises a biodegradable polymer and a plasticizer. The present invention also relates to a manufacturing method of such a non-biodegradable stent.Type: GrantFiled: October 30, 2008Date of Patent: June 5, 2018Assignee: Nanyang Technological UniversityInventors: Subramanian Venkatraman, Yin Chiang Boey, Laxmikant Khanolkar
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Patent number: 9980818Abstract: An exemplary two-stage prosthetic heart valve system has a radially expandable base stent implanted within a native valve annulus. The base stent desirably has three position markers projecting in the axial direction from the outflow end of the base stent to assist in aligning the stent with respect to the commissures of the native valve. The two-stage heart valve system also has a valve component that is delivered to and mounted within the base stent in a separate or sequential operation after the base stent has been anchored within the annulus. The valve component in certain embodiments comprises a hybrid valve component that includes a conventional, non-expandable surgical valve that is modified to include an expandable coupling stent that can be expanded to engage the inner surface of the base stent, thereby anchoring the valve component to the base stent.Type: GrantFiled: March 2, 2010Date of Patent: May 29, 2018Assignee: Edwards Lifesciences CorporationInventors: Mark Chau, Qinggang Zeng
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Patent number: 9980815Abstract: A device for regulating blood pressure between a patient's left atrium and right atrium comprises an hourglass-shaped stent comprising a neck region and first and second flared end regions, the neck region disposed between the first and second end regions and configured to engage the fossa ovalis of the patient's atrial septum; and a one-way tissue valve coupled to the first flared end region and configured to shunt blood from the left atrium to the right atrium when blood pressure in the left atrium exceeds blood pressure in the right atrium. The inventive devices may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits. The inventive devices may be used, for example, to treat subjects having heart failure, pulmonary congestion, or myocardial infarction, among other pathologies.Type: GrantFiled: May 14, 2015Date of Patent: May 29, 2018Assignee: V-Wave Ltd.Inventors: Yaacov Nitzan, Menashe Yacoby
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Patent number: 9981072Abstract: Provided herein is a coated coronary stent, comprising: a. stent; b. a plurality of layers deposited on said stent to form said coronary stent; wherein at least one of said layers comprises a bioabsorbable polymer and at least one of said layers comprises one or more active agents; wherein at least part of the active agent is in crystalline form.Type: GrantFiled: March 31, 2010Date of Patent: May 29, 2018Assignee: Micell Technologies, Inc.Inventors: Douglas Taylor, James B. McClain
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Patent number: 9974653Abstract: Apparatus is provided, including an intracardiac annuloplasty structure configured for placement on an annulus of a heart valve, a first rotatable ring coupled to the annuloplasty structure and a second rotatable ring coupled to the annuloplasty structure. The first and second rotatable rings are arranged such that the first rotatable ring is rotatable to contract the annuloplasty structure while the second rotatable ring remains stationary, and the second rotatable ring is rotatable to contract the annuloplasty structure while the first rotatable ring remains stationary. Other embodiments are also described.Type: GrantFiled: August 29, 2016Date of Patent: May 22, 2018Assignee: Valtech Cardio, Ltd.Inventors: Amir Gross, Iftah Beinart, Eran Miller, Oz Cabiri, Eliahu Eliachar, Nir Lilach, Ram Grossfeld, Dmitry Golom, Gideon Meyer-Brodnitz, Arnon Mousaiuf
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Patent number: 9974656Abstract: A femoral neck prosthesis (10) with a cross-section defined by a perimeter comprising: first and second arcuate portions (12, 14) disposed opposite one another; and first and second substantially straight portions (16, 18) disposed opposite one another and in between the first and second arcuate portions, wherein the first and second straight portions are non-parallel with respect to one another.Type: GrantFiled: October 28, 2009Date of Patent: May 22, 2018Assignee: Biomet UK LimitedInventors: Christos Pappas, Robert John Andrew Bigsby, Gordon William Blunn, Poul T. Nielsen
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Patent number: 9968470Abstract: A stent for bifurcation, including two cylindrical parts: a distal part (1.1) of smaller diameter and a proximal part (1.2) of greater diameter, connected by two arranged as opposite longitudinal connectors (1.3) having length (L1) of 0.5 to 8 mm and forming a cell of the stent having an enlarged surface area (1.4), the connectors having a curvilinear shape, in particular a sinusoidal shape. A method of introducing the stent and a system for intravascular implantation are disclosed.Type: GrantFiled: June 27, 2014Date of Patent: May 15, 2018Assignee: BALTON SP. Z O.O.Inventors: Emil Plowiecki, Leszek Hurkala
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Patent number: 9943400Abstract: An endoluminal prosthesis comprises a prosthetic trunk having a trunk lumen and a trunk wall, a first prosthetic branch having a first branch lumen and a branch wall, and a second prosthetic branch having a second branch lumen. The first branch lumen and the second branch lumen are both in fluid communication with the trunk lumen through the trunk wall and the second branch lumen is in fluid communication with the first branch lumen through the branch wall. Additional devices, systems, and methods are disclosed.Type: GrantFiled: September 4, 2015Date of Patent: April 17, 2018Assignee: The Cleveland Clinic FoundationInventors: Roy K. Greenberg, Karl J. West, Davorin K. Skender, James C. Foster
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Patent number: 9918835Abstract: A medical device for treating a heart valve insufficiency, with an endoprosthesis which can be introduced into a patient's body and expanded to secure a heart valve prosthesis in the patient's aorta. In an embodiment, the endoprosthesis has a plurality of positioning arches configured to be positioned with respect to a patient's aorta and a plurality of retaining arches to support a heart valve prosthesis. The endoprosthesis includes a first collapsed mode during the process of introducing it into the patient's body and a second expanded mode when it is implanted.Type: GrantFiled: April 14, 2016Date of Patent: March 20, 2018Assignee: JenaValve Technology, Inc.Inventors: Volker Guyenot, Thomas Peschel, Christoph Damm, Hans-Reiner Figulla, Markus Ferrari, Johannes Jung
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Patent number: 9913704Abstract: Various embodiments of craniofacial implants, surgical instruments, and techniques are described to provide improved surgical results.Type: GrantFiled: December 23, 2008Date of Patent: March 13, 2018Inventor: Michael J. Yaremchuk
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Patent number: 9908143Abstract: Tubular casting processes, such as dip-coating, may be used to form substrates from polymeric solutions which may be used to fabricate implantable devices such as stents. The polymeric substrates may have multiple layers which retain the inherent properties of their starting materials and which are sufficiently ductile to prevent brittle fracture. Parameters such as the number of times the mandrel is immersed, the duration of time of each immersion within the solution, as well as the delay time between each immersion or the drying or curing time between dips and withdrawal rates of the mandrel from the solution may each be controlled to result in the desired mechanical characteristics. Additional post-processing may also be utilized to further increase strength of the substrate or to alter its shape.Type: GrantFiled: May 21, 2012Date of Patent: March 6, 2018Assignee: Amaranth Medical Pte.Inventors: Kamal Ramzipoor, Alfred N. K. Chia, Liwei Wang, Chang Y. Lee
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Patent number: 9901443Abstract: Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an anchoring member having a first portion configured to engage with tissue on or near the annulus of the native heart valve and to deform in a non-circular shape to conform to the tissue. The device can also include a valve support coupled to a second portion of the anchoring member, configured to support a prosthetic valve and having a cross-sectional shape. In some embodiments, the first portion of the anchoring member is mechanically isolated from the valve support such that the cross-sectional shape of the valve support remains sufficiently stable that the prosthetic valve remains competent when the anchoring member is deformed in the non-circular shape.Type: GrantFiled: August 7, 2015Date of Patent: February 27, 2018Assignee: Twelve, Inc.Inventors: John Morriss, Hanson Gifford, III, James I. Fann, Jean-Pierre Dueri, Matt McLean, Darin Gittings, Michael Luna, Mark Deem, Douglas Sutton, Jeffry J. Grainger
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Patent number: 9901446Abstract: Disclosed replacement heart valves can be designed to be delivered to a native valve site while crimped on a delivery catheter. The crimped profile of the replacement valve can be minimized by, for example, separating a frame or stent structure from a leaflet structure, along the axial direction. Disclosed replacement valves can be transitioned from a delivery configuration, in which the crimped profile can be minimized, to an operating configuration. The replacement valve can be fully assembled in both the delivery and operating configurations. In some embodiments, the leaflets can be positioned outside of the stent in the delivery configuration, and positioned inside of the stent lumen in the operating configuration. Disclosed replacement valves can include a flexible sleeve coupling the leaflets to the stent and facilitating the transition to the operating configuration. Methods of implanting said replacement valves are also disclosed.Type: GrantFiled: July 8, 2014Date of Patent: February 27, 2018Assignee: Edwards Lifesciences CorporationInventors: Netanel Benichou, Stanton J. Rowe, Sean Chow
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Patent number: 9901349Abstract: An intra-vascular aneurysm-treatment stent and a method for lowering pressure within an aneurysm bubble in a blood vessel. A stent coil is insertable into a blood vessel, the coil made of a material sufficiently flexible to move around curves, loops, and corners in the blood vessel. The stent coil is positioned in the blood vessel with selected stent coil portions proximate an opening into either a saccular aneurysm or a fusiform aneurysm. Blood in the lumen of the blood vessel flows past the leading edges and both over the outer surfaces, and under the inner surfaces. A portion of the blood inside the aneurysm becomes entrained with the blood flowing over the outer surfaces. At the trailing edges, the converging blood flows create eddies.Type: GrantFiled: May 30, 2017Date of Patent: February 27, 2018Inventor: Joseph Horton