Patents Examined by P. Kathryn Wright
  • Patent number: 11852646
    Abstract: A sample analysis support apparatus includes a sample region in which a sample is to be disposed, a tip region in which a tip is to be disposed, a first operation unit capable of an operation on the sample using the tip, the tip being attachable to and detachable from the first operation unit, a second operation unit capable of an operation on the sample using the tip, the tip being attachable to and detachable from the second operation unit, a transport unit configured to support each of the first operation unit and the second operation unit moveably between the tip region and the sample region, and a movement controller capable of controlling the transport unit to move each of the first operation unit and the second operation unit between the tip region and the sample region.
    Type: Grant
    Filed: April 22, 2019
    Date of Patent: December 26, 2023
    Assignee: Yokogawa Electric Corporation
    Inventor: Takayuki Kei
  • Patent number: 11852645
    Abstract: A wash system for use in an in vitro diagnostic immunoanalyzer utilizes a bridge having a linear track to move cuvettes from one incubation ring portion to another incubation ring portion. Washing stations along the linear track provide a magnetic field and fluid washing of cuvette contents independent of the size and motion of one or more incubation rings.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: December 26, 2023
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Ayman Ismail, Eric Gerolstein, Brian Bolger
  • Patent number: 11850582
    Abstract: Described are exemplary methods for dispensing liquid from a handheld, powered positive displacement pipette.
    Type: Grant
    Filed: October 26, 2020
    Date of Patent: December 26, 2023
    Assignee: Mettler-Toledo Rainin, LLC
    Inventors: Michael McNaul, Hans Bergmann, Richard Hill
  • Patent number: 11845084
    Abstract: Provided are methods and related devices for preparing a cell and tissue culture, including a hanging drop culture. Microwells are specially loaded with cell mixtures using a removable reservoir and forcing cells into the underlying microwells. The removable reservoir is removed and the cells partitioned into the individual microwells and covered by an immiscible layer of fluid. The microwells and immiscible layer is inverted and the cells in the microwells cultured. The microwells may have shape-controlling elements to control the three-dimensional shape of the culture.
    Type: Grant
    Filed: May 4, 2021
    Date of Patent: December 19, 2023
    Assignees: The Board of Trustees of the University of Illinois, Mayo Foundation for Medical Education and Research
    Inventors: Anurup Ganguli, Rashid Bashir, Panagiotis Z. Anastasiadis, George Vasmatzis
  • Patent number: 11846579
    Abstract: According to at least one aspect, a system configured to count cells in a vessel is provided. The system comprises an imaging system configured to image cells in the vessel and a controller coupled to the imaging system. The controller is configured to control the imaging system to capture a focused image of the cells and estimate a number of cells in the focused image. The controller is configured to control the imaging system to capture a focused image of the cells at least in part by controlling the imaging system to capture a plurality of images of the cells in a plurality of focal planes, determining an area of at least one cell in each of the plurality of images, and selecting one image from the plurality of images as the focused image using the area of the at least one cell in the plurality of images.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: December 19, 2023
    Assignee: Thrive Bioscience, Inc.
    Inventors: Kam Lin Wong, Melanie Scully
  • Patent number: 11833507
    Abstract: A system and method for target material retrieval and processing, the system comprising: an adaptor configured to interface with a capture region of a capture substrate for capturing particles in single-particle format within a set of wells, wherein the adaptor comprises a first region configured to interface with the capture region, a second region, and a cavity extending from the first region to the second region; and a support structure coupled to the adaptor and providing a set of operation modes for movement of the adaptor relative to the capture substrate. The system enables methods for magnetic and/or other force-based methods of retrieval of target material (e.g., derived from single cells).
    Type: Grant
    Filed: February 1, 2022
    Date of Patent: December 5, 2023
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Kalyan Handique, Swati Ranade, Vishal Sharma, Austin Payne, Sam Tuck
  • Patent number: 11835537
    Abstract: There is provided a sample ejection system for ejecting a sample from a flow of fluid, the system comprises: a fluid flow channel for receiving, in use, the flow of fluid; a fluid inlet channel connected to the flow channel and arranged to receive, in use, pressurised fluid; a fluid outlet channel connected to the flow channel at a location downstream in the flow direction of the flow of fluid and comprises an outlet. The system is arranged such that, in use, pressurised fluid is applied to the fluid flow channel via the fluid inlet channel to drive fluid from the region of the fluid flow channel between the fluid inlet and outlet channels through the fluid outlet channel and out of the outlet.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: December 5, 2023
    Assignee: TTP Plc
    Inventors: Richard Janse Van Rensburg, Benjamin James Metcalf
  • Patent number: 11828516
    Abstract: A cryogenic storage system includes a transfer module configured to service one or more cryogenic storage freezers. The transfer module includes a working chamber that maintains a cryogenic environment for the transfer of sample tubes between different sample boxes. One or more freezer ports enable the transfer module to receive a sample box extracted from a respective freezer. An input/output (I/O) port enables external access to samples. A box transport robot operates to transport sample boxes between the freezer ports, the working chamber, and the I/O port. A picker robot operates to transfer sample tubes between sample boxes within the working chamber.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: November 28, 2023
    Assignee: AZENTA US, INC.
    Inventors: Lingchen Sun, Bruce Zandi, Frank Hunt, Jr., Aaron Plaisted, Tiffany Holmes, Matthew Albert, Fang Cui, Yuri Rubenchik, Daniel Lamothe
  • Patent number: 11796550
    Abstract: A sample analyzer includes: a reagent container holder including a reagent container holder body configured to hold a reagent container, and a tilt changing part configured to change a tilt of the reagent container holder body; a reagent dispenser configured to aspirate a reagent contained in the reagent container held in the reagent container holder body; a detector configured to detect a signal for analysis from a measurement specimen containing a sample and the reagent dispensed by the reagent dispenser; and a controller that analyzes the sample on the basis of the signal detected by the detector.
    Type: Grant
    Filed: February 10, 2020
    Date of Patent: October 24, 2023
    Assignee: SYSMEX CORPORATION
    Inventors: Takuya Fujii, Hironori Katsumi, Akio Toyoda
  • Patent number: 11796552
    Abstract: A system for automated processing of a plurality of batches, each batch being derived from one biological sample, the system comprising an enclosure which can be closed and sterilized, each batch of the plurality of batches comprising one or more cell processing container; a plurality of reagent containers for holding reagents within the enclosure; at least one reagent dispenser within the enclosure for dispensing reagents during said automated processing; a quality control system within the enclosure for analyzing at least one characteristic of a batch during said automated processing; a harvester within the enclosure for harvesting batches; a robotic system within the enclosure, configured for transporting cell processing containers, decapping or otherwise opening cell processing containers, pipetting reagents or liquids from cell processing containers, and aspirating liquids from cell processing containers, during said automated processing; a tracker for electronically tracking the plurality of batches aft
    Type: Grant
    Filed: September 17, 2021
    Date of Patent: October 24, 2023
    Assignee: Genesis Technologies Limited
    Inventor: Jan-Eric Ahlfors
  • Patent number: 11772096
    Abstract: A system for processing a biological sample includes a substrate comprising a plurality of wells and a plurality of flow channels. The system further includes a flow control system comprising a manifold having a plurality of ports configured to fluidically couple to the plurality of wells, and one or more containment structures configured to contain carrier fluid and fluidically couple to the ports. The flow control system further includes a cradle configured to removably receive the substrate. The flow control system is configured to transmit pressure differential, via the manifold, to the plurality of wells so as to cause a plurality of sample volumes held by at least some wells of the plurality of wells to flow through respective flow channels and cause the carrier fluid to flow through the flow channels and form a plurality of droplets of the plurality of sample volumes separated by the carrier fluid.
    Type: Grant
    Filed: July 7, 2020
    Date of Patent: October 3, 2023
    Assignee: STOKES BIO LTD.
    Inventors: Mark Davies, Tara Dalton, Kieran Curran
  • Patent number: 11768158
    Abstract: An implement analyzing device that is sized for receiving, more than one fluid retainer cartridge assembly is disclosed. The implement analyzing device includes a support member, a housing, a cartridge receiver, at least one cartridge heater, an Imaging, device and an implement analyzing device integrated circuit. The cartridge receiver is disposed within a cavity in the implement analyzing device and defines at least one cartridge viewing window. At least one cartridge heater disposed within the cavity and connected to the cartridge receiver. The imaging device is disposed within the cavity and arranged opposite the at least one cartridge viewing window. The implement analyzing device integrated circuit is communicatively coupled to the at least one cartridge heater and the imaging device.
    Type: Grant
    Filed: October 7, 2020
    Date of Patent: September 26, 2023
    Assignee: NEOGEN CORPORATION
    Inventors: Frank Eric Klein, Andrew John Wheeler, Andrew John DenHartigh, William Hoerner, Nathaniel Banner, Damon Borich, Andrea Grbavac, Alejandro Silveyra, Michelle Silveyra, Zwckxally Obregon
  • Patent number: 11768214
    Abstract: An automatic analyzer includes: a specimen holding unit configured to hold a specimen container in which a specimen is stored; a dispensed container holding unit configured to hold a plurality of dispensed containers; a dispensing probe configured to separate a predetermined amount of the specimen from the specimen container, and configured to dispense the specimen into the dispensed container; a probe washing device configured to wash a leading end of the dispensing probe in a washing liquid; and a controller configured to control driving of the dispensing probe. The controller includes an arithmetic processing unit configured to calculate a concentration of the specimen in the specimen container. The specimen is subject to dilution with the washing liquid adhered to the leading end of the dispensing probe in the probe washing device. The arithmetic processing unit sets a maximum number of times for dispensing the specimen, based on the concentration.
    Type: Grant
    Filed: September 17, 2020
    Date of Patent: September 26, 2023
    Assignee: JEOL Ltd.
    Inventor: Tsuyoshi Yaita
  • Patent number: 11761972
    Abstract: The objective of the present disclosure is to provide a technique for reducing a quantity of magnetic particles remaining on a reaction vessel wall surface in a cleaning step for reducing, in a stepwise manner, an amount of a magnetic particle solution in the reaction vessel. The automated analysis device according to the present disclosure causes an agitating mechanism to operate in such a way that a magnetic substance remaining on the wall surface of the vessel in the previous cleaning step is captured by a cleaning solution in the next cleaning step.
    Type: Grant
    Filed: January 28, 2019
    Date of Patent: September 19, 2023
    Assignee: Hitachi High-Tech Corporation
    Inventors: Tooru Inaba, Ruochi Hsu, Shinya Matsuoka, Takeshi Yokokawa, Daisuke Ebihara
  • Patent number: 11759785
    Abstract: A receptacle holder for supporting at least one fluid-containing receptacle includes a body and an RFID transponder. The body includes an electrically conductive portion defining a first recess configured to receive at least a first fluid-containing receptacle, and an electrically non-conductive portion attached to the electrically conductive portion. The RFID transponder is disposed on the electrically non-conductive portion of the body, and stores information about the receptacle holder. The receptacle holder can also include the first fluid-containing receptacle received within the first recess.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: September 19, 2023
    Assignee: GEN-PROBE INCORPORATED
    Inventors: Trung Q. Pham, Jerry W. Jeffers, II, David Buse, Steven G. Grubbs
  • Patent number: 11761971
    Abstract: The invention relates to an arrangement for preparing a plurality of samples for an analytical method, comprising a carousel with a solid housing and moveable receiving parts for the sample containers; a control for controlling the receiving parts in the carousel; and a sample receiving device for providing the sample for the analytical method. Said arrangement is characterized in that one or more stations for preparing samples are provided on the carousel, the receiving parts for the sample containers of the carousel can be positioned on said stations. Said arrangement also comprises a centrifuge with pairs of opposite lying receiving parts provided for the sample containers, and said receiving parts are arranged such that they can move on the centrifuge for the sample holder such that a transfer of a sample holder between a receiving part in the carousel and a receiving part in the centrifuge can be carried out. The control takes place by the same control which is also provided for controlling the carousel.
    Type: Grant
    Filed: December 23, 2019
    Date of Patent: September 19, 2023
    Inventor: Joachim Gerstel
  • Patent number: 11754580
    Abstract: A sample measurement method of performing first measurement for a blood coagulation test and second measurement for a test different from the blood coagulation test includes: dispensing a sample for use in the first measurement into a first container from a sample container; dispensing the sample for use in the second measurement into a second container different from the first container from the sample container from which the sample for use in the first measurement has been dispensed; performing the first measurement based on the sample dispensed into the first container; and performing the second measurement based on the sample dispensed into the second container.
    Type: Grant
    Filed: December 26, 2018
    Date of Patent: September 12, 2023
    Assignee: SYSMEX CORPORATION
    Inventors: Shunsuke Ariyoshi, Tsuyoshi Fukuzaki, Masaki Shiba
  • Patent number: 11752496
    Abstract: The present invention discloses a mobile laboratory for use in environment testing, comprising a laboratory casing, lifting hooks are provided at four corners of a top part of an outer wall of the laboratory casing, a supporting frame is provided beneath a bottom of the laboratory casing, an testing room is provided in one side of the laboratory casing and beneficial effects are: by providing lifting hooks, it is convenient to lift and move the mobile laboratory, change orientation as per usage conditions with a transportation vehicle and to build quickly a mobile laboratory for use in the testing site; and the signal transceiver transmits testing data collected by near-infrared spectroscopy, biosensor technology, biochip detection technology, ATP bioluminescence method, immunological analysis method and immunological analysis method by QR code tags, RFID tags, cameras, temperature sensors, sound sensors, vibration sensors, pressure sensors, RFID readers, QR code readers, and single-chip microcomputers.
    Type: Grant
    Filed: August 20, 2020
    Date of Patent: September 12, 2023
    Assignee: GUANGDONG ZHONGHUI MOBILE LABORATORY TESTING TECHNOLOGY CO., LTD.
    Inventor: Xiaohui Peng
  • Patent number: 11754581
    Abstract: A positioning system (1) that has a system main part (4), on which multiple working units (6) are arranged next to one another in the axial direction of a y-axis, said working units being linearly movable, thereby carrying out a working movement (8) in the axial direction of a z-axis. Each working unit (6) is paired with a dedicated drive unit (7) in order to be actuated, said drive unit having a stator (23) attached to the system main part (4) and an output element (24) drivingly connected to the working unit (6) via a coupling section (26). The stators (23) are distributed into multiple stator rows (58) which are aligned in the axial direction of the y-axis and are arranged one behind the other in the axial direction of the x-axis, wherein the stators (23) of each pair of adjacent stator rows (58) are offset to one another with a mutual overlap in the axial direction of the y-axis.
    Type: Grant
    Filed: November 25, 2020
    Date of Patent: September 12, 2023
    Assignee: Festo SE & Co. KG
    Inventor: Thomas Feyrer
  • Patent number: 11754576
    Abstract: Coordinated conveyors in an automated system. A system comprises a plurality of conveyors, which each comprise a plurality of segments, and one or more stations. An instruction is received to perform an operation that requires at least one station to process at least a first item held by a first segment of a first conveyor and a second item held by a second segment of a second conveyor. In response to the instruction, one or both of the first and second conveyors are moved, such that the first segment and the second segment are aligned at the station. After alignment, one or more instruments of the station process the first item and the second item.
    Type: Grant
    Filed: September 20, 2019
    Date of Patent: September 12, 2023
    Assignee: Team Conveyer Intellectual Properties, LLC
    Inventor: John G. Gorman