Patents Examined by P. Kathryn Wright
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Patent number: 11592395Abstract: The present invention provides a wide-area sample-based reader design which serves as a diagnostic detection device for bio-particles.Type: GrantFiled: March 20, 2020Date of Patent: February 28, 2023Assignee: KAYA17 INC.Inventors: Srinagesh Satyanarayana, Sulatha Dwarakanath
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Patent number: 11585739Abstract: There is provided a nucleic acid extraction method using a cartridge comprising: (a) a driving part of a nucleic acid extraction device is connected to a control rod module disposed in an inner space of the upper body of a piston and a rotation control module coupled to the lower body of the piston; (b) driving the rotation control module and the control rod module, sequentially sucking sample and reagents from the plurality of chambers separated from each other into an interior space, and discharging the mixture of the interior space into the chamber of the cartridge; and (c) driving the rotation control module and the control rod module to suck the reagent inside the master mix bead chamber of the cartridge into the interior space of the piston upper body and then discharge the mixed reagent to a nucleic acid amplification module.Type: GrantFiled: December 20, 2018Date of Patent: February 21, 2023Assignee: SD BIOSENSOR, INC.Inventors: Young Shik Cho, Hyo Guen Lee, Hae Joon Park, Sun Young Lee, Kwan Hun Lim, In Ae Kim, Jae Young Kim, Hyo Lim Park, Dong Hun Kim
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Patent number: 11573243Abstract: Provided is a temperature control system applied to an apparatus for analyzing a sample using a pipette nozzle and a reaction container, including a pipette tip temperature controller that heats a pipette tip which is fitted on the pipette nozzle and aspirates or discharges liquid and a reaction container temperature controller that heats the reaction container. The pipette tip temperature controller heats, in a concentrated manner, at least a distal end portion of the pipette tip of the pipette nozzle located at a predetermined heating position with hot air emitted from a heat source and is configured such that a distal end is capable of arriving at the reaction container by lowering the pipette nozzle from the heating position.Type: GrantFiled: March 2, 2018Date of Patent: February 7, 2023Assignee: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Hiromi Fujii, Teiji Tanaka, Tatsuya Yamazaki, Tomoharu Nakagawa, Tetsuya Noda, Atsuo Iwashita, Yuuya Shouji
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Patent number: 11567090Abstract: An arrangement is provided that is configured to measure a biomarker value of an animal milk sample, including a cassette including a carrier tape having test zones indicating the biomarker value, and an inspective window. The carrier tape is disposed on first and second spools configured to cooperate with a cassette external motor. The arrangement also includes a service module including a camera configured to inspect the test zone, a motor configured to be engaged with a cassette spool, and a tube element configured to provide the milk sample to the test zone.Type: GrantFiled: June 18, 2018Date of Patent: January 31, 2023Assignee: DeLaval Holding ABInventors: Claus Dallerup Rasmussen, Per Sonnich Thomsen
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Patent number: 11565263Abstract: Devices, systems, and their methods of use, for generating droplets are provided. One or more geometric parameters of a microfluidic channel can be selected to generate droplets of a desired and predictable droplet size.Type: GrantFiled: April 6, 2020Date of Patent: January 31, 2023Assignee: 10x Genomics, Inc.Inventors: Rajiv Bharadwaj, Anthony Makarewicz, Bill Kengli Lin
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Patent number: 11559800Abstract: A device for locking a volume adjustment screw for a pipetting system, comprising a control member which rotates as one with a position selector, the member cooperating with a locking wheel such that: when the selector is in the free adjustment position, the member ensures that the wheel is axially spaced from another wheel, such that the teeth of the wheels do not cooperate with each other; when the selector is in the fine adjustment position, the member allows the wheel to move away from and then to move axially towards the other wheel while transitioning from one tooth to another; when the selector is in the locking position, the member axially locks the wheel to prevent the teeth from being disengaged.Type: GrantFiled: April 12, 2019Date of Patent: January 24, 2023Assignee: GILSON SASInventor: Hervé Malvoisin
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Patent number: 11554367Abstract: A pipette for use with a pipette tip includes a housing, a pin on the bottom end of the housing holding a pipette tip having first means for form-fit connection and a second means for form-fit connection which can be shoved onto the pin, constricting the pin, and/or expanding the tip before form-fit connection with the pin, a drive apparatus, at least one locking sleeve arranged concentric to the pin which is guided toward the pin in the housing, wherein the locking sleeve has a locked position having a pin in the inside constricted by shoving on a pipette tip, and/or is bordered on the outside by a tip shoved onto the pin, preventing a release from the pin, and the locking sleeve is upwardly displaceable out of the locked position so that the pin, and/or the tip is released, and the tip is removable from the pin.Type: GrantFiled: January 6, 2020Date of Patent: January 17, 2023Assignee: Eppendorf AGInventors: Martin Seippel, Matthias Kunsch, Burkhardt Reichmuth, Tobias David, Frank Horstmann, Jens Wilmer, Marc Wilth
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Patent number: 11555823Abstract: A medical analysis method uses a medical analysis machine provided with a poly-articulated robot (70) comprising joints defining at least six axes of rotation (A1, A2, A3, A4, A5, A6) and adapted for spacing and/or orienting a terminal member (66) according to six degrees of freedom, the terminal member bearing a grasping member (78) adapted for grasping a container (16). The medical analysis method comprises at least the succession of steps consisting of providing a container (16) containing a sample to be treated stemming from a human being or an animal, transferring said container (16) towards at least one treatment station of the medical analysis machine (100) by means of the poly-articulated robot, treating the sample in a treatment station, transferring the container towards a station for capturing images, and displaying the treatment results through a user interface.Type: GrantFiled: November 14, 2018Date of Patent: January 17, 2023Assignees: BIO-RAD INNOVATIONS, DiaMed GmbHInventors: Jean-Michel Brisebrat, Sébastien Bernay, Cédric Gagnepain, Daniel Seydoux
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Patent number: 11536737Abstract: A flexible instrument control and data storage/management system and method for representing and processing assay plates having one or more predefined plate locations is disclosed. The system utilizes a graph data structure, layer objects and data objects. The layer objects map the graph data structure to the data objects. The graph data structure can comprise one node for each of the one or more predefined plate locations, wherein the nodes can be hierarchically defined according to a predefined plate location hierarchy. Each node can be given a unique node identifier, a node type and a node association that implements the predefined plate location hierarchy. The layer objects can include an index that maps the node identifiers to the data objects.Type: GrantFiled: December 20, 2018Date of Patent: December 27, 2022Inventors: Craig P. Lovell, Thomas Lucas Hampton, III
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Patent number: 11524287Abstract: Aspects of the present disclosure relate to methods and devices for automatically transferring samples and/or reagents from sample vessels and/or reagent vessels into at least one receiving vessel In one example embodiment, a pipetting device is disclosed including a pipettor that is movable along a first direction and has at least one first pipetting needle that is movable along an arm of the pipettor along a second direction, substantially normal to the first direction. The pipetting needle is lowerable along a third direction into the individual vessels. In some specific embodiments, the arm of the movable pipettor has at least one second pipetting needle which, regardless of the current position of the first pipetting needle, is movable past the first pipetting needle and is lowerable into the individual vessels.Type: GrantFiled: July 13, 2018Date of Patent: December 13, 2022Assignee: MEON MEDICAL SOLUTIONS GMBH & CO KGInventors: Berthold Limbach, Wolfgang Sprengers
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Patent number: 11519926Abstract: A microplate processing device having at least one carriage with a first receptacle for microplates where the at least one carriage is movable in a first horizontal direction, and having at least one lift that is movable in a vertical direction, where the microplates can be removed from and supplied to the carriage, the carriage has a through-opening, the periphery, in the vertical projection, can at least in part be situated horizontally within the periphery of a microplate held in the carriage, and the lift has a second receptacle for microplates, the periphery, in the vertical projection, is situated within the periphery of the through-opening, where the second receptacle can be moved unhindered through the through-opening in the vertical direction.Type: GrantFiled: May 25, 2018Date of Patent: December 6, 2022Assignee: TECAN TRADING AGInventors: Johannes Posch, Harald Gebethsroither, Beat Bolli, Gerald Zerza
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Patent number: 11517907Abstract: The system includes a pipette tip with a proximal end that has a rim. The rim defines a proximal opening adapted to receive a pipetter, and the rim includes a rim conical edge. The system also has a support card with a top surface, a pipette tip receiver opening within the top surface, the opening adapted to receive the pipette tip and having a receiver opening conical edge. The rim conical edge and the receiver opening conical edge are constructed such that when the pipette tip is disposed of in the pipette tip receiver opening, the rim conical edge abuts the receiver opening conical edge, and the top surface is flush with or nearly flush with the rim.Type: GrantFiled: September 28, 2021Date of Patent: December 6, 2022Assignee: XCALIBER SCIENCES, INC.Inventor: Arta Motadel
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Patent number: 11511282Abstract: A laboratory sample/specimen temperature control device, specifically a metal bead bath that has its metal bead temperature controlled by a continuous flow of air into the bed of beads that is heated or cooled by a Peltier device that the air flows over. This provides great thermal uniformity across the bed of beads and constantly monitors and regulates the heat or cooling input rather than utilizing an on/off modulation temperature input approach.Type: GrantFiled: October 12, 2020Date of Patent: November 29, 2022Inventors: Josiah Breen, Taylor Rassi
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Patent number: 11511280Abstract: Double bag having a first compartment containing a composition to be distributed and a second compartment for receiving a used fluid, a first bag connector communicating with the first compartment and serving to empty the latter, and a second bag connector communicating with the second compartment and serving to fill the latter.Type: GrantFiled: July 24, 2018Date of Patent: November 29, 2022Assignee: DIAGNOSTICA STAGOInventors: Eric Groussin, Vincent Moutier
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Patent number: 11491479Abstract: A laboratory flask for use in association with a laboratory heating block, having: a flask body, wherein the flask body includes an upper portion, a lower portion, and a sidewall, wherein the sidewall of the flask body includes an inner surface, and an outer surface; a neck, wherein the neck includes an upper portion, a lower portion, and a sidewall, wherein the sidewall of the neck includes an inner surface, and an outer surface, and wherein the neck emanates contiguously from the flask body; and a reservoir, wherein the reservoir includes an upper portion, a lower portion, a bottom wall, and a sidewall, wherein the sidewall of the reservoir includes an inner surface, and an outer surface, and wherein the reservoir is adapted for releasable securement within a laboratory heating block.Type: GrantFiled: January 22, 2020Date of Patent: November 8, 2022Inventor: Rolf Winter
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Patent number: 11305292Abstract: A metering head for a metering machine having a carrier having parallel attachments for picking up pipette tips, wherein each attachment has: a tube having a supporting protrusion at the bottom end, at least one sleeve which surrounds the tube and can be axially shifted on the tube, and at least one elastomer O-ring which surrounds the tube, a pressure plate above the sleeves having a plurality of first holes through which the tubes extend, wherein the pressure plate can be shifted along the tubes from a release position into a clamping position where the sleeves are pressed, at the bottom ends, against the adjacent O-rings, and the O-rings are expanded to clamp pipette tips; and a first shifting apparatus connected to the pressure plate moving the pressure plate between the release position and clamping position.Type: GrantFiled: June 29, 2017Date of Patent: April 19, 2022Assignee: Eppendorf AGInventor: Jens Wilmer
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Patent number: 11211152Abstract: A system and method for managing information relating to requests for a number of tests to be made of at least one sample within a laboratory environment are disclosed. The system may include a sample reception unit, a pre-analytical unit to scan, sort and/or aliquot the sample on request according to respective test requirements included within a respective sample order, an analytical unit to run at least one test on a sorted and/or aliquoted sample, and at least one decision unit. The decision unit acts as a connecting component for interconnecting the sample reception unit, the pre-analytical unit and the analytical unit as both an intermediary and coordinator such that tests can be performed via a recursive workflow until the sample is completely measured. The decision unit is further configured to collate the test results appropriately with the sample and to give a respective report towards a host component.Type: GrantFiled: May 25, 2018Date of Patent: December 28, 2021Assignee: Roche Diagnostics Operations, Inc.Inventors: Ralf Bauer, Werner Schönenberger, Roger Iten
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Patent number: 11204360Abstract: A switch for a conveying line for transporting a laboratory diagnostic vessel carrier is presented. The conveying line comprises a first line portion and a second line portion. The switch comprises a curved first guiding surface and a second guiding surface. The switch is moveable between a first position, in which the laboratory diagnostic vessel carrier is transportable along the curved first guiding surface from the first line portion to the second line portion, and a second position, in which the laboratory diagnostic vessel carrier is further transportable along the second guiding surface on the first line portion. A switch assembly and a conveying line are also disclosed.Type: GrantFiled: June 1, 2018Date of Patent: December 21, 2021Assignee: Roche Diagnostics Operations, Inc.Inventors: David Huber, Daniel Arnold
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Patent number: 10175259Abstract: A laboratory cargo distribution system is presented. The laboratory cargo distribution system comprises a number of transport carriers, a transport plane, a number of electro-magnetic actuators, a storage device and a control device. The storage device is adapted to store at least one of the number of transport carriers. A laboratory automation system comprising such a laboratory cargo distribution system and a method of operating such a laboratory cargo distribution system are also presented.Type: GrantFiled: August 25, 2016Date of Patent: January 8, 2019Assignee: Roche Diagnostics Operations, Inc.Inventor: Christian Riether
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Patent number: 10067152Abstract: An automatic analyzer has a washing tank providing water for washing a reagent or sample probe is. The washing water from a washing nozzle spreads from a throttle portion and is divided into right and left flows after colliding with a vent plate provided in an overflow portion of the washing tank. The washing water flows between the vent plate and the inner wall of the overflow portion, and the flows join behind the vent plate. After joining, the washing water flows downward along the vent plate and the inner wall of the overflow portion and then is drained. Because a space is created between the washing water which has collided with the vent plate and the washing water joined behind the vent plate, the washing water is prevented from completely covering the overflow portion, and the airflow can be secured during the drainage.Type: GrantFiled: January 13, 2015Date of Patent: September 4, 2018Assignee: Hitachi High-Technologies CorporationInventors: Masaru Miyazaki, Takamichi Mori, Kazuhiro Nakamura, Isao Yamazaki