Abstract: Dosage units, such as tablet cores and granules, containing a composition comprising a steroid having two hydrogen atoms at position 3 of the steroid skeleton, are coated. While a conventional sugar coating process involves the application of several layers including, as a surface layer, a sugar coat, it was found that a seal coat such as normally used in a sugar coating process can be used as the surface layer for the purpose of preventing the transfer of the steroid out of the composition. From this novel use of a seal coat, novel dosage units result. The process is advantageous, as it requires fewer steps than before.

Abstract: In accordance with the present invention, there are provided compositions and methods useful for the in vivo delivery of a pharmaceutically active agent, wherein the agent is associated with a polymeric biocompatible material.

Abstract: A consumer article comprising a hand-held spray container, and a sprayable composition contained within the spray container comprising ethanol or isopropanol and methyl acetate or t-butyl acetate, a hair care composition comprising a fixative, ethanol, and methyl acetate or t-butyl acetate, and a method of fixing hair comprising spraying the compositions of this invention onto hair.

Abstract: The present invention concerns pulverulent mannitol characterized in that it has an average diameter of between 60 and 200 &mgr;m, preferably of between 80 and 180 &mgr;m, a packed density, determined according to a Test A, of between 0.65 and 0.85 g/ml, preferably of between 0.7 and 0.8 g/ml and a flow factor of at least 60, preferably of between 60 and 90a process for obtaining and using the said pulverulent mannitol as an excipient in preparations intended in particular for the pharmaceutical field, and especially as a powder for filling hard capsules.

Abstract: A highly safe bone resorption suppressing agents, which can be used as medicines or admixed to food products or feeds, is produced. Milk-derived basic cystatins and/or milk-derived basic cystatin decomposition products prepared from milk are made into bone resorption suppressing agents, or admixed to drinks, food products and feeds.

Abstract: The invention provides methods and materials for improving or maintaining hair care. Such hair care compositions can contain a macrocyclic lactone and/or an eicosanoate ester. In addition, the hair care compositions can contain a grape skin extract, a benzophenone, and/or an aryl benzotriazole. Further, the hair care methods and materials can provide increased hair manageability as well as protection against sun exposure (e.g., exposure to ultraviolet radiation) and repeated chemical treatment.

Abstract: A paper product that is applied with a lotion composition is provided. In one embodiment of the present invention, the lotion composition includes water in an amount up to about 90% by weight of the lotion, an emollient component in an amount up to about 20% by weight of the lotion, a fatty alcohol component in an amount up to about 50% by weight of the lotion, an emulsifier component in an amount up to about 40% by weight of the lotion, and a skin conditioning component in an amount up to about 60% by weight of the lotion. Typically, the add-on level of the lotion composition is between about 1% to about 15% by weight of the paper product. As a result, the paper product can be used to dry the hands of a user, while also imparting certain benefits to the skin as well.

Abstract: A process of preparing solid form of an extract of a raw material, obtained by subjecting the raw material to extraction utilizing a heating, extracting and condensing system, and contacting the resulting liquid extract with an absorbent material or a food, and drying the wetted absorbent material or food such as by freeze drying.

Abstract: The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in one or more non-aqueous and/or water-miscible solvents, or optionally, in a premix of one or more solvents and one or more surfactants.

Abstract: Healing of mucosa injury is promoted by applying thereto a membrane of purified collagen material derived from natural collagen-containing tissue.

Abstract: Antimicrobial and contraceptive compositions and methods which prevent and/or reduce the risk of transmission of sexually transmitted diseases through sexual activity as well as prevent and/or reduce the risk of pregnancy are provided.

Abstract: Provided herein is a disinfectant wound dressing for treating tissue wounds, said dressing comprising a hydrogel matrix including an absorbent fibrous material comprising alginate salt, said hydrogel matrix being loaded with absorbed components comprising a hydrocolloid moisture retaining component, a salt component compatible with the tissue being treated, and a vulnerary polysacharide component being therapeutically acceptable with regard to wound tissue irritation level and systemic toxicity level. The wound dressing will optionally contain a further disinfectant component.

Abstract: Sucralfate gel in the dry state in porous granular form having a particle-size distribution of between 100 and 1000 &mgr;m, an apparent density of the powder bed of between 0.7 and 0.9 g/ml, a settling index of between 5 and 15%, and a residual humidity of between 5 and 15%, and the corresponding process of preparation, which comprises a treatment with microwaves of a diluted solution of powdered sucralfate gel, with a sucralfate titre of between 20 and 70 wt. %. This solid product may be advantageously used in the preparation of solid pharmaceutical compositions that contain it as single active principle, or else as coating of solid compositions that contain, as active principle, a substance that may cause lesions to the gastric mucosa.

Abstract: The present invention relates to a novel solid pharmaceutical formulation containing lovastatin and simvastatin, respectively, with a particle size D(0.9) between 15 and 100 &mgr;m and a specific particle surface area between 1 and 4 m2/g, and to the process for its preparation. The present invention also relates to the method for production of lovastatin and simvastatin with the size of crystals which are suitable for the preparation of the pharmaceutical formulation of the present invention. The novel solid pharmaceutical formulation is useful for treating hypercholesterolemia and hyperlipidemia.

Abstract: The invention is directed to a pharmaceutical composition of topiramate an anticonvulsant which is useful for treating epilepsy. More specifically, the present invention provides a solid dosage formulation of topiramate intended primarily for use by pediatric patients, or for patients who have difficulty swallowing tablets. Processes for preparing the pharmaceutical composition are also described.

Abstract: A moisturizing and therapeutic glove is disclosed which includes a thin layer of Aloe Vera coated evenly and uniformly on an inside surface of the glove. Aloe Vera is attached to the surface through a dehydration process achieved with a controlled drying method. Aloe Vera soothes the hand during the wearing of the glove.

Abstract: The present invention is an improvement in the treatment of migraine headaches. By administering dihydroergotamine as a sublingual spray or aerosol, major limitations of past treatments are circumvented thereby allowing for higher efficacy and fewer side effects of treatment at lower doses.

Abstract: A method of making antacid coated chewing gum products comprises the steps of providing chewing gum cores; providing a coating syrup comprising a bulk sweetener, calcium carbonate and a binding agent; and applying the coating syrup to the cores and drying the syrup to produce a sugarless coating on the cores. The coating on the cores produces a high viscosity in saliva when the gum is chewed, in that 4.5 grams of said coating dispersed in 30 ml of water has a Brookfield viscosity at 23° C. of at least 1.6 centipoise.

Abstract: Modified amino acid compounds useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well.

Abstract: A nutritional or dietary supplement composition that strengthens and promotes retinal health through the prevention, stabilization, reversal and/or treatment of visual acuity loss by reducing the risk of developing late stage or advanced age-related macular degeneration in persons with early age-related macular degeneration. The nutritional or dietary supplement composition may likewise reduce the risk of vision loss associated with the development of cataracts. The essential ingredients of the nutritional or dietary supplement composition are vitamin C, vitamin E, beta-carotene, zinc and copper. The essential ingredients are preferably provided in a tablet form suitable for oral ingestion. Preferably the composition is taken in the form of one or two tablets taken twice daily.