Abstract: A medical device, such as an electrophysiology catheter, has an elongate body including a wall. A reinforcing layer is encapsulated in the wall. The reinforcing layer includes one or more reinforcing fibers having glass cores and polymer claddings. In embodiments, the one or more reinforcing fibers are non-magnetically-susceptible and non-electrically-conductive, facilitating use of the medical device in connection with procedures such as magnetic resonance imaging (“MRI”).

Abstract: A fluid management and medical device system may include a fluid management system and a medical device. The fluid management system may include a pump configured to pump fluid to the medical device and a processing device configured to control the pump to maintain a target fluid flow range. The medical device may include an elongate shaft in fluid communication with the pump of the fluid management system, a pressure sensor, and a workstation in electronic communication with the pressure sensor and the processing device of the fluid management system. The processing device may be configured to adjust a fluid flow rate based on data received from the pressure sensor of the medical device and configured to verify the medical device is in a patient's body prior to adjusting the fluid flow rate based on the data received from the pressure sensor.

Abstract: An injection device for injecting, the injection device comprising a housing having an interiorly facing wall with the wall having a plurality of ribs formed thereon, the ribs defining a channel extending therebetween, a plunger rod mountable within the housing and having at least one protrusion engageable within the channel, a cylindrical body, a spring mounted at a distal end of the housing with the spring being biased between the distal end and a needle hub, and a pusher rod raised such that pressure thereon from the plunger rod will cause the pusher rod to enter the cylindrical body, the pressure causing the spring to act on the needle hub to move the needle hub and the cylindrical body upwardly within the housing such that a needle is in an enclosed position within the housing and cannot be reused.

Abstract: A medicament injection device comprising a main body arranged to receive a medicament cartridge; a needle carrier carrying a needle, wherein the needle carrier is axially movable with respect to the main body; and a rotatable cap at a distal end of the device, wherein the cap is removably coupled to the needle carrier, a releasable arrangement between the main body and the cap comprising a guide element and a slotted link, wherein the slotted link is arranged to cause the guide element to follow a predefined path at least partly in an axial direction during rotational movement of the cap, thereby causing the needle carrier to move axially towards a proximal end of the device as the cap is rotated up to a predefined point, wherein the main body comprises a medicament cartridge holder comprising the guide element depending therefrom for engagement with the cap.

Abstract: A liquid medicine injection device includes: a liquid medicine storage unit including a cylinder including a space configured to store liquid medicine therein and a discharge hole connected to the space, and a piston arranged inside the cylinder and moving toward the discharge hole depending on discharge of the liquid medicine; a first electrode on an outer surface of the cylinder; a second electrode on the outer surface of the cylinder, the second electrode facing the first electrode with the piston therebetween; and a circuit unit including a substrate electrically connected to the first electrode and the second electrode.

Abstract: A medicament injection device comprising a main body arranged to receive a medicament cartridge; a needle carrier carrying a needle, wherein the needle carrier is axially movable with respect to the main body; and a rotatable cap at a distal end of the device, wherein the cap is removably coupled to the needle carrier, a releasable arrangement between the main body and the cap comprising a guide element and a slotted link, wherein the slotted link is arranged to cause the guide element to follow a predefined path at least partly in an axial direction during rotational movement of the cap, thereby causing the needle carrier to move axially towards a proximal end of the device as the cap is rotated up to a predefined point, wherein the main body comprises a medicament cartridge holder comprising the guide element depending therefrom for engagement with the cap.

Abstract: The present disclosure concerns embodiments of multi-lumen cannulae that can be used in various different medical procedures. The multi-lumen cannulae can comprise an elongated body comprising multiple different ports that connect to various different sidewall lumens contained within the elongated body. The multi-lumen cannulae can also comprise a central lumen that extends through the entire elongated body and can be fluidly connected to the various different sidewall lumens. The multi-lumen cannulae can further comprise two balloons on an exterior of the elongated body, which can be used to isolate a right atrium of a patient's heart.

Abstract: Various implementations include a mixing vial for use in a cartridge syringe. The mixing vial includes a vessel, a stopper, and a dislodgeable plug. The stopper includes an open first end, a closed second end, and a stopper side wall. A hollow interior chamber is defined by the stopper side wall and the closed second end. The stopper is positioned in a sealing relationship with an inner surface of the vessel. An outer surface of the stopper side wall includes two ribs extending radially outwardly from the stopper side wall. Each of the two ribs is axially spaced apart from each other. An inner surface of the stopper side wall defines an annular groove located axially between the two ribs. The dislodgeable plug is disposed within the hollow interior chamber of the stopper such that an edge of the dislodgeable plug is disposed within the groove of the stopper.

Abstract: In one embodiment there is an injector comprising a housing having a proximal end and a distal end, a shell, a plunger, a needle guard, a first member, and an actuation assembly. The shell may be within the housing and may have a cavity to receive at least a portion of a medicament chamber. The shell may be moveable with respect to the housing from an initial position to an injecting position. The plunger may be moveable with respect to the shell. The needle guard may be moveable between an extended position and a retracted position. The first member may be within the housing. The actuation assembly may be coupled to the housing and the shell. The needle guard may move the first member with respect to the housing as the needle guard moves from the extended position to the retracted position. The actuation assembly may move the shell from the initial position to the injecting position when the first member moves with respect to the housing.

Abstract: An intraosseous needle includes a cylindrical shaft. The cylindrical shaft includes a first portion comprising a plurality of threads protruding from the cylindrical shaft. The cylindrical shaft includes a second portion comprising a plurality of fenestrations, disposed between the first portion and a distal end of the cylindrical shaft, wherein the cylindrical shaft is continuous and smooth within the second portion, and where the continuous, smooth second portion is longer than the first portion. The intraosseous needle also includes a needle head extending from a proximal end of the cylindrical shaft.

Abstract: A fluid flow control valve includes a valve body with a fluid flow lumen therethrough and a valve member located within the fluid flow lumen. At least one of the valve body and the valve member is resilient and respectively sized for movement between a normally closed position in which the valve member and a fluid lumen surface are in sufficient annular contact to block fluid flow through the fluid flow lumen and an open position in which at least one of the valve body and the valve member flexes to a spaced apart position that allows the fluid flow between the valve body and the valve member. Downstream fluid pressure may contact the valve body to enhance sealing. A fluid absorbent member may also be employed with the valve body. Flow control devices, such as medical fluid injection devices, and methods may employ the valve.

Abstract: A fluid handling cassette, such as that useable with an automated peritoneal dialysis (APD) cycler device or other infusion apparatus, may include a generally planar body having at least one pump chamber formed as a depression in a first side of the body and a plurality of flowpaths for a fluid that includes a channel. A patient line port may be arranged for connection to a patient line and be in fluid communication with the at least one pump chamber via at least a first one of said flowpaths, and an optional membrane may be attached to the first side of the body over the at least one pump chamber. In one embodiment, the membrane may have a pump chamber portion with an unstressed shape that generally conforms to the depression of the at least one pump chamber in the body and is arranged to be movable for movement of the fluid in a useable space of the at least one pump chamber.

Abstract: A reusable needle handling apparatus is described. The needle handling apparatus is configured for receiving at least a portion of a syringe assembly including at least a needle, a needle cap, and a syringe hub. The needle handling apparatus includes a first clamping mechanism having a plurality of pinch rollers. According to an aspect, the pinch rollers are configured to clamp the needle cap, and to automatically unscrew the needle from the syringe hub, so that the needle is safely and automatically removed from the syringe hub.

Abstract: In accordance with at least one exemplary embodiment, a surgical instrument comprises a shaft comprising a distal end, a proximal end, and a wall extending from the distal end to the proximal end, the wall surrounding an interior of the shaft. A transmission housing is located at the proximal end of the shaft and the shaft is rotatably coupled to the transmission housing. An actuator in the transmission housing is operably coupled to actuate rotation of the shaft. A port accessible from an exterior of the transmission housing is configured to be fluidically coupled to a fluid supply. A manifold in the transmission housing comprises an inlet and an outlet, the inlet being in fluid communication with the port, the outlet being in fluid communication with the interior of the shaft at the proximal end of the shaft.

Abstract: Systems and methods for a multi-layered peel-away sheath assembly for insertion of a blood pump, the peel-away sheath assembly including a sheath hub and a sheath body having a proximal end that is connected to the sheath hub, and a distal end. The sheath body comprises multiple layers including a reinforcing layer. The reinforcing layer improves flexibility and kink resistance of the assembly. The reinforcing layer can comprise LCP, PEBAX, stainless steel, Nitinol, or Kevlar. The reinforcing layer may be a laser-cut hypotube or a braided or coiled filament. A first layer material and a third layer material are thermoplastics, including PEBAX or TPU. The reinforcing layer has at least one discontinuity, which is aligned with peel-away lines in the sheath body to allow an operator to peel-away the assembly. The peel-away lines are formed of inner notches, outer notches, or both inner notches and outer notches. The sheath hub also includes a discontinuity to allow the sheath hub to peel-away.

Abstract: A wearable drug delivery device that can deliver a liquid drug stored in a container to a patient is provided. The container can be a prefilled cartridge that can be loaded into the drug delivery device by the patient or that can be preloaded within the drug delivery device when provided to the patient. A sealed end of the container is pierced to couple the stored liquid drug to a needle conduit that is coupled to a needle insertion component that provides access to the patient. A drive system of the drug delivery device can expel the liquid drug from the cartridge to the patient through the needle conduit. The drive system can include a spring coupled to a plurality of force transfer elements. The force transfer elements can have a variety of shapes and configurations.

Abstract: An assembly (47) for a medication delivery device (1) has a body (2), a dose setting part (8) configured to be operated by a user for selecting a size of a dose, a piston rod (13) configured to be moved axially without rotating for dispensing a medication, and a drive member (12) being directly coupled to the piston rod (13) for driving the piston rod (13) in a dose dispensing operation, wherein the drive member (12) moves in a proximal direction in a dose setting operation. The medication delivery device (1) into which the assembly is incorporated may be a single-shot, variable-dose injection device, e.g., a syringe.

Abstract: Improvements in fluid volume measurement systems are disclosed for a pneumatically actuated diaphragm pump in general, and a peritoneal dialysis cycler using a pump cassette in particular. Pump fluid volume measurements are based on pressure measurements in a pump control chamber and a reference chamber in a two-chamber model, with different sections being modeled using a combination of adiabatic, isothermal and polytropic processes. Real time or instantaneous fluid flow measurements in a pump chamber of the diaphragm pump are also disclosed, in this case using a one-chamber ideal gas model and using a high speed processor to obtain and process pump control chamber pressures during fluid flow into or out of the pump chamber. Improved heater control circuitry is also disclosed, to provide added or redundant safety measures, or to reduce current leakage from a heater element during pulse width modulation control of the heater element.

Abstract: A drug delivery device configured to provide a dose of a first medicament followed by a dose of a second medicament is disclosed. The device includes a main exterior body and an interior body. The device further includes a dual-chamber reservoir with (i) a first chamber holding the first medicament and (ii) a second chamber holding the second medicament. The device also includes a needle and a plunger. After activation of the device, the plunger is configured to (i) move the dual-chamber reservoir a given distance in a distal direction with respect to the interior body so that a distal end of the needle extends out of the interior body and (ii) after moving the dual-chamber reservoir the given distance, move in the distal direction with respect to the dual-chamber reservoir so as to eject from the needle the first medicament followed by the second medicament.

Abstract: The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose cartridge and permit a user to set a delivery dose. An injector may include a housing, a cartridge containing a medicinal product, the cartridge being retained within the housing, means for selecting a dose of the medicinal product to be expelled, and means for expelling the selected dose of the medicinal product. The housing may be a unitary housing within which the means for selecting the dose and the means for expelling the selected dose are moveably retained. Alternatively, the injector may include a housing, a piston rod, an insert located in the housing and through which the piston rod may rotate, ratchet means, a dose dial sleeve, a drive sleeve, a button located on the drive sleeve and rotatable with respect to the drive sleeve, and clutch means which upon depression of the button prevents rotation between the dose dial sleeve and the drive sleeve.