Patents Examined by Robert A. Wax
  • Powder preparation for nasal administration
    Patent number: 11752102
    Abstract: A powder preparation for nasal administration containing a particulate of steroid hormones having an average particle size of 50 to 300 ?m as an active ingredient is prepared.
    Type: Grant
    Filed: December 20, 2021
    Date of Patent: September 12, 2023
    Assignee: ASKA PHARMACEUTICAL CO., LTD.
    Inventors: Koichi Minato, Tomoya Fujisawa, Kenji Shimizu, Takahisa Saito, Hiroya Yajima, Kazuhiro Sasaki
  • N-acetylcysteine compositions and methods
    Patent number: 11752097
    Abstract: Storage stable sterile ready-to-administer formulations comprising N-acetylcysteine are presented with desirable stability characteristics. In preferred aspects, formulations comprise low quantities of one or more chelating agents, contain N-acetylcysteine at a concentration of 25 mg/mL or 50 mg/mL, and are packaged in a suitable format, such as a polymeric bag with a metalized overwrap and a non-contact oxygen scavenger.
    Type: Grant
    Filed: July 5, 2022
    Date of Patent: September 12, 2023
    Assignee: ENDO VENTURES LIMITED
    Inventors: Ronald Domalaon, Jinjiang Li, Tushar Hingorani, Kumaresh Soppimath
  • Hydrogen-containing composition
    Patent number: 11744852
    Abstract: A hydrogen-containing composition for ingestion or topical use and method of producing the hydrogen-containing composition are provided. The composition includes a carrier liquid and molecular hydrogen. The concentration of molecular hydrogen in the carrier liquid is greater than 3 ppm.
    Type: Grant
    Filed: March 19, 2021
    Date of Patent: September 5, 2023
    Assignee: HYEDGE IP COMPANY
    Inventor: Gail Levy
  • Dyed particles with a high pigment content
    Patent number: 11744784
    Abstract: A series of particles, in which each particle contains at least 3 wt. % of pigment(s) in relation to the weight of the particle, a method for producing the series of particles, and uses thereof in cosmetic compositions, particularly in make-up for keratinous materials.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: September 5, 2023
    Assignee: CAPSUM
    Inventors: Julie Cani, Cassia Michel, Morgane Forest
  • Kombucha natural health products
    Patent number: 11744871
    Abstract: Kombucha tea faces many challenges concerning its use for its health benefits, such as standardization, as well as the determination of a specific dosage form appropriate to the intended use. Kombucha tea, as a fermented, alcohol-containing beverage that relies on a complex combination of living yeast and bacteria for production, is especially difficult to administer. The present invention provides a consistent, standardized dosage form and novel combinations of a traditional medicinal drink that is otherwise unsuitable for widespread natural medicine. By providing kombucha as a soft, chewable and orally dissolvable and/or disintegrable compositions, such as a gummie, a gummie with probiotics, or a gummy made from tapioca syrup, a unique, desirable flavor and mouthfeel is obtained and which is also alcohol free. This expands the number of people who can enjoy the benefits of the traditional tea.
    Type: Grant
    Filed: May 31, 2022
    Date of Patent: September 5, 2023
    Assignee: VIVA NATURALS, INC.
    Inventors: Ashley Kasurak, Husayn Remtulla
  • Injectable pharmaceutical formulation
    Patent number: 11744798
    Abstract: An injectable pharmaceutical formulation includes nanofibrillar cellulose hydrogel wherein the content of nanofibrillar cellulose in the pharmaceutical formulation is the range of 1-8% (w/w), and pharmaceutical compound. The injectable pharmaceutical formulation can provide a sustained release of a pharmaceutical compound in a subject. Use of nanofibrillar cellulose for preparing the injectable pharmaceutical formulation is also disclosed.
    Type: Grant
    Filed: September 9, 2020
    Date of Patent: September 5, 2023
    Assignee: UPM-KYMMENE CORPORATION
    Inventors: Markus Nuopponen, Lauri Paasonen, Anne Meriluoto, Jukka Rissanen, Harri Jukarainen
  • Rapamycin for the treatment of lymphangioleiomyomatosis
    Patent number: 11744797
    Abstract: The present invention relates to methods and compositions for treating lymphangioleiomyomatosis in a human subject in need of such treatment. The methods comprise administering to the subject via inhalation an aerosol composition comprising rapamycin or a prodrug or derivative (including analog) thereof.
    Type: Grant
    Filed: August 27, 2021
    Date of Patent: September 5, 2023
    Assignee: AI Therapeutics, Inc.
    Inventors: Henri Lichenstein, Jonathan M. Rothberg, Thomas Armer, Lawrence S. Melvin, Jr.
  • Methods and devices for controlled delivery
    Patent number: 11744729
    Abstract: Disclosed herein are exemplary medical devices for controlled delivery of material compositions, particularly occlusive, therapeutic, or diagnostic compositions.
    Type: Grant
    Filed: May 2, 2019
    Date of Patent: September 5, 2023
    Assignee: FEMASYS INC.
    Inventor: Kathy Lee-Sepsick
  • Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
    Patent number: 11738033
    Abstract: Methods, compositions, and kits for adjunctive therapy using 25-hydroxyvitamin D are disclosed. The 25-hydroxyvitamin D may be administered with an agent that increases the risk of hypocalcemia, such as cinacalcet or a salt thereof, and/or an anticancer agent. The adjunctive therapy is effective to treat and prevent iatrogenic hypocalcemia and/or secondary hyperparathyroidism, as well as delay cancer progression and the time to a post-treatment skeletal related event.
    Type: Grant
    Filed: May 11, 2021
    Date of Patent: August 29, 2023
    Assignee: EIRGEN PHARMA LTD.
    Inventors: P. Martin Petkovich, Joel Z. Melnick, Jay A. White, Samir P. Tabash, Charles W. Bishop, Susan Peers, Stephen A. Strugnell
  • Time-dependent synthetic biological barrier material
    Patent number: 11739452
    Abstract: Thermally stable absorbable fiber populations, i.e. fiber populations that do not undergo thermally induced crystallization, can be intermixed to yield a stabilizing effect without altering morphological properties of a first fiber system. By addition of a stabilizing fiber population one may minimize thermally induced shrinkage and maintain physical properties of electrospun materials in the as-formed state. In one particular abstract, medical barrier materials may be formed from the electrospun materials to provide improved medical barriers for treatments.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: August 29, 2023
    Assignee: Poly-Med, Inc.
    Inventors: Michael Scott Taylor, Seth Dylan McCullen, David Shalaby
  • Imaging agents and methods of using the same
    Patent number: 11730831
    Abstract: A composition for internal imaging of a subject includes an imaging contrast agent and one or more carrier agents that can pass through cellular and tissue membranes. Examples of imaging contrast agents are iodine-based, silver-based, or barium-based. Examples of carrier agents are dimethyl sulfoxide, urea, or an alcohol. Methods for internally imaging a subject using such a composition are also disclosed.
    Type: Grant
    Filed: March 26, 2020
    Date of Patent: August 22, 2023
    Assignee: SICREATIONS, LLC
    Inventor: Michael Scott Echols
  • Hydrogel devices and methods of making and use thereof
    Patent number: 11730861
    Abstract: Disclosed herein are hydrogel devices and methods of making an use thereof. The devices can comprise: a continuous hydrogel matrix; a first chamber in the hydrogel matrix; and a second chamber in the hydrogel matrix; wherein the first chamber and the second chamber are each independently perfusable; wherein the first chamber is fluidly independent from the second chamber; wherein the first chamber is configured to be at least partially filled with adipose tissue; wherein the second chamber is configured to be at least partially filled with an oxygenated fluid; wherein the first chamber is defined by a first border; wherein the second chamber is defined by a second border; and wherein the first chamber and the second chamber are spaced apart from each other by an average distance of from 50 micrometers (microns, ?m) to 800 ?m as measured from the first border to the second border.
    Type: Grant
    Filed: July 26, 2022
    Date of Patent: August 22, 2023
    Assignee: The Methodist Hospital System
    Inventor: Aldona Jedrysiak Spiegel
  • Solid pharmaceutical tablet
    Patent number: 11730757
    Abstract: The invention relates to a solid pharmaceutical tablet for oral delivery, the tablet comprising calcium carbonate in an amount of more than 30% by weight of the tablet and organic water-insoluble components in an amount of more than 20% by weight of the tablet, wherein the tablet is designed to be masticated into a coherent residual containing the organic water-insoluble components, and wherein the tablet is adapted to release more than 80% of the calcium carbonate within 5 minutes of mastication.
    Type: Grant
    Filed: March 21, 2019
    Date of Patent: August 22, 2023
    Assignee: Fertin Pharma A/S
    Inventor: Jesper Neergaard
  • Stable liquid pharmaceutical preparation
    Patent number: 11730698
    Abstract: A stable liquid pharmaceutical formulation according to the present invention includes an antibody or antigen-binding fragment thereof, a surfactant, a sugar or a sugar derivative, a buffer, and a stabilizer. The stable liquid pharmaceutical formulation according to the present invention has low viscosity not only when antibody content is low but also when antibody content is high, and exhibits superior long-term storage stability based on superior stability observed under accelerated conditions and harsh conditions.
    Type: Grant
    Filed: July 18, 2019
    Date of Patent: August 22, 2023
    Assignee: CELLTRION INC.
    Inventors: So Young Kim, Yeon Kyeong Shin, Hye Young Kang, Kwang Woo Kim, Jun Seok Oh, Su Jung Kim, Joon Won Lee, Won Yong Han, Jae Bin Lee, Ji Won Roh, Ji Min Kwak
  • Antimicrobial-antibiofilm compositions and methods of use thereof for personal care products
    Patent number: 11723852
    Abstract: Compositions comprising one or more chelating agents and optionally zinc ion salts are used to inhibit the growth or biofilm formation in bacteria associated with personal care products such as ophthalmic, pedicure, manicure or podiatric solutions. The compositions of the present application can also comprise gelling agents, antimicrobials, antibiotic or a pH adjuster. The compositions may be in the form of a solution, a gel, a cream, a jelly, a powder, a paste, a lotion, soap and a cleaner.
    Type: Grant
    Filed: August 3, 2021
    Date of Patent: August 15, 2023
    Assignee: KANE BIOTECH INC.
    Inventors: Purushottam V. Gawande, Karen Lovetri, Nandadeva Yakandawala, Gord Froehlich, Srinivasa Madhyastha
  • Pharmaceutical solution of amlodipine
    Patent number: 11723866
    Abstract: Disclosed herein is a liquid pharmaceutical formulation substantially free of water, comprising: (i) amlodipine or a pharmaceutically acceptable salt thereof, (ii) at least one pharmaceutically acceptable excipient, and (iii) a sufficient amount of a vehicle comprising glycerin. Also disclosed herein is a liquid pharmaceutical formulation substantially free of water and ethanol, comprising: (i) amlodipine or a pharmaceutically acceptable salt thereof, (ii) at least one pharmaceutically acceptable excipient, and (iii) a sufficient amount of a vehicle comprising glycerin.
    Type: Grant
    Filed: June 15, 2022
    Date of Patent: August 15, 2023
    Assignee: LIQMEDS WORLDWIDE LIMITED
    Inventors: Jayanta Kumar Mandal, Malay Patel, Swati Nagar, Michael Paul DeHart
  • Poly(meth)acrylic acid popcorn polymerizates as disintegrants for tablets
    Patent number: 11723871
    Abstract: The use of powder-form, crosslinked, water-insoluble, low-swelling polyacrylates as disintegrants for solid pharmaceutical dosage forms.
    Type: Grant
    Filed: May 15, 2019
    Date of Patent: August 15, 2023
    Assignee: BASF SE
    Inventors: Theo Smit, Matthias Karl, Felicitas Guth, Maximilian Angel, Karl Kolter, Frank Schmidt, Maximilian Blochberger-Claus
  • Reduction of flake-like aggregation in nanoparticulate active agent compositions
    Patent number: 11717481
    Abstract: This invention is directed to reduction of flake-like aggregation in nanoparticulate compositions. Also encompassed by the invention are compositions comprising a nanoparticulate active agent, at least one surface stabilizer and a flake-like aggregation reducing agent, such as a buffer and a sugar. The nanoparticulate active agent compositions comprise particles of the active agent having an effective average particle size of less than about 2000 nm.
    Type: Grant
    Filed: December 3, 2021
    Date of Patent: August 8, 2023
    Assignee: ALKERMES PHARMA IRELAND LIMITED
    Inventors: Niels P. Ryde, Peter Snyder, Wei Liu, David M. Slifer
  • Solid nanoparticle with inorganic coating
    Patent number: 11717491
    Abstract: A nanoparticle having a solid core comprising a biologically active substance, said core being enclosed by an inorganic coating, a method for preparing the nanoparticle, and the use of the nanoparticle in therapy. A kit comprising the nanoparticle and a pharmaceutical composition comprising the nanoparticle.
    Type: Grant
    Filed: November 12, 2020
    Date of Patent: August 8, 2023
    Assignee: NANEXA AB
    Inventors: Jan-Otto Carlsson, Anders Johansson, Marten Rooth
  • Therapeutic nanocarrier system and methods of use
    Patent number: 11717490
    Abstract: A nanoparticle for treatment of cancer is provided comprising a poloxamer surfactant, a Vitamin E TPGS and an anticancer compound.
    Type: Grant
    Filed: June 4, 2021
    Date of Patent: August 8, 2023
    Assignee: UNIVERSITY OF CYPRUS
    Inventors: Yiota Gregoriou, Gregoria Gregoriou, Andreas I. Constantinou