Abstract: Systems and methods are described for providing previews of deployment of data stream processing instructions sets, sometimes called pipelines, to a stream data processing system. Rather than deploying such an instruction set, which may cause detrimental side effects, previews can be facilitated by conversion of a data stream processing instructions set to a batch query that is applied to an existing data set. An output of the batch query can then be provided to an end user as a preview of output of the data stream processing instructions set, when implemented.

Abstract: Provided are compositions related to HSD17B13 variants, including nucleic acid molecules and polypeptides related to variants of HSD17B13, and cells comprising those nucleic acid molecules and polypeptides. Also provided are methods related to HSD17B13 variants. Such methods include methods for detecting the presence of the HSD17B13 rs72613567 variant in a biological sample comprising genomic DNA, for detecting the presence or levels of any one of variant HSD17B13 Transcripts C, D, E, F, G, and H, and particularly D, in a biological sample comprising mRNA or cDNA, or for detecting the presence or levels of any one of variant HSD17B13 protein Isoforms C, D, E, F, G, or H, and particularly D, in a biological sample comprising protein. Also provided are methods for determining a subject's susceptibility to developing a liver disease or of diagnosing a subject with liver disease.

Abstract: The present invention relates to a nanoparticulate composition comprising nanoparticles formed from an amphipathic block copolymer comprising a hydrophilic block and a hydrophobic block, where the nanoparticles are provided in the form of micelles, cylindrical worm structures or vesicles and the size of the nanoparticles is from 25 to 500 nm, wherein: the composition is substantially free of heavy metals and compounds comprising sulfur. Also disclosed herein is a method of forming said nanoparticulate composition by polymerization induced self-assembly (PISA) via non-transition-metal catalysed controlled radical polymerization (NTMC-CRP).

Abstract: Systems, method, and devices provide for recovery from backhaul failures for Integrated Access and Backhaul (IAB) communication systems with multi-hop routing.

Abstract: Implementations are described herein for learning mappings between a domain specific language (DSL) and images, and leveraging those mappings for various purposes. In various implementations, a method for using a DSL to generate training data may include processing data indicative of ground truth image(s) depicting a real plant using a trained image-to-DSL machine learning (ML) model to generate a first expression in the DSL that describes structure of the real plant. The first expression may include a plurality of parameters, and may be processed to programmatically generate a plurality of synthetic DSL expressions. Each respective synthetic DSL expression may describe structure of a respective synthetic plant for which parameter(s) have been altered from the first expression. The synthetic DSL expressions may be processed using a renderer to create three-dimensional (3D) synthetic plant models. Two-dimensional (2D) synthetic images may be generated that depict the 3D synthetic plant models in an area.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for estimating a 3-D pose of an object of interest from image and point cloud data. In one aspect, a method includes obtaining an image of an environment; obtaining a point cloud of a three-dimensional region of the environment; generating a fused representation of the image and the point cloud; and processing the fused representation using a pose estimation neural network and in accordance with current values of a plurality of pose estimation network parameters to generate a pose estimation network output that specifies, for each of multiple keypoints, a respective estimated position in the three-dimensional region of the environment.

Abstract: For example, an apparatus may include a segment parser to parse scrambled data bits of a PPDU into a first plurality of data bits and a second plurality of data bits, the PPDU to be transmitted in an OFDM transmission over an aggregated bandwidth comprising a first channel in a first frequency band and a second channel in a second frequency band; a first baseband processing block to encode and modulate the first plurality of data bits according to a first OFDM MCS for transmission over the first channel in the first frequency band; and a second baseband block to encode and modulate the second plurality of data bits according to a second OFDM MCS for transmission over the second channel in the second frequency band.

Abstract: A lab automation system receives an instruction from a user to perform a protocol within a lab via an interface including a graphical representation of the lab. The lab includes a robot and set of equipment rendered within the graphical representation of the lab. The lab automation system identifies an ambiguous term of the instruction and pieces of equipment corresponding to the ambiguous term and modifies the interface to include a predictive text interface element listing the pieces of equipment. Upon a mouseover of a listed piece of equipment within the predictive text interface element, the lab automation system modifies the graphical representation of the lab to highlight the listed piece of equipment corresponding to the mouseover. Upon a selection of the listed piece of equipment within the predictive text interface element, the lab automation system modifies the instruction to include the listed piece of equipment.

Abstract: The present disclosure provides systems and methods for applying anti-tachycardia pacing (ATP) using subcutaneous implantable cardioverter-defibrillators (SICDs). An SICD implantable in a subject includes a case including a controller, and at least one conductive lead extending from the case. The at least one conductive lead includes a plurality of coil electrodes, wherein the SICD is configured, via the controller, to apply anti-tachycardia pacing (ATP) to the subject using the at least one conductive lead.

Abstract: Various embodiments of a dural elevating and cutting apparatus and methods of use are disclosed herein.

Abstract: Systems and methods are provided for vector-quantized image modeling using vision transformers and improved codebook handling. In particular, the present disclosure provides a Vector-quantized Image Modeling (VIM) approach that involves pretraining a machine learning model (e.g., Transformer model) to predict rasterized image tokens autoregressively. The discrete image tokens can be encoded from a learned Vision-Transformer-based VQGAN (example implementations of which can be referred to as ViT-VQGAN). The present disclosure proposes multiple improvements over vanilla VQGAN from architecture to codebook learning, yielding better efficiency and reconstruction fidelity. The improved ViT-VQGAN further improves vector-quantized image modeling tasks, including unconditional image generation, conditioned image generation (e.g., class-conditioned image generation), and unsupervised representation learning.

Abstract: Disclosed are compounds of Formula I, methods of using the compounds for inhibiting KRAS activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with KRAS activity such as cancer.

Abstract: This disclosure describes a system, method, and non-transitory computer readable media for an ultrasound probe configured to capture ultrasound images of an examination region. The system includes a first set of one or more sensors coupled to the ultrasound probe and configured to estimate a first positional information associated with the ultrasound probe. The system includes a second set of one or more sensors coupled to the ultrasound probe and configured to capture electromagnetic force (EMF) measurements in the examination region to estimate a second positional information associated with the ultrasound probe. The second positional information is used to calibrate the first set of one or more sensors. The system includes a controller configured to use at least one of (i) the first positional information, or (ii) the second positional information to generate a reconstruction of the examination region based on ultrasound images captured by the ultrasound probe.

Abstract: The invention relates to a battery device (10) for a motor vehicle, having a plurality of battery cells (12) which are accommodated in a housing and rest at least against a heat-conducting potting compound (20) or a heat-conducting pad, which potting compound or pad rests against at least one structural component (22) of the battery device (10), as a result of which heat (14) can be dissipated from the battery cells (12) to the structural component (22) via the heat-conducting potting compound (20) or the heat-conducting pad.

Abstract: In one embodiment, a method for scheduling tasks comprises, at a task scheduler of a processing node of a plurality of processing nodes: retrieving a first task descriptor from a local memory of the task scheduler, the task descriptor corresponding to a task scheduled for execution at the current time and comprising at least a task execution time, a frequency for performing the task, and a task identifier; determining whether the task descriptor is assigned to the task scheduler for execution; if it is determined that the task descriptor is assigned to the task scheduler for execution: executing the task; updating the task execution time based on the current task execution time and the frequency for performing the task; and re-queuing the task descriptor in the local memory.

Abstract: Apparatuses (e.g., devices, systems, etc.) and methods that may provide access to one or more tools to a remote site in the body including expandable and external working channels that may be part of a tube that is coupled to an outer surface of an elongate medical device, such as an endoscope.

Abstract: A process to form a rheology modified composition, the process comprising applying radiation, and optionally heat, to a composition that comprises at least the following component: a) an olefin-based polymer comprising a total unsaturation ?0.20 /1000 C; and wherein the radiation is applied using an electron beam (e-beam) at a dosage selected from 0.1 MRad to 1.5 MRad; and wherein component a is selected from a telechelic polyolefin of the formula A1L1L2A2, an unsaturated polyolefin of the formula A1L1, or an ethylene/alpha-olefin interpolymer. A process to form a rheology modified composition, the process comprising applying heat, and optionally radiation, to a composition that comprises at least the following components: a) an olefin-based polymer, as described above, comprising a total unsaturation ?0.20/1000 C; b) from 1.0 to 100 ppm of a peroxide, based on the weight of the composition.

Abstract: An optical assembly (100) for use in a wearable device is provided, the assembly (100) comprising: a prism (104), a photonic integrated chip, PIC (108), a substrate layer (106), and a lid (102); wherein the PIC (108) is mounted onto the substrate layer (106); the prism (104) comprising: (i) a first input/output surface (112) optically coupled to the PIC (108), and (ii) a second input/output surface (114) optically coupled to the lid (102), the second input/output surface (114) orientated perpendicularly to the first input/output surface (112), and wherein the prism (104) provides an optical path and reflects a percentage of light from the first input/output surface (112) to the second input/output surface (114). Methods of manufacturing such an optical assembly are also provided.

Abstract: A lab system identifies a set of steps associated with a protocol for a lab meant to be performed by a robot within the lab using equipment and reagents. The lab system renders, within a user interface, a virtual representation of the lab, a virtual robot, and virtual equipment and reagents. Responsive to operating in a first mode, the lab system simulates the identified set of steps identify virtual positions of the virtual robot within the lab as the virtual robot performs the steps and modifies the virtual representation of the lab to mirror the identified positions of the virtual robot in real-time. Responsive to operating in a second mode, the lab system identifies positions of the robot within the lab as the robot performs the identified set of steps and modifies the virtual representation of the lab to mirror the identified positions of the robot in real-time.

Abstract: A lab system accesses a first protocol for performance by a first robot in a first lab. The first protocol includes a set of steps, each associated with an operation, reagent, and equipment. For each of one or more steps, the lab system modifies the step by: (1) identifying one or more replacement operations that achieve an equivalent or substantially similar result as a performance of the operation, (2) identifying replacement equipment that operates substantially similarly to the equipment, and/or (3) identifying one or more replacement reagents that, when substituted for the reagent, do not substantially affect the performance of the step. The lab system generates a modified protocol by replacing one or more of the set of steps with the modified steps. The lab system selects a second lab including a second and configures the second robot to perform the modified protocol in the second lab.