Abstract: This disclosure relates to symmetric tubing clamps for blood treatment systems and related systems and methods. In some aspects, a tubing clamp includes a resilient body that has symmetry with respect to a first plane with a normal along a longitudinal axis of the resilient body, the resilient body comprising a sidewall defining an opening such that a tubing is arrangeable through the opening along the longitudinal axis of the resilient body; first and second snap-fit features configured to engage with each other when the resilient body is compressed along a direction transverse to the longitudinal axis; and a protrusion configured to constrict the tubing when the resilient body is compressed along the direction transverse to the longitudinal axis.

Abstract: A medical treatment system, such as a peritoneal dialysis system, may include a control and other features to enhance patient comfort and ease of use. For example, a cycler device may include a heater bag receiving section and a lid mounted to cover and uncover the heater bag receiving section, potentially enabling faster heating of a dialysate. A user interface may be moveable to be received into the receiving section and covered by the lid, if desired. The system may detect anomalous conditions, such as tilting of a housing of the system, and automatically recover without terminating a treatment. The system may include noise reduction features, such as porting pneumatic outputs to a common chamber, and others. The system may also automatically detect any one of several different solution lines connected to the system, and control operation accordingly, e.g., to mix solutions provided by two or more lines and form a needed dialysate solution.

Abstract: An injection system includes a molded body member having a body connection member at a distal end of the molded body member. The system also includes a needle hub assembly coupled to the distal end of the molded body member. The needle hub assembly includes a needle hub coupled to the body connection member of the molded body member, a needle coupled to the needle hub, and a barbed band disposed around a proximal end of the needle hub and having a barb. The barbed band allows rotation of the needle hub assembly relative to the body connection member in a first direction, while preventing rotation of the needle hub assembly relative to the body connection member in a second direction.

Abstract: A medical device having an antimicrobial coating on a surface of the medical device and an inserter device for subcutaneously inserting the medical device. The inserter device includes an outer part having one or more locking elements including a first locking element and one or more release elements including a first release element; a housing; and a functional part accommodated in the housing. The housing includes a sidewall with an inner surface forming a cavity, the housing extending from a first end to a second end along a first axis and comprising one or more housing guide members including a first housing guide member for engagement with one or more guide members of the functional part. The functional part comprises a first part with a first body extending from a first end to a second end along the first axis.

Abstract: A warming unit (21) coupled or configured to be coupled to a heated portion (19) of a fluid circuit (6, 7, 10, 11, 13, 14, 15; 107) of a medical device (1, 100). The warming unit (21) comprises a leakage current reduction circuit (35) configured to perform the following procedure: connecting a heat transfer element (22) of the warming unit (21) to a ground connection (33) through a resistance element (34), which keeps a normal condition patient leakage current below a first limit value, and disconnecting the heat transfer element (22) from the ground connection (33) if a current indicating that a patient is connected to a mains voltage is sensed through the resistance element (34), in order to keep a fault condition patient leakage current below a second limit value.

Abstract: A device for generating microbubbles may include a syringe having a barrel, a plunger and a syringe tip; a converging nozzle; and an aerator. The converging nozzle may have a coupling end, a converging tip opposite the coupling end, an exterior mating surface adjacent the converging tip, and an interior channel that fluidly couples the syringe tip and the converging tip. The interior channel may have a diameter that progressively decreases from the coupling end to the converging tip. The converging nozzle may be coupled to the syringe tip. The aerator may have a retention end, a discharge end, an interior air chamber, an interior circumferential lip, and a discharge channel at the discharge end. The retention end may be coupled to the converging nozzle. The interior circumferential lip may abut the exterior mating surface. One or more air channels may fluidly couple the discharge channel and the interior air chamber.

Abstract: A flush syringe for use in maintaining intravenous catheters, wherein the flush syringe can more efficiently and effectively flush the catheters by providing a pulsating, pulsatile, and/or pulsative flow of fluid that can be produced using momentum of the fluid moving. A steady force applied to a plunger while flushing can provide the pulsating, pulsatile, and/or pulsative flow of the fluid to the catheters.

Abstract: An intravascular ultrasound (IVUS) catheter-based device for targeted delivery of ultrasound-activated emulsions of oxygen-scavenging droplets into a bloodstream of patients suffering from a hypoxic condition and methods utilizing the device to protect the patients from reperfusion injury upon restoration of oxygenated blood to a hypoxic tissue.

Abstract: A phacoemulsification tip, including an aspiration tube presenting a cutting tip at a distal end. The aspiration tube has a tube wall presenting an internal face and an external face. The internal face supports at least one internally extending internal ridge. The at least one internal ridge presents an internal distal face, an internal proximal face and an internal apex. The internal distal face meets the internal face at an acute angle measured internally. The at least one internal ridge is structured to engage lens fragments separated from a crystalline lens to enhance proximal movement of the lens fragments and to inhibit distal movement of the lens fragments through the aspiration tube.

Abstract: A catheter assembly includes: a hollow catheter; a catheter hub to which the catheter is fixed; an inner needle including a needle tip, the inner needle being detachably disposed inside of the catheter; a needle hub to which the inner needle is fixed; a catheter operation member configured to move the catheter relative to the inner needle; and a support member disposed at the needle hub and configured to rotate about a rotation axis orthogonal to a longitudinal direction of the assembly. The support member includes a support main body portion that projects in a direction orthogonal to the rotation axis of the support member and that is movable relative to the needle hub between (i) a first position at which the support main body portion contacts and supports the catheter, and (ii) a second position at which the support main body portion does not contact the catheter.

Abstract: The present invention relates to a breast status determination device (10?). The breast status determination device (10?) comprises a breast shield (16?), a nipple elongation measurement unit (17?), and a breast status determination unit (20?). The breast shield (16?) can receive abreast (12) of a user (14) therein. The nipple elongation measurement unit (17?) can measure an elongation of a nipple of the breast (12) received in the breast shield (16?) for a specific pressure in the breast shield (16?) during a milk extraction session. The breast status determination unit (20?) can determine a status of the breast (12) based on the elongation of the nipple (26). The breast status determination device (10?) can allow estimating of milk left in the breast during the milk extraction session, when the breast (12) is empty, and whether a milk ejection reflex is present or absent in the breast (12).

Abstract: An infusion flow regulator includes: a main body having an inlet through which fluid is introduced and an outlet through which the fluid is discharged; and a rotary dial rotatably coupled to the main body, with a sealing member interposed therebetween, so as to regulate a flow rate of the fluid, in which the rotary dial includes a regulating flow path having a shape of a recessed groove in cross section with a first width and a first height, and the regulating flow path includes a first region in which the first width is constant and the first height is decreased, and a second region in which both the first width and the first height are decreased. By the aforementioned configuration, the infusion flow regulator for the fluid can accurately regulate the flow rate even in a region where the flow rate of the fluid is very small.

Abstract: An injection method is provided for using an injection pen, the injection pen comprising a housing, a lead screw axially moveable in the housing, a dose set member for dose setting and dose correcting, threadably connected to the housing and having a first mating feature, a setback member having a second mating feature for engaging the first mating feature, a clicker that generates an audible or tactile indication during operation, the clicker being operatively connected to the dose set member, and a push button operatively connected to the setback member to cause the second mating feature to engage the first mating feature during an injection, the push button receiving the clicker, wherein the first mating feature is disengaged from the second mating feature during the dose setting and the dose correcting and engaged with the second mating feature during the injection.

Abstract: A peritoneal dialysis (“PD”) system includes a cycler including an actuation surface having a peristaltic pump actuator; a manifold assembly including a rigid manifold having first and second chambers (110a, 110b), the rigid manifold configured and arranged to be abutted against the actuation surface for operation, a peristaltic pump tube (124gh) extending from the first chamber (110a) to the second chamber (110b) of the rigid manifold, a dialysis fluid container line (124b) extending from the first chamber (110a), and a branch line (124c) extending between the dialysis fluid container line (124b) and the second chamber (110b); and a control unit configured to cause the peristaltic pump actuator to actuate the peristaltic pump tube (124gh) to pump dialysis fluid from the branch line (124c) into the second chamber (110b) and from the second chamber (110b) into the first chamber (110a).

Abstract: The present disclosure relates to a cap for an injection device. The injection device comprises a body for holding a syringe having a needle extending from an end thereof. The cap is removably attachable to the body. The cap comprises an actuator and a needle shield to cover said needle. The cap further comprises a coupling between the actuator and the needle shield. The coupling is configured such that when the cap is attached to the body of the injection device axial movement of the actuator away from the body causes rotation of the needle shield relative to the body.

Abstract: Infusion devices, systems, and methods can for detecting a presence or an absence of an infusion cartridge in an infusion pump. Embodiments may include a loading sequence, recording loading pulse width modulation (PWM) commands applied to an infusion pump motor during the loading sequence, setting a value of threshold PWM commands based on the loading PWM commands applied during the loading sequence and comparing values of operational PWM commands applied during pumping operations to the value of the threshold PWM commands. If the values of the operational PWM commands drops below the value of the threshold PWM commands by a predetermined amount, a missing infusion cartridge warning may be generated.

Abstract: A catheter having a catheter shaft that has a more uniform construction throughout a length of the catheter shaft and is able to provide more than one deflection curvature. The catheter shaft includes a flexible outer tubular member, and a less flexible inner tubular member extending through the outer tubular member in a proximal section of the catheter shaft, wherein the inner tubular member is afforded longitudinal movement relative to the outer tubular member. The catheter also includes at least one puller wire extending through the inner tubular member to deflect a distal deflection section of the catheter shaft, wherein the longitudinal movement of the inner tubular member relative to the outer tubular member enables an operator to select and set a deflection curvature of the distal deflection section.

Abstract: An apparatus for delivering a fluid to a subject through infusion tubing (22). The apparatus includes a tube cassette (20) for receiving the infusion tubing. The tube cassette has an anti-free-flow valve (26) configured to (i) occlude the infusion tubing, and (ii) be actuated by a force external to the tube cassette to terminate the occlusion of the infusion tubing. The tube cassette is configured to be removably coupled to a pump (24). The pump is configured to, as part of a pumping cycle for delivering the fluid to the subject, repeatedly (a) actuate the anti-free-flow valve to terminate the occlusion of the infusion tubing, and subsequently (b) release the anti-free-flow valve to occlude the infusion tubing. Other applications are also described.

Abstract: A medical device, such as an electrophysiology catheter, has an elongate body including a wall. A reinforcing layer is encapsulated in the wall. The reinforcing layer includes one or more reinforcing fibers having glass cores and polymer claddings. In embodiments, the one or more reinforcing fibers are non-magnetically-susceptible and non-electrically-conductive, facilitating use of the medical device in connection with procedures such as magnetic resonance imaging (“MRI”).

Abstract: A fluid management and medical device system may include a fluid management system and a medical device. The fluid management system may include a pump configured to pump fluid to the medical device and a processing device configured to control the pump to maintain a target fluid flow range. The medical device may include an elongate shaft in fluid communication with the pump of the fluid management system, a pressure sensor, and a workstation in electronic communication with the pressure sensor and the processing device of the fluid management system. The processing device may be configured to adjust a fluid flow rate based on data received from the pressure sensor of the medical device and configured to verify the medical device is in a patient's body prior to adjusting the fluid flow rate based on the data received from the pressure sensor.