Patents Examined by Vivian Garner
  • Naphthoquinone derivatives
    Patent number: 4909966
    Abstract: New chemical compounds are derivatives of certain substituted 1,4-napthoquinones in which the keto oxygens at the 4-positions have been replaced by certain cyanoalkoxycarbonylmethylene groups. The new compounds have the structure ##STR1## wherein: J is alkyl having 1 to 6 carbon atoms, andR is normal alkyl having 1 to 6 carbon atoms.The compounds are useful as electron-transport agents in electrophotographic elements.
    Type: Grant
    Filed: December 21, 1988
    Date of Patent: March 20, 1990
    Assignee: Eastman Kodak Company
    Inventors: Teh-Ming Kung, William B. Vreeland, Ralph H. Young
  • Removal of organic iodine compounds from carbonylation products of methanol methyl acetate and dimethyl ether
    Patent number: 4908477
    Abstract: Organic iodine compounds are separated from carbonylation products of methanol, methyl acetate and dimethyl ether and from mixtures of such carbonylation products by a process wherein the iodine compounds are removed by liquid phase extraction with a non-aromatic hydrocarbon.
    Type: Grant
    Filed: March 9, 1987
    Date of Patent: March 13, 1990
    Assignee: BASF Aktiengesellschaft
    Inventors: Horst Hartmann, Waldhelm Hochstein, Gerd Kaibel, Franz-Josef Mueller
  • Fluoro-sulfones
    Patent number: 4906658
    Abstract: Compounds of Formula I ##STR1## the pharmaceutically acceptable salts, and the gamma-lactone form thereof are described. They are antagonists of leukotrienes and SRS-A.
    Type: Grant
    Filed: April 21, 1987
    Date of Patent: March 6, 1990
    Assignee: Merck Frosst Canada, Inc.
    Inventors: Haydn W. R. Williams, Robert N. Young
  • Process for producing 2-methyl-1,4-naphthoquinone
    Patent number: 4906411
    Abstract: An improved process for producing 2-methyl-1,4-naphthoquinone with a high yield comprising reaction of a 1-lower-alkoxy-2-methyl naphthalene with hydrogen peroxide in the presence of a hexacyanoferric acid or a salt thereof as catalyst. This process does not employ hazardous chromium compounds unlike conventional methods.
    Type: Grant
    Filed: May 19, 1987
    Date of Patent: March 6, 1990
    Assignee: Eisai Chemical Co., Ltd.
    Inventors: Atsushi Shinnaka, Yukio Narabu
  • Chlorinated .beta.-ketoesters
    Patent number: 4906414
    Abstract: New chlorinated .beta.-ketoesters of the formula: ##STR1## wherein R represents alkyl of 1 through 6 carbon atoms or alkenyl of 2 through 6 carbon atoms, and R.sub.1 represents alkyl of 1 through 4 carbon atoms, their preparation and their use for the preparation of ethylenic ketones of the formula: ##STR2## wherein R is as hereinbefore defined.
    Type: Grant
    Filed: January 25, 1989
    Date of Patent: March 6, 1990
    Assignee: Rhone-Poulenc Sante
    Inventor: Didier Morel
  • Bischoloroformate preparation method with phosgene removal and monochloroformate conversion
    Patent number: 4904810
    Abstract: Aqueous bischloroformates are prepared by the reaction of a dihydroxyaromatic compound (e.g., bisphenol A) with phosgene in a substantially inert organic liquid (e.g., methylene chloride) and in the presence of an aqueous alkali metal or alkaline earth metal base, at a pH below about 8. After all solid dihydroxyaromatic compound has been consumed, the pH is raised to a higher value in the range of about 7-12, preferably 9-11, and maintained in said range until a major proportion of the unreacted phosgene has been hydrolyzed. At the same time, any monochloroformate in the product may be converted to bischloroformate.
    Type: Grant
    Filed: July 25, 1988
    Date of Patent: February 27, 1990
    Assignee: General Electric Company
    Inventors: Daniel J. Brunelle, Thomas G. Shannon
  • Recovery of aqueous glyoxylic acid solutions
    Patent number: 4902828
    Abstract: Aqueous glyoxylic acid solutions, essentially free of other acids, are recovered from aqueous solutions which still contain other acids, by a method in which the aqueous solution is mixed with an organic nitrogen compound at as high as 50.degree. C., the phases are separated, and the glyoxylic acid is extracted from the organic phase with water, at a higher temperature.
    Type: Grant
    Filed: October 18, 1984
    Date of Patent: February 20, 1990
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerhard Wickenhaeuser, Bernd Heida, Fritz Graf, Leopold Hupfer
  • Process for the preparation of adipic acid
    Patent number: 4902827
    Abstract: Disclosed is an improved process for the preparation of adipic acid by the air oxidation of cyclohexane in the presence of acetic acid and a catalyst system comprising cobalt and zirconium and/or hafnium.
    Type: Grant
    Filed: May 3, 1988
    Date of Patent: February 20, 1990
    Assignee: Eastman Kodak Company
    Inventors: Guy R. Steinmetz, Norma L. Lafferty, Charles E. Sumner, Jr.
  • Quinone intermediates for asymmetric synthesis of natural vitamin E
    Patent number: 4900476
    Abstract: An asymmetric synthesis for Vitamin E in an optically active pure form for 4-(2,5-diloweralkanoyloxy)-3,4,6-trimethylphenyl-butan-2-one and intermediates therein.
    Type: Grant
    Filed: January 30, 1989
    Date of Patent: February 13, 1990
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Ka-kong Chan, Gabriel G. Saucy
  • Process for producing fluorinated esters
    Patent number: 4898970
    Abstract: This invention relates to a process for producing a fluorinated ester containing a trifluoromethyl group by esterification in the presence of .gamma.-butyrolactone as a solvent, and more particularly a process or producing a fluorinated ester containing a trifluoromethyl group which is useful as a raw material of various fluorine containing compound.
    Type: Grant
    Filed: February 1, 1983
    Date of Patent: February 6, 1990
    Assignees: Onoda Cement Co., Ltd., Tosoh Corporation
    Inventors: Eiji Ogura, Kunihiro Mito, Shoji Arai
  • Benzoquinone derivatives, their production and use
    Patent number: 4897420
    Abstract: Compounds of the formula: ##STR1## wherein l is an integer of 0 to 18, X is hydrogen, an alkyl having 1 to 4 carbon atoms or a carboxylic acyl having 2 to 4 carbon atoms and Y is a phenylene, a cycloalkylene having 3 to 7 carbon atoms or a group of the formula: ##STR2## in which m is an integer of 0 to 3, and R.sub.1 and R.sub.2 each is an alkyl having 1 to 4 carbon atoms, are novel compounds, possess circulatory disturbance-improving activity and inhibitory activity of the generation and release of SRS-A, and used for prophylactic or therapy of ischemic diseases such as cerebral apoplexy or allergic diseases.
    Type: Grant
    Filed: December 5, 1988
    Date of Patent: January 30, 1990
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Masazumi Watanabe, Isuke Imada
  • Homologation of carbonyloxy containing compounds
    Patent number: 4897473
    Abstract: This invention produces higher homologs, i.e., differing by at least a --CH.sub.2 -unit, of carbonyloxy-containing compounds by treating the carbonyloxy-containing compounds with carbon monoxide and hydrogen in the presence of a ruthenium-containing compound, a proton donor, an iodide promoter, and optionally, a manganese-containing compound.
    Type: Grant
    Filed: May 1, 1981
    Date of Patent: January 30, 1990
    Assignee: Union Carbide Chemicals and Plastics Company Inc.
    Inventor: Bernard D. Dombek
  • Calcium salt of valproic acid
    Patent number: 4895873
    Abstract: The invention relates to a new crystalline calcium salt of valproic acid, in which per molecule 5 valproic acid radicals are associated with one calcium ion. The salt is non-hygroscopic and has superior galenic characteristics as active agent in pharmaceutical preparations, particularly for oral application.The calcium salt is useful for the treatment of epilepsy and febrile convulsions.
    Type: Grant
    Filed: March 16, 1988
    Date of Patent: January 23, 1990
    Assignee: Desitin Arzenimittel GmbH
    Inventor: Helmut Schafer
  • Process for producing fatty acids and their ester derivatives
    Patent number: 4894188
    Abstract: Fatty acid and their derivatives are simply produced by reacting an olefin, carbon monoxide and water or reacting an alcohol or its derivative and carbon monoxide in the presence of a hydrogen fluoride catalyst and thermally decomposing the resulting reaction product in the presence of a lower hydrocarbon or a lower halogenated hydrocarbon.
    Type: Grant
    Filed: February 13, 1985
    Date of Patent: January 16, 1990
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Takehiko Takahashi, Makoto Takagawa, Tomiyoshi Furuta, Toshio Hidaka, Kazuo Takada
  • Process for regenerating a carbonylation catalyst solution to remove corrosion metals and carbonylation of methanol to acetic acid
    Patent number: 4894477
    Abstract: A process for treating carbonylation catalyst solutions which contain a rhodium component and a lithium component to remove metallic corrosion products comprises contacting the catalyst solution with a cation exchange resin in the lithium form.
    Type: Grant
    Filed: October 14, 1986
    Date of Patent: January 16, 1990
    Assignee: Hoechst Celanese Corporation
    Inventors: Mark O. Scates, G. P. Torrence, Ronny G. Wood
  • Alpha-acyloxyketone derivatives
    Patent number: 4894475
    Abstract: Disclosed are alpha-acyloxyketone derivatives which are useful as intermediates for production of N-cyano-N'-methyl-N"-[2-{(5-methyl-1H-imidazol-4-yl)methylthio}ethyl]guani dine (common name: Cimetidine; Cimetidine applies hereinafter) and Cimetidine-related compounds which have an action of controlling secretion of gastric acid and are useful as a drug for treating gastric ulcer.
    Type: Grant
    Filed: December 28, 1987
    Date of Patent: January 16, 1990
    Assignee: Mitsui Petrochemical Industries, Ltd.
    Inventors: Hiroaki Tan, Koji Kato, Junichi Imuta, Noriaki Kihara
  • Process for synthesis of amidoacids using a cobalt catalyst and a bidental phosphine ligand
    Patent number: 4892687
    Abstract: A process is disclosed for producing N-acetyl-aminoacid which comprises reacting a feedstock from the group consisting of simple olefins, acetamide and synthesis gas with a catalyst comprising a cobalt-containing compound promoted by a bidental-phosphine ligand in a solvent at a pressure of 500 psi or greater and a temperature of 50.degree. C. or greater. The presence of the ligand increases both reaction rate and cobalt catalyst stability.
    Type: Grant
    Filed: October 8, 1986
    Date of Patent: January 9, 1990
    Assignee: Texaco Inc.
    Inventor: Jiang-Jen Lin
  • Staged aromatics oxidation in aqueous systems
    Patent number: 4892970
    Abstract: Improved acid yield and product quality are realized in the oxidation of aromatic hydrocarbons in a two-stage process, employing an aqueous solvent system and an increased proportion of bromine, and, optionally, of catalytic metals, in the second stage.
    Type: Grant
    Filed: December 30, 1985
    Date of Patent: January 9, 1990
    Assignee: Amoco Corporation
    Inventors: Neal R. Nowicki, James D. Lowry, Jr.
  • Acetoacetic acid ester derivatives for the manufacture of .alpha.-hydroxycarbonyl compounds
    Patent number: 4892966
    Abstract: The invention is concerned with a novel process for the manufacture of compounds of the formula ##STR1## wherein R.sup.1 signifies C.sub.1-5 -alkyl, especially methyl, ethyl, propyl or isopropyl, and the radicals R.sup.2 each independently represent hydrogen or C.sub.1-5 -alkyl, especially hydrogen or methyl, ethyl, propyl or isopropyl.The process is characterized in that a compound of the formula ##STR2## wherein R stands for C.sub.1-4 -alkoxy, chlorine, bromine or C.sub.1-4 -alkanoyloxy, R.sup.1 and R.sup.2 have the above significance and R.sup.3 represents C.sub.1-4 -alkyl.is hydrolyzed and subjected to an aldol condensation and, where R=C.sub.1-4 -alkoxy, the reaction product is subsequently subjected to an acid treatment.The compounds I are for the most part known flavoring substances.
    Type: Grant
    Filed: July 16, 1987
    Date of Patent: January 9, 1990
    Assignee: Givaudan Corporation
    Inventor: Hans J. Wild
  • Process for the production of pimelic acid
    Patent number: 4888443
    Abstract: A process for the production of pimelic acid comprising reacting .epsilon.-caprolactone with carbon monoxide and water in the presence of a carbonylation catalyst, such as a Group VIII metal and hydrogen halide.
    Type: Grant
    Filed: October 9, 1984
    Date of Patent: December 19, 1989
    Assignee: National Distillers and Chemical Corporation
    Inventors: Jawad H. Murib, John H. Kahn