Abstract: Systems for producing an aerosol and related methods of use are described.

Abstract: In some embodiments, usage of a personal care device in compliance with a recommended use is improved. A usage monitor computing device may detect and store records of use of the personal care device. The usage monitor computing device may transmit the records of use to a monitoring server device via a network. The usage monitor computing device may determine whether the records of use indicate that the personal care device has been used as directed by the recommendations, and if so, may determine whether one or more rewards for use should be provided to the user. The usage monitor computing device may receive notifications of the rewards, and may present notifications of the rewards to the user.

Abstract: A personal care device that is capable of two-way communication is provided. In some embodiments, the personal care device operates in a first mode and a second mode depending on whether a signal has been received from a networked computing device, thus allowing a single human-machine interface (HMI) device to both control the personal care device and to cause signals to be sent to the networked computing device. In some embodiments, the personal care device is configured to present media streamed from the networked computing device, and/or to stream audio detected by the personal care device to the networked computing device.

Abstract: A PET detector array (8) comprising detector pixels acquires PET detection counts along lines of response (LORs). The counts are reconstructed to generate a reconstructed PET image (36, 46). The reconstructing is corrected for missing LORs which are missing due to dead detector pixels of the PET detector array. The correction may be by estimating counts along the missing LORs (60) by interpolating counts along LORs (66) neighboring the missing LORs. The interpolation may be iterative to handle contiguous groups of missing detector pixels. The correction may be by computing a sensitivity matrix having matrix elements corresponding to image elements (80, 82) of the reconstructed PET image. In this case, each matrix element is computed as a summation over all LORs intersecting the corresponding image element excepting the missing LORs. The computed sensitivity matrix is used in the reconstructing.

Abstract: Cartridges configured for use in a hair treatment device include a pouch having an outlet, a capsule located within the pouch, and a fitment sealed within the outlet of the pouch. The pouch contains a first product and the capsule contains a second product.

Abstract: An apparatus automatically places, forms and compacts an adhesive strip on an edge of a structure in a single pass.

Abstract: A system for treating a surface and applying adhesive to an already treated portion of the surface concurrently is presented. The system comprises surface treatment equipment, adhesive application equipment, and a common feed system. The surface treatment equipment is configured to treat the surface of an elongated member. The adhesive application equipment is configured to apply adhesive to the already treated portion of the surface. The common feed system feeds the elongated member beneath the surface treatment equipment and the adhesive application equipment concurrently.

Abstract: A non-transitory computer-readable medium stores instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform an image reconstruction method (100). The method includes: determining a weighting parameter (13) of an edge-preserving regularization or penalty of a regularized image reconstruction of an image acquisition device (12) for an imaging data set obtained by the image acquisition device; determining an edge sensitivity parameter (?) of the edge-preserving algorithm for the imaging data set obtained by the image acquisition device; and reconstructing the imaging data set obtained by the image acquisition device to generate a reconstructed image by applying the regularized image reconstruction including the edge-preserving regularization or penalty with the determined weighting and edge sensitivity parameters to the imaging data set obtained by the image acquisition device.

Abstract: Systems, devices, and methods are described for allowing users to, among other things, rate specific occurrences of an event, including receiving one or more inputs associated with an event; generating a user interface presenting a rating menu and receiving one or more inputs indicative of a rating associated with the event based on the rating menu; and generating event rating information based on receiving the one or more inputs indicative of the rating associated with the event.

Abstract: In some embodiments, an authorization server device receives a request for an activation token to activate a personal care device. The authorization server device determines an authorized usage amount, and generates an activation token based on the authorized usage amount to be transmitted to the personal care device. Activation of a personal care device may be authorized based on consumable products obtained for use with the personal care device. By limiting activation of the personal care device based on consumable products obtained for use with the personal care device, the technical problems in overuse of some consumable products (such as brush heads) or underuse of other consumable products (such as serums or cleansers) can be avoided, and maximum results from use of the personal care devices can be easier to obtain.

Abstract: The invention provides a composition of glucocerebrosidase, such as velaglucerase alfa, and isofagomine, in a molar ratio of at least about 1:2.5. Also provided is a use of the composition for treatment of a disorder related to a dysfunction in a GCase pathway. The disorder could be a lysosomal storage disease, such as Gaucher disease, Fabry disease, Pompe disease, a mucopolysaccharidoses, or multiple system atrophy. The disorder could also be a neurodegenerative disorder, such as Parkinson disease, Alzheimer's disease, or Lewy body dementia. The composition can have 0.5 to 5.0 mg/kg of glucocerebrosidase and isofagomine in at least about a 3-fold molar excess to the glucocerebrosidase. The composition can be administered intravenously or subcutaneously.

Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of plasma kallikrein and which exhibit desirable characteristics for the same.

Abstract: Abrading apparatus and methods for treating opposing web surfaces of an elongate part include engaging the surfaces with first and second abrasion devices coupled to a frame. A drive assembly advances the frame along the part while the abrasion devices are operated to treat the surfaces. A guard assembly is coupled to the frame and includes first and second guards positioned to block portions of the contact areas of the first and second abrasion devices.

Abstract: A non-transitory computer-readable medium storing instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform a quality control (QC) method (100). The method includes: receiving a current QC data set acquired by a pixelated detector (14) and one or more prior QC data sets acquired by the pixelated detector; determining stability levels of detector pixels (16) of the pixelated detector over time from the current QC data set and the one or more prior QC data sets; labeling a detector pixel of the pixelated detector as dead when the stability level determined for the detector pixel is outside of a stability threshold range; and displaying, on a display device (24) operatively connected with the workstation, an identification (28) of the detector pixels labelled as dead.

Abstract: Devices and methods for electrostatic application of cosmetics are described. In one embodiment, a system for electrostatic deposition of cosmetic material on a surface includes: a housing; a nozzle configured for breaking the cosmetic material into cosmetic particles and for directing the cosmetic particles out of the housing and toward the surface; and a reservoir configured for holding the cosmetic material. The reservoir is connected to the nozzle. The system also includes an airflow conduit configured to provide air to the nozzle; and a nozzle electrode configured proximately to the nozzle. The nozzle electrode is configured to charge the cosmetic particles.

Abstract: Optical connectors may include various portions, or structures, to provide a plurality of degrees of movement to optical ferrules. The optical ferrules may be linearly movable along one or more axes and rotationally moveable about one or more axes for alignment and coupling to corresponding optical ferrules. The optical connectors may be integrated with, or in conjunction with, other non-optical connectors such as electrical connectors, e.g., located on a drive carrier.

Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of plasma kallikrein and which exhibit desirable characteristics for the same.

Abstract: A skincare device having a brush head configured to contact a face of a user is presented. The brush head includes a plurality of bristles configured to oscillate about a center point, and a thermal element configured to heat or cool skin of the user. In some embodiments, the thermal element includes a thermal element vessel, and a thermal element filler inside the thermal element vessel.

Abstract: Systems and methods for manufacturing eyelash prostheses are described.

Abstract: The present disclosure relates, in various embodiments, to methods and systems for masking and de-masking a portion of an interior surface of a structure, such as may be useful in the selective coating of an interior surface of a structure. The method comprises providing a masking device comprising a magnetically active material and a seal-forming material and inserting the masking device into an interior of the structure. A magnetic force is activated in order to bring the masking device into sealable contact with a portion of an interior surface of the structure, thereby producing a masked portion of the interior surface. While maintaining the sealable contact, the unmasked portion of the interior surface of the structure is coated with a coating material. After the coating, the magnetic force is deactivated in order to bring the masking device out of sealable contact with the interior surface of the structure.