Patents Examined by Shuyi S Liu
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Patent number: 11660603Abstract: A system and associated method for concentrating and separating components of different densities from fluid containing cells using a centrifuge includes a syringe and a syringe holder, the syringe having a proximal top with a luer port, a sidewall extending from the top forming a syringe tube, and a plunger slidably disposed inside the syringe tube, the plunger forming a sealing engagement with the sidewall, the syringe holder defining a cavity for receiving the syringe, wherein a distal end of the syringe tube is at least partially closed by the syringe holder after the plunger is placed inside the syringe tube.Type: GrantFiled: April 7, 2022Date of Patent: May 30, 2023Assignee: Cervos Medical LLCInventors: Andy H. Levine, John Meade, Neil S. Tischler, Jeffrey R. Chabot, Andrew McGillicuddy, Neil F. Duffy, Jr.
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Patent number: 11660611Abstract: A centrifugal processing unit for directing the movement of substances within a sample processing cartridge, the centrifugal processing unit having a rotor at least one accommodation for receiving the sample processing cartridge, and a rotor drive for rotating the at least one rotor about a respective rotor axis to create the centrifugal force. The centrifugal processing unit has a blocking element allowing the free pivoting motion of the at least one accommodation in a release position when the rotor is rotated in a first direction and preventing the free pivoting motion in a blocking position, when the rotor is rotated in the opposite direction.Type: GrantFiled: May 24, 2018Date of Patent: May 30, 2023Assignee: TECAN TRADING AGInventors: Markus Spiss, Adrian Sager, Fred Schinzel, Markus Wolf
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Patent number: 11660253Abstract: The present invention relates to a platelet rich plasma (PRP) extracting device and extracting method using the same, and more particularly, to a platelet rich plasma (PRP) extracting device capable of quickly and effectively extracting the highly concentrated PRP from centrifuged blood by a simple manipulation.Type: GrantFiled: September 18, 2019Date of Patent: May 30, 2023Assignee: MEDISARANG CO., LTD.Inventors: Seong-il Yeo, Edouard Broussalian
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Patent number: 11661571Abstract: A separator having a vertical rotation axis includes a rotatably mounted drum having a drum interior for centrifugal processing of a liquid. The separator also includes a gas supply line for introducing gas into the liquid, which opens into the drum interior.Type: GrantFiled: August 8, 2019Date of Patent: May 30, 2023Assignee: GEA MECHANICAL EQUIPMENT GmbHInventors: Daniel Bussmann, Thomas Bathelt, Wolf-Dietrich Herberg, Tim Hundertmark, Björn Ströfer
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Patent number: 11660612Abstract: A method for processing a flowable product using a centrifuge includes pretreating the flowable product so that particles in the flowable product are increasingly attracted by electrically charged components, feeding the flowable product into the disc stack, generating an electric charge on the discs of the disc stack, and separating the charged particles from the flowable product within the disc stack under the influence of electrostatic attractive forces and a centrifugal field.Type: GrantFiled: October 23, 2018Date of Patent: May 30, 2023Assignee: GEA Mechanical Equipment GmbHInventors: Wilfried Mackel, Klaus-Peter Eickhoff, Marc Kellens, Knud Schoeneberg, Detlef Ullmann
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Patent number: 11660610Abstract: A turbine having a turbine wheel, as used for example as a drive for active oil separators, and to a liquid separator having such a turbine is described.Type: GrantFiled: September 28, 2017Date of Patent: May 30, 2023Assignee: GRIMALDI DEVELOPMENT ABInventors: Maximilian Birk, Christoph Erdmann, Petr Polednak, Francesco Zitarosa
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Patent number: 11660607Abstract: A separation disc for a centrifugal separator is adapted to be included in a stack of separation discs inside a centrifugal rotor for separating a fluid mixture. The separation disc has a truncated conical shape with an inner surface and an outer surface and a plurality of spacing members extending from at least one of the inner surface and the outer surface. The spot-formed spacing members are for providing interspaces between mutually adjacent separation discs in a stack of separation discs. The separation disc further includes at least one elongated rib extending from the inner surface to a height (h) that is less than the height (H) to which the plurality of spacing members extend. Further, at least one elongated rib extends from first position on the inner surface to a second position on the inner surface.Type: GrantFiled: April 30, 2018Date of Patent: May 30, 2023Assignee: ALFA LAVAL CORPORATE ABInventors: Klas Hilding, Sven-Åke Nilsson, Peter Thorwid
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Patent number: 11660617Abstract: The present invention provides centrifuges (e.g., analytical centrifuges) comprising a cooling assembly having a cooling surface disposed inside the centrifuge chamber and spaced apart from the rotor. The cooling surface disposed inside the centrifuge chamber, spaced apart from the rotor, and configured to exchange heat between the cooling assembly and the rotor, the thermal element thermally coupled to the cooling surface, and configured to control the temperature of the cooling surface.Type: GrantFiled: September 13, 2017Date of Patent: May 30, 2023Assignee: Beckman Coulter, Inc.Inventors: Thomas Ramin, Eric Von Seggern, Brad Hunting, Joe Schorsch
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Patent number: 11660615Abstract: Provided is a centrifugal separation container for separating a material from tissue and body fluids by using a centrifugal force, including: a first container; a second container; a first piston positioned in the inside of the first container and configured to be movable up and down in the inside of the first container; an elastic body positioned below the first piston in the inside of the first container and configured to elastically bias the first piston upward; a first connecting duct having one end connected to the first container and the other end connected to the second container; and a first control valve operating by a centrifugal force and configured to open and close the first connecting duct.Type: GrantFiled: July 18, 2017Date of Patent: May 30, 2023Inventor: Jun Seok Lee
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Patent number: 11660609Abstract: The invention relates to an outlet device (10) of a solid-bowl screw centrifuge for separating a multi-phase material, which outlet device is arranged on an end wall (12) of a centrifuge drum, which rotates about a longitudinal axis, at an outlet opening (20) formed in the end wall, which outlet device comprises a diverting channel (22) for diverting a liquid phase of the material which passes through the outlet opening (20), wherein the diversion relative to the longitudinal axis amounts to an angle (32) between 50° and 90° with respect to the circumferential direction, and which outlet device has an aligned rectilinear weir edge (30) for limiting the emergence of the liquid phase, wherein the angle of the alignment of the weir edge (30) relative to the end wall (12) as viewed from the outlet opening (20) amounts to between 0° relative to the end wall and minus 6° toward the end wall.Type: GrantFiled: December 20, 2018Date of Patent: May 30, 2023Assignee: FLOTTWEG SEInventor: Alfons Kellnberger
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Patent number: 11660616Abstract: A separator includes a preassembled drive and rotation system unit having an outer ring flange portion and a drive frame having an inner ring flange. The outer ring flange portion of the preassembled drive and rotation system unit is vertically connected to the inner ring flange of the drive frame. A rotatable drum is placed onto the preassembled drive and rotation system unit, in the drum at least one paring disk is arranged in a paring chamber, and one or more stacks each having one or more stackable intermediate elements are arranged between the inner ring flange and the outer ring flange portion in order to set an axial relative position at least between the drive frame and the drive and rotation system unit.Type: GrantFiled: June 28, 2018Date of Patent: May 30, 2023Assignee: GEA MECHANICAL EQUIPMENT GMBHInventors: Tim Hundertmark, Johannes Droste, Jürgen Mackel, Eduard Brak
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Patent number: 11660614Abstract: The present disclosure relates to a heavy phase liquid discharge element, a centrifugal separator comprising the element and to a method of separating two liquid phases. The heavy phase liquid discharge element comprises at least one inlet opening on a first side of the heavy phase liquid discharge element, the at least one inlet opening being adapted to face an interior of the centrifugal separator, and at least two separate outlet channels defining an outlet on the second side of the heavy phase liquid discharge element, wherein at least a portion of each of the outlet channels overlaps with the at least one inlet opening, thereby forming a liquid pathway between the at least one inlet opening and the outlet defined by the at least two outlet channels through which the liquid can pass. By this design, pressure losses in the heavy phase liquid outlets can be decreased.Type: GrantFiled: April 29, 2020Date of Patent: May 30, 2023Assignee: ALFA LAVAL CORPORATE ABInventor: Bent Madsen
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Patent number: 11661578Abstract: A centrifugal piston according to an embodiment comprises: a piston body defining a path which extends from the front of the piston to the rear of the piston, and through which substances at the front of the piston can move to the rear of the piston; and a valve disposed on the path and configured to selectively open or block the path, wherein, during centrifugation in which centrifugal force acts on the piston, the substances at the front of the piston are centrifuged while the valve is blocking the path, and, when an external force is applied to the piston while the centrifugal force does not act on the piston, the valve moves freely relative to the piston body, and when the valve opens the path, at least a portion of the substances at the front of the piston can move to the rear of the piston.Type: GrantFiled: September 4, 2018Date of Patent: May 30, 2023Inventor: Jun Seok Lee
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Patent number: 11660608Abstract: An apparatus for facilitating particle separation by density includes a separator having an inner surface surrounding a rotation axis and defining a particle path from an input end to an axially spaced output end. The inner surface includes a plurality of axially spaced dividers having respective inner positions, defining at least in part respective axially spaced retainers for collecting particles during rotation of the separator. The retainers each include at least one fluid inlet for fluidizing particles in the retainer during operation. The dividers include a first pair of adjacent dividers and a second pair of adjacent dividers, the first pair nearer the input end than the second pair, wherein a first divider slope of the first pair is greater than a second divider slope of the second pair and wherein each of the first and second divider slopes is zero or positive. Other systems, apparatuses and methods are disclosed.Type: GrantFiled: April 6, 2022Date of Patent: May 30, 2023Assignee: SEPRO MINERAL SYSTEMS CORP.Inventor: Andrew Gillis
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Patent number: 11660384Abstract: A continuous flow centrifuge bowl includes a rotatable outer body, and a top and bottom core that are rotatable with the outer body. The bottom core has a wall extending proximally from a bottom wall. The proximally extending wall is radially outward from at least a portion of the top core and, together with the top core, defines a primary separation region in which initial separation of the whole blood occurs. The bowl may also have a secondary separation region located between the top core and the outer body, and a rotary seal that couples an inlet port and two outlet ports to the outer body. The inlet port may be connected to an inlet tube that extends distally into a whole blood introduction region. Additionally, one of the outlet ports may be connected to an extraction tube that extends into a region below the bottom core.Type: GrantFiled: September 23, 2020Date of Patent: May 30, 2023Assignee: Haemonetics CorporationInventors: Matthew Murphy, Dominique Uhlmann, Edward Powers, Michael Ragusa, Etienne Pagès
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Patent number: 11648570Abstract: The present invention relates to a fluid treatment chamber with a self-cleaning rotary sight window. The proposed rotary sight window includes a stationary frame (10); a transparent stationary panel (11) attached to the stationary frame by a leak-tight joint (41); a rotary frame (20) connected to the stationary frame (10) by a rotary joint (40); a transparent rotary panel (21) attached to the rotary frame (20) by a joint, the transparent rotary panel (21) being arranged opposite and spaced apart from the transparent stationary panel (11) by an intermediate chamber (1); and a motor (30) connected to the transparent rotary panel (21) or to the rotary frame (20), wherein the joint between the transparent rotary panel (21) and the rotary frame (20) is an interference joint (43) attached by a dimensional interference fit.Type: GrantFiled: March 5, 2018Date of Patent: May 16, 2023Inventor: Marc Riera Domenech
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Patent number: 11549094Abstract: A centrifuge device is provided for the sizing and separation of constituents of a biologic mixture, e.g., adipose tissue. The device provides for the mechanical breaking down of the fibrous structure in the tissue by centrifugation causing the tissue to pass through a mesh element, or a sizing helix, or an extrusion element, whereupon the material is reduced to a slurry. This processed material may then be separated by centrifugation into its constituents, in order to harvest the fraction containing the multipotent cells. These multipotent cells may be utilized for various medical procedures to stimulate healing and tissue regeneration.Type: GrantFiled: June 5, 2020Date of Patent: January 10, 2023Assignee: DSM IP ASSETS B.V.Inventors: John E. Nash, William T. Fisher, Gino Bradica
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Patent number: 11541402Abstract: The invention relates to a separator drum (10) with a hydraulically actuated, axially movable piston slide valve (20) which can seal off a solids space (14) from at least one solids outlet (18), wherein the piston slide valve (20) can be held in its closed position via a closing chamber (30) that can be filled with closing liquid, in particular closing water, wherein the closing chamber (30) is formed between an underside (21) of the piston slide valve (20) and a top side (35) of a drum lower part (15). According to the invention, the closing chamber (30) has a first closing chamber portion (31) near the rotation axis (R) and a second closing chamber portion (32) remote from the rotation axis (R), wherein the first closing chamber portion (31) is formed by two mutually parallel portions (22, 36) of the underside (21) of the piston slide valve (20) and of the top side (35) of the drum lower part (15), and the second closing chamber portion (32) has at least in part a conical cross section.Type: GrantFiled: December 3, 2018Date of Patent: January 3, 2023Assignee: FLOTTWEG SEInventor: Thomas König
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Patent number: 11498082Abstract: Embodiments are directed to methods and apparatuses for ensuring that mechanisms that are used to position components of an apheresis machine are not broken as a result of rotation of a centrifuge. In embodiments, a safety mechanism is provided that contacts components of the centrifuge and pushes them into a position to ensure that they do not break when the centrifuge is operated at high rpm.Type: GrantFiled: March 17, 2020Date of Patent: November 15, 2022Assignee: Terumo BCT, Inc.Inventor: Luke Ryan Noffsinger
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Patent number: 11498083Abstract: A fixed-angle rotor for centrifuges includes stiffening ribs on the lower side of its rotor body. Its rotational energy is comparatively low during operation even at high speeds, whereby safety is noticeably increased without the need for a reinforced armored vessel in the centrifuge that is equipped therewith. At the same time, the drive power required to drive the fixed-angle rotor remains low. The fixed-angle rotor also withstands extreme loads over a long period of time. In addition, the fixed-angle rotor can be manufactured cost-effectively, because no additional components are required; rather, the stiffening ribs can also be manufactured during the manufacture of the rotor body. Finally, very thin rotor shells can also be used, which improves the temperature control of the samples, because the fixed-angle rotor has very good structural stability, especially in the main load directions.Type: GrantFiled: August 15, 2019Date of Patent: November 15, 2022Assignee: Eppendorf AGInventor: Steffen Kühnert