Patents by Inventor Aled Edwards

Aled Edwards has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystal structures of YHHF polypeptides
    Publication number: 20070010949
    Abstract: The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified protein comprising the amino acid sequence set forth in SEQ ID NO: 4. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention.
    Type: Application
    Filed: June 30, 2005
    Publication date: January 11, 2007
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Matthew Kimber
  • Crystal structures of aspartate semialdehyde dehydrogenases
    Publication number: 20070004020
    Abstract: The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified protein comprising the amino acid sequence set forth in SEQ ID NO: 4. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention.
    Type: Application
    Filed: June 30, 2005
    Publication date: January 4, 2007
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Matthew Kimber, Robert Lam
  • Method and system for performing a hash transformation to generate a hash pointer for an address input by using rotation
    Patent number: 7126948
    Abstract: A method for performing a hash transformation in a network device to generate a hash pointer for an address input by using rotation. The method includes to step of receiving an address input. Rotated copies of the address input are subsequently logically combined in accordance with a key to generate a hashing result corresponding to the address input. The hash result is subsequently output.
    Type: Grant
    Filed: March 21, 2002
    Date of Patent: October 24, 2006
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Mark Gooch, Aled Edwards
  • Systems and methods for identifying diagnostic indicators
    Publication number: 20060177837
    Abstract: Systems and methods are provided for predicting patient response to a therapy regimen for a liver disease or a disease that is treatable with an immunomodulatory disease therapy using gene expression classifiers. Systems and methods for screening for modulators of target gene expression are also provided. Systems and methods for developing therapeutics against one or more of the proteins coded for by genes of the present invention are also provided. Systems and methods for predicting a patient response to a regimen of pegylated interferon alpha and ribavirin in a therapy for hepatitis C viral infection are also provided.
    Type: Application
    Filed: August 15, 2005
    Publication date: August 10, 2006
    Inventors: Ivan Borozan, Limin Chen, Aled Edwards, Elizabeth Heathcote, Ian McGilvray
  • Essential novel bacterial polypeptides
    Publication number: 20060104989
    Abstract: The present invention relates to polypeptide targets for pathogenic bacteria. The invention also provides biochemical and biophysical characteristics of those polypeptides.
    Type: Application
    Filed: May 5, 2005
    Publication date: May 18, 2006
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi
  • Crystal structures of NH3-dependent NAD synthetases
    Publication number: 20060079669
    Abstract: The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified protein comprising the amino acid sequence set forth in SEQ ID NO: 4. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention.
    Type: Application
    Filed: June 30, 2005
    Publication date: April 13, 2006
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Matthew Kimber, Robert Lam
  • Novel purified polypeptides from haemophilus influenzae
    Publication number: 20060078922
    Abstract: The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified protein comprising the amino acid sequence set forth in SEQ ID NO: 4. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention.
    Type: Application
    Filed: September 12, 2005
    Publication date: April 13, 2006
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Robert Lam
  • Novel purified polypeptides from Enterococcus faecalis
    Publication number: 20060078977
    Abstract: The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified protein comprising the amino acid sequence set forth in SEQ ID NO: 4. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention.
    Type: Application
    Filed: June 27, 2005
    Publication date: April 13, 2006
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Teresa Clarke
  • Crystal structures of bacterial thymidylate kinases
    Publication number: 20060078976
    Abstract: The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified protein comprising the amino acid sequence set forth in SEQ ID NO: 8. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention.
    Type: Application
    Filed: May 5, 2005
    Publication date: April 13, 2006
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Teresa Clarke, Matthew Kimber
  • Novel purified hydroxymethylglutaryl-CoA reductases and structures thereof
    Publication number: 20060078974
    Abstract: The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified protein comprising the amino acid sequence set forth in SEQ ID NO: 4. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention.
    Type: Application
    Filed: September 16, 2005
    Publication date: April 13, 2006
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Klaus Fiebig, Robert Lam
  • Crystal structures of bacterial guanylate kinases
    Publication number: 20060073581
    Abstract: The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified protein comprising the amino acid sequence set forth in SEQ ID NO: 4. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention.
    Type: Application
    Filed: May 5, 2005
    Publication date: April 6, 2006
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Nicole Brufatto, Teresa Clarke
  • Novel purified polypeptides from enterococcus faecalis
    Publication number: 20060003432
    Abstract: The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified protein comprising the amino acid sequence set forth in SEQ ID NO: 4. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention.
    Type: Application
    Filed: January 31, 2005
    Publication date: January 5, 2006
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Bryan Beattie, Teresa Clarke, Matthew Kimber
  • Novel purified polypeptides from Pseudomonas aeruginosa
    Publication number: 20050245728
    Abstract: The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified protein comprising the amino acid sequence set forth in SEQ ID NO: 4. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention.
    Type: Application
    Filed: October 18, 2004
    Publication date: November 3, 2005
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Matthew Kimber, Francois Vallee
  • Peptidyl-tRNA hydrolase of Enterococcus faecalis
    Publication number: 20050239186
    Abstract: The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified protein comprising the amino acid sequence set forth in SEQ ID NO: 4. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention.
    Type: Application
    Filed: January 31, 2005
    Publication date: October 27, 2005
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Bryan Beattie, Matthew Kimber
  • Novel purified polypeptides from pseudomonas aeruginosa
    Publication number: 20050221462
    Abstract: The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified protein comprising the amino acid sequence set forth in SEQ ID NO: 4. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention.
    Type: Application
    Filed: October 14, 2004
    Publication date: October 6, 2005
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Megan Domagala, Matthew Kimber, Francois Vallee
  • Novel purified polypeptides from streptococcus pneumoniae
    Publication number: 20050214918
    Abstract: The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified protein comprising the amino acid sequence set forth in SEQ ID NO: 4. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention.
    Type: Application
    Filed: October 8, 2004
    Publication date: September 29, 2005
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Matthew Kimber
  • Novel purified polypeptides from bacteria
    Publication number: 20050214773
    Abstract: The present invention relates to polypeptide targets for pathogenic bacteria. The invention also provides biochemical and biophysical characteristics of those polypeptides.
    Type: Application
    Filed: March 22, 2004
    Publication date: September 29, 2005
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Muhammad Alam, Megan Domagala, Simon Houston, Robert Lam, Qin Li, Kathleen Nethery-Brokx, Ivy Ng, Benjamin Pinder, Cristina Viola, Olga Wrezel, Dhushy Kanagarajah, Kamran Mansoury, Sasha Necakov, Francois Vallee, Merry-Lynn McDonald
  • Novel purified polypeptides from Streptococcus pneumoniae
    Publication number: 20050187718
    Abstract: The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified protein comprising the amino acid sequence set forth in SEQ ID NO: 4. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention.
    Type: Application
    Filed: August 20, 2004
    Publication date: August 25, 2005
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Teresa Clarke, Matthew Kimber, Vivek Sharma, Simon Houston, Kamran Mansoury
  • Novel purified polypeptides from bacteria
    Publication number: 20050181388
    Abstract: The present invention relates to polypeptide targets for pathogenic bacteria. The invention also provides biochemical and biophysical characteristics of those polypeptides.
    Type: Application
    Filed: October 4, 2004
    Publication date: August 18, 2005
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Muhammad Alam, Cheryl Arrowsmith, Donald Awrey, Bryan Beattie, Kristina Buzadzija, Veronica Canadien, Megan Domagala, Simon Houston, Dhushy Kanagarajah, Qin Li, Kamran Mansoury, Merry-Lynn McDonald, Kathleen Nethery-Brokx, Ivy Ng, Hui Ouyang, Benjamin Pinder, Dawn Richards, Matthew Tai, Rosanne Thalakada, Francois Vallee, Cristina Virag
  • Novel purified polypeptides from bacteria
    Publication number: 20050181464
    Abstract: The present invention relates to polypeptide targets for pathogenic bacteria. The invention also provides biochemical and biophysical characteristics of those polypeptides.
    Type: Application
    Filed: September 29, 2004
    Publication date: August 18, 2005
    Applicant: Affinium Pharmaceuticals, Inc.
    Inventors: Aled Edwards, Akil Dharamsi, Masoud Vedadi, Muhammad Alam, Cheryl Arrowsmith, Donald Awrey, Bryan Beattie, Kristina Buzadzija, Teresa Clarke, Megan Domagala, Simon Houston, Dhushy Kanagarajah, Qin Li, Kamran Mansoury, Merry-Lynn McDonald, Kathleen Nethery-Brokx, Ivy Ng, Hui Ouyang, Dawn Richards, Francois Vallee, Cristina Virag