Abstract: The invention provides novel phosphoinositide 3 kinase beta-selective inhibitors and pharmaceutical compositions thereof, as well as methods of their preparation and use, in therapy of various diseases and conditions, such as solid tumors.

Abstract: There is provided an electric traction system, comprising: a step-down transformer comprising a primary winding for operatively coupling to an AC power supply and a secondary winding which is inductively coupled to the primary winding; a traction converter module comprising a first input terminal and a second input terminal which are operatively coupled to the secondary winding, and a plurality of AC-to-AC power converters, each of which comprises first and second input nodes, configured to receive AC power and output nodes configured to supply AC power, wherein the first and second input nodes, of the plurality of AC-to-AC power converters are electrically connected in series between the first input terminal and the second input terminal; and at least one electric motor configured to be driven by the traction converter module.

Abstract: Compositions and methods for fluorescence activated cell analysis of blood cell populations.

Abstract: The disclosed technology concerns a method for wetting and dispersing a pulverulent polycarboxylic acid containing polymer in aqueous media without the need of a steric stabilizer and/or a wetting agent, said method comprises a) providing a pulverulent pre-neutralized carboxylic acid containing polymer or copolymer, wherein said polymer or copolymer is prepared from a monomer mixture comprising at least one olefinically unsaturated carboxylic acid group containing monomer, and wherein from about 1 to about 10 wt. % of said carboxylic acid group containing monomer(s) is neutralized; b) mixing said pulverulent pre-neutralized carboxylic acid containing polymer or copolymer in aqueous medium; and c) mixing a deswelling agent selected from an acid, a salt, and combinations thereof with said aqueous medium, and optionally d), adjusting the pH.

Abstract: The present disclosure provides a method and an apparatus for identifying a dark web website in a scenario where a plurality of pages are accessed simultaneously. The method includes: obtaining browsed network traffic packets of websites to be identified, and extracting direction sequence features from the network traffic packets; dividing the direction sequence features into a plurality of subsequence features based on a plurality of sliding windows, and inputting the plurality of subsequence features into a neural network model to extract preset pattern features; analyzing a correlation of the preset pattern features using a target website identification model to obtain a probability result of a target website being accessed; obtaining a target website identification result in the website to be identified based on the probability results and a preset classification model.

Abstract: The present disclosure discloses an acoustic output device. The acoustic output device may include at least one acoustic driver configured to generate sounds and a housing structure configured to carry the at least one acoustic driver. The housing structure may include a cavity, and the at least one acoustic driver may be arranged in the cavity and may divide the cavity into a first cavity and a second cavity. And the sounds generated by the at least one acoustic driver may be transmitted from the first cavity and the second cavity, respectively, pass through the housing structure, and form dual sound sources arranged on two sides of an auricle, respectively.

Abstract: The present disclosure provides a method for separating SSCs from a frozen testicular tissue, and belongs to the field of cell biology. In the present disclosure, the method includes the following steps: resuscitating a frozen testicular tissue, digesting the resuscitated testicular tissue with a collagenase IV and a DNase I until seminiferous tubules are exposed and tube walls become coarse; washing the digested testicular tissue with a DPBS, conducting centrifugation and culture until cells migrate; collecting the migrated cells, and enriching and purifying SSCs. The method can maintain a milieu interieur of the SSCs to the greatest extent, and therefore cell viability, and less cell damages. Therefore, the method can be used for the separation of SSCs from frozen testicular tissues.

Abstract: A system and method and for generating an editable document from a non-editable document includes automatically identifying a layout for a plurality of objects in the non-editable document, where the layout includes bounding boxes of one or more of the objects, and automatically identifying a font for a text object of the plurality of objects. The method and system also includes selecting a color scheme for one or more of the plurality of objects, the color scheme corresponding to one or more color values associated with the plurality of objects the non-editable document, before automatically generating the editable document in accordance with at least one of the identified layout, identified font and selected color scheme.

Abstract: A display panel includes: a backplane, a plurality of light-emitting devices, a plurality of connecting leads, a first protective layer and a reflective layer. The backplane includes a first main surface, a second main surface, and a plurality of side surfaces. At least one side surface is as a selected side surface. The plurality of light-emitting devices are disposed on the second main surface and are electrically connected to the plurality of connecting leads. The plurality of connecting leads are disposed on the first main surface, the selected side surface and the second main surface, and each connecting lead sequentially passes through the selected side surface and the second main surface from the first main surface. The first protective layer covers the plurality of connecting leads. The reflective layer includes at least a first portion covering a portion of the first protective layer on the selected side surface.

Abstract: A liquid yeast one- and two-hybrid high-throughput library screening method and use thereof changes the screening of solid medium to liquid culture solution screening, avoiding a large number of plate coating work, and avoiding the tedious work of identifying single colonies one by one, which not only saves experiment time, but also reduces the cost and workload; at the same time, the present invention also combines high-throughput sequencing technology to improve the analysis throughput of yeast hybridization screening work, and can also improve the automation level of analysis, and can greatly reduce false negatives. More importantly, the present invention can solve the phenomenon of protein self-activation. By changing to liquid screening, known protein interaction information can be successfully obtained, which provides a new opportunity for protein-protein interaction research.

Abstract: A transmission method and a communication apparatus provide a source access network device receives first data and a first identifier. The first identifier indicates a last data packet of the first data, and the first data is data in a first periodicity of a periodic service. The source access network device sends a handover command to a terminal device in a first time period. A start moment of the first time period is a moment at which the last data packet is sent, an end moment of the first time period is an end moment of the first periodicity, and the handover command instructs the terminal device to perform a handover to a target access network device. This avoids interruption of sending the first data by the source access network device due to the handover and improves transmission reliability of the periodic service.

Abstract: Disclosed is a device of automatically detecting nucleic acid, including: a fixing frame; a cartridge positioning assembly having a cartridge loading position configured to position a cartridge; a lifting assembly including a lifting base configured to be controllably moved toward or away from the cartridge positioning assembly in a first direction; a rotating assembly including a rotating member capable of controllably rotating relative to the lifting base around a rotation axis parallel to the first direction; and a liquid transferring assembly including a connecting portion configured to connect to a tip. The liquid transferring assembly is capable of rotating with the rotating member to a position where the connecting portion is aligned with any liquid storing tank of the cartridge in the first direction, the liquid transferring assembly is capable of moving along with the lifting base to an inserting position or a disengaging position along the first direction.

Abstract: The present disclosure relates to model training methods, scene recognition methods, and related devices. One example method includes obtaining a first image, recognizing an image of a target object irrelevant to scene recognition in the first image by using an object detection model, performing masking on a region in which the target object is located in the first image to obtain a third image, then generating a plurality of sample object images that are irrelevant to the scene recognition through an image generative model, combining the sample object image and the third image to obtain a target image, inputting the target image to a first convolutional neural network for training, and inputting the third image to a second convolutional neural network for training to obtain a scene recognition model.

Abstract: The present disclosure provides a method and system for motion data calibration, which can convert motion data during a movement of a user from three-dimensional posture data of a coordinate system whose three axes are mutually perpendicular to each other, to two-dimensional data under a target coordinate system, such that the movement of the user may be divided to a movement in a horizontal direction and a movement in a vertical direction. The method and system are capable of calibrating motion data without requiring the user to perform a calibration action.

Abstract: The present disclosure provides a method performed by user equipment in a wireless communication system and the device thereof. The method comprises: receiving configuration information transmitted by a base station, wherein the configuration information includes at least one of random access resource configuration information or message 3 resource configuration information; determining, by the user equipment, at least one of random access resources or message 3 resources associated with a first operation according to the configuration information, when the user equipment is to perform the first operation; and transmitting at least one of a random access preamble or message 3 according to the determined resources.

Abstract: There is provided a spectacle lens, including: a base region where a light flux incident from an object-side surface is emitted from an eyeball-side surface and converges on a retina through an eyeball; a plurality of defocus regions in contact with the base region and having a property that the light flux passing through at least a part of the defocus region is incident on a retina as a divergent light; and a first defocus region arrangement portion in which the plurality of defocus regions are arranged in such a manner that a 4 mm diameter circular region including only one defocus region exists in a circle in a planar view of the object-side surface.

Abstract: Embodiments of this application relate to a call system, an extension, and a host in the field of communication technologies. An example call system includes a host and an extension. A network side device and the host are connected through a network side link, and the host and the extension are connected through a first terminal side link. The extension exchanges a call data packet with the network side device through the first terminal side link and the network side link. The extension and the host transmit the call data packet through a second terminal side link in response to determining that call quality of the extension is lower than a quality threshold. The first terminal side link is different from the second terminal side link.

Abstract: Techniques for leveraging a distributed Domain Name System (DNS) infrastructure for preserving Personally Identifiable Information (PII) data for distributed resolvers using a hash to policy pair (HPP) database are described. A DNS security service receives metadata including PII associated with a client. A cryptographic hash function is applied to the metadata including PII associated with the client to generate a client hash value. A client HPP is created by mapping the client hash value to a set of DNS policy instructions associated with the client. The client HPP is stored in a HPP database. A distributed resolver is authorized to provide DNS services to the client. Finally, the HPP database is published to the distributed resolver.

Abstract: In some examples, the semiconductor structures include a stack structure, a plurality of conductive structures and a first insulating layer. The stack structure may include a plurality of first dielectric layers and gate layers which are alternately disposed; the stack structure may have a memory region and a connection region, the stack structure in the connection region may include a plurality of first dielectric layers and second dielectric layers. The plurality of conductive structures may be disposed in the connection region. The conductive structure includes conductive portions insulated from each other, each conductive portion penetrates through part of the stack structure and is connected with the gate layers. Parts of the conductive portions that penetrate through the stack structure may be disposed in a nested manner. The semiconductor structure is applied to a three-dimensional memory, so as to implement reading and writing operations of data. Other examples are disclosed.

Abstract: The disclosure relates to a 5G or 6G communication system for supporting a higher data transmission rate. A method performed by user equipment UE is disclosed, and includes receiving resource random access related configuration information, wherein the resource configuration information includes frequency domain configuration information of M random access occasions (ROs); determining resource locations of the M ROs based on the resource configuration information; and sending a random access preamble/channel at the determined resource locations.