Abstract: The present invention relates to a process for obtaining a furan lipid-rich unsaponifiable material from avocado, which comprises the successive steps (1) of controlled dehydration of fresh avocados or of avocados that have undergone preliminary transformations, (2) of extraction of the oil from dehydrated fruit, (3) of a heat treatment of the extracted oil and of a step of concentration of the unsaponifiable fraction of the oil or alternately, these two operations possibly being carried out successively in this order or in the reverse order, and finally (4) a step of saponification and of extraction of the unsaponifiable material.
Abstract: The invention relates to a novel compound isosquamocin obtained from the plant Annona squamosa; also provides insecticidal compositions containing isosquamocin, squamocin-B (9), squamocin-C (6), squamocin-G (2), squamocin-H (3), squamocin-J (7), squamocin-K (8), squamocin-L (5), squamocin-M (4), squamostatin-A (10), bullatalicin (11), bullatanocin (12) and three unidentified related compounds with retention times 5.88, 14.18 and 45.25 min. in HPLC obtained from the plant Annona squamosa and a process for the preparation of the novel compound and the insecticidal composition.
Type:
Grant
Filed:
March 28, 2002
Date of Patent:
January 31, 2006
Assignee:
Council of Scientific & Industrial Research
Abstract: The invention discloses a pharmaceutical composition for preventing and/or treating peptic ulcer, including American ginseng or the extract thereof, and a method for preparing American ginseng extract, said method including extracting American ginseng with water or ethanol aqueous solution, and then ultrafiltrating, dialyzing, precipitating with ethanol, or performing reverse phase chromatography to obtain various fractions of extract with anti-peptic ulcer effect.
Type:
Grant
Filed:
May 20, 2004
Date of Patent:
January 31, 2006
Assignee:
Medical and Pharmaceutical Industry Technology and Development Center
Abstract: The invention relates to an agent for preventing, improving or treating hypertension, which exhibits a hypotensive effect, inhibits the rise of blood pressure and improves hypertension, and food for preventing or improving hypertension, which does not become a burden in daily intake, has a higher antihypertensive effect and is useful as a diet during treatment for patients of hypertension.
Abstract: A therapeutic or an edible composition comprising at least three of the five herbs selected from Prunus amygdales, Ocimum sanctum, Azadirachta indica, Aegle marelose and Vitus vinefera, is provided for the treatment of hyperglycemia, especially for non-insulin dependent diabetic subjects, and the herbal composition has significantly reduced the blood glucose levels in both diabetic and non-diabetic experimental subjects having elevated blood glucose levels.
Type:
Grant
Filed:
March 19, 2002
Date of Patent:
January 24, 2006
Assignee:
Council of Scientific and Industrial Research
Abstract: L-carnitine, an amino acid, improves sperm quality and motility. Ferulic acid, an antioxidant found in Dong quai, also improves sperm quality. Sperm are highly susceptible to free radical or oxidative damage from environmental toxicants and natural aging. Vitamins C and E, green tea, and selenium are all potent antioxidants that help improve overall reproductive health. Zinc and B vitamins (B6, B 12 and folate) are critical nutrients in male reproductive systems for hormone metabolism, sperm formation and motility.
Abstract: The present invention relates to a pharmaceutical or a food composition for inducing or stimulating secretion of insulin-like growth factor-1. More particularly, the present invention relates to compositions for inducing or stimulating secretion of insulin-like growth factor-1, which comprises (a) a pharmaceutically effective amount of an extract obtained from oriental pharmaceutical selected from the group consisting of Phlomis umbrosa Turez, Cynanchum wilfordii(Max) Hem?, Zingiber officinale Rosc., Platycodi Radix and combination thereof; and (b) a pharmaceutical acceptable carrier.
Abstract: The present invention relates to an agent that suppresses appetite and provides quick energy. According to at least one aspect of the present invention, a lollipop is provided that suppresses appetite and provides quick energy. The lollipop is made from a premixed herbal formula that is combined with a hard candy confection base. The herbal premixed formula includes the following active ingredients: Guarana PE 22%; CitriMax®; and L-Tyrosine. The herbal premix formula can also include Vitamin B6; and Vitamin B12 Cyanacobalamin. The premixed formula is added to a candy base that may include corn syrup, Maltodextrin, sugar, natural color and natural flavorings.
Abstract: Compositions comprising an effective amount of a curcuminoid species and an effective amount of a diterpene lactone species, a triterpene species or derivatives thereof that have a synergistic effect on specific inhibition of inducible COX-2 activity and have minimal effect on COX-1 activity are disclosed. Methods of using the compositions for providing synergistic anti-inflammatory effects are also disclosed.
Type:
Grant
Filed:
July 16, 2002
Date of Patent:
December 27, 2005
Assignee:
Metaproteomics, LLC
Inventors:
John G. Babish, Terrence Howell, Linda Pacioretty
Abstract: The invention relates to a new use of a non-alkaloid compound that is plant derived glycoside ‘glycyrrhizin’ as a highly potent bio-enhancer of activity and availability of antibiotics and other drugs including anti-infective and anticancer agents. The molecule of invention facilitates the absorption/uptake of antibiotics and other molecules across the cell membrane in plant and animal cells as well as Gram-positive and Gram-negative bacteria and therefore can be used as a drug facilitator or bioenhancer molecule to increase the affectivity of drugs and nutraceutical agents. The compound having no antimicrobial or cytotoxic activity of its own, is a safe candidate to reduce the drug dosage towards circumventing the problem of drug resistance and the other side effects in anti-infective and anti-cancer therapies.
Type:
Grant
Filed:
September 5, 2000
Date of Patent:
December 27, 2005
Assignee:
Council of Scientific and Industrial Research
Abstract: The invention is a beverage involving an ingestible fluid and a dosage amount of an ingestible composition for treating an inflammatory tissue in a mammal, involving the inflammatory tissue selected from the group comprising underperfused tissue, inflamed joints, inflamed muscles, wherein the dosage amount has a glucose ingredient, such as glucosamine sulfate, glucosamine hydrochloride, n-acetyl glucosamine, and combinations thereof; a chondroitin component, such as chondroitin sulfate, chondroitin hydrochloride, and combinations thereof; a member of the family of araliaceae for buffering the ingestion of the glucose ingredient, such as American ginseng, Siberian ginseng, panax ginseng, and combinations thereof; a calcium containing component; and a sulfonate having at least one methyl group ingesting the beverage.
Abstract: Described is a composition for the prevention and treatment of symptoms associated with ethyl alcohol consumption. The composition comprises silymarin, salicin, at least one B vitamin, magnesium, molybdenum and manganese. Treatment of symptoms associated with the consumption of ethyl alcohol involves ingesting the described composition prior to, during, or after the consumption of the alcohol.
Abstract: The invention discloses a pharmaceutical composition for preventing and/or treating peptic ulcer, including American ginseng or the extract thereof, and a method for preparing American ginseng extract, said method including extracting American ginseng with water or ethanol aqueous solution, and then ultrafiltrating, dialyzing, precipitating with ethanol, or performing reverse phase chromatography to obtain various fractions of extract with anti-peptic ulcer effect.
Type:
Grant
Filed:
March 9, 2000
Date of Patent:
November 8, 2005
Assignee:
Pharmaceutical Industry Technology and Development Center
Abstract: The present invention discloses an anti-obesity agent comprising: D-cysteinolic acid represented by Formula I, as an active ingredient: Formula I:
Abstract: The present invention provides a composition containing an extract from Wisteria floribunda, Myristica fragrans, Punica granatum, Trapa bispinosa or a derivative thereof, Coix lachiryma-jobi, Elfvingia applanata and Ganoderma lucidum or a derivative thereof (optionally further containing Panax ginseng or Panax japonicus), which has a superior antiviral activity, a superior peripheral blood flow-improving activity and a superior hair growth-stimulating activity, and a production method thereof.
Type:
Grant
Filed:
July 24, 2002
Date of Patent:
October 11, 2005
Assignee:
Nitto Denko Corporation
Inventors:
Hozumi Tanaka, Ken Hibino, Yasuyo Hijikata
Abstract: This invention refers to the preparation for elimination of neuropathies in diabetes. The preparation contains a combination of minerals and plant extracts. By its ionic exchange, the invention reduces considerably the process of apoptosis of nerve-cells, eliminates the process of activation of the immunologic system, and stops the immunologic reaction of auto-destruction of nerve-cells. Depositing of immunoglobulin on axons is absent, and neuropathic pain disappears. Furthermore, the preparation reduces the activity of free radicals, improves the regulation of glycemia and improves the recovery of axons which are already damaged.
Type:
Grant
Filed:
May 4, 2001
Date of Patent:
October 11, 2005
Inventors:
Robert Basic, Milivoj Slijepcevic, Mirko Hadzija, Marijana Hadzija
Abstract: A pharmaceutical agent for treating an amyloid disease such as Alzheimer's Disease that includes a therapeutically effective amount of an extract obtained from the inner bark or root tissue of a plant of the genus Uncaria, species tomentosa, wherein the weight percentage of plant extract in the agent is in the range of from about 70% to about 95%.
Abstract: To conduct a search for natural drugs and their formulae derived from natural substances that hardly cause side effects and drug tolerance, based on quite a new idea having departed from conventional drugs such as Chinese galenicals, Chinese medicine formulae, etc. and to develop a composition that has an anticancer activity and is selectively cytotoxic to cancer cells. A composition having an anticancer effect is obtained, which comprises therapeutically effective amounts of a dry product of Angelica keiskei and a dry product of Theaceae Camellia. Also, a composition having an anticancer activity is obtained, which comprises therapeutically effective amounts of a dry product of Angelica keiskei and/or a dry product of Theaceae Camellia together with a dry product of defatted whole egg of eggs of a fowl bred by feeding a feed having blended therein an additive comprising a dry product of Angelica keiskei, a dry product of brown algae, and optionally a dry product of Theaceae Camellia.
Abstract: This invention provides carbohydrate absorption inhibitor derived from evening primrose seed which is significantly effective to prevent and cure diabetes mellitus and prevent obesity, and the manufacturing method of the same. Carbohydrate absorption inhibitor in this invention is characterized that the effective component is an alcohol extract of evening primrose seed. The aforementioned evening primrose seed is preferably a defatted evening primrose seed. Extracting solvent of the aforementioned evening primrose seed is preferably ethanol, or preferably a 70 to 85% (v/v) aqueous ethanol. Also, this invention is characterized that the carbohydrate absorption inhibitor is an effective component of polyphenol derived from evening primrose seed. The polyphenol is preferably one or more substances selected from among gallic acid, ellagic acid, catechin, pentagalloylglucose, procyanidin, and proantocyanidin.
Abstract: The present invention provides a group of tobacco alkaloids, tobacco extract, Yerbamaté extract, and an extract of chewing gum and lozenges which are modulators of monoamine oxidase (MAO) activity (i.e., compounds and substances which inhibit MAO enzyme and prevent its biological activity). The MAO inhibitors of the present invention can cause an increase in the level of norepinephrine, dopamine, and serotonin in the brain and other tissues, and thus can cause a wide variety of pharmacological effects mediated by their effects on these compounds. The MAO inhibitors of the present invention are useful for a variety of therapeutic applications, such as the treatment of depression, disorders of attention and focus, mood and emotional disorders, Parkinson's disease, extrapyramidal disorders, hypertension, substance abuse, smoking substitution, anti-depression therapy, eating disorders, withdrawal syndromes, and the cessation of smoking.
Type:
Grant
Filed:
March 26, 2003
Date of Patent:
August 16, 2005
Assignee:
Regent Court Technologies, LLC
Inventors:
Jonnie R. Williams, Robert J. DeLorenzo, Harold R. Burton