Abstract: Disclosed are a composition containing a transition metal, as well as a method of treatment of bacterial, or of fungal diseases using such composition. The composition functions as novel bactericides and antifungal agents. The transition metal may be in either soluble or insoluble form.
Abstract: An oral film in an individual unit dose for delivery of one or more actives is disclosed herein, the film having a precisely calculated and controlled active dissolution profile. A wide variety of actives may be used, including, for example, clobazam, diazepam, or riluzole. Also disclosed are methods of treating a variety of diseases and conditions, for example, epilepsy and seizures, by administering the oral film disclosed herein.
Type:
Grant
Filed:
September 5, 2019
Date of Patent:
January 3, 2023
Assignee:
Aquestive Therapeutics, Inc.
Inventors:
Alexander Mark Schobel, Stephen Wargacki, Vincent J. Buono, Susan Shumard, Christopher James Santee
Abstract: The invention relates to a sprayable liquid solution for the transdermal delivery of testosterone comprising testosterone, a penetration enhancer, and a film forming excipient, and to methods of treatment using this composition.
Abstract: The compound N-(4-{[4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl]oxy}butyl)octadecanamide is a useful drug compound for enhancing immune response and can be used, for example, as a coronavirus vaccine adjuvant.
Abstract: The present invention relates to compositions for removing nail polish that include a C2-C3 monoalcohol, at least about 15% glycerin, and at least about 20% by weight of a C2-C4 alkyl acetate, and combinations thereof. The compositions include less water than glycerin. Methods of using these compositions to remove nail polish and moisturize the hands are also provided.
Abstract: The present disclosure relates to topical sunscreen formulations comprising a semifluorinated alkane and a metal oxide selected from titanium dioxide, zinc oxide or mixtures thereof.
Type:
Grant
Filed:
September 20, 2019
Date of Patent:
November 29, 2022
Assignee:
DERMALIQ THERAPEUTICS, INC.
Inventors:
Frank Löscher, Ralf Grillenberger, Chiara Silvana Leo, Markus Beier
Abstract: An oral care mouth rinse composition containing at least one ionic tin source and polyvinylpyrrolidone wherein the polyvinylpyrrolidone is present in an amount of from 1.5 to 4 weight % based on the total weight of the oral care mouth rinse composition is provided.
Type:
Grant
Filed:
December 18, 2015
Date of Patent:
November 22, 2022
Assignee:
Colgate-Palmolive Company
Inventors:
Sylvia Hess, Ruth Hinrichs, Stephanie Jakumeit, Turan Matur, Andre Brunella, Peter Reiff
Abstract: A single-use, oral dosage forms (e.g., fast-dissolving strips) is disclosed, as well as methods of using such oral dosage forms to sweeten edible compositions. Methods of manufacturing single-use, oral dosage forms are also provided.
Type:
Grant
Filed:
June 27, 2018
Date of Patent:
November 8, 2022
Assignee:
The Coca-Cola Company
Inventors:
Youlung Chen, Xiaoliang Tan, Juvenal Higiro, Indra Prakash, Robert M. Kriegel, Yu Shi, Haiyu Ren
Abstract: Provided herein are methods for treating pulmonary hypertension. The methods include administering to a subject in need thereof an effective amount of a vasodilator, wherein the vasodilator is administered to the subject via inhalation pro re nata using a portable inhaler. In some embodiments, the vasodilator is a PDE5 inhibitor. Pharmaceutical compositions for pro re nata administration of vasodilators are also described.
Type:
Grant
Filed:
November 23, 2021
Date of Patent:
November 8, 2022
Assignee:
Respira Therapeutics, Inc.
Inventors:
Jeffry Weers, Alain Romero, Hugh Smyth, Robert Curtis, Adaani Frost, Zhen Xu, Revati Shreeniwas, Martin Donovan
Abstract: Provided herein are methods for treating pulmonary hypertension. The methods include administering to a subject in need thereof an effective amount of a vasodilator, wherein the vasodilator is administered to the subject via inhalation pro re nata using a portable inhaler. In some embodiments, the vasodilator is a PDE5 inhibitor. Pharmaceutical compositions for pro re nata administration of vasodilators are also described.
Type:
Grant
Filed:
January 11, 2021
Date of Patent:
November 8, 2022
Assignee:
Respira Therapeutics, Inc.
Inventors:
Jeffry Weers, Alain Romero, Hugh Smyth, Robert Curtis, Adaani Frost, Zhen Xu, Revati Shreeniwas, Martin Donovan
Abstract: Photostabilizing compounds are provided. In particular, the photostabilizing compounds may be heterocyclic or homocyclic. Topical compositions comprising these compounds are also provided. In particular, these topical compositions may further comprise photoactive compounds. Methods for stabilizing photoactive compounds are also provided. These methods comprise mixing the photoactive compounds with photostabilizing compounds.
Abstract: The present invention relates to a solid pharmaceutical preparation of 3-Fluoro-4-[7-methoxy-3-methyl-8-(1-methyl-1H-pyrazol-4-yl)-2-oxo-2,3-dihydro-imidazo[4,5-c]quinolin-1-yl]-benzonitrile, a method of making same, and medical uses thereof.
Type:
Grant
Filed:
August 8, 2018
Date of Patent:
October 25, 2022
Assignee:
Merck Patent GmbH
Inventors:
Simon Geissler, Stefan Schiller, Meike Harms, Holger Kubas, Markus Weigandt, Michael Lange
Abstract: The inventive subject matter is directed to compositions and methods for sterile and storage stable low-dose atropine formulations with improved stability. Most preferably, the compositions presented herein are substantially preservative free and exhibit less than 0.35% tropic acid from degradation of atropine. Advantageously, contemplated formulations are also substantially free of preservatives.
Type:
Grant
Filed:
July 20, 2020
Date of Patent:
October 11, 2022
Assignee:
VYLUMA INC.
Inventors:
Navneet Puri, Prem Sagar Akasapu, Irfan A. Mohammed, Kumaresh Soppimath, Iouri V. Ilitchev
Abstract: The invention relates to a W/O emulsion for impregnating nonwoven containing 10-60% by weight of vegetable oil, 0.1-25% by weight of emollients, 10 to 50% by weight of water, a lipophilic emulsifier, an inorganic salt as well as at least one antioxidant, wherein the emulsifier is polyglyceryl-4-diisostearate/polyhydroxystearate/sebacate and the viscosity of the emulsion is 250-600 mPa·s, determined using a DIN measuring system 33 according to ISO 53019 at a temperature of 293.15 K and at a rotation speed of 500 r/min.
Abstract: The invention relates to the non-therapeutic use of a composition comprising at least one 1,4:3,6 dianhydrohexitol for moisturising the skin, as well as to a preparation for topical use comprising at least one 1,4:3,6 dianhydrohexitol as a moisturising agent.
Abstract: A cosmetic composition to prevent and/or ameliorate skin aging and applications thereof are provided in the present disclosure and the cosmetic composition comprises cyclic phosphatidic acid and citrus flavonoids which is hesperidin and/or hesperetin wherein the preventing and/or ameliorating skin aging include, without limitation, promoting moisture retention of stratum corneum, promoting skin elasticity, increasing presence or elasticity of collagens and elastins in fibroblasts, increasing transfers of fibroblasts, promoting anti-oxidation, increasing generation of hyaluronic acid, alleviating wrinkles and skin textures, moderating melanin, reducing skin oil and preventing transepidermal water losses.
Abstract: The present invention relates to a detoxified powder composition comprising a zinc-bearing compound selected from the group consisting of zinc carbonate, zinc hydroxide, zinc oxide, zinc sulphate and mixtures thereof, and at least one detoxification agent containing at least one oxide based on a cation, selected from the group consisting of calcium, barium, magnesium, strontium and beryllium.
Type:
Grant
Filed:
December 14, 2017
Date of Patent:
September 6, 2022
Assignee:
SOCIETE INDUSTRIELLE LIEGEOISE DES OXYDES SA
Abstract: A sunscreen composition is provided. The sunscreen composition includes non-nano zinc oxide, a carrier, and a component selected from the group consisting of a humectant, a thickener, a dispersing agent, an emulsifier, an emollient, a preservative, an antioxidant, an odorant, and combinations thereof. The sunscreen composition complies with the natural product standard governed by Cosmetics Organic and Natural Standard (non-profit) (“COSMOS-standard AISBL”).
Abstract: A fibrous structure with a plurality of fibrous elements. The fibrous elements contain a polymeric structurant; a fatty material with a melting point above 25° C.; a cationic surfactant, which can be selected from the group consisting of a mono-long alkyl amine, a tertiary amine, and combinations thereof; and an oil soluble acid. The oil soluble acid can be selected from the group consisting of salicylic acid, lactic acid, acetic acid, malic acid, succinic acid, sorbic acid, 2,4-dihydroxybenzoic acid, maleic acid, and combinations thereof.
Type:
Grant
Filed:
July 1, 2020
Date of Patent:
August 23, 2022
Assignee:
The Procter & Gamble Company
Inventors:
Jennifer Elaine Hilvert, Mark William Hamersky, Emily Lao Hickey
Abstract: The present disclosure provides compositions of rose oil, cannabidiol, and humectants and methods of using said compositions. The present disclosure also products containing the aforementioned products, including a face mask, a serum, a lotion, and an eye cream.
Type:
Grant
Filed:
November 19, 2020
Date of Patent:
August 23, 2022
Assignee:
JLABS Beauty LLC
Inventors:
Justine Mullen, Anne Schlesselman Buthion