Abstract: A system and method for utilizing an activity monitoring device that includes, during a set of initial activity sessions, collecting the kinematic data from an activity monitoring device and generating a temporal record of at least one biomechanical signal that is calculated from the kinematic data; analyzing temporal changes in the biomechanical signals during the initial activity sessions and characterizing a fatigue model; and, during a subsequent activity session collecting current kinematic data of a participant and generating at least one current biomechanical signal from the current kinematic data, monitoring the fatigue state through processing the at least one current biomechanical signal according to the fatigue model, and triggering feedback in a user interface based on the fatigue state.

Abstract: In general, techniques are described by which provide a technique for securely updating sub-systems of a device. A device includes multiple sub-systems including a first sub-system and a second sub-system. Each sub-system includes one or more processors. One or more processors of the first sub-system may be configured to perform the techniques herein. The one or more processors of the first sub-system are configured to download, from one or more nodes of a network, a sub-system update for the second sub-system in response to detecting an update to a ledger of a blockchain associated with the second sub-system. The one or more processors of the first sub-system are further configured to distribute the sub-system update for the second sub-system to the second sub-system.

Abstract: In a washing element holder (2), which on one side is closed off relative to the outside (s) with a sponge material (5) having pores (4), a washing device (1) has a washing element (3) which has at least one synthetic surfactant as a foaming substance and the principal constituent.

Abstract: A method for the computer-aided characterization of a circuit comprising a semiconductor layer and a semiconductor component region embedded in the semiconductor layer in an electrically insulated manner, wherein the semiconductor component region is optionally coupled to a dielectric layer structure to be protected, the method comprising determining an indication representing vis-à-vis the semiconductor layer an intensity of an electrical charging of the semiconductor component region by a production process used to produce the circuit, wherein a physical construction of the semiconductor component region is taken into account when determining the indication, and classifying the semiconductor component region taking account of the indication.

Abstract: The invention provides a method for preparing phenols from aromatic compounds, particularly a method of preparing phenol by direct hydroxylation of benzene. The method comprises contacting benzene with nitrous oxide in the presence of a bimetallic zeolite catalyst at an ambient pressure and a reaction temperature ranging from (about) 320° C. to 440° C.

Abstract: In general, techniques are described by which provide verification of parts installed to a device. A device comprising one or more sensors one or more processors implemented in circuitry may be configured to perform the techniques herein. The one or more processors are in communication with the one or more sensors and are configured to determine, in response to detecting an installation of a component for the device, an operating characteristic of the component measured by the one or more sensors. The one or more processors are further configured to verify, based at least in part on a comparison of the operating characteristic of the component and an approved operating characteristic for the component stored in a blockchain, that the component is an approved component for the device.

Abstract: In general, techniques are described by which provide a technique for securely updating sub-systems of a device. A device includes multiple sub-systems including a first sub-system and a second sub-system. Each sub-system includes one or more processors. One or more processors of the first sub-system may be configured to perform the techniques herein. The one or more processors of the first sub-system are configured to download, from one or more nodes of a network, a sub-system update for the second sub-system in response to detecting an update to a ledger of a blockchain associated with the second sub-system. The one or more processors of the first sub-system are further configured to distribute the sub-system update for the second sub-system to the second sub-system.

Abstract: A method for producing unsaturated macrocyclic monoketones comprising the following steps: (a) preparing macrocyclic dienes with a ring size of at least 9 carbon atoms; (b) contacting the starting materials from step (a) with (b1) a palladium(II) salt and/or a palladium(II) complex; and (b2) an oxidant; and (b3) a solvent; and optionally (b4) a ligand; and optionally (b5) a co-catalyst; and optionally (b6) an acid.

Abstract: The presently described technology provides compositions comprising aryl carboxylic acids and, for example NSAIDs, chemically conjugated to oxymorphone (4,5-?-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one) to form novel prodrugs/compositions of oxymorphone, including benzoates, salicylates, propionates, fenamates, and acetates, which have a decreased potential for abuse of oxymorphone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology.

Abstract: A device for detaching a burr from an opening of a transverse borehole of a workpiece includes an elongate shank for positioning in a longitudinal borehole of the workpiece and a fillet to avoid the elongate shank colliding with a drill for drilling the transverse borehole. In an example embodiment, the device has an aperture to further avoid the elongate shank colliding with the drill. In an example embodiment, the elongate shank has a cutting section with a cutting edge for detaching the burr from the opening of the transverse borehole.

Abstract: A video-on-demand system including a video server storing video-on-demand content and for streaming video-on-demand through a first layer of an internet page having a first layer and a second layer; and a controller for causing there to be formed in the second layer a plurality of selectable overlay images such that a user at a location in communication with the internet remote from the video server and the controller can display streamed video-on-demand of the first layer in combination with the overlay images of the second layer and can select one of the overlay images; wherein the overlay images correspond to respective control functions for the video-on-demand stream; and the controller is responsive to selection of an overlay image to change the video-on-demand stream in accordance with the corresponding respective control function.

Abstract: A method for the computer-aided characterization of a circuit comprising a semiconductor layer and a semiconductor component region embedded in the semiconductor layer in an electrically insulated manner, wherein the semiconductor component region is optionally coupled to a dielectric layer structure to be protected, the method comprising determining an indication representing vis-à-vis the semiconductor layer an intensity of an electrical charging of the semiconductor component region by a production process used to produce the circuit, wherein a physical construction of the semiconductor component region is taken into account when determining the indication, and classifying the semiconductor component region taking account of the indication.

Abstract: A system and method for collecting a set of kinematic data streams from an activity tracking system with at least one activity monitoring system that is attached to a user; segmenting at least a subset of the kinematic data streams into a set of segments according to actions of the user; generating a set of biomechanical signals from the kinematic data streams wherein a biomechanical signal characterize a biomechanical property during a segment and includes generating a first integration data set through data integration and baseline error correction across the set of segments of the normalized kinematic data stream and determining at least a first biomechanical signal that is at least partially based on the first integration data set; and applying the set of biomechanical signals.

Abstract: The presently described technology provides compositions comprising aryl carboxylic acids and, for example NSAIDs, chemically conjugated to oxymorphone (4,5-?-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one) to form novel prodrugs/compositions of oxymorphone, including benzoates, salicylates, propionates, fenamates, and acetates, which have a decreased potential for abuse of oxymorphone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology.

Abstract: The presently described technology provides compositions comprising aryl carboxylic acids and, for example NSAIDs, chemically conjugated to oxycodone (4,5-?-epoxy-14-hydroxy-17-methylmorphinan-6-one) to form novel prodrugs/compositions of oxycodone, including benzoates, salicylates, propionates, fenamates, and acetates, which have a decreased potential for abuse of oxycodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology.

Abstract: A system and method are described herein for a sensor device which biomechanically detects in real-time a user's movement state and posture and then provides real-time feedback to the user based on the user's real-time posture. The feedback is provided through immediate sensory feedback through the sensor device (e.g., a sound or vibration) as well as through an avatar within an associated application with which the sensor device communicates. The sensor device detects the user's movement state and posture by capturing data from a tri-axial accelerometer in the sensor device. Streamed data from the accelerometer is normalized to correct for sensor errors as well as variations in sensor placement and orientation. Normalization is based on accelerometer data collected while the user is wearing the device and performing specific actions.

Abstract: A method for regulating parameters of at least two bioreactor bags individually, which bioreactor bags are provided on one and the same rocking part of a bioreactor system. The method includes the steps of: determining an individual weight of the content in each bioreactor bag at different points in time during processing; regulating one or more parameters in each bioreactor bag in dependence of the individual weights.

Abstract: The presently described technology provides compositions comprising aryl carboxylic acids and, for example NSAIDs, chemically conjugated to oxymorphone (4,5-?-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one) to form novel prodrugs/compositions of oxymorphone, including benzoates, salicylates, propionates, fenamates, and acetates, which have a decreased potential for abuse of oxymorphone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology.

Abstract: In a washing element holder (2), which on one side is closed off relative to the outside (s) with a sponge material (5) having pores (4), a washing device (1) has a washing element (3) which has at least one synthetic surfactant as a foaming substance and the principal constituent.

Abstract: In a washing element holder (2), which on one side is closed off relative to the outside(s) with a sponge material (5) having pores (4), a washing device (1) has a washing element (3) which has at least one synthetic surfactant as a foaming substance and the principal constituent.