Patents Examined by Nghi V Nguyen
  • Patent number: 11459535
    Abstract: In one embodiment, an algae cultivation system includes a basin that contains a liquid and a photobioreactor at least partially immersed in the liquid of the basin, the photobioreactor comprising a closed container including multiple panels that together define an interior space in which algae can be cultivated, at least one of the panels being transparent, the photobioreactor further comprising an inflatable float associated with the container that can be filled with a gas to change one or both of the position and orientation of the container within the liquid.
    Type: Grant
    Filed: November 14, 2016
    Date of Patent: October 4, 2022
    Assignee: University of South Florida
    Inventors: Daniel H. Yeh, Ivy Lea Cormier Drexler, Melanie Pickett, David Fulcher
  • Patent number: 11446316
    Abstract: Disclosed are nutritional compositions including galactooligosaccharides that can be administered to individuals including preterm infants, infants, toddlers, children, and adults for preventing injury and/or improving the healing of the gastrointestinal tract. Additional suitable methods of using the nutritional compositions including the galactooligosaccharides are also disclosed.
    Type: Grant
    Filed: July 19, 2012
    Date of Patent: September 20, 2022
    Assignee: ABBOTT LABORATORIES
    Inventors: Steven R. Davis, Jomay Chow
  • Patent number: 11439143
    Abstract: A temperature sensor for monitoring an organ or tissue is configured to measure a temperature inside of a container configured to contain the organ or tissue. The temperature sensor is disposed exterior to the organ container and the temperature sensor is a non-contact temperature sensor. The temperature sensor may be part of an apparatus for perfusing, transporting, and/or storing an organ or tissue. A coolant container may have an aperture through which the temperature sensor measures a temperature of at least one of the organ or tissue or a perfusate fluid surrounding the organ or tissue. The temperature sensor is preferably an infrared temperature sensor. Multiple temperature sensors may be provided that measure the temperature organ or tissue or perfusate fluid surrounding the organ or tissue, for example in case one of the temperature sensors fails.
    Type: Grant
    Filed: July 10, 2012
    Date of Patent: September 13, 2022
    Assignee: LIFELINE SCIENTIFIC, INC.
    Inventors: David Kravitz, Christopher P. Steinman, David Pettinato, Richard K. Buck, John Stark, Robert J. Allen
  • Patent number: 11414682
    Abstract: A method for microbial fermentation of botanicals includes steps of: fermenting with wall-breaking fungi, and then fermenting with probiotics. The wall-breaking fungi are wood-grown fungi and/or Cordyceps. The method can effectively destroy the cell wall of the botanical, promote release of effective ingredients of the botanical and improve utilization rate of the botanical. In addition, due to fermenting with the wall-breaking fungi, the botanical medicine also contains the active ingredients of the wall-breaking fungi. Thereby the efficacy of the botanical is increased.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: August 16, 2022
    Assignee: CHANGSHA OMICS BIO-TECH CO. LTD
    Inventors: Dongbo Liu, Lei Wang, Xincong Kang, Si Zhang, Xihu Lai
  • Patent number: 11383015
    Abstract: A method of collecting mononuclear cells includes separating plasma from cellular components of whole blood. The cellular components, which include mononuclear cells and red blood cells, are combined with plasma replacement fluid to form a first mixture. The mononuclear cells of the first mixture are separated from the red blood cells of the first mixture, which may be followed by extracorporeal photopheresis being performed on the mononuclear cells.
    Type: Grant
    Filed: December 26, 2016
    Date of Patent: July 12, 2022
    Assignee: Fenwal, Inc.
    Inventors: Katherine N. Radwanski, Lan T. Nguyen, Jonathan W. Prendergast
  • Patent number: 11382936
    Abstract: The invention provides compositions comprising bacterial strains for treating and preventing autoimmune and inflammatory disorders of the central nervous system.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: July 12, 2022
    Assignee: 4D Pharma Research Limited
    Inventors: Helene Savignac, Imke Elisabeth Mulder, Alexander James Stevenson
  • Patent number: 11364285
    Abstract: Methods and compositions for controlling termite populations by leveraging newly discovered mechanisms for symbiont- and host mediated anti-fungal defenses in the termite hind-gut. Such methods may include administering a composition to a termite, the composition formulated to promote protist dysbiosis in the gut of the termite, or silencing specific host or symbiont genes by RNA interference, and exposing the termite to a pathogen, where the composition increases the susceptibility of the termite to the pathogen. Compositions are also provided for the treatment of fungal infections, the composition comprising a medically effective amount of recombinant glycosyl hydrolase family 7 cellulase, as well as methods for utilizing the same.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: June 21, 2022
    Assignee: Purdue Research Foundation
    Inventors: Michael E. Scharf, Brittany F. Peterson
  • Patent number: 11352651
    Abstract: The invention relates to the isolation of polyunsaturated fatty acids (PUFAs) from a lipids containing biomass. The main characteristics of the method are that a suspension of cells containing PUFAs is obtained and the cells are optionally lysed. The suspension is concentrated and then incubated for at least an hour at a controlled temperature while adding a specific range of base equivalents to biomass and maintaining a moderate pH. The isolation of lipid may be performed in the absence of organic solvents and without the addition of salt.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: June 7, 2022
    Assignees: Evonik Operations GmbH, DSM IP Assets B.V.
    Inventors: Michael Diehl, Xiao Daniel Dong, Annika Hartmann, Martin Heining, Michael Benjamin Johnson, Jochen Lebert, Neil Francis Leininger, Kirt Lyvell Matthews, Sr., Mark Edward Nejako, II, Holger Pfeifer, Christian Rabe, Shannon Elizabeth Ethier Resop, Ginger Marie Shank, Vinod Tarwade, David Allen Tinsley
  • Patent number: 11337990
    Abstract: Disclosed are nutritional compositions including human milk oligosaccharides that can be administered to individuals including preterm infants, infants, toddlers, and children for improving gastrointestinal function and tolerance, as well as the growth of beneficial bacteria. Additional suitable methods of using the nutritional compositions including the human milk oligosaccharides are also disclosed.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: May 24, 2022
    Assignee: ABBOTT LABORATORIES
    Inventors: Rachael Buck, JoMay Chow, Steven R. Davis
  • Patent number: 11332769
    Abstract: A method for promoting enzymolysis of lignocellulose by using a pH-responsive lignin amphoteric surfactant and recovery of a cellulase. The method includes: adding lignocellulose to a buffer solution, and then adding a pH-responsive lignin amphoteric surfactant and a cellulase; controlling the pH of the mixed solution to be 4.0-6.2, heating the solution to a temperature of 40° C. to 60° C. and reacting at said temperature for 24-96 h to obtain a saccharified hydrolyzate of lignocellulose; and obtaining an enzymolysed liquid by solid-liquid separation, and then adjusting the pH of the enzymolysed liquid to precipitate the pH-responsive lignin amphoteric surfactant and the cellulase for recycling. The method can effectively improve the enzymolysis efficiency of lignocellulose, recover a certain amount of cellulase, and expand the applications of industrial lignin. The method does not require additional equipment, and is simple to operate and environmentally friendly.
    Type: Grant
    Filed: November 27, 2017
    Date of Patent: May 17, 2022
    Assignee: SOUTH CHINA UNIVERSITY OF TECHNOLOGY
    Inventors: Hongming Lou, Xueqing Qiu, Yuxia Pang, Dongjie Yang, Yong Qian, Jinhao Huang, Conghua Yi, Weifeng Liu, Dafeng Zheng
  • Patent number: 11319612
    Abstract: Present invention describes a biotechnological procedure to remove magnetic sulfur impurities from iron concentrate, wherein includes: to bioleach iron concentrate ores agglomerated in heaps under temperature condition between 5 and 35° C., inoculating the iron concentrate ores with Acidithiobacillus thiooxidans cultures, with an inoculum concentration 104 and 106 cel/g and addition of water supplemented with nitrogen and phosphorous source (0.01 to 0.5 g (NH4)2HPO4/L), without potassium addition, adjusting pH between 1.0 and 9.0, and a feeding rate between 5 and 15 L/h/m2; this procedure allows a removal efficiency above 80% in 21 days, with a maximum iron loss of 3%.
    Type: Grant
    Filed: August 24, 2016
    Date of Patent: May 3, 2022
    Assignee: BIOSIGMA S.A.
    Inventor: Roberto Andres Bobadilla Fazzini
  • Patent number: 11298517
    Abstract: A sprayable polymeric foam hemostat for both compressible and non-compressible (intracavitary) acute wounds is disclosed. The foam comprises hydrophobically-modified polymers, such as hm-chitosan, or other amphiphilic polymers that anchor themselves within the membrane of cells in the vicinity of the wound. By rapidly expanding upon being released from a canister pressurized with liquefied gas propellant, the foam is able to enter injured body cavities and staunch bleeding. The seal created is strong enough to substantially prevent the loss of blood from these cavities. Hydrophobically-modified polymers inherently prevent microbial infections and are suitable for oxygen transfer required during normal wound metabolism. The amphiphilic polymers form solid gel networks with blood cells to create a physical clotting mechanism that prevent loss of blood.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: April 12, 2022
    Assignee: University of Maryland, College Park
    Inventors: Matthew Dowling, Srinivasa R. Raghavan
  • Patent number: 11293035
    Abstract: The invention relates to a process for producing biogas from fibrous substrate by anaerobic fermentation. The process is characterised in that a) the fibrous substrate is fed together with process liquid to a fermenter containing anaerobic microorganisms depending on the TSS content ascertained in this fermenter, b) the fibrous substrate is subjected to wet fermentation in this fermenter to produce biogas c) the output containing fermented fibrous substrate is drawn off from the fermenter and the TSS content in the fermenter is ascertained, d) the TSS content ascertained is compared with a fixed target range and e) depending on the result from d), step a) is repeated with adjusted amounts in order to comply with the target range for the TSS in the fermenter.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: April 5, 2022
    Assignee: VERBIO VEREINIGTE BIOENERGIE AG
    Inventors: Oliver Lüdtke, Michael Schlimbach
  • Patent number: 11260084
    Abstract: The presently disclosed subject matter relates to feed additive formulations for monogastric animal feed. Particularly, the disclosed formulations comprise an isolated xylanase enzyme and a B. licheniformis strain PWD-1. The feed additive formulations may further include B. amyloliquefaciens strain Ba-BPD1. The disclosed formulations are useful for addition to feeds for monogastric animals to synergistically improve the performance of the animals.
    Type: Grant
    Filed: August 19, 2019
    Date of Patent: March 1, 2022
    Assignee: BioResource International, Inc.
    Inventors: Jeng-Jie Wang, Giles Shih
  • Patent number: 11226347
    Abstract: Device for automatically analyzing micro organisms in an aqueous sample using filter cytometry comprising at least one filter holder and processing modules, wherein the filter holder is arranged to contain a filter for receiving the sample, wherein the processing modules comprise sample application means for applying the sample to the filter in the holder and imaging means for imaging the micro organisms on the filter, wherein the device furthermore comprises displacement means for automatically moving the filter holder between the processing modules and wherein each of the modules and the filter holder are arranged to removable connect for interaction.
    Type: Grant
    Filed: October 7, 2008
    Date of Patent: January 18, 2022
    Assignee: Biotrack Holding B.V.
    Inventor: Gijsbert Johan Jansen
  • Patent number: 11224680
    Abstract: A bio-ink composition comprises a plurality of bio-block, in which the bio-blocks can serve as basic building blocks in cell-based bioprinting. The bio-blocks, pharmaceutical compositions comprising the bio-blocks, methods of preparing artificial tissues, tissue progenitors, or multi-dimensional constructs, and methods of preparing the bio-blocks are also provided. The bio-blocks, and the multi-dimensional constructs, artificial tissues, and tissue progenitors comprising the bio-blocks or prepared by the methods described herein are useful for tissue engineering, in vitro research, stem cell differentiation, in vivo research, drug screening, drug discovery, tissue regeneration, and regenerative medicine.
    Type: Grant
    Filed: April 14, 2017
    Date of Patent: January 18, 2022
    Assignee: REVOTEK CO., LTD
    Inventors: Yujian James Kang, Xiao Zuo
  • Patent number: 11197473
    Abstract: Provided are a vitrification stabilizer for animal cell cryopreservation fluid, and an animal cell cryopreservation fluid that exhibits superior vitrification capacity due to containing said vitrification stabilizer for animal cell cryopreservation fluid. The vitrification stabilizer for animal cell cryopreservation fluid contains an amphoteric polymer compound selected from the group consisting of: (a) an amphoteric polymer compound obtained by reacting ?-poly-L-lysine with butyl succinic acid anhydride and performing carboxylation; (b) an amphoteric polymer compound obtained by reacting ?-poly-L-lysine with butyl succinic acid anhydride and succinic acid anhydride, and performing carboxylation; and (c) an amphoteric polymer compound obtained by reacting ?-poly-L-lysine with a compound represented by formula (I) and performing carboxylation.
    Type: Grant
    Filed: July 19, 2016
    Date of Patent: December 14, 2021
    Assignee: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kazuaki Matsumura, Manato Suzuki
  • Patent number: 11191790
    Abstract: Provided are a biologically pure Faecalibacterium butyricigenerans strain AF52-21 deposited under CGMCC Accession No. 1.5206 and a composition including the same and a carrier. A method for treating an inflammation-related disease in a subject in need thereof is also provided. The Faecalibacterium butyricigenerans is useful for treating ulcerative colitis and related disorders.
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: December 7, 2021
    Assignee: BGI SHENZHEN
    Inventors: Yuanqiang Zou, Wenbin Xue, Liang Xiao, Xiaoping Li, Jinghong Yu, Chuan Liu
  • Patent number: 11186851
    Abstract: A system for continuous ethanol recovery in an ethanol plant includes a prefermenter receiving high solids corn slurry mash from the ethanol plant. A yeast source injects live yeast cells into the prefermenter, which converts sugar in the mash to ethanol and provides beer with a concentration of the ethanol as output. A prefermenter stripper is configured for receiving an outflow airstream and stripping ethanol and water from down-flowing beer. A yeast source injects live yeast cells from the ethanol plant into the prefermenter. The prefermenter converts sugar in the mash to ethanol and provides beer with a concentration of the ethanol as prefermenter output. The prefermenter stripper receives an upflowing airstream and strips ethanol and water from downflowing beer and leaves the top of the prefermenter stripper with ethanol-laden exhaust. A beer recirculation cooler cools the stripped beer using cooling tower water from the existing plant as a heat sink.
    Type: Grant
    Filed: April 6, 2020
    Date of Patent: November 30, 2021
    Assignee: LucasE3, L.C.
    Inventor: Scott A. Lucas
  • Patent number: 11154577
    Abstract: This document provides methods and materials for treating a mammal (e.g., a human) having one or more tumors. For example, embolic agents including an amnion tissue preparation (e.g., amnion coated embolic agents) that can be used in arterial embolization to reduce or eliminate blood flow in a blood vessel that supplies a tumor are provided.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: October 26, 2021
    Inventor: Gary M. Petrucci