Abstract: A composition with three hormone components is administered to a mammal to cause the suppression or cessation of the menstruation cycle. Alternatively, it can be administered for treatment of tumors of the mammary gland. The composition contains at least a synthetic estrogen, a biogenetic estrogen, and a gestagen. Alternatively, the composition can include hormones which upon ingestion are metabolized to the above-mentioned hormones.

Abstract: Herein is disclosed an oily material composition comprising, as effective components, both a specific alkyl or alkenyl ester of an N-long chain acyl neutral amino acid and a specific sterol ester of an N-long chain acyl neutral amino acid, or further an amphipathic substance in addition to the said two kinds of esters, which composition has both good moisturizing property and good moisture-permeating property, as well as good water-incorporating property and good emulsification stability, and shows a good feel on use (i.e., non-stickiness, good compatibility, no heavy touch and good spreadability), and shows, when incorporated in a cosmetic composition or a dermal external agent composition, an advantage of giving moisturizing property and moisture-permeating property as well as emulsification stability thereto and of giving a good feel on use.

Abstract: A formulation comprising a phosphate salt, particularly sodium tripolyphosphate for cleansing and treating human skin is disclosed. The formulation provides exfoliating properties useful in gently peeling the skin, as well as sequestering properties for removing harmful metals from the skin. The preferred method for the formulations use is also disclosed.

Abstract: A cosmetic or dermatological composition for treating keratinous material, particularly human hair, including a cosmetically or dermatologically acceptable medium containing at least one silicone-grafted polymer with a polysiloxane portion and a portion consisting of a non-silicone organic chain, wherein one of the two portions constitutes the main polymeric chain while the other is grafted onto said main chain, and at least one copolymer with a polysiloxane-polyoxyalkylene linear block as the repetitive units, as well as the uses thereof, are disclosed. Such compositions are particularly suitable for use as rinsable or non-rinsable products for washing and conditioning hair, hair setting or hair styling.

Abstract: A temperature-stable cosmetic composition including a polyamide resin, a solvent for the polyamide resin, and a gelling agent selected from the group consisting of N-acyl amino acid amides, N-acyl amino acid esters, and mixtures thereof, is disclosed. A composition of the invention can be made translucent or transparent, need not require specialized packaging and containers, is not subject to hardening caused by evaporation of volatile alcohols, is temperature-stable over a period of several weeks, and exhibits excellent esthetic and functional properties, including sensory properties, for consumer acceptance.

Abstract: A composition for topical application to the skin, contains an active principle with irritant character in a cosmetically or pharmaceutically acceptable vehicle, in which the vehicle contains more than 5% by weight of peroxidized vegetable oil having a peroxidation level of between 5 and 600 milliequivalents per kg. The presence of the peroxidized oil reduces the irritant character of the principle, particularly capsaicin and retinoic acid.

Abstract: A moisturizing composition comprising a trihydric or more water soluble polyhydric alcohol, lecithin and 3-methyl-1,3-butylene glycol, wherein lecithin: the trihydric or more water soluble polyhydric alcohol+3-methyl-1,3-butylene glycol=1:1,000 to 1:1 (weight ratio) and the trihydric or more water soluble polyhydric alcohol:3-methyl-1,3-butylene glycol=1:10 to 20:1 (weight ratio), various bases containing the moisturizing composition, and a cosmetic or external preparation containing the moisturizing composition. The moisturizing composition, bases, and cosmetic and external preparation are excellent in moisturizing properties, and have good stability.

Abstract: The invention provides novel and advantageous delivery devices for compositions of cetyl myristoleate. The delivery devices include transdermal delivery devices, suppositories, enteric coatings, and microencapsulation. Further provided are methods of treating diseases using the disclosed delivery devices. Diseases that can be treated with the devices include, but are not limited to, diseases associated with the inflammation of tissues, diseases associated with inflammatory conditions affecting joints, and autoimmune diseases.

Abstract: A medical solution tubing useful in combination with medical solution packages and pouches includes an outer layer of polypropylene, ethylene propylene copolymer, or modified ethylene propylene copolymer; an intermediate layer comprising a polymeric elastomer, a blend of a low melt index EVA and a high melt index EVA, EnBA, or blends thereof, or a blend of an EVA-based polymeric adhesive and an elastomeric polyester; and an inner layer comprising EVA, a blend of a low melt index EVA and a high melt index EVA, EMA, EnBA, or blends thereof, or PVC.

Abstract: A coextruded packaging film has an outer and intermediate layer of fully hydrolyzed polyvinyl alcohol, partially hydrolyzed polyvinyl alcohol, or polyethylene oxide; and an inner layer comprising acid/acrylate copolymer, styrene maleic anhydride copolymer, ethylene acrylic acid copolymer, ionomer, cellulose, hydroxy propyl cellulose, polyether block amide copolymer, polyhydroxy butyric acid, polyhydroxy valeric acid, polyethylene oxide, polyester, copolyester, polyethyloxazoline, polyurethane, partially metal salt neutralized acid/acrylate copolymer, and a blend of acid/acrylate copolymer and ionomer. Fillers such as salt can optionally be added to one or more of the polymeric materials, prior to or during coextrusion of the film, to improve the processability of the film or to add a pigment to the film.

Abstract: Cosmetic skin care compositions containing cumic alcohol. The inventive compositions improve transglutaminase-1 and ceramide expression in skin cells, and enhance the cell uptake of glucose and ascorbic acid.

Abstract: A viscous gel for delivering minor effective homeopathic amount of zinc or another metal to the nasal membrane.

Abstract: A composition in the form of an anhydrous emulsion having as a dispersed phase ascorbic acid dissolved in a nonaqueous polar organic solvent, and as the continous phase a nonaqueous nonpolar organic solvent, as well as a method for dissolving ascorbic acid.

Abstract: A non-occlusive medication patch to be applied to the skin includes a porous self-supporting backing layer to give the patch the required integrity and strength by acting as a supporting framework for other components, and a flexible hydrophilic pressure-sensitive adhesive reservoir comprising a natural or synthetic polymer for the sustained release of medication to be absorbed topically through the skin into the body of a patient. The reservoir has two portions: first, an external coating layer with an exposed lower skin-contacting surface that forms a pressure-sensitive bond with the skin, and second, an upper internal portion which infiltrates the porous backing and becomes solidified therein after being applied so that the reservoir and the backing are unified, enabling the backing itself to act as a storage location for the medication-containing reservoir.

Abstract: Dispersibility of a respirable powder, administrable by inhalation, is increased by including a pharmaceutically acceptable water-soluble polypeptide.

Abstract: White or colored pigments which do not suffer from color tone or hiding performances thereof even when the surface is moistened with water or oil, without spoiling coloring performance or hiding performance of the pigments themselves. These pigments are surface-coated with an inorganic compound having the refractive index of 1.8 or below. The inorganic compound is preferably silicon oxide, and the pigments are preferably inorganic pigments comprising titanium oxide, zinc oxide, or iron oxide. The cosmetics of the invention are blended the pigments therein.

Abstract: A transdermal absorption preparation containing &agr;-form crystals of indomethacin in a vehicle. The present invention aims to provide an indomethacin-containing transdermal absorption preparation increased in the percutaneous absorption of indomethacin from the preparation, and improved in the stability of indomethacin in the preparation.

Abstract: The present invention relates to the use of at least two compounds chosen from components having an a) anti-radical, b) anti-inflammatory and c) anti-allergic activity for the preparation of a composition exhibiting at least two of the a), b) and c) activities intended for the treatment of sensitive and/or allergic skin. It also relates to a process for the preparation of such compositions and to the compositions thus obtained.

Abstract: The present invention relates to compositions and methods for treating cell damage caused by reactive oxygen species in relation to a variety of skin disorders. More specifically, the present invention relates to the treatment skin disorders through the topical delivery of reactive oxygen metabolite production or release inhibiting compounds.

Abstract: The invention relates to a method of treating Attention Deficit Disorder (ADD) and Attention Deficit/Hyperactivity Disorder (ADHD) and compositions for topical application of methylphenidate comprising methylphenidate in a flexible, finite system wherein the methylphenidate is present in an amount sufficient to achieve substantially zero order kinetics for delivery to the skin or mucosa of a patient in need thereof over a period of time at least 10 hours.