Abstract: The invention provides a biomedical detection photoelectric module, which includes a circuit substrate, a plurality of isolating barriers, a light-emitting unit, a photosensitive unit, and a light-guiding assembly. The light-guiding assembly provides a first optical element and a second optical element, respectively, corresponding to a light-emitting unit and a light-sensing unit. The first optical element has a first pattern layer to alter the emitting angle of the first light generated by the light-emitting unit. The second optical element has a second pattern layer to alter the incident angle of a second optical element entering the light-sensing unit. The first light is guided by the first optical element so that the energy of the first light is concentrated and incident on a predetermined area of a human's skin layer. The second light in the predetermined area is guided by the second optical element to enter the light-sensing unit.

Abstract: The present disclosure relates to the technical field of coatings. In order to prepare a polyphenol coating more efficiently and gently on the surface of a material, the present disclosure provides a preparation method of a polyphenol coating, including the following steps: (1) preparing a Tanfloc aqueous solution; (2) adjusting the Tanfloc aqueous solution obtained in step (1) to be in a colloidal suspension state to obtain a modified solution; and (3) placing a carrier material in the modified solution prepared in step (2) to obtain a modified coating on a surface of the carrier material. In the present disclosure, by the preparation method of a polyphenol coating, the polyphenol coating can be efficiently prepared on a material surface under mild conditions.

Abstract: The invention provides a sidelight-type non-invasive glucose monitoring module, which includes a substrate, an sidelight-type light source assembly, an sidelight-type light sensing assembly and a blocking member. The sidelight-type light source assembly is arranged on the substrate and includes a light-emitting element and a first light-guiding element. The sidelight-type light sensing assembly is arranged on the substrate and includes a light-sensing element and a second light-guiding element. The blocking member is arranged between the sidelight-type light source assembly and the sidelight-type light sensing assembly to block the sidelight-type light source assembly from the sidelight-type light sensing assembly.

Abstract: The present invention relates to an autoinjector device (10) for use in combination with a syringe (30), said syringe comprising a movable plunger; a needle; and a tubular needle shield (34). The claimed autoinjector device (10) comprises: an elongated housing having a proximal (11) and a distal end (12); a drive mechanism; a syringe holder (40) in order to support the fragile syringe and to prevent damage to the syringe. The invention furthermore relates to a method for assembly of the autoinjector device according to the invention.

Abstract: The present invention provides an intelligent attention rehabilitation system, which includes a gaze tracking module, an attention evaluation module, an intelligent computation and program push module, a data storage module, and an assessment and feedback module. In the invention, based on the theoretical CMA, data on attention level is acquired; and the advantages of simple configuration requirements and low cost of the gaze tracking technology, and intelligent computation of AI algorithms are used, to digitally evaluate attention of a subject. Besides, the DQN algorithm is used to realize intelligent push of related attention training guidance and programs, to solve the problem of family attention rehabilitation training under the lack of scientific guidance in the market currently, thereby providing a more scientific and accurate family attention rehabilitation evaluation and training system for the need.

Abstract: The present invention relates to a series of substituted pyridine-2,4-dione derivatives and preparation methods therefor, and in particular, to a compound represented by formula (I) and a pharmaceutically acceptable salt thereof.

Abstract: A slide rail assembly includes a first rail, a second rail, a locking member, a driving member and an operating member. The second rail is movable relative to the first rail. The locking member is configured to lock the second rail relative to the first rail at a predetermined position. The driving member is movable relative to the second rail. When the operating member is moved from an initial position to a non-initial position, the operating member is configured to drive the driving member to move to further drive the locking member to move, in order to unlock the second rail relative to the first rail at the predetermined position.

Abstract: A method of accelerating the production of nitric oxide (NO) can include co-administering a generator of H2 with a generator of nitric oxide (NO) as a formulation to a subject. The generator of H2 includes elemental magnesium metal powder and the generator of NO is a nitrate, while the formulation is also free of amino acids.

Abstract: An inflatable pillow includes a pillow cover unit having an upper space and a lower space spaced apart from each other, a plurality of elastic hoses, and an inflatable air bag unit disposed in the lower space. The elastic hoses are disposed in the upper space, extend in a first direction, and are arranged in parallel to each other along a second direction substantially perpendicular to the first direction.

Abstract: An early assistive diagnosis system of ADHD provides a test to the subject and uses a brain-computer interface (BCI) to detect the electroencephalography (EEG) signals of subject. A host receives the EEG signals, captures the features associated with ADHD heterogeneities, obtains feature EEG signals, and classifies the subject as typical development or ADHD, then uses the EEG feature signals to train a predicted index score range for the heterogeneities of ADHD. The test scores of a new subject is tested, it is compared whether the scores fall within the predicted index score range to determine the ADHD heterogeneity types to which the new subject belongs. Thus, the present invention uses attention tests for ADHD in combination with EEG signals to assess symptoms of a subject, further predicts the potential aptitude of a subject for ADHD and provides objective assistive diagnosis to physicians.

Abstract: The present disclosure provides a chimeric antigen receptor (CAR) molecule comprising a modified hinge and transmembrane domain (HTM-1), wherein the modified hinge and transmembrane domain comprises the amino acid sequence of SEQ ID NO:2. Cells expressing CAR with the modified HTM-1 domain disclosed herein are expected to have enhanced anti-tumor activities with reduced release of pro-inflammatory cytokines.

Abstract: A slide rail mechanism includes a first slide rail assembly, a second slide rail assembly and an unlocking handle. Each of the slide rail assemblies comprises a first rail, a second rail and a locking member. The first rail and the second rail are movable relative to each other. The locking member is configured to lock the second rail relative to the first rail at a predetermined position. The locking handle is movably mounted between the first slide rail assembly and the second slide rail assembly. When the unlocking handle is moved from a first position to a second position, the unlocking handle is configured to drive the locking member to move in order to unlock the second rail relative to the first rail at the predetermined position.

Abstract: The presently disclosed subject matter provides for chimeric receptors that target MUC16 and cells comprising such chimeric receptors. The presently disclosed subject matter further provides uses of the chimeric receptors for treatment.

Abstract: The present disclosure relates to a cooking utensil with air frying and pressure cooker functions. The cooking utensil includes a cooker body (1), an inner pot (2), a lid (4), and a heating plate (5); the cooker body (1) includes a middle housing (15) and an outer housing (23); the heating plate (5) is arranged above a bottom surface of the middle housing (15); the inner pot (2) is arranged in an inner cavity of the middle housing (15). When the air frying subassembly (3) is put into the cooker body, the fan subassembly works, and the centrifugal air turbine (12) draws air in the cavity of the middle housing (15) into the bottom surface of the middle housing (15) and exchanges heat with the heating plate (5) to cook food.

Abstract: Surface coverings, such as floor coverings, with an interlocking design are described. Methods of making the surface coverings are further described. A plank including a resilient composite sheet having four sides, an upper surface, a lower surface, and an overall thickness, and said composite sheet comprising at least one base layer, wherein said at least one base layer comprising at least one polymeric material and at least one filler, wherein opposite sides of the composite sheet comprise a first tongue on a first side and a first groove on the opposite second side, wherein the first tongue and first groove have complementary shape to each other to be interlockingly engageable with a corresponding groove or tongue on an adjacent floor plank.

Abstract: A novel toilet seat structure, including a supporting base, a toilet seat, fixing blocks and two first buffered-descent modules; the toilet seat includes a child seat that has a child seat body and a first decorative lid; a rear end of the child seat body is provided with a shaft portion including first shaft sleeves and a sliding groove; the first decorative lid is detachably fitted with an opening part of the sliding groove; two ends of the supporting base are provided with second shaft sleeves respectively; a fixing block is embedded inside and being limited from rotating circumferentially in each second shaft sleeve; each first buffered-descent module is embedded inside the shaft portion through the sliding groove, and then passes through a corresponding first shaft sleeve and is then connected to a corresponding fixing block.

Abstract: Example respiratory protective devices with improved sound insulation are provided. For example, an example respiratory protective device comprises an inner shell component and a fan mounting component. In some examples, the inner shell component defines at least one acoustic insulation portion that is indented on an outer surface of the inner shell component. In some embodiments, the fan mounting component protrudes from an indented surface of the at least one acoustic insulation portion and comprising a plurality of acoustic insulation ribs.

Abstract: The present application provides an air purifier comprising a main body, wherein the main body comprises: a housing, wherein an interior of the housing is hollow, an air inlet is formed at one end of the housing, an air outlet is formed at the other end of the housing, and positions of the air inlet and the air outlet are interchangeable; a fan mounted in the housing and used for sucking outside air from one end of the housing or for sucking outside air from the other end of the housing; a photocatalyst member mounted in the housing; and ultraviolet light-emitting members mounted in the housing, so that ultraviolet light emitted by the ultraviolet light-emitting members can effectively irradiate the photocatalyst member.

Abstract: A platform-based strength machine enables users to perform strength or lifting activities or exercises via moveable or configurable pull points. The strength machine can include tracks that facilitate the configuring of the positions of the pull points, handles that control operation of the strength machine and/or measure movements performed by a user, compact motors that facilitate various platform or load application configurations, safety systems for the strength machine, and other enhancements.

Abstract: Provided are gene therapy technologies, including specifically designed and tested guide RNA sequences for improved base editors, useful for increasing the expression of the gamma-globin gene. The guide RNA sequences may target the BCL11A erythroid enhancer or the gamma-globin promoter, or both at the same time. The base editors can include nucleobase deaminase inhibitor that inhibits the editing activity of the base editors until they are bound to the target sites. These gene therapy technologies are useful for treating diseases including beta-thalassemia and sickle cell anemia, among others.