Abstract: A centrifugal separator includes a rotor arrangement and a drive arrangement. A user of electric energy is arranged in the rotor arrangement. The centrifugal separator includes a rotary transformer, the rotary transformer including a transformer stator and a transformer rotor. The transformer stator and the transformer rotor are arranged adjacent to each other with an airgap therebetween. The transformer rotor includes a secondary coil and is rotatable together with the rotor arrangement. The secondary coil is electrically connected to the user of electric energy arranged in the rotor arrangement for providing the user of electric energy with an electric current. The user of electric energy may be an actuator, and/or a sensor, and/or a control unit.

Abstract: A centrifuge apparatus includes a plurality of modules, each including a rotatable body, housing and flying leads, assembly. The modules can be selectively interconnected to allow adaptation of the processing capacity of the apparatus to process a liquid to remove components therefrom and/or to process a number of different liquids and allow the separation of one or more types of components therefrom simultaneously.

Abstract: A centrifugal separator apparatus for separating components of a fluid stream; the apparatus comprising a support structure and a centrifugal separator unit rotatably mounted on the support structure so as to be rotatable about a rotational axis extending through the centrifugal separator unit; a drive element for driving rotation of the centrifugal separator unit; wherein the centrifugal separator unit comprises a centrifugal separation chamber having an inlet which is connected or connectable to a source of fluid requiring separation, a first outlet for collecting a higher density component of the fluid stream, and a second outlet for collecting a lower density component of the fluid stream; the first outlet being connected or connectable to a first collector for collecting the higher density component and the second outlet being connected or connectable to a second collector for collecting the lower density component; the centrifugal separation chamber comprising a curved or inclined guide surface for g

Abstract: Provided is a centrifuge apparatus for a processing cartridge, including a rotary plate and at least one cartridge holder, and the cartridge holder is rotatable around its centre axis and arranged off-centre the centre axis of the rotary plate and comprises an inner side wall surrounding a through-going passage, wherein the through-going passage is able to accommodate the processing cartridge; and the inner side wall includes a resilient locking assembly for interaction with at least one cooperating first abutting surface on the processing cartridge, such that the processing cartridge may be inserted into the through-going passage and releasably secured by the locking assembly; and at least one stopping element for interaction with at least one cooperating second abutting surface on the processing cartridge, the at least one stopping element being arranged to retain the processing cartridge at a desired vertical level when the cartridge is releasably secured.

Abstract: The present invention relates to a centrifuge rotor with a rotor body and a receptacle arranged centrally therein for receiving a drive head of a drive shaft of a centrifuge which can be rotated about an axis of rotation (R), and sample receptacles for accommodating a plurality of sample containers. A holding crown is arranged on a top side (O) of the rotor body facing away from an insertion side (E) of the drive head, said holding crown having an annular base body, which encloses a central opening, and prongs extending upward away from the top side (O), wherein the holding crown is arranged in such a way that the axis of rotation (R) runs through the central opening. The present invention further relates to a holding crown for use with a centrifuge rotor and having an annular base body enclosing a central opening and prongs emanating from the base body and extending upward, wherein the prongs are offset at least in the region of their free ends by a spacing (A) from an inner edge of the base body.

Abstract: Embodiments relate to systems, chambers, and methods for processing particles by washing, concentrating, and/or treating the particles. Some embodiments provide for the processing of cells that may be in a liquid medium (e.g., a liquid in which the cells were grown) and are processed by being washed and concentrated for later use in research or other therapies.

Abstract: A whole blood separator device has a sleeve. The sleeve has a sleeve body. The sleeve body has an enlarged first proximal end portion and an enlarged second distal end portion and an intermediate cylindrical tube portion connecting the first proximal end portion and the second distal end portion. The sleeve body is configured to fit inside a test tube and receive whole blood which can be separated by centrifugation into a plasma layer in the proximal end portion, a buffy coat layer in the intermediate portion and a red blood cell portion in the distal portion. The whole blood separator device wherein at least the proximal end portion has an open end. Preferably, the distal end portion also has an open end.

Abstract: A centrifuge basket includes a frustum-shaped hollow body defining a pair of opposed ends, being a larger end and a smaller end. The body defines an internal screening surface extending between the ends, the screening surface defining a plurality of apertures arranged to drain liquid from within the body. A plurality of ribs project into an interior of the body from the screening surface, the ribs being arranged in a plurality of annular arrays. The arrays are spaced axially along the screening surface and the ribs of at least one of the arrays are arranged transversely, at a defined included angle, relative to a generatrix line that forms a shape of the screening surface.

Abstract: Embodiments are directed to methods and apparatuses for ensuring that mechanisms that are used to position components of an apheresis machine are not broken as a result of rotation of a centrifuge. In embodiments, a safety mechanism is provided that contacts components of the centrifuge and pushes them into a position to ensure that they do not break when the centrifuge is operated at high rpm.

Abstract: Provided is a method for producing platelets, in which damage to platelets is suppressed compared with a method in which platelets are separated using a filter from a megakaryocyte culture, and then the platelets are concentrated using a hollow fiber membrane and are further washed using the hollow fiber membrane, and purified platelets can be produced in a shorter period of time compared with the time that is taken to perform the above-described method so as to reduce damage to platelets. The method for producing purified platelets of the present invention includes a concentrating step of concentrating a megakaryocyte culture, and a centrifuging step of centrifuging platelets from an obtained concentrate.

Abstract: There is provided a filter sub-assembly that comprises a rotary vessel having a rotor body and a closure member to close an opening of the rotor body. The sub-assembly further comprises a liner that is receivable within the rotor body to line an inner surface thereof. The liner is also fluidly sealable to the closure member by a centrifugal force directed radially outwardly from an axis of rotation, about which the rotary vessel is rotatable. The sub-assembly has particular application in a centrifugal filter of a motor vehicle, for example for cleaning engine oil in an engine lubrication system.

Abstract: A blood washing system (20) having a rotor (22) defining an internal chamber for receiving a multi-component fluid and a skimmer assembly (24) including a moveable buoy (28) having an orifice (32) fluidly connected to an access port for the rotor for selectively withdrawing separated fractions of the multi-component fluid. The multi-component fluid can be fed into the internal chamber before the rotor (22) can be rotated at a first speed to fractionate the multi-component fluid. A brake can be applied to the rotor to slow rotation of the rotor to a slower second speed or stop rotation of the rotor causing the solid and denser fluid fractions to settle on the bottom wall (44) of the rotor (22). The buoy (28) can have a specific gravity corresponding to a selected fraction such that the buoy floats on a surface of the selected fraction, wherein the fractions floating on the selected fraction can be withdrawn through the orifice (32).

Abstract: A rotary vessel for a filter assembly is rotatably mountable in a housing of the filter assembly and has a body having an open end, a cover receivable on the body to close the open end, and a releasable locking device that is manually operable to selectively lock and unlock the cover relative to the body.

Abstract: A blood component sampling cassette which can be more efficiently manufactured at lower cost as compared to a typical cassette, a blood sampling circuit set, and a blood component sampling system. A blood component sampling cassette (22) includes a cassette main body (23) made of a soft material to which heat sterilization is applicable. The cassette main body (23) is provided with a retransfusion line (44). The retransfusion line (44) is provided with a reservoir (47) configured to temporarily store a blood component to be returned to a blood donor. The reservoir (47) is pressed by a retransfusion pump (49) to discharge the blood component from the reservoir (47).

Abstract: A rotor assembly includes a rotor plate to rotate around a first axis; a bucket rotatably attached to the rotor plate and to rotate around a second axis; and a stop plate to rotate around the first axis relative to the rotor plate between an open position and a closed position, when in the closed position, the stop plate is to engage the bucket to fix an angular position of the bucket relative to a plane of rotation of the rotor assembly.

Abstract: A device and method are provided to facilitate the handling of a volume of fluid. The device includes an elongated tube having an open first end and a second end. The tube defines a reservoir for receiving the volume of fluid. A stanchion has a first end received within the reservoir of the tube and a second end projecting from the open end of the elongated tube. In operation, the elongated tube is deposited in a first capsule having fluid therein. The first capsule is centrifuged such that the volume of fluid is received in a reservoir in the tube through the open end. The tube is removed from the first capsule and positioned in a second capsule such that the open end of the tube is spaced from a closed end of the second capsule. The second capsule is centrifuged such that the volume of fluid is expelled from the reservoir of the tube.

Abstract: Mid-procedure termination of a mononuclear cell collection procedure may prevent collection of an amount of red blood cells that is required to harvest a complete mononuclear cell product. Blood separation systems and methods are provided for minimizing the impact of or recovering from mid-procedure termination of such a mononuclear cell collection procedure. According to one approach, blood or separated red blood cells are conveyed into a red blood cell collection container relatively early in the procedure to minimize the impact of a later termination of the procedure. According to another approach, blood and/or separated red blood cells within a fluid processing assembly are redirected through the fluid processing assembly following mid-procedure termination to allow for at least partial mononuclear cell collection.

Abstract: A centrifuge insert is provided which is not only suited for one type of sample container or sample carrier but for at least two geometrically different elements from the group consisting of sample container and sample carrier. This achieves that the same centrifuge insert can be used for different sample containers or sample carriers. This provides space savings, in particular in the lab. Furthermore acquisition cost is reduced, and handling is accelerated by reducing manual complexity which increases lab through put.

Abstract: The present invention relates to a method for separating lymphocytes and/or stem cells from whole blood in an automated blood separation system, wherein the quality of the collected lymphocytes and/or stem cells fractions is increased and the cell collection procedure is further automated by use of an optical sensor comprised in a detector device to measure turbidity and colour in the claimed method and in a cell separator, which can be used to perform the claimed method. The method of the invention is particularly useful to collect lymphocytes and/or stem cells fractions from whole blood, wherein the contamination of the collected cell fractions by platelets, red blood cells and granulocytes is reduced.

Abstract: A method for separating a biological suspension includes dispensing a liquid suspension comprised of cells or microorganisms from a bioreactor or fermenter into a sterile compartment of a first bag assembly, the first bag assembly including a collapsible bag having of one or more sheets of flexible film. The compartment of the first bag assembly is sealed closed. The first bag assembly, either with or without a manifold fluid coupled therewith, is then rotated, such as by using a centrifuge, so that the liquid suspension separates within the compartment into a pellet comprised of the cells or microorganisms and a liquid supernatant.